CN104027440B - Relieving cough and resolving phlegm buccal tablet and preparation method thereof - Google Patents
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Abstract
The invention discloses a kind of relieving cough and resolving phlegm buccal tablet and preparation method thereof, it is characterized in that: Folium Eriobotryae 20-30 part, Pericarpium Citri Reticulatae 20-30 part, Fructus Phyllanthi 10-15 part, Flos Lonicerae 10-15 part, dark plum 10-15 part, wine cake wood 5-8 part.It has cough-relieving, reduces phlegm, detumescence, removing toxic substances, analgesia, the effect of eliminating the phlegm, and have no side effect, healing time is short, to human therapy cough, laryngopharynx swelling and pain, laryngalgia, particularly to cough and expectoration, laryngopharynx swelling and pain has significant curative effect.
Description
Technical field
The present invention relates to Chinese herbal medicine preparation technology field, be specially a kind of relieving cough and resolving phlegm buccal tablet and preparation method thereof.
Background technology
The diseases such as common flu, bronchitis, pneumonia, pharyngitis and asthma all can cause the ill symptomses such as cough, expectoration, asthma, laryngopharynx swelling and pain, doctor trained in Western medicine mainly adopts antiinflammatory clinically, antibiosis is then adopted usually to treat during aggravation, but adopt the western medical treatment potential that effective exciting human is not disease-resistant, make to ask for great treatment only minor illness, obstinate, spends huge and unsatisfactory curative effect easily, increases the financial burden of patient on foot.
Traditional Chinese medical science medical science is of long standing and well established, and modern Chinese medicine adopts traditional Chinese herbal medicine to treat this type of disease, can reach effect for the treatment of both the principal and secondary aspects of a disease.The traditional Chinese medical science is thought that this type of disease is many and is caused YANG QI deficiency because suffering from a deficiency of the kidney, body resistance against diseases is declined, cause cold invade human body and must not dissolve, causing cold virus and toxin thereof in body eventually can not effectively remove, and causes respiratory system not smooth and causes the diseases such as cough, asthma, laryngopharynx swelling and pain.
At present, the Chinese medicine of market being treated the diseases such as cough, expectoration is also more, and as loquat leaf extract, Radix Glycyrrhizae tabellae, cough syrup etc., its therapeutic effect is also affirmative.But treatment cycle is long, relieving cough and resolving phlegm effect is slow, and patient has the demand for the treatment of as early as possible usually ill, to remove ailing, recovers normal work and life.Therefore, develop a kind of fast and effectively, low cost, have cough-relieving, reduce phlegm, detumescence, removing toxic substances, analgesia, the relieving cough and resolving phlegm buccal tablet of the effect of eliminating the phlegm is just necessary.
Summary of the invention
The object of the invention is not enough for above-mentioned prior art and propose a kind of fast and effectively, low cost, there is cough-relieving, reduce phlegm, detumescence, removing toxic substances, analgesia, the effect of eliminating the phlegm, has no side effect, healing time is short, to human therapy cough, laryngopharynx swelling and pain, laryngalgia, particularly to cough and expectoration, laryngopharynx swelling and pain treatment relieving cough and resolving phlegm buccal tablet having significant curative effect and preparation method thereof.
The present invention realizes by the following technical solutions:
Relieving cough and resolving phlegm buccal tablet of the present invention, be made up of the raw material of following parts by weight:
Folium Eriobotryae 20-30 part, Pericarpium Citri Reticulatae 20-30 part, Fructus Phyllanthi 10-15 part, Flos Lonicerae 10-15 part, dark plum 10-15 part, wine cake wood 5-8 part.
Above-described relieving cough and resolving phlegm buccal tablet, is characterized in that: be made up of the raw material of following parts by weight: Folium Eriobotryae 25-28 part, Pericarpium Citri Reticulatae 25-28 part, Fructus Phyllanthi 12-15 part, Flos Lonicerae 12-15 part, Armeniaca mume Sieb. 12-15 part, wine cake wood 6-8 part.
The present invention is made up of Chinese medicinal materials such as Folium Eriobotryae, Pericarpium Citri Reticulatae, Fructus Phyllanthi, Flos Lonicerae, dark plum, wine cake wood, has cough-relieving, reduces phlegm, detumescence, removing toxic substances, analgesia, the effect of eliminating the phlegm, thus to human therapy cough, laryngopharynx swelling and pain, laryngalgia, particularly to cough and expectoration, laryngopharynx swelling and pain has significant curative effect.
Each medicine active ingredient of above-described relieving cough and resolving phlegm buccal tablet is analyzed:
Folium Eriobotryae, [another name] rake leaf, Ba Ye, Lu Juye; [English name] LoquatLeaf[Latin] EriobotryajaponicaThunb; The leaf of rosaceous plant Folium Eriobotryae; Flavor efficacy: bitter, acrid, cold, nontoxic; Clearing away lung-heat to relieve cough, regulating the stomach and sending down the abnormal ascending QI, quenches the thirst, lung-heat phlegmatic cough; Deficiency of YIN chronic cough; Hemoptysis; Epistaxis; Gastric heat is vomitted the sound of vomiting.1. " book on Chinese herbal medicine is new again ": lung heat clearing gas, fall lung-fire, relieving cough and resolving phlegm, emesis blood is choked blood, controls carbuncle flaccidity pyretic toxicity.2. Compendium of Material Medica: Folium Eriobotryae, controls the disease of lung stomach, mostly gets the merit ear of its therapeutic method to keep the adverse QI flowing downwards.3. " book on Chinese herbal medicine converges and says ": Folium Eriobotryae, peace gastric qi, profit cardiopulmonary, the medicine of nourishing the liver and kidney also.
Pericarpium Citri Reticulatae, [another name] Pericarpium Citri tangerinae, expensive old, Folium Styracis Suberifoliae, Fructus Citri tangerinae skin, extensively Pericarpium Citri tangerinae, Pericarpium Citri tangerinae, Citrus chachiensis Hort. C. Suavissima Tanaka, Pericarpium citri reticuatae chachiensis; [English name] CitrusreticulataBlanco.[Latin] PericarpiumCitriReticulatae, the young fruit of rutaceae orange and variety thereof or the peel of immature fruit; [nature and flavor] 1. " Chinese Pharmacopoeia " gas are fragrant, acrid in the mouth, hardship; [function cures mainly] regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, the distension and fullness in the abdomen of stagnation of QI in spleen and stomach or pain, dyspepsia.1. " medicine origin ": Pericarpium Citri tangerinae energy QI invigorating, adds Pericarpium Citri Reticulatae Viride and reduce by half, and removes stagnant gas, pushes away Chen Zhixin.2. " daily book on Chinese herbal medicine ": Pericarpium Citri tangerinae, can fall apart and can rush down, can temperature can mend, can disappear diaphragm gas, and reduce phlegm saliva, and spleen antitussive, logical five types of stranguria.3. " medicine origin ": go cold-evil in the heart, broken stagnant gas, strengthening the spleen stomach.
Fructus Phyllanthi, [another name] emblic leafflower fruit, meter Han, prestige fruit, wooden ripple, seven examine sorrow happiness, Lu public fat, Phyllanthus emblica L.; [Latin] Phyllanthusemblica; Euphorbiaceae, is born in height above sea level 200-2300 rice mountain region sparse woods, shrubbery, wasteland or gully area without shade.The ground such as distribution Jiangxi, Fujian, Guangdong, Hainan, Guangxi, Sichuan.[nature and flavor] are sweet, micro-puckery, cool.1. " Chinese Pharmacopoeia "--really: clearing away heat and cooling blood, promoting digestion and invigorating the stomach, cough-relieving of promoting the production of body fluid.2. " national Chinese herbal medicine compilation " root: for hypertension, stomachache, enteritis, tuberculous lymphadenitis.[function cures mainly] heat in blood blood stasis, dyspepsia, abdominal distention, cough, laryngalgia, xerostomia and vitamin C deficiency.
Flos Lonicerae, [another name] Flos Lonicerae, little egret flower, Flos Lonicerae, Flos Lonicerae, Flos Lonicerae, golden rattan, two bud flower, JINHUA, two precious flowers; Come from Compendium of Material Medica, [English
name]flosLonicerae[Latin] LonicerajaponicaThunb. shrub, Caprifoliaceae; Flavor efficacy: cold in nature, sweet in the mouth.There is heat-clearing and toxic substances removing, wind-heat dissipating, antiinflammatory, tonify deficiency treat effect of wind, cure mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.Effect: 1, resisting pathogenic microbes: experiment in vitro shows, flower and rattan to various pathogens as staphylococcus aureus, Hemolytic streptococcus, escherichia coli, dysentery bacterium, vibrio cholera, Bacillus typhi, Salmonella paratyphi etc. all have certain inhibitory action, also effective to streptococcus pneumoniae, meningococcus, bacillus pyocyaneus, tubercule bacillus.2, booster immunization function: Flos Lonicerae decoct is diluted to the concentration of 1:1280, still can promote leukocytic phagocytic function.
Armeniaca mume Sieb., [another name] dark plum, Fructus Armeniacae Mume; [Latin] VaticamangachapoiBlanco Dipterocarpaceae; Flavor efficacy: Gan Ping, " legendary god of farming's book on Chinese herbal medicine " definiteness sweet in the mouth is put down, can be entered liver, spleen, lung, large intestine, have the convergence effect of promoting the production of body fluid.The people trusted subordinate cold type of pain of suitable cold syndrome of the stomach, borborygmus diarrhoea person, poor appetite, anorexia, or the people stopping dyspepsia eats.Compendium of Material Medica: " in warm, ward off communicable subtropical diseases bad odor, control trusted subordinate's cold type of pain, cold-damp cholera.", " book on Chinese herbal medicine converges and says ": " control and stop dyspepsia, all cards of all excessive cold invading middle-JIAO(the spleen and stomach)." there is the therapeutic method to keep the adverse QI flowing downwards, feel at ease, cough-relieving antitussive, pain relieving stop typhoid fever dysphoria with smothery sensation, only cold and hot dysentery, effect of subduing swelling and detoxicating.
Wine cake wood, [another name] wild husky Citrus chachiensis Hort., meal soup wood, wine cake wood (" register planted by Guangxi medicine "), mountain Phyllanthus emblica L., mountain Fructus Citri tangerinae (" conventional Chinese herbal medicine color atlas "), Radix Glycosmidis Citrifoliae, Chinese lime, false Fructus Fortunellae Margaritae, water remaining piece; [English name] RootofCitrusleafGlycosmis[Latin]
glycosmiscitrifloia (Willd) Lindl.bald clean shrub, Rutaceae; [nature and flavor] are " conventional Chinese herbal medicine color atlas " 1.: root: pungent, temperature; Leaf: micro-sweet, temperature.2. " Guangxi Chinese herbal medicine ": micro-arduous, flat.[function cures mainly] expelling pathogenic wind from the body surface, reduces phlegm, cough-relieving, removing food stagnancy, dissipating blood stasis.Cure cold cough, abdominal pain due to retention of food, colicky.1. " register planted by Guangxi medicine ": root: analgesia preventing or arresting vomiting, dispelling the wind and dampness pathogens, cough.2. " conventional Chinese herbal medicine color atlas ": dispel the wind and deliver, circulation of qi promoting cough-relieving.Cure cold cough, hernia pain due to disorder of QI, chilblain.3. " Guangxi Chinese herbal medicine ": eliminate the phlegm, dissipating blood stasis, removing food stagnancy.Control abdominal pain due to retention of food, treating swelling and pain by traumatic injury.
Above-described relieving cough and resolving phlegm buccal tablet is tentatively on probation in clinical treatment cough, laryngopharynx swelling and pain project, and reflection is good, without obvious toxic-side effects.
The preparation method of relieving cough and resolving phlegm buccal tablet of the present invention made by above-mentioned each component medicine:
(1) by weight the Folium Eriobotryae of drying, Pericarpium Citri Reticulatae, Fructus Phyllanthi, Flos Lonicerae, Armeniaca mume Sieb. and wine cake wood are broken into lOO-120 object fine powder; Medicated powder is poured in pithos and soak 40 minutes, add 8-10 times that the water yield is medicine gross weight, boil 1-2 hour, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(2) medicinal residues after filtration in step 1 are added 3-5 times that the water yield is medicine gross weight, boil 0.5-1 hour, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(3) extracting solution mixing step 1 and step 2 obtained, is condensed into thick paste, adds wet and slippery dose of mix homogeneously and make soft material;
(4) soft material is crossed 18 orders, then dry under 50-60 DEG C of condition, gained granule carries out tabletting, obtained Traditional Chinese medicine lozenge.
Above-described wet and slippery dose is one or more in stearate, Pulvis Talci, hydride vegetable oil, Polyethylene Glycol.
Above-mentioned Chinese medicine of the present invention, according to different situations and pharmaceutical factory condition, can also make other preparation.Buccal tablet of the present invention also can coordinate other medicament Clinical practice,
the invention has the beneficial effects as follows:
1, the present invention plays cough-relieving, reduces phlegm, detumescence, removing toxic substances, and analgesia, the effect of eliminating the phlegm, has significant curative effect to human therapy cough, laryngopharynx swelling and pain, laryngalgia, particularly right cough and expectoration, laryngopharynx swelling and pain.
2, use all can be fully recovered for 3-5 of the present invention days, and cure rate is more than 80%, and effective percentage is more than 90%, and to human non-toxic's side effect, easy to use, cost is low.
Detailed description of the invention
Embodiment 1:
(1) by weight the Folium Eriobotryae 30 parts of drying, Pericarpium Citri Reticulatae 30 parts, Fructus Phyllanthi 15 parts, Flos Lonicerae 15 parts, 15 parts, Armeniaca mume Sieb. and 8 parts, wine cake wood are broken into 120 object fine powders; Medicated powder is poured in pithos and soak 40 minutes, add 10 times that the water yield is medicine gross weight, boil 2 hours, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(2) medicinal residues after filtration in step 1 are added 5 times that the water yield is medicine gross weight, boil 1 hour, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(3) extracting solution mixing step 1 and step 2 obtained, is condensed into thick paste, adds Polyethylene Glycol mix homogeneously and make soft material;
(4) soft material is crossed 18 orders, then dry under 60 DEG C of conditions, gained granule carries out tabletting, obtained Traditional Chinese medicine lozenge.
Embodiment 2:
(1) by weight the Folium Eriobotryae 28 parts of drying, Pericarpium Citri Reticulatae 28 parts, Fructus Phyllanthi 14 parts, Flos Lonicerae 14 parts, 14 parts, Armeniaca mume Sieb. and 7 parts, wine cake wood are broken into 120 object fine powders; Medicated powder is poured in pithos and soak 40 minutes, add 10 times that the water yield is medicine gross weight, boil 1.5 hours, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(2) medicinal residues after filtration in step 1 are added 5 times that the water yield is medicine gross weight, boil 0.8 hour, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(3) extracting solution mixing step 1 and step 2 obtained, is condensed into thick paste, adds hydride vegetable oil mix homogeneously and make soft material;
(4) soft material is crossed 18 orders, then dry under 58 DEG C of conditions, gained granule carries out tabletting, obtained Traditional Chinese medicine lozenge.
Embodiment 3:
(1) by weight the Folium Eriobotryae 22 parts of drying, Pericarpium Citri Reticulatae 22 parts, Fructus Phyllanthi 12 parts, Flos Lonicerae 12 parts, 12 parts, Armeniaca mume Sieb. and 7 parts, wine cake wood are broken into 110 object fine powders; Medicated powder is poured in pithos and soak 40 minutes, add 9 times that the water yield is medicine gross weight, boil 1 hour, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(2) medicinal residues after filtration in step 1 are added 4 times that the water yield is medicine gross weight, boil 0.5 hour, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(3) extracting solution mixing step 1 and step 2 obtained, is condensed into thick paste, adds stearate mix homogeneously and make soft material;
(4) soft material is crossed 18 orders, then dry under 55 DEG C of conditions, gained granule carries out tabletting, obtained Traditional Chinese medicine lozenge.
Embodiment 4:
(1) by weight the Folium Eriobotryae 20 parts of drying, Pericarpium Citri Reticulatae 20 parts, Fructus Phyllanthi 10 parts, Flos Lonicerae 10 parts, 10 parts, Armeniaca mume Sieb. and 6 parts, wine cake wood are broken into l00 object fine powder; Medicated powder is poured in pithos and soak 40 minutes, add 8 times that the water yield is medicine gross weight, boil 1 hour, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(2) medicinal residues after filtration in step 1 are added 3 times that the water yield is medicine gross weight, boil 0.5 hour, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(3) extracting solution mixing step 1 and step 2 obtained, is condensed into thick paste, adds stearate and Pulvis Talci mix homogeneously makes soft material;
(4) soft material is crossed 18 orders, then dry under 50 DEG C of conditions, gained granule carries out tabletting, obtained Traditional Chinese medicine lozenge.
clinical therapeutic efficacy:
In order to show that medicine of the present invention is to cough and expectoration, laryngopharynx swelling and pain therapeutic effect, has carried out following clinical experiment, since 2011, treat cough and expectoration patient 158 example altogether, cure and reach 136 person-times, transfer well 15 person-times to, invalid is 7 people, and cure rate can reach 86.1%, and effective percentage can reach 95.5%; Treatment laryngopharynx swelling and pain patient 136 example, cure and reach 113 person-times, effectively can reach 14 person-times, invalid is 9 person-times, and cure rate is 83.1%, and it is 84.7% that effective percentage can reach 93.3% its total cure rate, and total effective rate is 94.6%.
Practice according to traditional Chinese medical science pharmacology and clinical treatment can draw: relieving cough and resolving phlegm buccal tablet has significant effect to disease such as treatment cough and expectoration, laryngopharynx swelling and pain etc., can be widely used in clinical treatment and use.
Model case:
Case 1: Chen, man, 48 years old, people from Guigang, Guangxi, suffered from influenza with cough, abundant expectoration, taking and be not still clearly better after Western medicine for many days, through taking relieving cough and resolving phlegm buccal tablet of the present invention remission after 2 days, fully recovering after taking 5 days.
Case 2: not so-and-so, female, 4 years old, Guigang, Guangxi province, suffered from an inflammation of the lungs, and at pediatric transfusion and Comprehensive Treatment, still have the symptoms such as cough, abundant expectoration, take buccal tablet of the present invention second day, cough alleviates, and expectorant is few, after 5 days infant recovery from illness.
Case 3: Zhang, man, 46 years old, Mu Gen people from town, Guigang, Guangxi, was engaged in teaching job, because job specification needs to attend class continuously on dais, the frequent laryngopharynx swelling and pain of Mr. Zhang, all take the buccal tablet for the treatment of laryngopharynx swelling and pain, but effect is slow at every turn, treatment time is long, just can fully recover after 3 days through having taken relieving cough and resolving phlegm buccal tablet of the present invention.
Case 4: Zhao so-and-so, man, 28 years old, ocean town, Guigang, Guangxi main road ridge people from village, causes cough and expectoration because suffering from upper respiratory tract infection, within several days, is clearly better for seeing at hospital transfusion, through taken relieving cough and resolving phlegm buccal tablet of the present invention after 3 days symptom alleviate, after 7 days, cough and expectoration is just fully recovered.
Case 5: Zhu, man, 53 years old, Tantang District, Guigang, Guangxi Qin Tang people from town, because of suffer from bronchitis cause cough and expectoration, within several days, be clearly better for seeing at hospital transfusion, through taken relieving cough and resolving phlegm buccal tablet of the present invention after 2 days symptom alleviate, namely good after 5 days.
Claims (3)
1. a preparation method for relieving cough and resolving phlegm buccal tablet, is characterized in that, concrete preparation method is as follows:
(1) by weight the Folium Eriobotryae of drying, Pericarpium Citri Reticulatae, Fructus Phyllanthi, Flos Lonicerae, Armeniaca mume Sieb. and wine cake wood are broken into 100-120 object fine powder; Medicated powder is poured in pithos and soak 40 minutes, add 8-10 times that the water yield is medicine gross weight, boil 1-2 hour, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(2) medicinal residues after filtration in step 1 are added 3-5 times that the water yield is medicine gross weight, boil 0.5-1 hour, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(3) extracting solution mixing step 1 and step 2 obtained, is condensed into thick paste, adds wet and slippery dose of mix homogeneously and make soft material;
(4) soft material is crossed 18 orders, then dry under 50-60 DEG C of condition, gained granule carries out tabletting, obtained Traditional Chinese medicine lozenge; The parts by weight of above-mentioned raw materials are as follows:
Folium Eriobotryae 20-30 part, Pericarpium Citri Reticulatae 20-30 part, Fructus Phyllanthi 10-15 part, Flos Lonicerae 10-15 part, Armeniaca mume Sieb. 10-15 part, wine cake wood 5-8 part.
2. the preparation method of relieving cough and resolving phlegm buccal tablet according to claim 1, it is characterized in that, its preparation method is as follows:
(1) by weight the Folium Eriobotryae of drying, Pericarpium Citri Reticulatae, Fructus Phyllanthi, Flos Lonicerae, Armeniaca mume Sieb. and wine cake wood are broken into 100-120 object fine powder; Medicated powder is poured in pithos and soak 40 minutes, add 8-10 times that the water yield is medicine gross weight, boil 1-2 hour, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(2) medicinal residues after filtration in step 1 are added 3-5 times that the water yield is medicine gross weight, boil 0.5-1 hour, when fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(3) extracting solution mixing step 1 and step 2 obtained, is condensed into thick paste, adds wet and slippery dose of mix homogeneously and make soft material;
(4) soft material is crossed 18 orders, then dry under 50-60 DEG C of condition, gained granule carries out tabletting, obtained Traditional Chinese medicine lozenge; The parts by weight of above-mentioned raw materials are as follows:
Folium Eriobotryae 25-28 part, Pericarpium Citri Reticulatae 25-28 part, Fructus Phyllanthi 12-15 part, Flos Lonicerae 12-15 part, Armeniaca mume Sieb. 12-15 part, wine cake wood 6-8 part.
3. the preparation method of relieving cough and resolving phlegm buccal tablet according to claim 1 and 2, is characterized in that: described wet and slippery dose be stearate, Pulvis Talci, hydrogenated vegetable oil, one or more in Polyethylene Glycol.
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| CN105380275A (en) * | 2015-10-27 | 2016-03-09 | 全椒井府富硒生态牧业有限公司 | Selenium-rich emblic leafflower lozenge and preparing method thereof |
| CN110327420B (en) * | 2019-07-24 | 2021-04-23 | 广州中医药大学第一附属医院 | Buccal plum and preparation method thereof |
| CN116492437B (en) * | 2023-03-24 | 2023-12-12 | 云南贝泰妮生物科技集团股份有限公司 | Plant buccal tablet for improving respiratory tract immunity and preparation process thereof |
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