CN104048906A - 分选装置和分选方法 - Google Patents

分选装置和分选方法 Download PDF

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Publication number
CN104048906A
CN104048906A CN201410042154.7A CN201410042154A CN104048906A CN 104048906 A CN104048906 A CN 104048906A CN 201410042154 A CN201410042154 A CN 201410042154A CN 104048906 A CN104048906 A CN 104048906A
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CN
China
Prior art keywords
flow channel
particles
voltage signal
particle
runner
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Pending
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CN201410042154.7A
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English (en)
Chinese (zh)
Inventor
佐藤一雅
胜本洋一
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Sony Corp
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Sony Corp
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Publication of CN104048906A publication Critical patent/CN104048906A/zh
Pending legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/005—Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/02—Separators
    • B03C5/022—Non-uniform field separators
    • B03C5/026—Non-uniform field separators using open-gradient differential dielectric separation, i.e. using electrodes of special shapes for non-uniform field creation, e.g. Fluid Integrated Circuit [FIC]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1023—Microstructural devices for non-optical measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1028—Sorting particles

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201410042154.7A 2013-03-13 2014-01-28 分选装置和分选方法 Pending CN104048906A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013050316A JP5991236B2 (ja) 2013-03-13 2013-03-13 分取装置
JP2013-050316 2013-03-13

Publications (1)

Publication Number Publication Date
CN104048906A true CN104048906A (zh) 2014-09-17

Family

ID=51502028

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410042154.7A Pending CN104048906A (zh) 2013-03-13 2014-01-28 分选装置和分选方法

Country Status (3)

Country Link
US (1) US9555421B2 (enExample)
JP (1) JP5991236B2 (enExample)
CN (1) CN104048906A (enExample)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108007848A (zh) * 2016-10-27 2018-05-08 统创科技股份有限公司 生物分选系统及应用生物分选系统的生物分选方法
CN110302849A (zh) * 2019-05-31 2019-10-08 昆明理工大学 一种基于介电电泳原理分选液滴的微流控装置及方法
CN110506201A (zh) * 2017-02-10 2019-11-26 东曹株式会社 粒子检测装置和粒子检测方法
CN110577890A (zh) * 2018-06-11 2019-12-17 夏普株式会社 生物体粒子观察装置以及生物体粒子观察方法
CN110982777A (zh) * 2018-10-02 2020-04-10 吴宏伟 细胞分选方法及系统
US10668469B2 (en) 2016-04-22 2020-06-02 Techtron Technology Co., Ltd. Biological sorting apparatus and method thereof
CN112023991A (zh) * 2020-07-24 2020-12-04 中国科学院上海微系统与信息技术研究所 一种单细胞介电检测芯片
CN112334234A (zh) * 2018-07-04 2021-02-05 罗伯特·博世有限公司 用于介电泳地捕集微粒的装置
CN113498362A (zh) * 2019-02-27 2021-10-12 京瓷株式会社 粒子分离测量设备以及粒子分离测量装置
CN114345428A (zh) * 2021-12-20 2022-04-15 中国科学院上海微系统与信息技术研究所 一种分选单细胞的微流控芯片及检测方法

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6688089B2 (ja) * 2016-01-22 2020-04-28 日本光電工業株式会社 フローセルおよび粒子分析装置
JP6436955B2 (ja) * 2016-02-02 2018-12-12 国立研究開発法人科学技術振興機構 粒子分取装置及び粒子分取方法
KR102120926B1 (ko) 2016-07-18 2020-06-09 삼성전자주식회사 무선 송수신기 및 그 동작 방법
EP3558540A4 (en) 2017-04-23 2020-08-12 Hewlett-Packard Development Company, L.P. PARTICLE SEPARATION
US11364503B2 (en) 2017-07-17 2022-06-21 Hewlett-Packard Development Company, L.P. Dielectrophoresis separators with cell ejection devices
JP6871116B2 (ja) 2017-09-15 2021-05-12 株式会社東芝 セルソータ
JP7003640B2 (ja) * 2017-12-26 2022-01-20 東ソー株式会社 粒子検出装置及び粒子検出方法
JP2019148501A (ja) * 2018-02-27 2019-09-05 日本碍子株式会社 流体用センサ
JP6941840B2 (ja) * 2018-07-11 2021-09-29 シャープ株式会社 粒子分別装置
CN108940599B (zh) * 2018-08-01 2020-04-24 中国矿业大学 一种颗粒静电分选系统
EP3990285A4 (en) 2019-06-25 2023-04-19 Hewlett-Packard Development Company, L.P. Molded structures with channels
CN113717846B (zh) * 2020-05-26 2023-08-29 中国科学院青岛生物能源与过程研究所 一种基于介电确定性位移的细胞分选芯片、装置及方法

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
ATE261114T1 (de) * 2002-02-01 2004-03-15 Leister Process Tech Mikrofluidisches bauelement und verfahren für die sortierung von partikeln in einem fluid
WO2004055505A1 (en) * 2002-12-12 2004-07-01 Aura Biosystems Inc. Dielectrophoretic particle profiling system and method
JP2006510020A (ja) * 2002-12-12 2006-03-23 オーラ バイオシステムズ インコーポレイテッド 静電泳動粒子のプロファイリングシステム及び方法
WO2005099419A2 (en) * 2004-04-13 2005-10-27 President And Fellows Of Harvard College Manipulation and/or detection of biological samples or other objects
US7998328B2 (en) * 2005-06-27 2011-08-16 Cfd Research Corporation Method and apparatus for separating particles by dielectrophoresis
JP5604862B2 (ja) * 2009-01-09 2014-10-15 ソニー株式会社 流路デバイス、複素誘電率測定装置及び誘電サイトメトリー装置
JP4798290B2 (ja) * 2010-01-12 2011-10-19 ソニー株式会社 調光装置及び撮像装置
JP2011237201A (ja) * 2010-05-06 2011-11-24 Sony Corp 微小粒子分取装置、マイクロチップ及びマイクロチップモジュール
JP5732816B2 (ja) * 2010-10-29 2015-06-10 ソニー株式会社 細胞分取装置及び細胞分取チップ
JP5659698B2 (ja) * 2010-10-29 2015-01-28 ソニー株式会社 試料流入装置、試料流入チップ及び試料流入方法
JP6003020B2 (ja) * 2011-08-03 2016-10-05 ソニー株式会社 マイクロチップ及び微小粒子分析装置

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10668469B2 (en) 2016-04-22 2020-06-02 Techtron Technology Co., Ltd. Biological sorting apparatus and method thereof
CN108007848A (zh) * 2016-10-27 2018-05-08 统创科技股份有限公司 生物分选系统及应用生物分选系统的生物分选方法
CN110506201A (zh) * 2017-02-10 2019-11-26 东曹株式会社 粒子检测装置和粒子检测方法
CN110577890A (zh) * 2018-06-11 2019-12-17 夏普株式会社 生物体粒子观察装置以及生物体粒子观察方法
CN112334234A (zh) * 2018-07-04 2021-02-05 罗伯特·博世有限公司 用于介电泳地捕集微粒的装置
US11975340B2 (en) 2018-07-04 2024-05-07 Robert Bosch Gmbh Device for dielectrophoretic capture of particles
CN110982777A (zh) * 2018-10-02 2020-04-10 吴宏伟 细胞分选方法及系统
CN113498362A (zh) * 2019-02-27 2021-10-12 京瓷株式会社 粒子分离测量设备以及粒子分离测量装置
CN110302849B (zh) * 2019-05-31 2021-04-30 昆明理工大学 一种基于介电电泳原理分选液滴的微流控装置及方法
CN110302849A (zh) * 2019-05-31 2019-10-08 昆明理工大学 一种基于介电电泳原理分选液滴的微流控装置及方法
CN112023991A (zh) * 2020-07-24 2020-12-04 中国科学院上海微系统与信息技术研究所 一种单细胞介电检测芯片
CN114345428A (zh) * 2021-12-20 2022-04-15 中国科学院上海微系统与信息技术研究所 一种分选单细胞的微流控芯片及检测方法
CN114345428B (zh) * 2021-12-20 2023-03-07 中国科学院上海微系统与信息技术研究所 一种分选单细胞的微流控芯片及检测方法

Also Published As

Publication number Publication date
US20140262970A1 (en) 2014-09-18
JP2014178119A (ja) 2014-09-25
US9555421B2 (en) 2017-01-31
JP5991236B2 (ja) 2016-09-14

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Application publication date: 20140917