CN104053979B - 用于处理设置在基板上的生物样本的设备和自动方法 - Google Patents

用于处理设置在基板上的生物样本的设备和自动方法 Download PDF

Info

Publication number
CN104053979B
CN104053979B CN201280067151.8A CN201280067151A CN104053979B CN 104053979 B CN104053979 B CN 104053979B CN 201280067151 A CN201280067151 A CN 201280067151A CN 104053979 B CN104053979 B CN 104053979B
Authority
CN
China
Prior art keywords
substrate
reagent
substrates
processing
controller
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201280067151.8A
Other languages
English (en)
Chinese (zh)
Other versions
CN104053979A (zh
Inventor
马克·布赖恩·多克里尔
塞谬尔·加松
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leica Biosystems Melbourne Pty Ltd
Original Assignee
Leica Biosystems Melbourne Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leica Biosystems Melbourne Pty Ltd filed Critical Leica Biosystems Melbourne Pty Ltd
Publication of CN104053979A publication Critical patent/CN104053979A/zh
Application granted granted Critical
Publication of CN104053979B publication Critical patent/CN104053979B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31Apparatus therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31Apparatus therefor
    • G01N1/312Apparatus therefor for samples mounted on planar substrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00079Evaporation covers for slides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/0092Scheduling
    • G01N2035/0094Scheduling optimisation; experiment design

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201280067151.8A 2011-11-16 2012-11-15 用于处理设置在基板上的生物样本的设备和自动方法 Active CN104053979B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161560569P 2011-11-16 2011-11-16
US61/560,569 2011-11-16
PCT/AU2012/001415 WO2013071358A2 (en) 2011-11-16 2012-11-15 Biological sample treatment apparatus

Publications (2)

Publication Number Publication Date
CN104053979A CN104053979A (zh) 2014-09-17
CN104053979B true CN104053979B (zh) 2018-03-27

Family

ID=48430270

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280067151.8A Active CN104053979B (zh) 2011-11-16 2012-11-15 用于处理设置在基板上的生物样本的设备和自动方法

Country Status (6)

Country Link
US (3) US10036690B2 (https=)
EP (1) EP2780688B1 (https=)
JP (2) JP2014533824A (https=)
CN (1) CN104053979B (https=)
AU (1) AU2012339621B2 (https=)
WO (1) WO2013071358A2 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1208378B9 (en) * 1999-07-08 2014-12-10 Lee H. Angros Antigen recovery and/or staining apparatus and method
WO2016196210A2 (en) 2015-05-29 2016-12-08 Illumina, Inc. Sample carrier and assay system for conducting designated reactions
DE112016003593T5 (de) * 2015-08-06 2018-05-30 Elemental Scientific, Inc. Autosampler-Proben- und Probengestell-Identifizierung
JP6208301B1 (ja) * 2016-07-29 2017-10-04 シスメックス株式会社 標本搬送装置、塗抹標本システム及び塗抹標本作製装置
JP1593835S (https=) * 2017-05-31 2017-12-25
JP1593834S (https=) * 2017-05-31 2017-12-25
JP1593836S (https=) * 2017-05-31 2017-12-25
JP1593833S (https=) * 2017-05-31 2017-12-25
JP1593832S (https=) * 2017-05-31 2017-12-25
AU2019410098B2 (en) * 2018-12-20 2024-08-15 Leica Biosystems Melbourne Pty Ltd A slide tray assembly
US12380968B2 (en) * 2020-08-18 2025-08-05 International Business Machines Corporation Multiple chemical programs for an array of chemical reactors with a single array of reactants
CN114965463B (zh) 2022-04-22 2024-02-02 上海英医达医疗器械用品有限公司 显微镜自动检测系统及方法
CN117009236B (zh) * 2023-08-07 2024-02-06 苏州福斯特万电子科技有限公司 点胶机硬件配置方法、装置、设备及存储介质
CN121729506A (zh) 2023-08-30 2026-03-24 福斯分析股份公司 核酸的组合预处理和杂交
AU2024335309A1 (en) 2023-08-30 2026-03-19 Foss Analytical A/S Improved hybridization assay with stringency buffer dilution
WO2025105081A1 (ja) * 2023-11-13 2025-05-22 株式会社日立ハイテク 試料処理装置
WO2025178607A1 (en) 2024-02-19 2025-08-28 Leica Biosystems Richmond, Inc. Chromogenic multiplexing methods and systems
WO2025196504A1 (en) 2024-03-16 2025-09-25 Leica Biosystems Newcastle Ltd. Blue chromogens and methods of using same
US20250321232A1 (en) 2024-04-15 2025-10-16 Leica Biosystems Newcastle Ltd. Chromogenic multiplexing methods and systems for identifying a cancer of unknown primary origin

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387326B1 (en) * 1994-07-19 2002-05-14 Fisher Scientific Company L.L.C. Automated slide staining system and method thereof
CN1726275A (zh) * 2002-12-20 2006-01-25 达可斯通(丹麦)公司 组织样品自动染色方法和装置
US20070105187A1 (en) * 2005-10-11 2007-05-10 Cytyc Corporation Methods and materials for fixing cytological samples
US20100099133A1 (en) * 2008-10-22 2010-04-22 Leica Biosystems Nussloch Gmbh Method and apparatus for the treatment of specimens
US20110136135A1 (en) * 2009-12-09 2011-06-09 Larsen Soeren Damgaard Apparatus and method for processing biological samples

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2834761B2 (ja) * 1989-03-28 1998-12-14 株式会社千代田製作所 免疫反応染色装置
US5355439A (en) * 1991-08-05 1994-10-11 Bio Tek Instruments Method and apparatus for automated tissue assay
US6735531B2 (en) * 1996-10-07 2004-05-11 Lab Vision Corporation Method and apparatus for automatic tissue staining
US6183693B1 (en) * 1998-02-27 2001-02-06 Cytologix Corporation Random access slide stainer with independent slide heating regulation
US6495106B1 (en) * 1998-03-24 2002-12-17 Biogenex Laboratories Automated staining apparatus
US8298485B2 (en) * 1999-07-08 2012-10-30 Lee H. Angros In situ heat induced antigen recovery and staining apparatus and method
AU2001281179A1 (en) * 2000-08-11 2002-02-25 Incyte Genomics, Inc. Microarray alignment mechanism
DE10144042B4 (de) * 2001-09-07 2006-04-13 Leica Microsystems Nussloch Gmbh Bearbeitungsvorrichtung zum Färben und Eindecken von Objektträgern
DE10149345B4 (de) * 2001-10-06 2007-11-15 Leica Mikrosysteme Gmbh Vorrichtung zur schnellen Gewebepräparation für histologische Untersuchungen
US7468161B2 (en) * 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
US7584019B2 (en) * 2003-12-15 2009-09-01 Dako Denmark A/S Systems and methods for the automated pre-treatment and processing of biological samples
US7850912B2 (en) * 2003-05-14 2010-12-14 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
US20060073074A1 (en) * 2004-10-06 2006-04-06 Lars Winther Enhanced sample processing system and methods of biological slide processing
US20080235055A1 (en) * 2003-07-17 2008-09-25 Scott Mattingly Laboratory instrumentation information management and control network
US7744817B2 (en) * 2003-08-11 2010-06-29 Sakura Finetek U.S.A., Inc. Manifold assembly
US7767152B2 (en) 2003-08-11 2010-08-03 Sakura Finetek U.S.A., Inc. Reagent container and slide reaction retaining tray, and method of operation
CN1965223A (zh) * 2004-03-02 2007-05-16 丹麦达科有限公司 用于生物学着色仪的试剂传送系统、释放设备和容器
US7508583B2 (en) * 2005-09-14 2009-03-24 Cytyc Corporation Configurable cytological imaging system
NO20060555L (no) * 2006-02-02 2007-08-03 Torstein Ljungmann Apparat for utforelse av behandlingsoperasjoner i forbindelse med farging av vevsprover pa objektglass
US20070269347A1 (en) * 2006-05-18 2007-11-22 Stanchfield James E Microscope slide incubation and processing system
WO2008074073A1 (en) * 2006-12-18 2008-06-26 Leica Biosystems Melbourne Pty Ltd Device and method for tissue handling and embedding
US9116129B2 (en) * 2007-05-08 2015-08-25 Idexx Laboratories, Inc. Chemical analyzer
WO2009009419A2 (en) * 2007-07-10 2009-01-15 Ventana Medical Systems, Inc. Apparatus and method for biological sample processing
JP2009050968A (ja) 2007-08-28 2009-03-12 Nagasaki Prefecture 把持ロボット装置
ES2447875T3 (es) * 2007-10-02 2014-03-13 Theranos, Inc. Dispositivos modulares para punto de cuidados y usos de los mismos
AU2009260113B2 (en) * 2008-06-16 2016-03-03 Leica Biosystems Melbourne Pty Ltd Improvements in staining instruments and methods
JP2012514201A (ja) * 2008-12-30 2012-06-21 バイオパス・オートメーション・エル・エル・シー 組織病理学のために組織サンプルを処理するためのシステム及び方法
JP5210903B2 (ja) * 2009-01-30 2013-06-12 株式会社日立ハイテクノロジーズ 試料分析装置
JP5215224B2 (ja) * 2009-04-01 2013-06-19 株式会社東芝 自動分析装置
BR112012011181A2 (pt) 2009-11-13 2020-10-13 Ventana Medical Systems, Inc. ''estação de processsamento de peças corrediça automatizada e método de processamento de uma amostra''
JP5417351B2 (ja) * 2011-01-26 2014-02-12 株式会社日立ハイテクノロジーズ 検体搬送システムおよびその制御方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387326B1 (en) * 1994-07-19 2002-05-14 Fisher Scientific Company L.L.C. Automated slide staining system and method thereof
CN1726275A (zh) * 2002-12-20 2006-01-25 达可斯通(丹麦)公司 组织样品自动染色方法和装置
US20070105187A1 (en) * 2005-10-11 2007-05-10 Cytyc Corporation Methods and materials for fixing cytological samples
US20100099133A1 (en) * 2008-10-22 2010-04-22 Leica Biosystems Nussloch Gmbh Method and apparatus for the treatment of specimens
US20110136135A1 (en) * 2009-12-09 2011-06-09 Larsen Soeren Damgaard Apparatus and method for processing biological samples

Also Published As

Publication number Publication date
EP2780688A4 (en) 2015-03-04
US11060957B2 (en) 2021-07-13
JP6457125B2 (ja) 2019-01-23
WO2013071358A3 (en) 2013-07-18
US10036690B2 (en) 2018-07-31
US20210293670A1 (en) 2021-09-23
CN104053979A (zh) 2014-09-17
WO2013071358A2 (en) 2013-05-23
JP2014533824A (ja) 2014-12-15
AU2012339621B2 (en) 2016-02-18
US11940360B2 (en) 2024-03-26
US20140342358A1 (en) 2014-11-20
EP2780688A2 (en) 2014-09-24
EP2780688B1 (en) 2022-09-14
AU2012339621A1 (en) 2014-06-05
JP2018112552A (ja) 2018-07-19
US20180321118A1 (en) 2018-11-08

Similar Documents

Publication Publication Date Title
CN104053979B (zh) 用于处理设置在基板上的生物样本的设备和自动方法
US11815518B2 (en) Automated high volume slide processing system
US9395284B2 (en) Automated system and method of treating tissue samples on slides
US11249095B2 (en) Automated high volume slide processing system
AU2006203033A1 (en) Automated high volume slide processing system

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant