CN103977133B - A kind of Chinese medicine preparation for the treatment of female climacteric syndrome - Google Patents

A kind of Chinese medicine preparation for the treatment of female climacteric syndrome Download PDF

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CN103977133B
CN103977133B CN201410218369.XA CN201410218369A CN103977133B CN 103977133 B CN103977133 B CN 103977133B CN 201410218369 A CN201410218369 A CN 201410218369A CN 103977133 B CN103977133 B CN 103977133B
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radix
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herba
chinese medicine
climacteric syndrome
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CN103977133A (en
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张囡囡
张有涛
郝立鹏
张海英
吴晓青
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Abstract

The invention discloses a kind of Chinese medicine preparation for the treatment of female climacteric syndrome, be made up of the crude drug of following weight portion: Radix Angelicae Sinensis 18-24 part, Radix Paeoniae Alba 15-20 part, Radix Rehmanniae Preparata 15-20 part, Radix Scutellariae 15-20 part, Rhizoma Chuanxiong 12-16 part, Fructus Corni 12-16 part, Radix Glycyrrhizae 8-12 part, Radix Chloranthi Serrati 5-10 part, Herba chloranthi japonici 5-10 part, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 5-10 part, Flos Campsis 5-10 part, Herba Silenes conoideae 5-10 part, Aquilegia yabeana 4-8 part, Herba Pyrolae 4-8 part, Yunnan Caulis Spatholobi 3-6 part.Also disclose the preparation method of this Chinese medicine preparation, the Chinese medicine preparation for the treatment of female climacteric syndrome of the present invention is pure Chinese medicinal preparation, has significant curative effect, without obvious toxic-side effects to the female climacteric syndrome caused by endocrine disturbance; The medicine overcoming traditional treatment climacteric syndrome uses estrogen or calm class medicine of calming the nerves in a large number, and cost is higher, the problem that life-time service is larger to human body side effect; Instant effect, determined curative effect, medicine source is extensive, with low cost.

Description

A kind of Chinese medicine preparation for the treatment of female climacteric syndrome
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of female climacteric syndrome.
Background technology
Climacteric syndrome refers to because hormonal system disequilibrium causes estrogen secretion to reduce before and after postmenopausal women, a series of body caused thus and psychic symptoms.In recent years due to the increase of life, operating pressure, its age of onset shifts to an earlier date to some extent, and sickness rate is in the trend raised year by year; The symptom of climacteric women is obvious, and patient has born heavy stress, has had a strong impact on the harmony of family life.
Chinese medicine is thought, kidney is " the congenital foundation ", and it hides congenital essence, constantly supplementing again by acquired essence, kidney essense is the material base of kidney yang, kidney yin, and the negative and positive of kidney to be internal organs negative and positive basic, i.e. so-called kidney " hide Kidney-Yin, residence Yuanyang ", imbalance of YIN and YANG then climacteric all diseases do.The negative and positive of conditioning viscera are the keys of this disease for the treatment of, and the negative and positive of conditioning kidney are primary points of penetration.
At present climacteric syndrome many employings complementing estrogen is treated or taken and there is calm effect class medicine of calming the nerves, but its clinical symptoms improvement rate is unsatisfactory, and long-term taking also has certain toxic and side effects to health.
Summary of the invention
The object of the invention is for overcoming above-mentioned the deficiencies in the prior art, to provide a kind of good effect, the Chinese medicine preparation of the treatment female climacteric syndrome of safe without toxic side effect.
For achieving the above object, the present invention adopts following technical proposals:
Treat a Chinese medicine preparation for female climacteric syndrome, be made up of the crude drug of following weight portion:
Radix Angelicae Sinensis 18-24 part, Radix Paeoniae Alba 15-20 part, Radix Rehmanniae Preparata 15-20 part, Radix Scutellariae 15-20 part, Rhizoma Chuanxiong 12-16 part, Fructus Corni 12-16 part, Radix Glycyrrhizae 8-12 part, Radix Chloranthi Serrati 5-10 part, Herba chloranthi japonici 5-10 part, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 5-10 part, Flos Campsis 5-10 part, Herba Silenes conoideae 5-10 part, Aquilegia yabeana 4-8 part, Herba Pyrolae 4-8 part, Yunnan Caulis Spatholobi 3-6 part.
The Chinese medicine preparation for the treatment of female climacteric syndrome of the present invention, preferred prescription is:
Radix Angelicae Sinensis 20 parts, the Radix Paeoniae Alba 18 parts, Radix Rehmanniae Preparata 18 parts, Radix Scutellariae 16 parts, Rhizoma Chuanxiong 14 parts, Fructus Corni 14 parts, 10 parts, Radix Glycyrrhizae, Radix Chloranthi Serrati 8 parts, Herba chloranthi japonici 8 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 8 parts, Flos Campsis 6 parts, Herba Silenes conoideae 6 parts, Aquilegia yabeana 6 parts, Herba Pyrolae 6 parts, Yunnan Caulis Spatholobi 4 parts.
Formula of the present invention is according to China theory of TCM, in conjunction with inventor's clinical research for many years, the macroscopic syndrome of Chinese medicine opinion is controlled and the Empirical formula that draws in the refined diagnosis Technology application of modern medicine to clinical experimentation.According to theory of Chinese medical science, for the pathogeny that climacteric is comprehensive, carry out dialectical composition of prescription, the negative and positive basing oneself upon internal organs regulate, to reach the object for the treatment of both the principal and secondary aspects of a disease.
In medicament composing prescription, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Scutellariae, Rhizoma Chuanxiong, Fructus Corni, Radix Glycyrrhizae, Flos Campsis, Herba Pyrolae, Yunnan Caulis Spatholobi 10 taste medical material is the kind that " Chinese Pharmacopoeia " 2010 version () is recorded, every regulation that its quality is relevant under all meeting each kind item; Radix Chloranthi Serrati, Herba chloranthi japonici, Herba Silenes conoideae, Aquilegia yabeana 4 taste medical material is the kind that " Shandong medicinal plants " (Shandong science tech publishing house, version in 1998) is recorded, every regulation that its quality is relevant under all meeting each kind item; The kind that Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) records for " genuine medicinal materials figure allusion quotation " (Fujian science tech publishing house), every regulation that its quality is relevant under all meeting this kind item.
Wherein, Radix Angelicae Sinensis: having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
The Radix Paeoniae Alba: there is nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, effect of suppressing liver-YANG.For blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, limb pain twin, has a headache dizzy.
Radix Rehmanniae Preparata: have YIN nourishing of enriching blood, beneficial essence fills out effect of marrow.For blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, dizzy, tinnitus, early whitening of beard and hair.
Radix Scutellariae: there is heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive effect.For hygropyrexia, heat-damp in summer, vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Rhizoma Chuanxiong: there is blood-activating and qi-promoting, effect of wind-expelling pain-stopping.For obstruction of qi in the chest and cardialgia, the twinge of the breast side of body, tumbling and swelling, menoxenia, amenorrhea dysmenorrhea , mass in the abdomen is suffered from abdominal pain, headache, rheumatic arthralgia.
Fructus Corni: there is liver and kidney tonifying, effect of arresting collape syndrome by astringents.For dizzy ear toot, soreness of waist and knee joint, enuresis frequent micturition, bleeding not during menses, profuse sweating collapse, interior-heat is quenched one's thirst.
Radix Glycyrrhizae: there is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription.
Radix Chloranthi Serrati: the effect with anti-inflammation, relieving cough and resolving phlegm, relaxing muscles and tendons and activating QI and blood in the collateral, dispel the wind analgesia, removing toxic substances and promoting subsidence of swelling.
Herba chloranthi japonici: there is cold expelling, dispel the wind, clots absorbing, removing toxic substances effect, can be used for cough due to wind and cold, women's amenorrhea.
Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati): cool in nature, sweet in the mouth, pungent.Have promoting blood flow to regulate menstruation, effect of dissipating blood stasis hemostasis, for diseases such as hypertension, menoxenia, bones and muscles injury.
Flos Campsis: sweet in the mouth, acid, cold.Return liver, pericardium channel.There is promoting blood circulation to restore menstrual flow, effect of cooling blood, expelling wind.For menoxenia, amenorrhea and mass in the abdomen, puerperal swelling of the breast, rubella is rubescent, skin pruritus, acne.
Herba Silenes conoideae: have yin nourishing, invigorates blood circulation, effect of regulating menstruation; For cough due to consumptive disease, menoxenia.
Aquilegia yabeana: there is heat-clearing and toxic substances removing, effect of regulating menstruation, hemostasis; Can be used for menoxenia, dysmenorrhea, puerperal, congestion was too much.
Herba Pyrolae: there is wind-damp dispelling, bone and muscle strengthening, hemostasis, effect of cough-relieving.For rheumatic arthralgia, lumbago due to renal deficiency, weakness of the waist and knees, menorrhagia, chronic cough due to asthenia of viscera.
Yunnan Caulis Spatholobi: there is blood circulation promoting and enriching, menstruction regulating and pain relieving, effect of channels sootheing and network vessel quickening.For menoxenia, dysmenorrhea, paralysis and numbness, rheumatic arthralgia, deficient qi and blood.
In medicament composing prescription of the present invention, each drug component is through dialectical compatibility, and in drug action, mutually assistant helps, and plays strengthening the body resistance altogether, effect that nourishing the liver and kidney, promoting blood flow to regulate menstruation, relieving restlessness are calmed the nerves, fundamentally realizes treating both the principal and secondary aspects of a disease to female climacteric syndrome.
Chinese medicine preparation of the present invention can adopt following methods to prepare:
(1) take each Chinese medicinal components by parts by weight in prescription, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), Flos Campsis 2 taste medicine be dry, pulverize, cross 200-300 mesh sieve, obtain medicinal powder, for subsequent use;
(2) by Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Scutellariae, Rhizoma Chuanxiong, Fructus Corni, Radix Glycyrrhizae, Radix Chloranthi Serrati, Herba chloranthi japonici, Herba Silenes conoideae, Aquilegia yabeana, Herba Pyrolae, the mixing of Yunnan Caulis Spatholobi 13 taste medicine, soak by water 2 times, add the water of 8-10 times amount for the first time, decoct 2-4 hour; Second time adds the water of 6-8 times amount, and decoct 1-2 hour, merge the decoction liquor of twice and filter, filtrate reduced in volume, recording relative density when being concentrated into 60 DEG C is 1.15-1.25, obtains extractum;
(3) the extractum mixing that medicinal powder step (1) obtained and step (2) obtain, dry, to obtain final product.
The Chinese medicine preparation for the treatment of female climacteric syndrome of the present invention can make the dosage form medically approved, according to a conventional method as capsule, tablet or granule.
Beneficial effect of the present invention:
(1) Chinese medicine preparation for the treatment of female climacteric syndrome of the present invention is pure Chinese medicinal preparation, has significant curative effect, without obvious toxic-side effects to the female climacteric syndrome caused by endocrine disturbance; The medicine overcoming traditional treatment climacteric syndrome uses estrogen or calm class medicine of calming the nerves in a large number, and cost is higher, the problem that life-time service is larger to human body side effect;
(2) instant effect, determined curative effect, medicine source is extensive, with low cost;
Detailed description of the invention
Below by instantiation, the present invention will be further elaborated, should be noted that following explanation is only to explain the present invention, not limits its content.
Embodiment 1 one kinds treats the Chinese medicine preparation of female climacteric syndrome
[prescription] Radix Angelicae Sinensis 20 kilograms, the Radix Paeoniae Alba 18 kilograms, Radix Rehmanniae Preparata 18 kilograms, Radix Scutellariae 16 kilograms, Rhizoma Chuanxiong 14 kilograms, Fructus Corni 14 kilograms, 10 kilograms, Radix Glycyrrhizae, Radix Chloranthi Serrati 8 kilograms, Herba chloranthi japonici 8 kilograms, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 8 kilograms, Flos Campsis 6 kilograms, Herba Silenes conoideae 6 kilograms, Aquilegia yabeana 6 kilograms, Herba Pyrolae 6 kilograms, Yunnan Caulis Spatholobi 4 kilograms.
[method for making] (1) takes each Chinese medicinal components by parts by weight in prescription, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), Flos Campsis 2 taste medicine be dry, pulverize, and crosses 300 mesh sieves, obtains medicinal powder, for subsequent use;
(2) by Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Scutellariae, Rhizoma Chuanxiong, Fructus Corni, Radix Glycyrrhizae, Radix Chloranthi Serrati, Herba chloranthi japonici, Herba Silenes conoideae, Aquilegia yabeana, Herba Pyrolae, the mixing of Yunnan Caulis Spatholobi 13 taste medicine, soak by water 2 times, add the water of 9 times amount (ml/g) for the first time, decoct 3 hours; Second time adds the water of 7 times amount (ml/g), and decoct 1.5 hours, merge the decoction liquor of twice and filter, filtrate reduced in volume, recording relative density when being concentrated into 60 DEG C is 1.2, obtains extractum;
(3) mixing of extractum that medicinal powder step (1) obtained and step (2) obtain, 65 DEG C of dryings 5 hours, to obtain final product.
The Chinese medicine preparation of the present embodiment can make the capsule medically approved according to a conventional method, and the specification of capsule is 0.25g/ grain, and usage and dosage is: every day 3 times, each 4.
Embodiment 2 one kinds treats the Chinese medicine preparation of female climacteric syndrome
[prescription] Radix Angelicae Sinensis 18 kilograms, the Radix Paeoniae Alba 20 kilograms, Radix Rehmanniae Preparata 15 kilograms, Radix Scutellariae 20 kilograms, Rhizoma Chuanxiong 12 kilograms, Fructus Corni 16 kilograms, 8 kilograms, Radix Glycyrrhizae, Radix Chloranthi Serrati 10 kilograms, Herba chloranthi japonici 5 kilograms, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 10 kilograms, Flos Campsis 5 kilograms, Herba Silenes conoideae 10 kilograms, Aquilegia yabeana 4 kilograms, Herba Pyrolae 8 kilograms, Yunnan Caulis Spatholobi 3 kilograms.
[method for making] (1) takes each Chinese medicinal components by parts by weight in prescription, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), Flos Campsis 2 taste medicine be dry, pulverize, and crosses 300 mesh sieves, obtains medicinal powder, for subsequent use;
(2) by Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Scutellariae, Rhizoma Chuanxiong, Fructus Corni, Radix Glycyrrhizae, Radix Chloranthi Serrati, Herba chloranthi japonici, Herba Silenes conoideae, Aquilegia yabeana, Herba Pyrolae, the mixing of Yunnan Caulis Spatholobi 13 taste medicine, soak by water 2 times, add the water of 10 times amount (ml/g) for the first time, decoct 2 hours; Second time adds the water of 8 times amount (ml/g), and decoct 1 hour, merge the decoction liquor of twice and filter, filtrate reduced in volume, recording relative density when being concentrated into 60 DEG C is 1.25, obtains extractum;
(3) mixing of extractum that medicinal powder step (1) obtained and step (2) obtain, 65 DEG C of dryings 5 hours, to obtain final product.
The Chinese medicine preparation of the present embodiment can make the capsule medically approved according to a conventional method, and the specification of capsule is 0.25g/ grain, and usage and dosage is: every day 3 times, each 4.
Embodiment 3 one kinds treats the Chinese medicine preparation of female climacteric syndrome
[prescription] Radix Angelicae Sinensis 24 kilograms, the Radix Paeoniae Alba 15 kilograms, Radix Rehmanniae Preparata 20 kilograms, Radix Scutellariae 15 kilograms, Rhizoma Chuanxiong 16 kilograms, Fructus Corni 12 kilograms, 12 kilograms, Radix Glycyrrhizae, Radix Chloranthi Serrati 5 kilograms, Herba chloranthi japonici 10 kilograms, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 5 kilograms, Flos Campsis 10 kilograms, Herba Silenes conoideae 5 kilograms, Aquilegia yabeana 8 kilograms, Herba Pyrolae 4 kilograms, Yunnan Caulis Spatholobi 6 kilograms.
[method for making] (1) takes each Chinese medicinal components by parts by weight in prescription, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), Flos Campsis 2 taste medicine be dry, pulverize, and crosses 200 mesh sieves, obtains medicinal powder, for subsequent use;
(2) by Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Scutellariae, Rhizoma Chuanxiong, Fructus Corni, Radix Glycyrrhizae, Radix Chloranthi Serrati, Herba chloranthi japonici, Herba Silenes conoideae, Aquilegia yabeana, Herba Pyrolae, the mixing of Yunnan Caulis Spatholobi 13 taste medicine, soak by water 2 times, add the water of 8 times amount (ml/g) for the first time, decoct 4 hours; Second time adds the water of 6 times amount (ml/g), and decoct 2 hours, merge the decoction liquor of twice and filter, filtrate reduced in volume, recording relative density when being concentrated into 60 DEG C is 1.15, obtains extractum;
(3) mixing of extractum that medicinal powder step (1) obtained and step (2) obtain, 65 DEG C of dryings 5 hours, to obtain final product.
The Chinese medicine preparation of the present embodiment can make the capsule medically approved according to a conventional method, and the specification of capsule is 0.25g/ grain, and usage and dosage is: every day 3 times, each 4.
Clinical data
One, physical data:
Chinese medicine preparation of the present invention be applied to clinical observation case 60 example, be women, age 40-55 year.
Two, diagnostic criteria and criterion of therapeutical effect:
(1) diagnostic criteria: " the new Chinese medicine treatment female climacteric syndrome guideline of clinical investigations " issued according to Ministry of Public Health.Clinical manifestation is: menoxenia, and hectic fever is flushing, warms sweating, irritable, palpitation and insomnia, and head uncomfortable in chest adds, abnormal emotion-thought, hypomnesis etc.
(2) curative effect determinate standard
Formulate with reference to the curative effect determinate standard in " new Chinese medicine treatment female climacteric syndrome guideline of clinical investigations ".
1. effective: clinical symptoms reduces more than 90%, and physico-chemical examination result returns to respective horizontal, and continue more than 6 months nothings repeatedly;
2. effective: clinical symptoms reduces 30-90%, and physico-chemical examination result makes moderate progress, and without repeatedly in 6 months;
3. invalid: clinical symptoms reduces less than 30%, physical and chemical index is without improvement or worsen.
Three, clinical testing procedure:
(1) case grouping
Selected case history is divided at random test group 30 example, matched group 30 example.
(2) dosage regimen
Test group takes capsule prepared by the embodiment of the present invention 1, oral, every day 3 times, each 4; Matched group takes Kuntai capsule (Guiyang Xintian Pharmaceutical Industry Co., Ltd., the accurate word of traditional Chinese medicines: Z20000083), oral, every day 3 times, each 4; Within 30 days, be a course for the treatment of, observe 3 courses for the treatment of.
Four, clinical treatment outcome and model case
(1) clinical therapeutic efficacy
The therapeutic effect of test group and matched group is in table 1.Result shows, the overall clinical efficacy rate of test group is 93.0%, is better than matched group.Show Chinese medicine composition determined curative effect of the present invention.
Table 1. test group and matched group comparitive study
(2) model case:
Case 1, Tan, female, 43 years old, medical the first half starts to occur menoxenia, and with warming sweating, irritable, palpitation and insomnia, head uncomfortable in chest such as to add at the symptom, is diagnosed as climacteric syndrome through tcm diagnosis, after 1 course for the treatment of of Chinese medicine preparation adopting the embodiment of the present invention 1 to prepare, symptom is clearly better, and after continuing to take 2 courses for the treatment of, cures, follow up a case by regular visits to 1 year, have no recurrence.
Case 2, virgin so-and-so, female, 51 years old, go to a doctor and start to occur chest distress and palpitation symptoms for first 3 months, abnormal emotion-thought, the symptoms such as hypomnesis, are diagnosed as climacteric syndrome through tcm diagnosis, after 2 courses for the treatment of of Chinese medicine preparation adopting the embodiment of the present invention 1 to prepare, symptom obviously alleviates, and after continuing to take 1 course for the treatment of, cures, follow up a case by regular visits to 1 year, have no recurrence.

Claims (3)

1. treat a Chinese medicine preparation for female climacteric syndrome, it is characterized in that, be made up of the crude drug of following weight portion:
Radix Angelicae Sinensis 18-24 part, Radix Paeoniae Alba 15-20 part, Radix Rehmanniae Preparata 15-20 part, Radix Scutellariae 15-20 part, Rhizoma Chuanxiong 12-16 part, Fructus Corni 12-16 part, Radix Glycyrrhizae 8-12 part, Radix Chloranthi Serrati 5-10 part, Herba chloranthi japonici 5-10 part, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 5-10 part, Flos Campsis 5-10 part, Herba Silenes conoideae 5-10 part, Aquilegia yabeana 4-8 part, Herba Pyrolae 4-8 part, Yunnan Caulis Spatholobi 3-6 part.
2. a kind of Chinese medicine preparation for the treatment of female climacteric syndrome as claimed in claim 1, is characterized in that, be made up of the crude drug of following weight portion:
Radix Angelicae Sinensis 20 parts, the Radix Paeoniae Alba 18 parts, Radix Rehmanniae Preparata 18 parts, Radix Scutellariae 16 parts, Rhizoma Chuanxiong 14 parts, Fructus Corni 14 parts, 10 parts, Radix Glycyrrhizae, Radix Chloranthi Serrati 8 parts, Herba chloranthi japonici 8 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 8 parts, Flos Campsis 6 parts, Herba Silenes conoideae 6 parts, Aquilegia yabeana 6 parts, Herba Pyrolae 6 parts, Yunnan Caulis Spatholobi 4 parts.
3. the preparation method of the Chinese medicine preparation of the treatment female climacteric syndrome described in claim 1 or 2, is characterized in that, comprise the following steps:
(1) take each Chinese medicinal components by parts by weight in prescription, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), Flos Campsis 2 taste medicine be dry, pulverize, cross 200-300 mesh sieve, obtain medicinal powder, for subsequent use;
(2) by Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Scutellariae, Rhizoma Chuanxiong, Fructus Corni, Radix Glycyrrhizae, Radix Chloranthi Serrati, Herba chloranthi japonici, Herba Silenes conoideae, Aquilegia yabeana, Herba Pyrolae, the mixing of Yunnan Caulis Spatholobi 13 taste medicine, soak by water 2 times, add the water of 8-10 times amount for the first time, decoct 2-4 hour; Second time adds the water of 6-8 times amount, and decoct 1-2 hour, merge the decoction liquor of twice and filter, filtrate reduced in volume, recording relative density when being concentrated into 60 DEG C is 1.15-1.25, obtains extractum;
(3) the extractum mixing that medicinal powder step (1) obtained and step (2) obtain, dry, to obtain final product.
CN201410218369.XA 2014-05-22 2014-05-22 A kind of Chinese medicine preparation for the treatment of female climacteric syndrome Expired - Fee Related CN103977133B (en)

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