CN104023744A - 用于针对金黄色葡萄球菌免疫的稳定组合物 - Google Patents

用于针对金黄色葡萄球菌免疫的稳定组合物 Download PDF

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Publication number
CN104023744A
CN104023744A CN201280063615.8A CN201280063615A CN104023744A CN 104023744 A CN104023744 A CN 104023744A CN 201280063615 A CN201280063615 A CN 201280063615A CN 104023744 A CN104023744 A CN 104023744A
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CN
China
Prior art keywords
antigen
seq
sta006
polypeptide
esxab
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Pending
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CN201280063615.8A
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English (en)
Chinese (zh)
Inventor
M·肯托尼
L·塔里
A·考斯洛维
M·索特朱
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Novartis AG
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Novartis AG
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Publication of CN104023744A publication Critical patent/CN104023744A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CN201280063615.8A 2011-12-23 2012-12-21 用于针对金黄色葡萄球菌免疫的稳定组合物 Pending CN104023744A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161580191P 2011-12-23 2011-12-23
US61/580,191 2011-12-23
PCT/EP2012/076609 WO2013092985A1 (en) 2011-12-23 2012-12-21 Stable compositions for immunising against staphylococcus aureus

Publications (1)

Publication Number Publication Date
CN104023744A true CN104023744A (zh) 2014-09-03

Family

ID=47520086

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280063615.8A Pending CN104023744A (zh) 2011-12-23 2012-12-21 用于针对金黄色葡萄球菌免疫的稳定组合物

Country Status (5)

Country Link
US (1) US20150044251A1 (cg-RX-API-DMAC10.html)
EP (1) EP2793939A1 (cg-RX-API-DMAC10.html)
JP (1) JP2015500864A (cg-RX-API-DMAC10.html)
CN (1) CN104023744A (cg-RX-API-DMAC10.html)
WO (1) WO2013092985A1 (cg-RX-API-DMAC10.html)

Cited By (1)

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CN113893340A (zh) * 2021-09-30 2022-01-07 中牧实业股份有限公司 双相油佐剂口蹄疫疫苗的稳定剂及其应用

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AU2012214677B2 (en) 2011-02-08 2016-11-10 Abvacc, Inc. Immunogenic composition comprising alpha-hemolysin oligopeptides
WO2013162746A1 (en) * 2012-04-26 2013-10-31 University Of Chicago Staphylococcal coagulase antigens and methods of their use
TR201910573T4 (tr) 2012-08-31 2019-08-21 Glaxosmithkline Biologicals Sa Staphylococcus aureus'a karşı bağışıklık kazandırmak için stabilize edilmiş proteinler.
EP3077820B1 (en) * 2013-12-03 2025-02-26 Evaxion Biotech A/S Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus
MX377794B (es) 2014-03-26 2025-03-10 Glaxosmithkline Biologicals Sa Antigenos estafilococicos mutantes.
CN104147599B (zh) * 2014-06-24 2017-03-01 华中科技大学 一种疫苗佐剂、其制备方法及应用
WO2016095832A1 (en) * 2014-12-18 2016-06-23 The University Of Hong Kong Immunotherapeutic targets against staphylococcus aureus
US10946084B2 (en) 2016-02-22 2021-03-16 Evaxion Biotech Aps Proteins and nucleic acids useful in vaccines targeting Staphylococcus aureus
WO2023172741A2 (en) * 2022-03-11 2023-09-14 The Children's Medical Center Corporation A multiple antigen presenting system (maps)-based staphylococcus aureus vaccine comprising b- and t-cell antigens, immunogenic composition, and uses thereof
US20250288657A1 (en) * 2022-05-04 2025-09-18 Evaxion Biotech A/S Staphylococcal protein variants and truncates

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CN1927394A (zh) * 2006-09-05 2007-03-14 重庆康卫生物科技有限公司 口服重组幽门螺杆菌疫苗及其制备方法
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CN102258537A (zh) * 2011-07-15 2011-11-30 骆延波 鸡传染性法氏囊病特异性转移因子的制备方法

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113893340A (zh) * 2021-09-30 2022-01-07 中牧实业股份有限公司 双相油佐剂口蹄疫疫苗的稳定剂及其应用

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Publication number Publication date
WO2013092985A1 (en) 2013-06-27
EP2793939A1 (en) 2014-10-29
US20150044251A1 (en) 2015-02-12
JP2015500864A (ja) 2015-01-08

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Application publication date: 20140903