CN103930563B - 用于预测癌症复发的方法和装置 - Google Patents

用于预测癌症复发的方法和装置 Download PDF

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Publication number
CN103930563B
CN103930563B CN201280038428.4A CN201280038428A CN103930563B CN 103930563 B CN103930563 B CN 103930563B CN 201280038428 A CN201280038428 A CN 201280038428A CN 103930563 B CN103930563 B CN 103930563B
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mir
hsa
cancer
biomarkers
sample
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CN103930563A (zh
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S.克努森
W.梅津
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Allarity Therapeutics AS
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Medical Prognosis Institute AS
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201280038428.4A 2011-06-01 2012-06-01 用于预测癌症复发的方法和装置 Expired - Fee Related CN103930563B (zh)

Applications Claiming Priority (3)

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DKPA201100416 2011-06-01
DKPA201100416 2011-06-01
PCT/EP2012/002332 WO2012163541A1 (en) 2011-06-01 2012-06-01 Methods and devices for prognosis of cancer relapse

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CN103930563A CN103930563A (zh) 2014-07-16
CN103930563B true CN103930563B (zh) 2016-11-09

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US (1) US20140106986A1 (enExample)
EP (1) EP2714927B1 (enExample)
JP (1) JP6039656B2 (enExample)
CN (1) CN103930563B (enExample)
AU (1) AU2012265177B2 (enExample)
CA (1) CA2836836A1 (enExample)
WO (1) WO2012163541A1 (enExample)

Cited By (1)

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US20240404707A1 (en) * 2021-09-02 2024-12-05 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Machine learning-based systems and methods for predicting liver cancer recurrence in liver transplant patients

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WO2011135459A2 (en) 2010-04-29 2011-11-03 Medical Prognosis Institute A/S Methods and devices for predicting treatment efficacy
US10392667B2 (en) 2013-06-07 2019-08-27 Medical Prognosis Institute A/S Methods and devices for predicting treatment efficacy of fulvestrant in cancer patients
CN103740845B (zh) * 2014-01-28 2016-04-13 厦门大学附属中山医院 基于AllGlo探针荧光定量PCR的hsa-miR-513b检测试剂盒及其检测方法
ES2886204T3 (es) * 2014-06-24 2021-12-16 Procept Biorobotics Corp Aparato de muestreo de tejidos y tratamiento del cáncer
WO2016046640A2 (en) 2014-09-26 2016-03-31 Medical Prognosis Institute A/S Methods for predicting drug responsiveness
US20190071730A9 (en) * 2015-07-21 2019-03-07 Guardant Health, Inc. Locked nucleic acids for capturing fusion genes
US9725769B1 (en) 2016-10-07 2017-08-08 Oncology Venture ApS Methods for predicting drug responsiveness in cancer patients
AU2017258901A1 (en) 2016-12-30 2018-07-19 Allarity Therapeutics Europe ApS Methods for predicting drug responsiveness in cancer patients
AU2018202878A1 (en) 2017-05-16 2018-12-06 Allarity Therapeutics Europe ApS Methods for predicting drug responsiveness in cancer patients
CN109971851A (zh) * 2019-01-22 2019-07-05 宁波大学 MiR-125b-2-3p作为鉴别诊断肾癌亚型的分子标志物及其在肿瘤转移中的用途
JP7299765B2 (ja) * 2019-06-14 2023-06-28 株式会社東芝 マイクロｒｎａ測定方法およびキット
CN110079603A (zh) * 2019-06-14 2019-08-02 福建省肿瘤医院（福建省肿瘤研究所、福建省癌症防治中心） 一种鼻咽癌标志物的检测引物、探针及其应用
CN110408706B (zh) * 2019-08-30 2023-04-11 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） 一种评估鼻咽癌复发的生物标志物及其应用
CN111554402A (zh) * 2020-04-24 2020-08-18 山东省立医院 基于机器学习的原发性肝癌术后复发风险预测方法及系统
CN111564177B (zh) * 2020-05-22 2023-03-31 四川大学华西医院 基于dna甲基化的早期非小细胞肺癌复发模型构建方法
CN111778341B (zh) * 2020-07-28 2023-07-04 广东医科大学 一种活动性肺结核的生物标志物及其应用
CN115261464A (zh) * 2021-07-06 2022-11-01 西北工业大学 一组消化道泛癌诊疗用mRNA靶点
CN114990229B (zh) * 2022-06-20 2023-01-03 广东医科大学附属医院 一种嗜碱性粒细胞活化相关的生物标志物及其应用

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Cited By (1)

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Publication number Priority date Publication date Assignee Title
US20240404707A1 (en) * 2021-09-02 2024-12-05 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Machine learning-based systems and methods for predicting liver cancer recurrence in liver transplant patients

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Publication number Publication date
JP2014516543A (ja) 2014-07-17
JP6039656B2 (ja) 2016-12-07
CN103930563A (zh) 2014-07-16
EP2714927B1 (en) 2016-08-10
US20140106986A1 (en) 2014-04-17
EP2714927A1 (en) 2014-04-09
AU2012265177B2 (en) 2017-03-02
CA2836836A1 (en) 2012-12-06
WO2012163541A1 (en) 2012-12-06

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