CN104055685A - Bioactive micro-molecule polypeptide keratin essence - Google Patents
Bioactive micro-molecule polypeptide keratin essence Download PDFInfo
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- CN104055685A CN104055685A CN201410280021.3A CN201410280021A CN104055685A CN 104055685 A CN104055685 A CN 104055685A CN 201410280021 A CN201410280021 A CN 201410280021A CN 104055685 A CN104055685 A CN 104055685A
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Abstract
The invention discloses a bioactive micro-molecule polypeptide keratin essence, which comprises keratin, Glycyrrhiza glabra, oat bioactive peptide, glycerin, hydrogenated polyisobutene, glyceryl stearate, methyl glucose sesquistearate, simmondsia chinensis seed oil and a preservative. The essence is characterized in that the preservative is a plant preservative containing 20-40 parts by weight of a Rhubarb extract, 10-25 parts by weight of a pomegranate peel extract, 10-25 parts by weight of magnolia officinalis extract, 10-35 parts by weight of a saxifrage extract, and 10-15 parts by weight of an acanthopanax trifoliatus extract. The invention can be applied to the technical field of essence, the invention can realize effective reduction of the amount of synthetic preservatives by adding natural plant preservatives, and can further guarantee security of essence.
Description
Technical field
The present invention relates to a kind of essence, especially a kind of biological activity micromolecule polypeptide keratin essence.
Background technology
In prior art, essence, essence and facial film class skin care item kind on beauty treatment market are more and more; Now contrast as follows for a few money skin-protection products of main flow on market:
Contrast 1: Sheng Dijia biologically active peptide multiple-effect essence essence, deionized water, biologically active peptide, Radix Hamamelidis Mollis extracting solution, 1,3 butylene glycol, aminoacid Moisture factor, Radix Glycyrrhizae extract, vitamin B3, hyaluronic acid, Herba Centellae extract, arnica montana extract, collagen protein, Aloe original juice, ethyl hydroxybenzoate.
My white black skin care item of scheming-black pearl mercerising profit of contrast 2:My Scheming; Composition: water, glycerol, Sorbitol, sodium polyacrylate, pantothenylol, butanediol, nicotiamide, hydrolyzed pearl, propylene glycol, Cremophor RH40, glycyrrhizic acid dipotassium, hydrolyzed silkworm silk, xanthan gum, glycosyl trehalose, hyaluronate sodium, ethoxy urea, iodine propilolic alcohol butyl mephenesin Carbamate, Methylisothiazolinone, daily essence.
Contrast 3: the crystal-clear anti-acne essence of gloomy water in field; Composition: water, 1,3-butanediol, scutellariae,radix extract, Flos Chrysanthemi water, ginger-root extract, hyaluronate sodium, glycosyl trehalose, hydrogenated starch hydrolysate, glycerol, sorbitol, bisabolol, tridecyl alcohol polyethers-9, caprylyl glycol, 1,2-hexanediol, TMPD/adipic acid/glycerol cross linked polymer, propylene glycol, allantoin.
For the skin-protection product of above-mentioned main flow, be not difficult to find out: in prior art, the additive using in facial treatment essence liquid on market, essence is the antiseptic of the synthetic types such as sodium benzoate, potassium sorbate, phenoxyethanol, methyl hydroxybenzoate, ethyl hydroxybenzoate, butyl hydroxybenzoate, propyl hydroxybenzoate, ethyl hydroxybenzoate, allantoin, has in actual use certain potential safety hazard.But along with the raising of market demands, female consumer wishes to use a certain amount of natural plants antiseptic in essence, to reduce the use amount of synthetic antiseptic; Thereby improve to a certain extent the safety of essence.
Prior art contrast 1, is selected from application number: 200610042802.4, and title: natural-plant food antiseptics; Component: extract 70 weight portions of Flos Caryophylli, extract 25 weight portions of Cortex Cinnamomi, extract 5 weight portions of Corm Eleocharitis skin; Preparation method: Flos Caryophylli, Cortex Cinnamomi, Corm Eleocharitis skin are washed respectively to strive and dry, distillation extraction twice, each two hours, merge extractive liquid; Under 60 DEG C of conditions, it is the Tween 80 of 3%-5% that extracting solution is added to gross weight at reactor, carries out fully emulsifiedly, after the easy solubilising of ethanol with 10%, obtains extracting solution; And then be diluted to concentration 2.0mg/ml with sterilized water, finally obtain antiseptic liquid stand-by.
Prior art contrast 2, is selected from application number: 200710191998.8, and title: the natural plant source antiseptic agent of applying in a kind of low-temperature meat product; Component: 6.5 parts of Flos Caryophylli powder alcohol extracts, 1.5 parts of Rhizoma Zingiberis Recens powder alcohol extracts, 2.0 parts of anistree powder extracting solution.Preparation method: fragrant, anistree, Rhizoma Zingiberis Recens is pulverized respectively rear mistake 40 mesh sieves, gets minus sieve powder and extracts.Flos Caryophylli powder, Rhizoma Zingiberis Recens powder, anistree powder use 60%-95% ethanol extraction 3 hours with the solid-to-liquid ratio of 1: 10 separately, remove by filter residue, the extracting solution of three kinds of spices is concentrated into stock solution, and (stock solution refers to herein: in 1mL extracting solution, contain the raw-material extract of 1g, be 1g/1mL), then composite according to the volume ratio of 6.5 parts of Flos Caryophylli powder alcohol extracts, 1.5 parts of Rhizoma Zingiberis Recens powder alcohol extracts, 2.0 parts of anistree powder extracting solution; Finally obtain antiseptic liquid stand-by
Repeat anti-microbial property experimental procedure, must have antiseptic check analysis data, in table 4;
Table 4: existing antiseptic check analysis table (mm of unit)
According to above-mentioned prior art check analysis, known; The above-mentioned plant antiseptic agent embodiment that the application provides is in application, and its antibacterial effect is obviously because prior art contrast 1, prior art contrast 2 antibacterial effect.
The above-mentioned plant antiseptic agent embodiment that the application provides, has utilized the outstanding anti-microbial properties such as Radix Et Rhizoma Rhei, Pericarpium Granati, magnolia officinalis rehd.et wils.var.biloba rehd.et wils., Herba Saxifragae and thorn Acanthopanan trifoliatus (L.) Merr. cleverly, and the natural performance of plant; In conjunction with existing scientific and technological equipment, and carry out repeatedly creationary experiment and draw preferably extracting solution preparation method and the each component ratio relation of antiseptic; Its final antibacterial effect of realizing is far superior to the antibacterial effect of plant antiseptic agent of the prior art.
The anti-microbial property test of the biological activity micromolecule polypeptide keratin essence that 2, contains this plant antiseptic agent;
Accordingly, the invention provides multiple essence specific embodiments that contain this plant antiseptic agent, specifically comprise essence embodiment 1-9; Each essence embodiment parameter is in table 5;
Table 5 is containing the essence parameter list of natural plants antiseptic
The preparation process of above-mentioned essence provided by the invention can adopt the conventional preparation technology of those skilled in the art, is specifically summarized as follows:
By the Glycyrrhiza glabra L. in parameter list, keratin, biological activity micromolecule polypeptide (specifically can adopt oat active peptide), glycerol, PEG-20 Glucate SS, encircle five polydimethylsiloxane, Parleam, glyceryl stearate, half times of stearic acid of methyl glucoside, Jojoba seed oil, Argireline, carnosine, carbomer, essence, hyaluronate sodium, Methylisothiazolinone, plant antiseptic agent embodiment 1, plant antiseptic agent embodiment 3 is dissolved in deionized water, and add arginine to carry out pH value adjusting, adjusting pH value is 6-7.5, and low temperature is placed 24h.It should be noted that, for the ease of follow-up test experience, above-mentioned low-temperature operation can DEG C-2 DEG C of temperature ranges store in temperature-5, after 24h, each embodiment liquid sample storing is carried out to next step experiment.
Now above-mentioned essence embodiment 1-9 provided by the invention is carried out to validity check by conventional preservation challenge experimental technique; It should be noted that, specifically adopting which kind of method to test is those skilled in the art's conventional techniques hands section; Its main purpose is the mutual comparing result analyzing between above-mentioned multiple essence embodiment, as long as final data can reflect the mutual relation between embodiment.Concrete, preservation challenge experimental technique can be: each embodiment inoculates 6 times, inoculation in 1 week 1 time; 25ml base material adds 0.1ml strain (107-108cfu mL
-1), each embodiment does one and does not connect the contrast of strain blank experiment simultaneously; Concrete, preservation challenge experimental data is in table 6;
Table 6: preservation challenge experimental data table
Explanation of tables:
B:Bacteria antibacterial (staphylococcus aureus, have a liking for root cock Salmonella, day ditch dimension enterobacteria, escherichia coli, Klebsiella pneumonia, bacillus pyocyaneus, pseudomonas fluorescens, pseudomonas putida)
M:mold mycete (Aspergillus niger, penicillium)
Y:Yeasts yeast (Candida albicans)
-: do not increase; +: slightly increase; ++: moderate increases; +++: seriously increase;
Known according to above-mentioned preservation challenge experiment:
Summary of the invention
The technical problem that the present invention solves is to provide a kind of biological activity micromolecule polypeptide keratin essence, can solve existing problem in present technology, can be by adding natural plants antiseptic, realize the addition that effectively reduces synthetic antiseptic, can further effectively ensure the safety of essence.
For solving the problems of the technologies described above, the invention provides a kind of keratin essence, comprise keratin, Glycyrrhiza glabra L., oat active peptide, glycerol, Parleam, glycerol stearic acid, half times of stearic acid of methyl glucoside, Jojoba seed oil and antiseptic, it is characterized in that; Described antiseptic is plant antiseptic agent, and described plant antiseptic agent comprises:
Radix Et Rhizoma Rhei extract 20-40 weight portion;
Pericarpium Granati extracting solution 10-25 weight portion;
Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution 10-25 weight portion;
Herba Saxifragae extracting solution 10-35 weight portion;
Thorn Acanthopanan trifoliatus (L.) Merr. extracting solution 10-15 weight portion;
The preparation technology of described Radix Et Rhizoma Rhei extract comprises 100 mesh sieves are pulverized and crossed to Radix Et Rhizoma Rhei dry tablet, and to add concentration be 70% ethanol extraction agent, carries out the ultrasonic Treatment operation of 35min; Carry out the operation of constant temperature reflux, extract,, reflux temperature is 60 DEG C, and the time is 1h; Finally extracting liq is carried out obtaining Radix Et Rhizoma Rhei extract after vacuum filtration, distilling under reduced pressure concentration operation;
The preparation technology of described Pericarpium Granati extracting solution comprises and Pericarpium Granati pulverized and crossed 50 mesh sieves, and to add concentration be 60% ethanol extract, solid-liquid ratio 1g: 30ml; Under 35 DEG C of temperature conditions, after lixiviate, filter; After extraction time 7h, obtain filtrate, will after filtrate evaporation and concentration, obtain Pericarpium Granati extracting solution;
The preparation technology of described magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution comprises and magnolia officinalis rehd.et wils.var.biloba rehd.et wils. pulverized and crossed 50 mesh sieves, and to add concentration be 60% ethanol extract, and solid-liquid ratio is 3g: 50ml; Under 27 DEG C of temperature conditions, carry out lixiviate operation; After extraction time 10h, obtain magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution;
The preparation technology of described Herba Saxifragae extracting solution comprises and Herba Saxifragae pulverized and crossed 50 mesh sieves, and to add concentration be 80% ethanol extract, solid-liquid ratio 1g: 25ml; Under 50 DEG C of temperature conditions, carry out ultrasonic extraction operation, hyperacoustic ultrasonic power is 100W; After extraction time 35min, obtain Herba Saxifragae extracting solution;
The preparation technology of described thorn Acanthopanan trifoliatus (L.) Merr. extracting solution comprises 50 mesh sieves are pulverized and crossed to thorn Acanthopanan trifoliatus (L.) Merr., and to add concentration be 80% ethanol extract, and solid-liquid ratio is 1g: 20ml; Carry out microwave extraction operation, microwave power is 200W; After extraction time 3min, obtain stinging Acanthopanan trifoliatus (L.) Merr. extracting solution.
Preferably, above-mentioned keratin essence also can have following features, and described plant antiseptic agent comprises:
Radix Et Rhizoma Rhei extract 40 weight portions;
Pericarpium Granati extracting solution 15 weight portions;
Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution 15 weight portions;
Herba Saxifragae extracting solution 20 weight portions;
Thorn Acanthopanan trifoliatus (L.) Merr. extracting solution 10 weight portions.
Preferably, above-mentioned keratin essence also can have following features, and described plant antiseptic agent comprises:
Radix Et Rhizoma Rhei extract 35 weight portions;
Pericarpium Granati extracting solution 10 weight portions;
Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution 15 weight portions;
Herba Saxifragae extracting solution 25 weight portions;
Thorn Acanthopanan trifoliatus (L.) Merr. extracting solution 15 weight portions.
Preferably, above-mentioned keratin essence also can have following features, and described plant antiseptic agent comprises:
Radix Et Rhizoma Rhei extract 30 weight portions;
Pericarpium Granati extracting solution 20 weight portions;
Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution 10 weight portions;
Herba Saxifragae extracting solution 30 weight portions;
Thorn Acanthopanan trifoliatus (L.) Merr. extracting solution 10 weight portions.
Preferably, above-mentioned keratin essence also can have following features, and described plant antiseptic agent comprises:
Radix Et Rhizoma Rhei extract 25 weight portions;
Pericarpium Granati extracting solution 25 weight portions;
Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution 25 weight portions;
Herba Saxifragae extracting solution 10 weight portions;
Thorn Acanthopanan trifoliatus (L.) Merr. extracting solution 15 weight portions.
Preferably, above-mentioned keratin essence also can have following features, and described plant antiseptic agent comprises:
Radix Et Rhizoma Rhei extract 20 weight portions;
Pericarpium Granati extracting solution 15 weight portions;
Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution 15 weight portions;
Herba Saxifragae extracting solution 35 weight portions;
Thorn Acanthopanan trifoliatus (L.) Merr. extracting solution 15 weight portions.
Technique scheme of the present invention has following beneficial effect:
The present invention has unique function and curative effect by the active ingredient of extracting in Chinese herbal medicine, and makes full use of their good bacteria resistance functions, prepares corresponding plant antiseptic agent and is applied in essence; Essence provided by the invention, by adding natural plants antiseptic, can effectively reduce the use amount of synthetic antiseptic, can effectively reduce the potential hazard that essence exists consumer.
Other features and advantages of the present invention will be set forth in the following description, and, partly from description, become apparent, or understand by implementing the present invention.Object of the present invention and other advantages can be realized and be obtained by specifically noted structure in description, claims.
Detailed description of the invention
For making the object, technical solutions and advantages of the present invention clearer, hereinafter will be elaborated to embodiments of the invention.It should be noted that, in the situation that not conflicting, the combination in any mutually of the feature in embodiment and embodiment in the application.
The invention provides a kind of biological activity micromolecule polypeptide keratin essence, comprise keratin, Glycyrrhiza glabra L., oat active peptide, glycerol, Parleam, glycerol stearic acid, half times of stearic acid of methyl glucoside, Jojoba seed oil and antiseptic, it is characterized in that; Described antiseptic is plant antiseptic agent,
Concrete, described plant antiseptic agent comprises: Radix Et Rhizoma Rhei extract 20-40 weight portion; Pericarpium Granati extracting solution 10-25 weight portion; Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution 10-25 weight portion; Herba Saxifragae extracting solution 10-35 weight portion; Thorn Acanthopanan trifoliatus (L.) Merr. extracting solution 10-15 weight portion.
Accordingly, in concrete operations of the present invention, the preparation technology of each extracting solution is as described below:
The preparation technology of described Radix Et Rhizoma Rhei extract comprises 100 mesh sieves are pulverized and crossed to Radix Et Rhizoma Rhei dry tablet, and to add concentration be 70% ethanol extraction agent, carries out the ultrasonic Treatment operation of 35min; Carry out the operation of constant temperature reflux, extract,, reflux temperature is 60 DEG C, and the time is 1h; Finally extracting liq is carried out obtaining Radix Et Rhizoma Rhei extract after vacuum filtration, distilling under reduced pressure concentration operation;
The preparation technology of described Pericarpium Granati extracting solution comprises and Pericarpium Granati pulverized and crossed 50 mesh sieves, and to add concentration be 60% ethanol extract, solid-liquid ratio 1g: 30ml; Under 35 DEG C of temperature conditions, after lixiviate, filter; After extraction time 7h, obtain filtrate, will after filtrate evaporation and concentration, obtain Pericarpium Granati extracting solution;
The preparation technology of described magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution comprises and magnolia officinalis rehd.et wils.var.biloba rehd.et wils. pulverized and crossed 50 mesh sieves, and to add concentration be 60% ethanol extract, and solid-liquid ratio is 3g: 50ml; Under 27 DEG C of temperature conditions, carry out lixiviate operation; After extraction time 10h, obtain magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution;
The preparation technology of described Herba Saxifragae extracting solution comprises and Herba Saxifragae pulverized and crossed 50 mesh sieves, and to add concentration be 80% ethanol extract, solid-liquid ratio 1g: 25ml; Under 50 DEG C of temperature conditions, carry out ultrasonic extraction operation, hyperacoustic ultrasonic power is 100W; After extraction time 35min, obtain Herba Saxifragae extracting solution;
The preparation technology of described thorn Acanthopanan trifoliatus (L.) Merr. extracting solution comprises 50 mesh sieves are pulverized and crossed to thorn Acanthopanan trifoliatus (L.) Merr., and to add concentration be 80% ethanol extract, and solid-liquid ratio is 1g: 20ml; Carry out microwave extraction operation, microwave power is 200W; After extraction time 3min, obtain stinging Acanthopanan trifoliatus (L.) Merr. extracting solution.
In order further to check the anti-microbial property of above-mentioned plant antiseptic agent provided by the invention, now carry out following corresponding experiment test by antibacterial test experimental technique conventional in prior art.
1, the anti-microbial property of plant antiseptic agent test;
Plant antiseptic agent: following several embodiment provided by the invention, in table 1;
Table 1: the content explanation (unit: weight portion) of embodiment 1-5
| Sequence number | Component | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 |
| Component 1 | Radix Et Rhizoma Rhei extract | 40 | 35 | 30 | 25 | 20 |
| Component 2 | Pericarpium Granati extracting solution | 15 | 10 | 20 | 25 | 15 |
| Component 3 | Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution | 15 | 15 | 10 | 25 | 15 |
| Component 4 | Herba Saxifragae extracting solution | 20 | 25 | 30 | 10 | 35 |
| Component 5 | Perverse Acanthopanan trifoliatus (L.) Merr. extracting solution | 10 | 15 | 10 | 15 | 15 |
Strain and condition of culture: in specific experiment of the present invention, adopt strain, in table 2;
Table 2: strain explanation
| Kind | Culture medium | Condition of culture |
| Staphylococcus aureus | Nutrient agar/PCA | 30℃/48h |
| Escherichia coli | Nutrient agar/PCA | 30℃/48h |
| Pseudomonas | False unit cell agar culture medium | 25℃/48h |
| The dead circumfili bacterium of heat | STAA agar culture medium, | 30℃/48h |
The summary of filter paper experimental procedure;
2 of the bacterium colonies that picking cultivation 24-48h is of moderate size, sterile working adds in 9m l physiological saline solution, uses magnetic stirrer 1min, and becoming is 3-5X10 containing bacterium colony uniformly
6-10
7cfu.mL
-1outstanding bacterium liquid for subsequent use; It is 6mm disk that the filter paper of thickness 1.5mm is broken into diameter, and by after filter paper parcel, 160 DEG C of dry heat sterilization 2h are for subsequent use; By the selective medium heating and melting for each confession examination bacterium preparing, be poured in too heat-killed culture dish, for subsequent use after flat board solidifies; Draw respectively 0.2mL respectively for trying bacteria suspension in plate with aseptic straw, carefully coating is even by bacteria suspension to be coated with rod by aseptic glass triangle; Filter paper is soaked to 1min respectively in plant antiseptic agent embodiment 1-5, take out cool micro-dry being gently affixed on flat board; Then plate is inverted in calorstat, each bacterium is cultivated 24h according to optimum temperature; Measure the diameter mm of each inhibition zone with micrometer; Bacteria used thereby suspension is down flat to plate numeration simultaneously.
Test data analysis; Plant antiseptic agent embodiment 1-5 experimental data is in table 3;
Table 3: embodiment 1-5 experimental data synopsis (mm of unit)
| Kind | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 |
| Staphylococcus aureus | 19.6 | 19.1 | 20.4 | 18.1 | 16.5 |
| Escherichia coli | 20.5 | 17.4 | 19.4 | 17.4 | 15.6 |
| Pseudomonas | 20.8 | 15.4 | 18.1 | 16.6 | 15.9 |
| The dead circumfili bacterium of heat | 18.1 | 17.1 | 18.6 | 16.2 | 14.4 |
| Blank group | 6.0 | 6.0 | 6.0 | 6.0 | 6.0 |
According to above-mentioned experimental data, can tentatively learn, in plant antiseptic agent embodiment 1-5 provided by the invention, anti-microbial property is embodiment 1 and embodiment 3 preferably.Further, now above-described embodiment 1, enforcement 3 are carried out to control comparison experiment with plant antiseptic agent of the prior art.Need explanation, during prior art control experiment is analyzed, prior art contrast 1, prior art contrast 2, the embodiment of the present application 1, the application implement 3 and all choose equal-volume and carry out corresponding control experiment.Wherein,
Embodiment 1-3 data show, can reach good bacteriostasis and sterilization effect by adding 0.01% Methylisothiazolinone antiseptic; Embodiment 4-6 data show, the addition of plant antiseptic agent embodiment 1 when above, can reach good bacteriostasis and sterilization effect 1.8%; Embodiment 7-9 data show, the addition of plant antiseptic agent embodiment 3 when above, can reach good bacteriostasis and sterilization effect 1.3%.Meanwhile, 4-9 data are known in conjunction with the embodiments: the antibacterial effect of plant antiseptic agent enforcement 3 in essence embodiment is better than the antibacterial effect of plant antiseptic agent embodiment 1 in essence embodiment.Drop in conjunction with entreprise cost, finally determine that the adding proportion of plant antiseptic agent embodiment 3 is 1.3%.That is, finally determine that plant antiseptic agent embodiment 3 is preferably plant antiseptic agent embodiment of effect, the essence embodiment 8 that contains this plant antiseptic agent embodiment 3 is the essence embodiment that antibacterial effect is better, input cost is lower and be suitable for marketing.
Above-mentioned plant antiseptic agent provided by the invention can be used as a kind of good essence, can there is good bacteriostasis to skin, hair products, life-time service safety, non-stimulated, free from extraneous odour, avirulence, without anaphylaxis, can not make the viscosity of product, pH value change, under pH value and temperature conditions, stablizing effectively widely, there is longer vigor, fungus and bacterium is had to the bactericidal effect of wide spectrum.The present invention has unique function and curative effect by the active ingredient of extracting in Chinese herbal medicine, and makes full use of their good bacteria resistance functions, prepares corresponding plant antiseptic agent and is applied in essence; Essence provided by the invention, by adding natural plants antiseptic, can effectively reduce the use amount of synthetic antiseptic, can effectively reduce the potential hazard that synthetic antiseptic exists consumer.
It should be noted that, the plant antiseptic agent adopting in above-mentioned essence provided by the invention can be applied in other cosmetics technical fields, in facial film, protective skin cream etc., all can realize good technique effect.
Although it is apparent to those skilled in the art that the disclosed embodiment of the present invention as above, the embodiment that described content only adopts for ease of understanding the present invention, not in order to limit the present invention.Those of skill in the art under any the present invention; do not departing under the prerequisite of the disclosed spirit and scope of the present invention; can in the form of implementing and details, carry out any amendment and variation; but scope of patent protection of the present invention, still must be as the criterion with the scope that appending claims was defined.
Claims (6)
1. a keratin essence, comprises keratin, Glycyrrhiza glabra L., oat active peptide, glycerol, Parleam, glycerol stearic acid, half times of stearic acid of methyl glucoside, Jojoba seed oil and antiseptic, it is characterized in that; Described antiseptic is plant antiseptic agent, and described plant antiseptic agent comprises:
Radix Et Rhizoma Rhei extract 20-40 weight portion;
Pericarpium Granati extracting solution 10-25 weight portion;
Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution 10-25 weight portion;
Herba Saxifragae extracting solution 10-35 weight portion;
Thorn Acanthopanan trifoliatus (L.) Merr. extracting solution 10-15 weight portion;
The preparation technology of described Radix Et Rhizoma Rhei extract comprises 100 mesh sieves are pulverized and crossed to Radix Et Rhizoma Rhei dry tablet, and to add concentration be 70% ethanol extraction agent, carries out the ultrasonic Treatment operation of 35min; Carry out the operation of constant temperature reflux, extract,, reflux temperature is 60 DEG C, and the time is 1h; Finally extracting liq is carried out obtaining Radix Et Rhizoma Rhei extract after vacuum filtration, distilling under reduced pressure concentration operation;
The preparation technology of described Pericarpium Granati extracting solution comprises and Pericarpium Granati pulverized and crossed 50 mesh sieves, and to add concentration be 60% ethanol extract, solid-liquid ratio 1g: 30ml; Under 35 DEG C of temperature conditions, after lixiviate, filter; After extraction time 7h, obtain filtrate, will after filtrate evaporation and concentration, obtain Pericarpium Granati extracting solution;
The preparation technology of described magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution comprises and magnolia officinalis rehd.et wils.var.biloba rehd.et wils. pulverized and crossed 50 mesh sieves, and to add concentration be 60% ethanol extract, and solid-liquid ratio is 3g: 50ml; Under 27 DEG C of temperature conditions, carry out lixiviate operation; After extraction time 10h, obtain magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution;
The preparation technology of described Herba Saxifragae extracting solution comprises and Herba Saxifragae pulverized and crossed 50 mesh sieves, and to add concentration be 80% ethanol extract, solid-liquid ratio 1g: 25ml; Under 50 DEG C of temperature conditions, carry out ultrasonic extraction operation, hyperacoustic ultrasonic power is 100W; After extraction time 35min, obtain Herba Saxifragae extracting solution;
The preparation technology of described thorn Acanthopanan trifoliatus (L.) Merr. extracting solution comprises 50 mesh sieves are pulverized and crossed to thorn Acanthopanan trifoliatus (L.) Merr., and to add concentration be 80% ethanol extract, and solid-liquid ratio is 1g: 20ml; Carry out microwave extraction operation, microwave power is 200W; After extraction time 3min, obtain stinging Acanthopanan trifoliatus (L.) Merr. extracting solution.
2. keratin essence according to claim 1, is characterized in that, described plant antiseptic agent comprises:
Radix Et Rhizoma Rhei extract 40 weight portions;
Pericarpium Granati extracting solution 15 weight portions;
Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution 15 weight portions;
Herba Saxifragae extracting solution 20 weight portions;
Thorn Acanthopanan trifoliatus (L.) Merr. extracting solution 10 weight portions.
3. keratin essence according to claim 1, is characterized in that, described plant antiseptic agent comprises:
Radix Et Rhizoma Rhei extract 35 weight portions;
Pericarpium Granati extracting solution 10 weight portions;
Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution 15 weight portions;
Herba Saxifragae extracting solution 25 weight portions;
Thorn Acanthopanan trifoliatus (L.) Merr. extracting solution 15 weight portions.
4. keratin essence according to claim 1, is characterized in that, described plant antiseptic agent comprises:
Radix Et Rhizoma Rhei extract 30 weight portions;
Pericarpium Granati extracting solution 20 weight portions;
Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution 10 weight portions;
Herba Saxifragae extracting solution 30 weight portions;
Thorn Acanthopanan trifoliatus (L.) Merr. extracting solution 10 weight portions.
5. keratin essence according to claim 1, is characterized in that, described plant antiseptic agent comprises:
Radix Et Rhizoma Rhei extract 25 weight portions;
Pericarpium Granati extracting solution 25 weight portions;
Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution 25 weight portions;
Herba Saxifragae extracting solution 10 weight portions;
Thorn Acanthopanan trifoliatus (L.) Merr. extracting solution 15 weight portions.
6. keratin essence according to claim 1, is characterized in that, described plant antiseptic agent comprises:
Radix Et Rhizoma Rhei extract 20 weight portions;
Pericarpium Granati extracting solution 15 weight portions;
Magnolia officinalis rehd.et wils.var.biloba rehd.et wils. extracting solution 15 weight portions;
Herba Saxifragae extracting solution 35 weight portions;
Thorn Acanthopanan trifoliatus (L.) Merr. extracting solution 15 weight portions.
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| CN201410280021.3A CN104055685B (en) | 2014-06-22 | 2014-06-22 | Bioactive micro-molecule polypeptide keratin essence |
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| CN201410280021.3A CN104055685B (en) | 2014-06-22 | 2014-06-22 | Bioactive micro-molecule polypeptide keratin essence |
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| CN104055685B CN104055685B (en) | 2015-07-15 |
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Cited By (7)
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| CN104382791A (en) * | 2014-11-26 | 2015-03-04 | 广州珂妃化妆品有限公司 | Aloe-extract containing bacterium inhibiting, itching relieving and healing promoting product and method for preparing same |
| CN105616263A (en) * | 2014-11-25 | 2016-06-01 | 杨榕 | Main formula of seeding watermelon moisture-retention mask |
| CN106309272A (en) * | 2016-08-24 | 2017-01-11 | 广东芭薇生物科技股份有限公司 | Whitening cream and preparing method thereof |
| CN106619438A (en) * | 2016-11-17 | 2017-05-10 | 东莞波顿香料有限公司 | Plant-derived antibacterial agent and liquid soap and toothpaste with plant-derived antibacterial agent |
| CN107028863A (en) * | 2017-03-22 | 2017-08-11 | 北海市宝珠林海洋科技有限公司 | A kind of hydrolyzed pearl facial mask liquid and preparation method thereof |
| CN107049800A (en) * | 2017-03-08 | 2017-08-18 | 张仕英 | A kind of preparation method of the nano-cellulose work(facial mask containing plant extraction liquid |
| CN114948785A (en) * | 2022-04-21 | 2022-08-30 | 山东仟草医药科技有限公司 | Compound small-molecule active peptide essence capable of astringing and relieving acne red and swollen and secondarily polishing |
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| CN102860961A (en) * | 2012-09-24 | 2013-01-09 | 彭再辉 | Eye pad essence containing peony root extracts and preparation method for eye pad essence |
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| CN102860961A (en) * | 2012-09-24 | 2013-01-09 | 彭再辉 | Eye pad essence containing peony root extracts and preparation method for eye pad essence |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105616263A (en) * | 2014-11-25 | 2016-06-01 | 杨榕 | Main formula of seeding watermelon moisture-retention mask |
| CN104382791A (en) * | 2014-11-26 | 2015-03-04 | 广州珂妃化妆品有限公司 | Aloe-extract containing bacterium inhibiting, itching relieving and healing promoting product and method for preparing same |
| CN106309272A (en) * | 2016-08-24 | 2017-01-11 | 广东芭薇生物科技股份有限公司 | Whitening cream and preparing method thereof |
| CN106619438A (en) * | 2016-11-17 | 2017-05-10 | 东莞波顿香料有限公司 | Plant-derived antibacterial agent and liquid soap and toothpaste with plant-derived antibacterial agent |
| CN106619438B (en) * | 2016-11-17 | 2020-04-21 | 东莞波顿香料有限公司 | Plant source bacteriostatic agent and hand sanitizer and toothpaste containing plant source bacteriostatic agent |
| CN107049800A (en) * | 2017-03-08 | 2017-08-18 | 张仕英 | A kind of preparation method of the nano-cellulose work(facial mask containing plant extraction liquid |
| CN107028863A (en) * | 2017-03-22 | 2017-08-11 | 北海市宝珠林海洋科技有限公司 | A kind of hydrolyzed pearl facial mask liquid and preparation method thereof |
| CN114948785A (en) * | 2022-04-21 | 2022-08-30 | 山东仟草医药科技有限公司 | Compound small-molecule active peptide essence capable of astringing and relieving acne red and swollen and secondarily polishing |
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| CN104055685B (en) | 2015-07-15 |
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