CN104027440A - Cough-relieving and phlegm-resolving lozenge and preparation method thereof - Google Patents
Cough-relieving and phlegm-resolving lozenge and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a cough-relieving and phlegm-resolving lozenge and a preparation method thereof. The lozenge is characterized by comprising 20 to 30 parts of loquat leaf, 20 to 30 parts of dried orange peel, 10 to 15 parts of emblic leafflower fruit, 10 to 15 parts of honeysuckle flower, 10 to 15 parts of smoked plum and 5 to 8 parts of root of citrusleaf Glycosmis. The lozenge has the advantages of cough-relieving, phlegm-reducing, detumescent, detoxifying, pain-easing and phlegm-eliminating effects, no toxic and side effects, short curing time and substantial curative effects on cough, a swollen sore throat and laryngalgia of people, especially on cough and expectoration and the swollen sore throat.
Description
Technical field
The present invention relates to Chinese herbal and crude drugs preparations technical field, be specially a kind of relieving cough and resolving phlegm buccal tablet and preparation method thereof.
Background technology
The diseases such as common flu, bronchitis, pneumonia, pharyngitis and asthma all can cause the ill symptomses such as cough, expectoration, asthma, laryngopharynx swelling and pain, doctor trained in Western medicine mainly adopts antiinflammatory clinically, when aggravation, adopt antibiosis usually to treat, but adopt western medical treatment not have the disease-resistant potential of effective exciting human, make to ask for great treatment only minor illness, obstinate, spends huge and unsatisfactory curative effect easily, increases on foot patient's financial burden.
Traditional Chinese medical science medical science is of long standing and well established, and modern Chinese medicine adopts traditional Chinese herbal medicine to treat this type of disease, can reach effect for the treatment of both the principal and secondary aspects of a disease.The traditional Chinese medical science thinks how this type of disease causes YANG QI deficiency because suffering from a deficiency of the kidney, body resistance against diseases is declined, cause cold invade human body and must not dissolve, causing eventually the interior cold virus of body and toxin thereof can not effectively remove, and causes respiratory system freely not cause the diseases such as cough, asthma, laryngopharynx swelling and pain.
At present, the Chinese medicine for the treatment of the diseases such as cough, expectoration on market is also more, and as loquat leaf extract, Radix Glycyrrhizae tabellae, cough syrup etc., its therapeutic effect is also sure.But treatment cycle is long, relieving cough and resolving phlegm effect is slow, and patient has the demand for the treatment of as early as possible conventionally ill, to remove slight illness, recovers normal work and life.Therefore, development one fast and effectively, cheaply, has cough-relieving, reduces phlegm, detumescence, and removing toxic substances, analgesia, the relieving cough and resolving phlegm buccal tablet of the effect of eliminating the phlegm is just necessary.
Summary of the invention
The object of the invention is for above-mentioned prior art not enough and propose one fast and effectively, cheaply, there is cough-relieving, reduce phlegm, detumescence, removing toxic substances, analgesia, the effect of eliminating the phlegm, has no side effect, healing time is short, to human therapy cough, laryngopharynx swelling and pain, laryngalgia, particularly, to cough and expectoration, laryngopharynx swelling and pain has treatment relieving cough and resolving phlegm buccal tablet of significant curative effect and preparation method thereof.
The present invention realizes by the following technical solutions:
Relieving cough and resolving phlegm buccal tablet of the present invention, made by the raw material of following parts by weight:
Folium Eriobotryae 20-30 part, Pericarpium Citri Reticulatae 20-30 part, Fructus Phyllanthi 10-15 part, Flos Lonicerae 10-15 part, dark plum 10-15 part, wine cake wood 5-8 part.
Above-described relieving cough and resolving phlegm buccal tablet, is characterized in that: the raw material by following parts by weight is made: Folium Eriobotryae 25-28 part, Pericarpium Citri Reticulatae 25-28 part, Fructus Phyllanthi 12-15 part, Flos Lonicerae 12-15 part, Armeniaca mume Sieb. 12-15 part, wine cake wood 6-8 part.
The present invention is made up of Chinese medicinal materials such as Folium Eriobotryae, Pericarpium Citri Reticulatae, Fructus Phyllanthi, Flos Lonicerae, dark plum, wine cake wood, has cough-relieving, reduces phlegm, detumescence, removing toxic substances, analgesia, the effect of eliminating the phlegm, thereby to human therapy cough, laryngopharynx swelling and pain, laryngalgia, particularly to cough and expectoration, laryngopharynx swelling and pain has significant curative effect.
Each medicine active ingredient of above-described relieving cough and resolving phlegm buccal tablet is analyzed:
Folium Eriobotryae, [another name] rake leaf, Ba Ye, Lu Juye; [English name] Loquat Leaf[Latin] Eriobotrya japonica Thunb; The leaf of rosaceous plant Folium Eriobotryae; Flavor efficacy: bitter, acrid, cold, nontoxic; Clearing away lung-heat to relieve cough, regulating the stomach and sending down the abnormal ascending QI, quenches the thirst, lung-heat phlegmatic cough; Deficiency of YIN chronic cough; Hemoptysis; Epistaxis; The gastric heat sound of vomiting of vomitting.1. " book on Chinese herbal medicine is new again ": lung heat clearing gas, lung-fire falls, relieving cough and resolving phlegm, the emesis blood blood of choking, controls carbuncle flaccidity pyretic toxicity.2. Compendium of Material Medica: Folium Eriobotryae, control the disease of lung stomach, mostly get the merit ear of its therapeutic method to keep the adverse QI flowing downwards.3. " book on Chinese herbal medicine converges and says ": Folium Eriobotryae, peace gastric qi, profit cardiopulmonary, the medicine of nourishing the liver and kidney is also.
Pericarpium Citri Reticulatae, [another name] Pericarpium Citri tangerinae, expensive old, Folium Styracis Suberifoliae, Fructus Citri tangerinae skin, wide Pericarpium Citri tangerinae, Pericarpium Citri tangerinae, Citrus chachiensis Hort. C. Suavissima Tanaka, Pericarpium citri reticuatae chachiensis; [English name] Citrus reticulata Blanco.[Latin] Pericarpium Citri Reticulatae, the young fruit of rutaceae orange and variety thereof or the peel of immature fruit; [nature and flavor] are " Chinese Pharmacopoeia " gas perfume (or spice) 1., acrid in the mouth, hardship; [function cures mainly] regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, the distension and fullness in the abdomen of stagnation of QI in spleen and stomach or pain, dyspepsia.1. " medicine origin ": Pericarpium Citri tangerinae energy QI invigorating, add Pericarpium Citri Reticulatae Viride and reduce by half, remove stagnant gas, push away Chen Zhixin.2. " daily book on Chinese herbal medicine ": Pericarpium Citri tangerinae, can fall apart and can rush down, can temperature can mend the diaphragm gas that can disappear, the saliva that reduces phlegm, and spleen antitussive, logical five types of stranguria.3. " medicine origin ": go cold-evil in the heart, broken stagnant gas, strengthening the spleen stomach.
Fructus Phyllanthi, [another name] emblic leafflower fruit, meter Han, prestige fruit, wooden ripple, seven are examined sorrow happiness, the public fat of Lu, Phyllanthus emblica L.; [Latin] Phyllanthus emblica; Euphorbiaceae, is born in height above sea level 200-2300 rice mountain region sparse woods, shrubbery, wasteland or gully area without shade.The ground such as distribution Jiangxi, Fujian, Guangdong, Hainan, Guangxi, Sichuan.[nature and flavor] are sweet, micro-puckery, cool.1. " Chinese Pharmacopoeia "--really: clearing away heat and cooling blood, promoting digestion and invigorating the stomach, the cough-relieving of promoting the production of body fluid.2. " national Chinese herbal medicine compilation " root: for hypertension, stomachache, enteritis, tuberculous lymphadenitis.[function cures mainly] heat in blood blood stasis, dyspepsia, abdominal distention, cough, laryngalgia, xerostomia and vitamin C deficiency disease.
Flos Lonicerae, [another name] Flos Lonicerae, little egret flower, Flos Lonicerae, Flos Lonicerae, Flos Lonicerae, golden rattan, two bud flower, JINHUA, two precious flowers; Come from Compendium of Material Medica, [English
name]flos Lonicerae[Latin] Lonicera japonica Thunb. shrub, Caprifoliaceae; Flavor efficacy: cold in nature, sweet in the mouth.The effect with heat-clearing and toxic substances removing, wind-heat dissipating, antiinflammatory, tonify deficiency treatment wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.Effect: 1, resisting pathogenic microbes: experiment in vitro shows, flower and rattan all have certain inhibitory action to various pathogens as staphylococcus aureus, Hemolytic streptococcus, escherichia coli, dysentery bacterium, vibrio cholera, Bacillus typhi, Salmonella paratyphi etc., also effective to streptococcus pneumoniae, meningococcus, bacillus pyocyaneus, tubercule bacillus.2, booster immunization function: Flos Lonicerae decoct is diluted to the concentration of 1:1280, still can promote leukocytic phagocytic function.
Armeniaca mume Sieb., [another name] dark plum, Fructus Armeniacae Mume; [Latin] Vatica mangachapoi Blanco Dipterocarpaceae; Flavor efficacy: Gan Ping, " legendary god of farming's book on Chinese herbal medicine " definiteness sweet in the mouth is flat, can enter liver, spleen, lung, large intestine, has the convergence effect of promoting the production of body fluid.The people trusted subordinate cold type of pain of suitable cold syndrome of the stomach, borborygmus diarrhoea person, poor appetite, anorexia, or it is edible to stop the people of dyspepsia.Compendium of Material Medica: " in warm, ward off communicable subtropical diseases bad odor, control trusted subordinate's cold type of pain, cold-damp cholera.", " book on Chinese herbal medicine converges and says ": " control and stop dyspepsia, all cards of all excessive cold invading middle-JIAO(the spleen and stomach)." there is the therapeutic method to keep the adverse QI flowing downwards, feel at ease, cough-relieving antitussive, pain relieving stop typhoid fever dysphoria with smothery sensation, stops cold and hot dysentery, effect of subduing swelling and detoxicating.
Wine cake wood, [another name] wild husky Citrus chachiensis Hort., meal soup wood, wine cake wood (" Guangxi medicine is planted register "), mountain Phyllanthus emblica L., mountain Fructus Citri tangerinae (" conventional Chinese herbal medicine color atlas "), Radix Glycosmidis Citrifoliae, Chinese lime, false Fructus Fortunellae Margaritae, water remaining piece; [English name] Root of Citrusleaf Glycosmis[Latin]
glycosmis citrifloia (Willd) Lindl.bald clean shrub, Rutaceae; [nature and flavor] are " conventional Chinese herbal medicine color atlas " 1.: root: pungent, and temperature; Leaf: micro-sweet, temperature.2. " Guangxi Chinese herbal medicine ": micro-arduous, flat.[function cures mainly] expelling pathogenic wind from the body surface, reduces phlegm, cough-relieving, removing food stagnancy, dissipating blood stasis.The cough that cures cold, abdominal pain due to retention of food, colicky.1. " Guangxi medicine is planted register ": root: analgesia preventing or arresting vomiting, dispelling the wind and dampness pathogens, cough.2. " conventional Chinese herbal medicine color atlas ": dispel the wind and deliver, circulation of qi promoting cough-relieving.The cough that cures cold, hernia pain due to disorder of QI, chilblain.3. " Guangxi Chinese herbal medicine ": eliminate the phlegm, dissipating blood stasis, removing food stagnancy.Control abdominal pain due to retention of food, treating swelling and pain by traumatic injury.
Above-described relieving cough and resolving phlegm buccal tablet is tentatively on probation in clinical treatment cough, laryngopharynx swelling and pain project, and reflection is good, without obvious toxic-side effects.
Above-mentioned each component medicine is made the preparation method of relieving cough and resolving phlegm buccal tablet of the present invention:
(1) by weight dry Folium Eriobotryae, Pericarpium Citri Reticulatae, Fructus Phyllanthi, Flos Lonicerae, Armeniaca mume Sieb. and wine cake wood are broken into lOO-120 object fine powder; Medicated powder is poured in pithos and is soaked 40 minutes, add the water yield be medicine gross weight 8-10 doubly, boil 1-2 hour, in the time that fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(2) medicinal residues after filtering in step 1 are added the water yield be medicine gross weight 3-5 doubly, boil 0.5-1 hour, in the time that fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(3) extracting solution step 1 and step 2 being obtained mixes, and is condensed into thick paste, adds wet and slippery dose of mix homogeneously to make soft material;
(4) soft material is crossed to 18 orders, then dry under 50-60 DEG C of condition, gained granule carries out tabletting, makes Traditional Chinese medicine lozenge.
Above-described wet and slippery dose is one or more in stearate, Pulvis Talci, hydride vegetable oil, Polyethylene Glycol.
Above-mentioned Chinese medicine of the present invention, according to different situations and pharmaceutical factory condition, can also make other preparation.Buccal tablet of the present invention also can coordinate the clinical use of other medicaments,
the invention has the beneficial effects as follows:
1, the present invention plays cough-relieving, reduces phlegm, detumescence, and removing toxic substances, analgesia, the effect of eliminating the phlegm, has significant curative effect to human therapy cough, laryngopharynx swelling and pain, laryngalgia, particularly right cough and expectoration, laryngopharynx swelling and pain.
2, use and all can fully recover for 3-5 of the present invention days, cure rate is more than 80%, and effective percentage is more than 90%, human body to be had no side effect, and easy to use, cost is low.
detailed description of the invention
Embodiment 1:
(1) by weight wooden 8 parts of 30 parts of dry Folium Eriobotryaes, 30 parts of Pericarpium Citri Reticulataes, 15 parts of Fructus Phyllanthis, 15 parts of Flos Loniceraes, 15 parts, Armeniaca mume Sieb. and wine cake is broken into 120 object fine powders; Medicated powder is poured in pithos and soaked 40 minutes, and adding the water yield is 10 times of medicine gross weight, boils 2 hours, in the time that fluid temperature is down to 30 DEG C-60 DEG C, filters, and obtains extracting solution;
(2) medicinal residues after filtering in step 1 being added to the water yield is 5 times of medicine gross weight, boils 1 hour, in the time that fluid temperature is down to 30 DEG C-60 DEG C, filters, and obtains extracting solution;
(3) extracting solution step 1 and step 2 being obtained mixes, and is condensed into thick paste, adds Polyethylene Glycol mix homogeneously to make soft material;
(4) soft material is crossed to 18 orders, then dry under 60 DEG C of conditions, gained granule carries out tabletting, makes Traditional Chinese medicine lozenge.
Embodiment 2:
(1) by weight wooden 7 parts of 28 parts of dry Folium Eriobotryaes, 28 parts of Pericarpium Citri Reticulataes, 14 parts of Fructus Phyllanthis, 14 parts of Flos Loniceraes, 14 parts, Armeniaca mume Sieb. and wine cake is broken into 120 object fine powders; Medicated powder is poured in pithos and soaked 40 minutes, and adding the water yield is 10 times of medicine gross weight, boils 1.5 hours, in the time that fluid temperature is down to 30 DEG C-60 DEG C, filters, and obtains extracting solution;
(2) medicinal residues after filtering in step 1 being added to the water yield is 5 times of medicine gross weight, boils 0.8 hour, in the time that fluid temperature is down to 30 DEG C-60 DEG C, filters, and obtains extracting solution;
(3) extracting solution step 1 and step 2 being obtained mixes, and is condensed into thick paste, adds hydride vegetable oil mix homogeneously to make soft material;
(4) soft material is crossed to 18 orders, then dry under 58 DEG C of conditions, gained granule carries out tabletting, makes Traditional Chinese medicine lozenge.
Embodiment 3:
(1) by weight wooden 7 parts of 22 parts of dry Folium Eriobotryaes, 22 parts of Pericarpium Citri Reticulataes, 12 parts of Fructus Phyllanthis, 12 parts of Flos Loniceraes, 12 parts, Armeniaca mume Sieb. and wine cake is broken into 110 object fine powders; Medicated powder is poured in pithos and soaked 40 minutes, and adding the water yield is 9 times of medicine gross weight, boils 1 hour, in the time that fluid temperature is down to 30 DEG C-60 DEG C, filters, and obtains extracting solution;
(2) medicinal residues after filtering in step 1 being added to the water yield is 4 times of medicine gross weight, boils 0.5 hour, in the time that fluid temperature is down to 30 DEG C-60 DEG C, filters, and obtains extracting solution;
(3) extracting solution step 1 and step 2 being obtained mixes, and is condensed into thick paste, adds stearate mix homogeneously to make soft material;
(4) soft material is crossed to 18 orders, then dry under 55 DEG C of conditions, gained granule carries out tabletting, makes Traditional Chinese medicine lozenge.
Embodiment 4:
(1) by weight wooden 6 parts of 20 parts of dry Folium Eriobotryaes, 20 parts of Pericarpium Citri Reticulataes, 10 parts of Fructus Phyllanthis, 10 parts of Flos Loniceraes, 10 parts, Armeniaca mume Sieb. and wine cake is broken into l00 object fine powder; Medicated powder is poured in pithos and soaked 40 minutes, and adding the water yield is 8 times of medicine gross weight, boils 1 hour, in the time that fluid temperature is down to 30 DEG C-60 DEG C, filters, and obtains extracting solution;
(2) medicinal residues after filtering in step 1 being added to the water yield is 3 times of medicine gross weight, boils 0.5 hour, in the time that fluid temperature is down to 30 DEG C-60 DEG C, filters, and obtains extracting solution;
(3) extracting solution step 1 and step 2 being obtained mixes, and is condensed into thick paste, adds stearate and Pulvis Talci mix homogeneously to make soft material;
(4) soft material is crossed to 18 orders, then dry under 50 DEG C of conditions, gained granule carries out tabletting, makes Traditional Chinese medicine lozenge.
clinical therapeutic efficacy:
In order to show that medicine of the present invention, to cough and expectoration, laryngopharynx swelling and pain therapeutic effect, has carried out following clinical experiment, since 2011, treat altogether cough and expectoration patient 158 examples, cure and reach 136 person-times, transfer well 15 person-times to, invalid is 7 people, and cure rate can reach 86.1%, and effective percentage can reach 95.5%; Treatment laryngopharynx swelling and pain patient 136 examples, cure and reach 113 person-times, effectively can reach 14 person-times, and invalid is 9 person-times, and cure rate is 83.1%, and it is 84.7% that effective percentage can reach 93.3% its total cure rate, and total effective rate is 94.6%.
Can draw according to the practice of traditional Chinese medical science pharmacology and clinical treatment: relieving cough and resolving phlegm buccal tablet has significant effect to diseases such as treatment cough and expectoration, laryngopharynx swelling and pain, can be widely used in clinical treatment and use.
Model case:
Case 1: Chen, man, 48 years old, people from Guigang, Guangxi, suffered from influenza and follows cough, abundant expectoration, took and after Western medicine, was not still clearly better for many days, through taking relieving cough and resolving phlegm buccal tablet of the present invention remission after 2 days, took recovery from illness afterwards in 5 days.
Case 2: not so-and-so, female, 4 years old, Guigang, Guangxi province, suffered from an inflammation of the lungs, and at pediatric transfusion and Comprehensive Treatment, still had the symptoms such as cough, abundant expectoration, took buccal tablet of the present invention second day, cough alleviates, expectorant is few, infant recovery from illness after 5 days.
Case 3: Zhang, man, 46 years old, Mu Gen people from town, Guigang, Guangxi, was engaged in teaching job, because job specification need to be attended class continuously on dais, the frequent laryngopharynx swelling and pain of Mr. Zhang all take the buccal tablet for the treatment of laryngopharynx swelling and pain, but effect is slow at every turn, treatment time is long, just can fully recover after 3 days through having taken relieving cough and resolving phlegm buccal tablet of the present invention.
Case 4: Zhao so-and-so, man, 28 years old, ocean town, Guigang, Guangxi main road ridge people from village, causes cough and expectoration because suffering from upper respiratory tract infection, within several days, is clearly better for seeing at hospital transfusion, through taken relieving cough and resolving phlegm buccal tablet of the present invention after 3 days symptom alleviate, after 7 days, cough and expectoration is just fully recovered.
Case 5: Zhu, man, 53 years old, Tantang District, Guigang, Guangxi Qin Tang people from town, because of suffer from bronchitis cause cough and expectoration, within several days, be clearly better for seeing at hospital transfusion, through taken relieving cough and resolving phlegm buccal tablet of the present invention after 2 days symptom alleviate, good after 5 days.
Claims (4)
1. a relieving cough and resolving phlegm buccal tablet, is made up of the raw material of following parts by weight: Folium Eriobotryae 20-30 part, Pericarpium Citri Reticulatae 20-30 part, Fructus Phyllanthi 10-15 part, Flos Lonicerae 10-15 part, dark plum 10-15 part, wine cake wood 5-8 part.
2. relieving cough and resolving phlegm buccal tablet according to claim 1, is characterized in that: the raw material by following parts by weight is made: Folium Eriobotryae 25-28 part, Pericarpium Citri Reticulatae 25-28 part, Fructus Phyllanthi 12-15 part, Flos Lonicerae 12-15 part, Armeniaca mume Sieb. 12-15 part, wine cake wood 6-8 part.
3. a preparation method for relieving cough and resolving phlegm buccal tablet, is characterized in that:
(1) by weight dry Folium Eriobotryae, Pericarpium Citri Reticulatae, Fructus Phyllanthi, Flos Lonicerae, Armeniaca mume Sieb. and wine cake wood are broken into lOO-120 object fine powder; Medicated powder is poured in pithos and is soaked 40 minutes, add the water yield be medicine gross weight 8-10 doubly, boil 1-2 hour, in the time that fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(2) medicinal residues after filtering in step 1 are added the water yield be medicine gross weight 3-5 doubly, boil 0.5-1 hour, in the time that fluid temperature is down to 30 DEG C-60 DEG C, filter, obtain extracting solution;
(3) extracting solution step 1 and step 2 being obtained mixes, and is condensed into thick paste, adds wet and slippery dose of mix homogeneously to make soft material;
(4) soft material is crossed to 18 orders, then dry under 50-60 DEG C of condition, gained granule carries out tabletting, makes Traditional Chinese medicine lozenge.
4. the preparation method of the stagnant buccal tablet that helps digestion according to claim 3, is characterized in that: described wet and slippery dose is one or more in stearate, Pulvis Talci, hydride vegetable oil, Polyethylene Glycol.
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| CN105380275A (en) * | 2015-10-27 | 2016-03-09 | 全椒井府富硒生态牧业有限公司 | Selenium-rich emblic leafflower lozenge and preparing method thereof |
| CN110327420A (en) * | 2019-07-24 | 2019-10-15 | 广州中医药大学第一附属医院 | A kind of mouth containing plum and preparation method thereof |
| CN116492437A (en) * | 2023-03-24 | 2023-07-28 | 云南贝泰妮生物科技集团股份有限公司 | Plant buccal tablet for improving respiratory tract immunity and preparation process thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105233110A (en) * | 2015-10-16 | 2016-01-13 | 雷霜 | Traditional Chinese medicine preparation for prevention and treatment of bovine bronchopneumonia and production method of traditional Chinese medicine preparation for prevention and treatment of bovine bronchopneumonia |
| CN105380275A (en) * | 2015-10-27 | 2016-03-09 | 全椒井府富硒生态牧业有限公司 | Selenium-rich emblic leafflower lozenge and preparing method thereof |
| CN110327420A (en) * | 2019-07-24 | 2019-10-15 | 广州中医药大学第一附属医院 | A kind of mouth containing plum and preparation method thereof |
| CN110327420B (en) * | 2019-07-24 | 2021-04-23 | 广州中医药大学第一附属医院 | Buccal plum and preparation method thereof |
| CN116492437A (en) * | 2023-03-24 | 2023-07-28 | 云南贝泰妮生物科技集团股份有限公司 | Plant buccal tablet for improving respiratory tract immunity and preparation process thereof |
| CN116492437B (en) * | 2023-03-24 | 2023-12-12 | 云南贝泰妮生物科技集团股份有限公司 | Plant buccal tablet for improving respiratory tract immunity and preparation process thereof |
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| CN104027440B (en) | 2016-01-13 |
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