CN104039314B - 含有左旋西替利或其药用盐和孟鲁司特或其药用盐的用于口服给药的稳定的药物制剂 - Google Patents

含有左旋西替利或其药用盐和孟鲁司特或其药用盐的用于口服给药的稳定的药物制剂 Download PDF

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Publication number
CN104039314B
CN104039314B CN201380004854.0A CN201380004854A CN104039314B CN 104039314 B CN104039314 B CN 104039314B CN 201380004854 A CN201380004854 A CN 201380004854A CN 104039314 B CN104039314 B CN 104039314B
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montelukast
acid
levocetirizine
capsule
pharmaceutical
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CN104039314A (zh
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权宅灌
金东胡
金京洙
金用镒
朴宰贤
禹钟守
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Hanmi Pharmaceutical Co Ltd
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Hanmi Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
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    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

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  • Physiology (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN201380004854.0A 2012-01-06 2013-01-04 含有左旋西替利或其药用盐和孟鲁司特或其药用盐的用于口服给药的稳定的药物制剂 Active CN104039314B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020120001954A KR101418404B1 (ko) 2012-01-06 2012-01-06 레보세티리진 또는 이의 약학적으로 허용가능한 염 및 몬테루카스트 또는 이의 약학적으로 허용가능한 염을 함유하는 안정한 경구투여용 약학 제제
KR10-2012-0001954 2012-01-06
PCT/KR2013/000057 WO2013103262A1 (en) 2012-01-06 2013-01-04 Stable pharmaceutical formulation for oral administration comprising levocetirizine or a pharmaceutically acceptable salt thereof, and montelukast or a pharmaceutically acceptable salt thereof

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Publication Number Publication Date
CN104039314A CN104039314A (zh) 2014-09-10
CN104039314B true CN104039314B (zh) 2017-07-14

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US (1) US9486528B2 (cg-RX-API-DMAC7.html)
EP (1) EP2800558B1 (cg-RX-API-DMAC7.html)
JP (1) JP6163165B2 (cg-RX-API-DMAC7.html)
KR (1) KR101418404B1 (cg-RX-API-DMAC7.html)
CN (1) CN104039314B (cg-RX-API-DMAC7.html)
AR (1) AR089666A1 (cg-RX-API-DMAC7.html)
BR (1) BR112014016472B1 (cg-RX-API-DMAC7.html)
ES (1) ES2671428T3 (cg-RX-API-DMAC7.html)
JO (1) JO3388B1 (cg-RX-API-DMAC7.html)
MX (1) MX354073B (cg-RX-API-DMAC7.html)
PH (1) PH12014501545B1 (cg-RX-API-DMAC7.html)
PL (1) PL2800558T3 (cg-RX-API-DMAC7.html)
PT (1) PT2800558T (cg-RX-API-DMAC7.html)
RU (1) RU2614382C2 (cg-RX-API-DMAC7.html)
SG (1) SG11201403811VA (cg-RX-API-DMAC7.html)
SI (1) SI2800558T1 (cg-RX-API-DMAC7.html)
TR (1) TR201807978T4 (cg-RX-API-DMAC7.html)
TW (1) TWI565482B (cg-RX-API-DMAC7.html)
WO (1) WO2013103262A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201405756B (cg-RX-API-DMAC7.html)

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US9717684B2 (en) 2014-04-25 2017-08-01 R.P. Scherer Technologies, Llc Stable montelukast solution
KR101669556B1 (ko) * 2014-07-02 2016-10-28 한미약품 주식회사 몬테루카스트 또는 이의 약제학적으로 허용가능한 염의 경구투여용 액상제제
JP6575031B2 (ja) * 2014-07-28 2019-09-18 日本ケミファ株式会社 モンテルカストナトリウム製剤
RU2580303C1 (ru) * 2015-02-18 2016-04-10 Общество с ограниченной ответственностью "ПРОФИТ ФАРМ" Состав таблетированной формы лекарственного средства с действующим веществом пророксан
PL3222279T3 (pl) 2016-03-21 2022-05-09 Invest Bielany Spółka Z Ograniczoną Odpowiedzialnością Doustny preparat farmaceutyczny montelukastu i lewocetyryzyny oraz sposób jego wytwarzania
KR102481517B1 (ko) * 2021-08-30 2022-12-27 주식회사 클라시아 약제학적 제제
JP2024514989A (ja) * 2021-10-21 2024-04-03 ハン ファ ファーマ カンパニー、リミテッド モンテルカストまたはその薬学的に許容可能な塩、及びレボセチリジンまたはその薬学的に許容可能な塩を含有する、安定性が改善されたフィルムコーティング錠剤
KR20240045586A (ko) 2022-09-30 2024-04-08 주식회사 제뉴원사이언스 레보세티리진 또는 이의 약학적으로 허용가능한 염 및 몬테루카스트 또는 이의 약학적으로 허용가능한 염을 포함하는 안정성이 향상된 이층정 정제 및 그의 제조방법
KR20250005771A (ko) 2023-07-03 2025-01-10 경동제약 주식회사 레보세티리진 및 몬테루카스트를 포함하는 복합 조성물
KR20250081149A (ko) * 2023-11-29 2025-06-05 알리코제약(주) 안정성이 향상된 몬테루카스트 및 루파타딘 함유 조성물 및 이의 제조 방법

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