CN103945765B - 计算并呈现灰质中的脑部淀粉样物质的方法 - Google Patents

计算并呈现灰质中的脑部淀粉样物质的方法 Download PDF

Info

Publication number
CN103945765B
CN103945765B CN201280056202.7A CN201280056202A CN103945765B CN 103945765 B CN103945765 B CN 103945765B CN 201280056202 A CN201280056202 A CN 201280056202A CN 103945765 B CN103945765 B CN 103945765B
Authority
CN
China
Prior art keywords
image
anatomical features
interest
radioactive indicator
region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201280056202.7A
Other languages
English (en)
Chinese (zh)
Other versions
CN103945765A (zh
Inventor
F·O·蒂勒
F·文策尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Koninklijke Philips NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips NV filed Critical Koninklijke Philips NV
Publication of CN103945765A publication Critical patent/CN103945765A/zh
Application granted granted Critical
Publication of CN103945765B publication Critical patent/CN103945765B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
    • A61B5/0035—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
    • A61B5/004—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0042—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/037—Emission tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/501—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of the head, e.g. neuroimaging or craniography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
    • A61B6/5229—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data combining image data of a patient, e.g. combining a functional image with an anatomical image
    • A61B6/5247—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data combining image data of a patient, e.g. combining a functional image with an anatomical image combining images from an ionising-radiation diagnostic technique and a non-ionising radiation diagnostic technique, e.g. X-ray and ultrasound
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4808—Multimodal MR, e.g. MR combined with positron emission tomography [PET], MR combined with ultrasound or MR combined with computed tomography [CT]
    • G01R33/481—MR combined with positron emission tomography [PET] or single photon emission computed tomography [SPECT]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G06T7/0014—Biomedical image inspection using an image reference approach
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/46—Arrangements for interfacing with the operator or the patient
    • A61B6/461—Displaying means of special interest
    • A61B6/466—Displaying means of special interest adapted to display 3D data
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10088—Magnetic resonance imaging [MRI]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10104—Positron emission tomography [PET]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30016—Brain

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Optics & Photonics (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Quality & Reliability (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Nuclear Medicine (AREA)
CN201280056202.7A 2011-11-16 2012-11-13 计算并呈现灰质中的脑部淀粉样物质的方法 Expired - Fee Related CN103945765B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161560319P 2011-11-16 2011-11-16
US61/560,319 2011-11-16
PCT/IB2012/056379 WO2013072843A1 (en) 2011-11-16 2012-11-13 Method to compute and present brain amyloid in gray matter

Publications (2)

Publication Number Publication Date
CN103945765A CN103945765A (zh) 2014-07-23
CN103945765B true CN103945765B (zh) 2016-10-26

Family

ID=47459049

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280056202.7A Expired - Fee Related CN103945765B (zh) 2011-11-16 2012-11-13 计算并呈现灰质中的脑部淀粉样物质的方法

Country Status (8)

Country Link
US (1) US9585567B2 (enExample)
EP (1) EP2747658B1 (enExample)
JP (1) JP6100792B2 (enExample)
CN (1) CN103945765B (enExample)
BR (1) BR112014009039A2 (enExample)
IN (1) IN2014CN03661A (enExample)
RU (1) RU2014113912A (enExample)
WO (1) WO2013072843A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013214050A1 (de) * 2013-07-17 2015-01-22 Siemens Aktiengesellschaft Verfahren zu einem Darstellen von Bilddaten von Körperbereichen eines Patienten, wobei die Körperbereiche an einer Demenz-Erkrankung erkranken können, sowie ein medizinische Bildgebungssystem, das zu einer Ausführung des Verfahrens ausgelegt ist
US10674983B2 (en) * 2013-09-25 2020-06-09 Richard R. Black Patient-specific analysis of positron emission tomography data
JP5689205B1 (ja) * 2014-11-21 2015-03-25 日本メジフィジックス株式会社 頭部核医学画像の評価法
JP6775944B2 (ja) * 2015-12-14 2020-10-28 キヤノンメディカルシステムズ株式会社 画像処理装置
CN105816192A (zh) * 2016-03-03 2016-08-03 王雪原 个体化人脑多模态医学影像的三维配准及提取脑组织方法
KR20180077819A (ko) * 2016-12-29 2018-07-09 사회복지법인 삼성생명공익재단 뇌아밀로이드 혈관병증의 예후 예측방법
EP3387997B1 (en) * 2017-04-13 2020-02-26 Siemens Healthcare GmbH Medical imaging device and method controlling one or more parameters of a medical imaging device
KR102004964B1 (ko) * 2017-10-12 2019-07-29 전남대학교산학협력단 Pet 뇌 영상 아밀로이드 측정을 위한 부피 기반 정량지표 분석 방법 및 컴퓨터 프로그램
JP7313165B2 (ja) * 2019-03-18 2023-07-24 株式会社Erisa アルツハイマー病生存分析装置及びアルツハイマー病生存分析プログラム
KR102414974B1 (ko) * 2020-08-03 2022-06-30 사회복지법인 삼성생명공익재단 Pet-ct 영상을 이용하는 알츠하이머 질환의 진단 장치 및 이의 동작 방법
US20220067919A1 (en) * 2020-08-26 2022-03-03 GE Precision Healthcare LLC System and method for identifying a tumor or lesion in a probabilty map

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7270800B2 (en) * 2000-08-24 2007-09-18 University Of Pittsburgh Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
US6819952B2 (en) 2001-03-23 2004-11-16 The Board Of Trustees Of The Leland Stanford Junior University Magnetic resonance spectroscopic imaging method to monitor progression and treatment of neurodegenerative conditions
US8423125B2 (en) * 2004-11-09 2013-04-16 Spectrum Dynamics Llc Radioimaging
US8218835B2 (en) * 2005-08-22 2012-07-10 Dai Nippon Printing Co., Ltd. Method for assisting in diagnosis of cerebral diseases and apparatus thereof
US7929737B2 (en) * 2005-09-29 2011-04-19 General Electric Company Method and system for automatically generating a disease severity index
WO2008050226A2 (en) * 2006-10-26 2008-05-02 Ge Healthcare Limited Method and system for outlining a region in positron emission tomography studies
CA2675228A1 (en) 2007-01-30 2008-07-07 Ge Healthcare Limited Tools for aiding in the diagnosis of neurodegenerative diseases
EP2120717A1 (en) 2007-03-12 2009-11-25 National Institute of Radiological Sciences Pet visualization of amyloid-associated neuroinflammation in the brain
WO2008115593A1 (en) * 2007-03-21 2008-09-25 The University Of Montana 1-[(2'-substituted)-piperazin-1'-yl]-isoquinolines as norepinephrine transporter inhibitor therapeutics and positron emission tomography imaging agents
DE102007018630A1 (de) * 2007-04-19 2008-10-23 Siemens Ag Multimodales Bildakquisitions-, Bildverarbeitungs-, Bildarchivierungs- und Bildvisialisierungssystem zur Koregistrierung, Fusionierung, Archivierung und grafischen Visualisierung endoluminaler CT- bzw. MRT-Bilddaten mit eingeblendeten PET-, PET-CT-, SPECT- bzw. SPECT-CT-Bilddaten
DE102007034956A1 (de) * 2007-07-26 2009-02-05 Siemens Ag Verfahren zum Detektieren einer neuropathologisch veränderten Gehirnregion
US7989630B2 (en) * 2008-04-30 2011-08-02 National Institutes Of Health Represented By The Secretary Of The Department Of Health And Human Services, National Institutes Of Health Radiotracers for imaging P-glycoprotein function
WO2009146388A1 (en) * 2008-05-28 2009-12-03 The Trustees Of Columbia University In The City Of New York Voxel-based methods for assessing subjects using positron emission tomography
CN102317975B (zh) * 2009-02-17 2015-02-04 皇家飞利浦电子股份有限公司 功能成像
CN102395999B (zh) * 2009-04-15 2014-08-20 皇家飞利浦电子股份有限公司 医学图像数据的量化
SG2014012686A (en) 2009-10-08 2014-06-27 Ge Healthcare Ltd Purification method
EP2538982A4 (en) 2010-02-25 2016-02-17 Janssen Alzheimer Immunotherap PET MONITORING OF IMMUNOTHERAPY TARGETED ON A-BETA
WO2012051170A2 (en) * 2010-10-12 2012-04-19 Mayo Foundation For Medical Education And Research Imaging of meningiomas using phingylbenzothiazole, stilbene, or biphenylalkyne derivatives
US9271652B2 (en) * 2011-03-07 2016-03-01 Koninklijke Philips N.V. MR segmentation using nuclear emission data in hybrid nuclear imaging/MR
US9002081B2 (en) * 2011-10-18 2015-04-07 Matthew Sherman Brown Computer-aided bone scan assessment with automated lesion detection and quantitative assessment of bone disease burden changes

Also Published As

Publication number Publication date
EP2747658B1 (en) 2020-01-15
JP2015502535A (ja) 2015-01-22
IN2014CN03661A (enExample) 2015-10-16
WO2013072843A1 (en) 2013-05-23
BR112014009039A2 (pt) 2017-05-09
RU2014113912A (ru) 2015-10-20
JP6100792B2 (ja) 2017-03-22
CN103945765A (zh) 2014-07-23
US9585567B2 (en) 2017-03-07
EP2747658A1 (en) 2014-07-02
US20140257084A1 (en) 2014-09-11

Similar Documents

Publication Publication Date Title
CN103945765B (zh) 计算并呈现灰质中的脑部淀粉样物质的方法
US11696701B2 (en) Systems and methods for estimating histological features from medical images using a trained model
Catana et al. Toward implementing an MRI-based PET attenuation-correction method for neurologic studies on the MR-PET brain prototype
JP5424902B2 (ja) Ｐｅｔ／ｍｒフロー推定を用いて補われる自動診断及び自動整列
Wood et al. Left ventricular ejection fraction and volumes: it depends on the imaging method
Arata et al. Three-dimensional anatomical model-based segmentation of MR brain images through principal axes registration
CN103282940B (zh) 不对称性的自动量化
AU2009337516B2 (en) Image based clinical trial assessment
EP2577604B1 (en) Processing system for medical scan images
Cabello et al. Comparison between MRI-based attenuation correction methods for brain PET in dementia patients
EP2814395B1 (en) Spatially corrected nuclear image reconstruction
US20110194741A1 (en) Brain ventricle analysis
Raniga et al. Automated 11C-PiB standardized uptake value ratio
US11495346B2 (en) External device-enabled imaging support
Corouge et al. Arterial Spin Labeling at 3T in semantic dementia: perfusion abnormalities detection and comparison with FDG-PET
Efthimiou et al. Tangible advantages of multi-stage brain motion compensation for PET imaging demonstrated in multiple studies
CN119904847A (zh) 获取医学成像设备的使用信息的方法、装置和系统
Lima Optimization of an Analysis Process of PET with PiB in Alzheimer's Disease
Lee et al. Computer-aided evaluation system for Parkinson's disease using image registration and labeling
Hult Segmentation and Visualisation of Human Brain Structures
Kudo et al. Image processing method for analyzing cerebral blood-flow using SPECT and MRI
Nichols et al. Automated versus manual detection of left ventricular wall motion abnormalities by gated blood pool SPECT

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20161026

Termination date: 20201113

CF01 Termination of patent right due to non-payment of annual fee