CN103989893A - Traditional Chinese medicinal composition for treating dysmenorrhea, as well as preparation method and application thereof - Google Patents
Traditional Chinese medicinal composition for treating dysmenorrhea, as well as preparation method and application thereof Download PDFInfo
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- CN103989893A CN103989893A CN201410268390.0A CN201410268390A CN103989893A CN 103989893 A CN103989893 A CN 103989893A CN 201410268390 A CN201410268390 A CN 201410268390A CN 103989893 A CN103989893 A CN 103989893A
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Abstract
The invention provides a traditional Chinese medicinal composition for treating dysmenorrhea. The composition is prepared from the following raw medicinal materials in parts by weight: 10-20 parts of lonicera ferdinandii, 10-20 parts of Japanese red, 4-8 parts of suberect spatholobus stem, 4-8 parts of rhizoma panacis majoris, 10-20 parts of China rose, 3-7 parts of saruma henryi, 8-16 parts of falsenettleleaf pepper stem, 4-8 parts of false aloe, 8-12 parts of calystegia hederacea wall, 4-8 parts of tofieldia thibetica, 4-8 parts of pungent litse fruit and 1-3 parts of cinnamon, and can be used for activating blood circulation to remove stasis, regulating qi and relieving pain. The invention also relates to a preparation method and application thereof.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition and preparation method and application that are used for the treatment of dysmenorrhea.
Background technology
Dysmenorrhea is the periodicity lower abdominal pain occurring before and after menstrual phase and menstrual phase, often occurs in a month premenstrual and menstrual phase, accidentally occurs in after menstrual phase in a few days.Lower abdominal pain is Crampy Pain and distending pain, can be radiated to around lumbosacral region, femoribus internus and anus.Can be with pale complexion, feel sick, vomiting, whole body or hypogastric region fear of cold, frequency of bowel movement, dol urg can be collapsed.Dysmenorrhea degree relies on subjective sensation, and without objective criterion, so incidence rate differs.Two kinds of dysmenorrhea minute constitutional and Secondary cases.Secondary dysmenorrhea occurred in menophania after 2 years, and age, the course of disease of various disease dysmenorrhea differ, and the morning and evening that dysmenorrhea occurs is also different.The treatment of the traditional Chinese medical science to primary disease, take that to regulate the flow of vital energy, invigorate blood circulation, change tired be the rule for the treatment of, but lacks in the market real effectively patent medicine.
Summary of the invention
Goal of the invention: in order to address the above problem, the object of the present invention is to provide a kind of Chinese medicine composition and preparation method and application that are used for the treatment of dysmenorrhea.
Technical scheme: the object of the invention is to realize by following scheme:
Treat a Chinese medicine composition for dysmenorrhea, it is extracted and is prepared by the crude drug of following parts by weight: thousand layers of skin 10-20 part, large and red 10-20 part, Caulis Spatholobi 4-8 part, Rhizoma Panacis Majoris 4-8 part, Flos Rosae Chinensis 10-20 part, Herba Asari 3-7 part, Caulis Piperis Boehmeriaefolii 8-16 part, false aloe 4-8 part, Pu L.Lucidus Turcz. 8-12 part, Rhizoma Bergeniae purpurascentis 4-8 part, Fructus Litseae pungentis 4-8 part, Cortex Cinnamomi 1-3 part.
The Chinese medicine composition of described treatment dysmenorrhea, it is extracted and is prepared by the crude drug of following parts by weight: 15 parts of thousand layers of skins, large and red 15 parts, 6 parts of Caulis Spatholobis, 6 parts of Rhizoma Panacis Majoris, 15 parts of Flos Rosae Chinensiss, 5 parts of Herba Asaris, 12 parts of Caulis Piperis Boehmeriaefoliis, 6 parts of false aloes, 10 parts of Pu L.Lucidus Turcz., 6 parts of Rhizoma Bergeniae purpurascentis, 6 parts of Fructus Litseae pungentiss, 2 parts of Cortex Cinnamomis.
The Chinese medicine composition of described treatment dysmenorrhea, it comprises the steps: to get thousand layers of skin, large and red, Caulis Spatholobi, Rhizoma Panacis Majoris, Flos Rosae Chinensis, Herba Asari, Caulis Piperis Boehmeriaefolii, false aloe, Pu L.Lucidus Turcz., Rhizoma Bergeniae purpurascentis, Fructus Litseae pungentis, Cortex Cinnamomi medical material merges, decoct with water twice, amount of water is 10 times of amounts of medical material weight, decoct 2h, collecting decoction, while being concentrated into 65 ℃, relative density is 1.10, adding ethanol makes to reach 65% containing the percent by volume of alcohol amount, stir, standing, filter, when filtrate decompression is concentrated into 65 ℃, relative density is 1.20 and reclaims ethanol, concentrated solution spraying is dry, add adjuvant and make capsule, tablet, granule.
The Chinese medicine composition of described treatment dysmenorrhea, the drying condition of spraying in described preparation method is: inlet temperature is 80-120 ℃, and leaving air temp is 80-90 ℃, and temperature of charge is 70-90 ℃, and atomizing pressure is 0.2-0.4 MPa, spray velocity is 5-10ml/s.
The application of the Chinese medicine composition of described treatment dysmenorrhea in preparation treatment dysmenorrhea medicine.
Thousand layers of skin of Raw of the present invention are the root for moraceae plants cudrania cochinchinensis or Zhe Shu, large and red is Dou Ke Jing tip platymiscium Mao Jing tip Campylotropis hirtella (Franch.) Schindl.[Lespedeza hirtella Franch.], with root, be used as medicine, Caulis Spatholobi is for being leguminous plant spatholobus suberectus (Caulis Sargentodoxae, Radix seu Caulis Verntilaginis Leiocarpae, SANYE Caulis Spatholobi, nine layers of wind) the dry rattan of Spatholobus suberectus Dunn, Rhizoma Panacis Majoris is the root of Campanulaceae pearl, Flos Rosae Chinensis is the dried floral of rosaceous plant Chinese rose Rosa chinensis Jacq., Herba Asari is root and rhizome or the leaf of feverfew Herba Ainsliaeae elegantis, Caulis Piperis Boehmeriaefolii is the Herb of Piperaceae plant folium urticae Fructus Piperis, false aloe is herb or the root of liliaceous plant false aloe, Pu L.Lucidus Turcz. is herb or the root of dicotyledon scammonia section plant DAWANHUA, Rhizoma Bergeniae purpurascentis is the rhizome of saxifragaceae plant Rhizoma Seu Herba Bergeniae, Fructus Litseae pungentis is the fruit of Lauraceae Litsea plant Fructus Litseae pungentis Litsea pungens Hemsl., and all the other are pharmacopeia kind.
Beneficial effect:
From theory of Chinese medical science, thousand layers of skin in we, large and red, Rhizoma Panacis Majoris, false aloe, Flos Rosae Chinensis, Herba Asari, blood circulation promoting and blood stasis dispelling are monarch drug, Pu L.Lucidus Turcz. is enriched blood, Rhizoma Bergeniae purpurascentis, Fructus Litseae pungentis, the pain relieving of Caulis Piperis Boehmeriaefolii regulating the flow of QI to promote menstrual discharge, be minister altogether, Cortex Cinnamomi, Caulis Spatholobis etc. are adjuvant, all medicines are harmonious, play altogether blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain effect, is used for the treatment of dysmenorrhea.Formulation of the present invention is reasonable, and compatibility is rigorous, through long-term clinical verification, determined curative effect.Consist of Chinese crude drug, have no side effect, low price.
The specific embodiment
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as to the scope of the above-mentioned theme of the present invention only limits to following example, all technology realizing based on foregoing of the present invention all belong to scope of the present invention.
One, Preparation Example 1: get thousand layers of skin 15g, large and red 15g, Caulis Spatholobi 6g, Rhizoma Panacis Majoris 6g, Flos Rosae Chinensis 15g, Herba Asari 5g, Caulis Piperis Boehmeriaefolii 12g, false aloe 6g, Pu L.Lucidus Turcz. 10g, Rhizoma Bergeniae purpurascentis 6g, Fructus Litseae pungentis 6g, Cortex Cinnamomi 2g medical material merges, decoct with water twice, amount of water is 10 times of amounts of medical material weight, decoct 2h, collecting decoction, while being concentrated into 65 ℃, relative density is 1.10, adding ethanol makes to reach 65% containing the percent by volume of alcohol amount, stir, standing, filter, when filtrate decompression is concentrated into 65 ℃, relative density is 1.20 and reclaims ethanol, concentrated solution spraying is dry, spraying drying condition is: inlet temperature is 100 ℃, leaving air temp is 80 ℃, temperature of charge is 70 ℃, atomizing pressure is 0.2 MPa, spray velocity is 5ml/s, add starch and make capsule.
Preparation Example 2: get thousand layers of skin 15g, large and red 15g, Caulis Spatholobi 6g, Rhizoma Panacis Majoris 6g, Flos Rosae Chinensis 15g, Herba Asari 5g, Caulis Piperis Boehmeriaefolii 12g, false aloe 6g, Pu L.Lucidus Turcz. 10g, Rhizoma Bergeniae purpurascentis 6g, Fructus Litseae pungentis 6g, Cortex Cinnamomi 2g medical material merges, decoct with water twice, amount of water is 10 times of amounts of medical material weight, decoct 2h, collecting decoction, while being concentrated into 65 ℃, relative density is 1.10, adding ethanol makes to reach 65% containing the percent by volume of alcohol amount, stir, standing, filter, when filtrate decompression is concentrated into 65 ℃, relative density is 1.20 and reclaims ethanol, concentrated solution spraying is dry, spraying drying condition is: inlet temperature is 100 ℃, leaving air temp is 80 ℃, temperature of charge is 70 ℃, atomizing pressure is 0.2 MPa, spray velocity is 5ml/s, add starch, pelletizing press sheet is made tablet.
Two, the clinical trial data of the present invention to dysmenorrhea
The physical data of experimental subject: adopting Chinese medicine composition of the present invention to treat altogether 100 examples, is women entirely, the oldest person 42 years old, age reckling 16 years old.
Therapeutic Method: usage and dosage: adopt the prepared capsule of the embodiment of the present invention 1, its usage and consumption are each 8, and every day 3 times, warm water takes, and one month is a course for the treatment of, treats altogether for 3 courses for the treatment of.
The standard of curative effect evaluation
Cure: sign and symptom are improved completely, happy, in high spirits.
Effective: sign and symptom are significantly improved, happy, spirit is fine.
Effective: sign and symptom change, suddenly feel slightly little suitable, but can accept.
Invalid: sign is without change, and symptom is as front.
In the 100 routine cases of accepting for medical treatment, through treatment in 3 months, wherein cure 48 examples, effective 36 examples, effective 12 examples, invalid 6 examples, total effective rate reaches 96%.
Result shows, Chinese medicine composition of the present invention has extremely significant effect to treatment dysmenorrhea patient.
Claims (5)
1. a Chinese medicine composition for the treatment of dysmenorrhea, it is characterized in that, it is extracted and is prepared by the crude drug of following parts by weight: thousand layers of skin 10-20 part, large and red 10-20 part, Caulis Spatholobi 4-8 part, Rhizoma Panacis Majoris 4-8 part, Flos Rosae Chinensis 10-20 part, Herba Asari 3-7 part, Caulis Piperis Boehmeriaefolii 8-16 part, false aloe 4-8 part, Pu L.Lucidus Turcz. 8-12 part, Rhizoma Bergeniae purpurascentis 4-8 part, Fructus Litseae pungentis 4-8 part, Cortex Cinnamomi 1-3 part.
2. treat as claimed in claim 1 the Chinese medicine composition of dysmenorrhea, it is characterized in that, it is extracted and is prepared by the crude drug of following parts by weight: 15 parts of thousand layers of skins, large and red 15 parts, 6 parts of Caulis Spatholobis, 6 parts of Rhizoma Panacis Majoris, 15 parts of Flos Rosae Chinensiss, 5 parts of Herba Asaris, 12 parts of Caulis Piperis Boehmeriaefoliis, 6 parts of false aloes, 10 parts of Pu L.Lucidus Turcz., 6 parts of Rhizoma Bergeniae purpurascentis, 6 parts of Fructus Litseae pungentiss, 2 parts of Cortex Cinnamomis.
3. treat as claimed in claim 1 the Chinese medicine composition of dysmenorrhea, it is characterized in that, it comprises the steps: to get thousand layers of skin, large and red, Caulis Spatholobi, Rhizoma Panacis Majoris, Flos Rosae Chinensis, Herba Asari, Caulis Piperis Boehmeriaefolii, false aloe, Pu L.Lucidus Turcz., Rhizoma Bergeniae purpurascentis, Fructus Litseae pungentis, Cortex Cinnamomi medical material merges, decoct with water twice, amount of water is 10 times of amounts of medical material weight, decoct 2h, collecting decoction, while being concentrated into 65 ℃, relative density is 1.10, adding ethanol makes to reach 65% containing the percent by volume of alcohol amount, stir, standing, filter, when filtrate decompression is concentrated into 65 ℃, relative density is 1.20 and reclaims ethanol, concentrated solution spraying is dry, add adjuvant and make capsule, tablet, granule.
4. treat as claimed in claim 3 the Chinese medicine composition of dysmenorrhea, it is characterized in that, the drying condition of spraying in described preparation method is: inlet temperature is 80-120 ℃, leaving air temp is 80-90 ℃, temperature of charge is 70-90 ℃, and atomizing pressure is 0.2-0.4 MPa, and spray velocity is 5-10ml/s.
5. described in claim 1, treat the Chinese medicine composition of dysmenorrhea and treat the application in dysmenorrhea medicine in preparation.
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| CN201410268390.0A CN103989893A (en) | 2014-06-16 | 2014-06-16 | Traditional Chinese medicinal composition for treating dysmenorrhea, as well as preparation method and application thereof |
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| CN201410268390.0A CN103989893A (en) | 2014-06-16 | 2014-06-16 | Traditional Chinese medicinal composition for treating dysmenorrhea, as well as preparation method and application thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104800762A (en) * | 2015-05-02 | 2015-07-29 | 淄博齐鼎立专利信息咨询有限公司 | Traditional Chinese medicine composition for treating dysmenorrhea |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101028404A (en) * | 2007-04-16 | 2007-09-05 | 北京艺信堂医药研究所 | Chinese-medicinal decoction for treating difficult menstruation |
| CN101543610A (en) * | 2009-02-18 | 2009-09-30 | 曹莹莹 | Medical wine for effectively treating menalgia |
| CN101716273A (en) * | 2009-12-25 | 2010-06-02 | 黄毅 | Traditional Chinese medicine for treating dysmenorrhea |
| CN101912593A (en) * | 2010-08-05 | 2010-12-15 | 吴红霞 | Medicament for treating dysmenorrheal and preparation method thereof |
| CN102188554A (en) * | 2010-03-16 | 2011-09-21 | 陈偲偲 | Tongjingning capsule |
-
2014
- 2014-06-16 CN CN201410268390.0A patent/CN103989893A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101028404A (en) * | 2007-04-16 | 2007-09-05 | 北京艺信堂医药研究所 | Chinese-medicinal decoction for treating difficult menstruation |
| CN101543610A (en) * | 2009-02-18 | 2009-09-30 | 曹莹莹 | Medical wine for effectively treating menalgia |
| CN101716273A (en) * | 2009-12-25 | 2010-06-02 | 黄毅 | Traditional Chinese medicine for treating dysmenorrhea |
| CN102188554A (en) * | 2010-03-16 | 2011-09-21 | 陈偲偲 | Tongjingning capsule |
| CN101912593A (en) * | 2010-08-05 | 2010-12-15 | 吴红霞 | Medicament for treating dysmenorrheal and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104800762A (en) * | 2015-05-02 | 2015-07-29 | 淄博齐鼎立专利信息咨询有限公司 | Traditional Chinese medicine composition for treating dysmenorrhea |
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Application publication date: 20140820 |
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