CN103957707A - 与女性胃轻瘫有关的症状的治疗 - Google Patents

与女性胃轻瘫有关的症状的治疗 Download PDF

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Publication number
CN103957707A
CN103957707A CN201280052214.2A CN201280052214A CN103957707A CN 103957707 A CN103957707 A CN 103957707A CN 201280052214 A CN201280052214 A CN 201280052214A CN 103957707 A CN103957707 A CN 103957707A
Authority
CN
China
Prior art keywords
metoclopramide
gastroparesis
administered
female
daily dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201280052214.2A
Other languages
English (en)
Chinese (zh)
Inventor
马修·J·多诺弗里奥
大卫·A·格尼尔
玛丽莲·R·卡尔森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evoke Pharma Inc
Original Assignee
Evoke Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evoke Pharma Inc filed Critical Evoke Pharma Inc
Publication of CN103957707A publication Critical patent/CN103957707A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201280052214.2A 2011-08-25 2012-08-23 与女性胃轻瘫有关的症状的治疗 Pending CN103957707A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161527563P 2011-08-25 2011-08-25
US61/527,563 2011-08-25
US201261583447P 2012-01-05 2012-01-05
US61/583,447 2012-01-05
PCT/US2012/052096 WO2013028882A1 (en) 2011-08-25 2012-08-23 Treatment of symptoms associated with female gastroparesis

Publications (1)

Publication Number Publication Date
CN103957707A true CN103957707A (zh) 2014-07-30

Family

ID=47746868

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280052214.2A Pending CN103957707A (zh) 2011-08-25 2012-08-23 与女性胃轻瘫有关的症状的治疗

Country Status (14)

Country Link
US (1) US20130217775A1 (https=)
EP (1) EP2747561B1 (https=)
JP (3) JP2014524478A (https=)
CN (1) CN103957707A (https=)
BR (1) BR112014004418A8 (https=)
CA (1) CA2846340A1 (https=)
DK (1) DK2747561T3 (https=)
ES (1) ES2683042T3 (https=)
MX (1) MX356317B (https=)
PL (1) PL2747561T3 (https=)
PT (1) PT2747561T (https=)
RU (1) RU2616520C2 (https=)
TR (1) TR201811221T4 (https=)
WO (1) WO2013028882A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110996961A (zh) * 2017-07-31 2020-04-10 施万生物制药研发Ip有限责任公司 利用维司曲格治疗胃轻瘫症状的方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130213393A1 (en) 2009-12-22 2013-08-22 Evoke Pharma, Inc. Nasal formulations of metoclopramide
EP3554489A4 (en) 2016-12-15 2020-06-17 Evoke Pharma, Inc. TREATMENT FROM MODERATE TO HEAVY GASTROPARESIS
WO2018191584A1 (en) * 2017-04-14 2018-10-18 The Johns Hopkins University Nutritional and therapeutic supplement compositions
EP3681573A4 (en) * 2017-09-11 2021-08-04 Evoke Pharma, Inc. METOCLOPRAMIDE METHOD OF DOSING INTRANASAL METOCLOPRAMIDE
CN113354553B (zh) * 2021-06-03 2023-09-15 北京宝诺康医药科技有限公司 一种甲氧氯普胺单盐酸盐一水合物的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020065321A1 (en) * 2000-03-30 2002-05-30 Lehman Laura S. Nasal administration of agents for the treatment of gastroparesis
US20050137265A1 (en) * 2003-03-31 2005-06-23 Haley Eugene T. Rapidly dissolving metoclopramide solid oral dosage and method thereof
WO2010075444A2 (en) * 2008-12-22 2010-07-01 Evoke Pharma, Inc. Nasal formulations of metoclopramide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL281394A (https=) 1961-07-25
US4624965A (en) 1984-11-15 1986-11-25 Nastech Pharmaceutical Co., Inc. Novel method of administering anti-nausea and anti-emetic pharmaceutical agents and novel dosage forms containing same
US5760086A (en) 1996-03-14 1998-06-02 Ribogene, Inc. Nasal administration of agents for treatment of delayed onset emesis
HUP9902891A3 (en) * 1997-03-13 2000-11-28 Ribogene Inc Hayward Intranasal administration of a metoclopramide containing spray for treatment of delayed onset emesis
US6187332B1 (en) * 1999-06-14 2001-02-13 Wisconsin Alumni Research Foundation Acidic buffered nasal spray
GB9918559D0 (en) * 1999-08-07 1999-10-06 Glaxo Wellcome Kk Novel pharmaceutical formulation
US20030044356A1 (en) * 2001-04-20 2003-03-06 Jin Auh Composition for nasal solution sprays having effective component of 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one)
US20050175679A1 (en) * 2004-02-10 2005-08-11 Michael Moshman Controlled release formulations
JP2012521412A (ja) * 2009-03-23 2012-09-13 ライラ ファーマシューティカルズ ピーブイティ．エルティディ． 鼻のアレルギー疾患において適用するためのクルクミノイドおよびその代謝物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020065321A1 (en) * 2000-03-30 2002-05-30 Lehman Laura S. Nasal administration of agents for the treatment of gastroparesis
US20050137265A1 (en) * 2003-03-31 2005-06-23 Haley Eugene T. Rapidly dissolving metoclopramide solid oral dosage and method thereof
WO2010075444A2 (en) * 2008-12-22 2010-07-01 Evoke Pharma, Inc. Nasal formulations of metoclopramide

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WO, ET AL: "Motility and Functional Disorders of the Stomach:Diagnosis and Management of Functional Dyspepsia and Gastroparesis", 《GI MOTILITY,A SERIES FROM THE AMS,SERIES #4》, 31 December 2006 (2006-12-31), pages 23 - 48, XP008173114 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110996961A (zh) * 2017-07-31 2020-04-10 施万生物制药研发Ip有限责任公司 利用维司曲格治疗胃轻瘫症状的方法

Also Published As

Publication number Publication date
ES2683042T3 (es) 2018-09-24
EP2747561A1 (en) 2014-07-02
JP6511492B2 (ja) 2019-05-15
PL2747561T3 (pl) 2018-11-30
EP2747561B1 (en) 2018-05-09
EP2747561A4 (en) 2014-12-24
TR201811221T4 (tr) 2018-08-27
MX356317B (es) 2018-05-23
BR112014004418A8 (pt) 2018-01-23
PT2747561T (pt) 2018-09-28
BR112014004418A2 (pt) 2017-03-28
DK2747561T3 (en) 2018-08-06
RU2616520C2 (ru) 2017-04-17
JP2014524478A (ja) 2014-09-22
MX2014002125A (es) 2014-10-17
CA2846340A1 (en) 2013-02-28
WO2013028882A1 (en) 2013-02-28
RU2014111070A (ru) 2015-09-27
JP2018008979A (ja) 2018-01-18
JP2019031551A (ja) 2019-02-28
US20130217775A1 (en) 2013-08-22

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20140730

RJ01 Rejection of invention patent application after publication