CN103920017B - A kind of pharmaceutical composition treating cervicitis - Google Patents
A kind of pharmaceutical composition treating cervicitis Download PDFInfo
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- CN103920017B CN103920017B CN201410195831.9A CN201410195831A CN103920017B CN 103920017 B CN103920017 B CN 103920017B CN 201410195831 A CN201410195831 A CN 201410195831A CN 103920017 B CN103920017 B CN 103920017B
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- 206010008323 cervicitis Diseases 0.000 title claims abstract description 27
- 208000006374 Uterine Cervicitis Diseases 0.000 title claims abstract description 25
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 23
- 241000218176 Corydalis Species 0.000 claims abstract description 13
- 235000009926 Dioscorea panthaica Nutrition 0.000 claims abstract description 13
- 241000374766 Dioscorea panthaica Species 0.000 claims abstract description 13
- 241000628997 Flos Species 0.000 claims abstract description 13
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 13
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 239000003814 drug Substances 0.000 claims description 20
- 239000000706 filtrate Substances 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 229940079593 drug Drugs 0.000 claims description 8
- 239000012467 final product Substances 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 6
- 238000002360 preparation method Methods 0.000 claims description 6
- 239000002775 capsule Substances 0.000 claims description 4
- 239000012141 concentrate Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims 3
- 230000035876 healing Effects 0.000 abstract description 8
- 230000028327 secretion Effects 0.000 abstract description 4
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract description 3
- 210000003679 cervix uteri Anatomy 0.000 abstract description 2
- 210000000589 cicatrix Anatomy 0.000 abstract description 2
- 230000005906 menstruation Effects 0.000 abstract description 2
- 231100000957 no side effect Toxicity 0.000 abstract description 2
- 238000002651 drug therapy Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 230000002159 abnormal effect Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 206010061218 Inflammation Diseases 0.000 description 3
- 208000003251 Pruritus Diseases 0.000 description 3
- 230000003628 erosive effect Effects 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 201000003988 chronic cervicitis Diseases 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 230000007803 itching Effects 0.000 description 2
- 239000008921 jie er yin Substances 0.000 description 2
- 230000003821 menstrual periods Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000000554 physical therapy Methods 0.000 description 2
- 230000000306 recurrent effect Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- 210000001215 vagina Anatomy 0.000 description 2
- 206010065019 Coital bleeding Diseases 0.000 description 1
- 206010011469 Crying Diseases 0.000 description 1
- 208000008350 Pruritus Vulvae Diseases 0.000 description 1
- 206010061926 Purulence Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010056530 Vulvovaginal pruritus Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 206010000210 abortion Diseases 0.000 description 1
- 231100000176 abortion Toxicity 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000003756 cervix mucus Anatomy 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000002262 irrigation Effects 0.000 description 1
- 238000003973 irrigation Methods 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 210000004705 lumbosacral region Anatomy 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 238000001050 pharmacotherapy Methods 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000002893 slag Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 230000005186 women's health Effects 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a kind of pharmaceutical composition treating cervicitis, it is made up of the raw material of following weight: 7 15 parts of Poria, Fructus Lycii 10 19 parts, Dioscorea panthaica Prain et Burkill 38 parts, Herba Corydalis Bungeanae 12 18 parts, Glechota longituba (Nakai) Kupr 15 20 parts, Herba Saussureae Involueratae 15 20 parts, Flos Rosae Chinensis 20 40 parts, Herba Dendrobii 8 15 parts, Radix Dipsaci 15 20 parts, Rhizoma Ligustici 15 25 parts, Fructus Evodiae 10 14 parts.This Drug therapy cervicitis short treating period, healing time is fast, evident in efficacy；The secretions that other naturopathy can be avoided to cause oozes out, and drug withdrawal to menstruation next time is restorability life the most afterwards, and patient is acceptant；Soft through following up a case by regular visits to the cervix uteri matter of healing, good springiness, have no side effect without cicatrix.
Description
Technical field
The invention belongs to technical field of Chinese medicines, particularly relate to a kind of pharmaceutical composition treating cervicitis.
Background technology
Various gynecological inflammations are that sickness rate is the highest in all gynaecopathias, wherein, chronic cervicitis is exactly modal frequently-occurring disease, show that most women is suffering from gynecological inflammation according to clinically relevant data, the women of about 70% once suffered from chronic cervicitis and recurrent exerbation is difficult to cure and with symptoms such as soreness of waist and knee, weak all over, refreshing lathers, and gynecological inflammation recurrent exerbation even also results in generation serious threat women's health and the life of other pathological changes.
Gynaecopathia have become as be hidden in women body a killer, be also the most obscure disease, mostly because not noting menstrual period and health in puerperal or sexual life is unclean causes.The method treating this disease at present has physiotherapy and pharmacotherapy, and it is bigger that physiotherapy is not easy operation damage.Western medicine take effect ratio comparatively fast, but treatment is thorough, easily recurs after drug withdrawal.Chinese medicine, to be administered orally, takes effect slow, and curative effect is unsatisfactory.
Summary of the invention
For above-mentioned the deficiencies in the prior art, it is an object of the invention to provide a kind of pharmaceutical composition treating cervicitis, this courses of pharmaceuticals is short, and healing time is fast, controls difficulty in relapse after healing.
For realizing above-mentioned technical purpose, the present invention is achieved by the following technical solutions:
A kind of pharmaceutical composition treating cervicitis, it is made up of the raw material of following weight: Poria 7-15 part, Fructus Lycii 10-19 part, Dioscorea panthaica Prain et Burkill 3-8 part, Herba Corydalis Bungeanae 12-18 part, Glechota longituba (Nakai) Kupr 15-20 part, Herba Saussureae Involueratae 15-20 part, Flos Rosae Chinensis 20-40 part, Herba Dendrobii 8-15 part, Radix Dipsaci 15-20 part, Rhizoma Ligustici 15-25 part, Fructus Evodiae 10-14 part.
Preferably, a kind of pharmaceutical composition treating cervicitis, it is made up of the raw material of following weight: Poria 9-13 part, Fructus Lycii 15-18 part, Dioscorea panthaica Prain et Burkill 5-7 part, Herba Corydalis Bungeanae 14-17 part, Glechota longituba (Nakai) Kupr 17-19 part, Herba Saussureae Involueratae 16-18 part, Flos Rosae Chinensis 25-35 part, Herba Dendrobii 10-13 part, Radix Dipsaci 16-18 part, Rhizoma Ligustici 19-23 part, Fructus Evodiae 10-12 part.
Preferably, a kind of pharmaceutical composition treating cervicitis, it is made up of the raw material of following weight: 10 parts of Poria, Fructus Lycii 15 parts, Dioscorea panthaica Prain et Burkill 5 parts, Herba Corydalis Bungeanae 15 parts, Glechota longituba (Nakai) Kupr 18 parts, Herba Saussureae Involueratae 18 parts, Flos Rosae Chinensis 30 parts, Herba Dendrobii 13 parts, Radix Dipsaci 18 parts, Rhizoma Ligustici 20 parts, Fructus Evodiae 12 parts.
Preferably, a kind of pharmaceutical composition treating cervicitis, it is made up of the raw material of following weight: 12 parts of Poria, Fructus Lycii 17 parts, Dioscorea panthaica Prain et Burkill 6 parts, Herba Corydalis Bungeanae 16 parts, Glechota longituba (Nakai) Kupr 18 parts, Herba Saussureae Involueratae 17 parts, Flos Rosae Chinensis 28 parts, Herba Dendrobii 12 parts, Radix Dipsaci 17 parts, Rhizoma Ligustici 21 parts, Fructus Evodiae 11 parts.
The preparation method of the pharmaceutical composition of described treatment cervicitis is: take each crude drug, mixing, adds 8-10 times amount (weight multiple) water, decocts 1-2 hour, filter to get filtrate, in medicinal residues, add the water of 4-6 times amount (weight multiple) again, decoct 1-1.5 hour, filter to get filtrate, merge twice filtrate, conventional vacuum concentrates, is dried to obtain fine powder, makes tablet or capsule, to obtain final product.
The using method of the pharmaceutical composition for the treatment of cervicitis: during use, takes out the pharmaceutical composition of a treatment cervicitis, is dissolved in 300-800mL warm water, after medicine fully dissolves, rinses affected part, once a day.
Preferably, take out the pharmaceutical composition of a treatment cervicitis during use, be dissolved in 500mL warm water, after medicine fully dissolves, rinse affected part, once a day.
Beneficial effects of the present invention:
Short treating period, healing time is fast, evident in efficacy；The secretions that other naturopathy can be avoided to cause oozes out, and drug withdrawal to menstruation next time is restorability life the most afterwards, and patient is acceptant；Soft through following up a case by regular visits to the cervix uteri matter of healing, good springiness, have no side effect without cicatrix.
Detailed description of the invention
Below in conjunction with embodiment and clinical data, the present invention is further illustrated.
Embodiment 1
Preparing a kind of pharmaceutical composition treating cervicitis, formula is: Poria 12g, Fructus Lycii 17g, Dioscorea panthaica Prain et Burkill 6g, Herba Corydalis Bungeanae 16g, Glechota longituba (Nakai) Kupr 18g, Herba Saussureae Involueratae 17g, Flos Rosae Chinensis 28g, Herba Dendrobii 12g, Radix Dipsaci 17g, Rhizoma Ligustici 21g, Fructus Evodiae 11g.
Preparation method is: take each crude drug, mixing, adds 9 times amount water, decocts 1.5 hours, filter to get filtrate, add the water of 5 times amount in medicinal residues again, decocts 1 hour, filter to get filtrate, and merges twice filtrate, and conventional vacuum concentrates, is dried to obtain fine powder, makes capsule, to obtain final product.
Embodiment 2
Preparing a kind of pharmaceutical composition treating cervicitis, formula is: Poria 12g, Fructus Lycii 17g, Dioscorea panthaica Prain et Burkill 6g, Herba Corydalis Bungeanae 16g, Glechota longituba (Nakai) Kupr 18g, Herba Saussureae Involueratae 17g, Flos Rosae Chinensis 28g, Herba Dendrobii 12g, Radix Dipsaci 17g, Rhizoma Ligustici 21g, Fructus Evodiae 11g.
Preparation method is: take each crude drug, mixing, adds 8 times amount water, decocts 2 hours, filter to get filtrate, add the water of 6 times amount in medicinal residues again, decoct 1.5 hours, filter to get filtrate, merges twice filtrate, concentrating under reduced pressure, dry to obtain fine powder, makes tablet, to obtain final product.
Embodiment 3
Preparing a kind of pharmaceutical composition treating cervicitis, formula is: Poria 7g, Fructus Lycii 10g, Dioscorea panthaica Prain et Burkill 3g, Herba Corydalis Bungeanae 12g, Glechota longituba (Nakai) Kupr 15g, Herba Saussureae Involueratae 15g, Flos Rosae Chinensis 20g, Herba Dendrobii 8g, Radix Dipsaci 15g, Rhizoma Ligustici 15g, Fructus Evodiae 10g.
Preparation method is: take each crude drug, mixing, adds 10 times amount water, decocts 1 hour, filter to get filtrate, add the water of 4 times amount in medicinal residues again, decoct 1 hour, filter to get filtrate, merges twice filtrate, concentrating under reduced pressure, dry to obtain fine powder, makes tablet, to obtain final product.
Embodiment 4
Preparing a kind of pharmaceutical composition treating cervicitis, formula is: Poria 15g, Fructus Lycii 19g, Dioscorea panthaica Prain et Burkill 8g, Herba Corydalis Bungeanae 18g, Glechota longituba (Nakai) Kupr 20g, Herba Saussureae Involueratae 20g, Flos Rosae Chinensis 40g, Herba Dendrobii 15g, Radix Dipsaci 20g, Rhizoma Ligustici 25g, Fructus Evodiae 14g.
Preparation method is: take each crude drug, mixing, adds 8 times amount water, decocts 1 hour, filter to get filtrate, add the water of 5 times amount in medicinal residues again, decoct 1 hour, filter to get filtrate, merges twice filtrate, concentrating under reduced pressure, dry to obtain fine powder, makes capsule, to obtain final product.
Clinical data:
Physical data:
It is selected in 480 examples that certain hospital accepts for medical treatment and suffers from the patient of cervicitis, and it is randomly divided into each 240 examples of patient between treatment group and observation group's sea group, observation group's patient age is in 22-46 32 years old mean age of year, it is 15.9 months that sick time reaches 9-22 the monthly average course of disease, observation group patient uses JIEERYIN XIYE therapy for treating, additionally treatment group patient age between 22-48 year the mean age at 30 years old, sick time is up to 12-24 the monthly average course of disease 16.2 months, finally treatment group and the patient age of observation group, the situation that the course of disease is general carries out having comparability between statistics post analysis difference (p > 0.05) two groups.
Diagnostic criteria:
Tcm diagnosis is all formulated with reference to " Chinese medical disease Standardization of diagnosis and curative effect ", and the standard of Western medicine diagnose is all formulated with reference to " obstetrics and gynecology ".
Therapeutic Method:
Treatment group, during use, takes out the pharmaceutical composition of a treatment cervicitis, is dissolved in 500mL warm water, after medicine fully dissolves, rinse affected part, once a day, each course for the treatment of Monday.
Matched group, patient uses conventional medicine JIEERYIN XIYE (Chengdu En Wei pharmaceutical Co. Ltd traditional Chinese medicines quasi-word Z10930008) in the course for the treatment of of one week, take medicine 10 milliliters and add that the boiled water of tepor is mixed thoroughly to 100 milliliters, it is washed out pudendum and carries drug irrigation vagina depths, once a day with irrigator.
Standard curative effect:
Treatment group and observation group patient observe its therapeutic effect after carrying out 3 courses for the treatment of of medication.Wherein, invalid: before and after patient checks, the state of an illness is not changed in, effective: itch pain, the vagina abnormal secretion thing of patient, one of which symptom transfers to normally, effective: the pain phenomenon of itching of patient is clearly better, abnormal vaginal secretions there is not, recovery from illness: the intravaginal pain transference cure abnormal secretion thing of itching of patient also disappears.
Result:
Treatment group and observation group patient are after the treatment, the overall efficiency for the treatment of group patient is 97%, recurrence rate after healing is 4.3%, the total effective rate of observation group is 78%, recurrence rate after healing is 43.3%, cure rate and the relapse rate for the treatment of group have obvious comparability (p < 0.05) between observation group two groups, are specifically shown in table 1 below.
1 liang of table group Clinical efficacy comparison [example (%)]
Clinical model case:
Case 1, river, 29 years old, married, Laiwu City people.Patient's private prosecution: cervical erosion 3 degree, in many ways seeks medical advice and the most thoroughly cures, bad during fashion, aggravation of catching a cold of catching a cold today, and leucorrhea substantially increases, and has foreign odor, faint yellow purulence, and postcoital bleeding is serious, the most once does artificial abortion.Simultaneously with symptoms such as pain in the lumbar region, the soreness of waist, urine urgency-frequencies.It is severe cervical erosion through examination in hospital, treats and do not feel any better for 3 months.2 recoveries from illness course for the treatment of of the application of the invention medicine.
Case 2, Wang, 45 years old, patient's readme: pruritus vulvae, leukorrhagia, cervical erosion, urine abnormal (not drenching), sometimes feeling of fullness in the head, dizziness, insomnia and dreamful sleep, when crying or time angry, the dizzy pain of feeling of fullness in the head, the state of an illness of seeking medical advice everywhere is not felt any better, recently pudendum seriously fester, the slag that loses flesh, swollen pain unbearably, uses medicine of the present invention to fully recover 3 courses for the treatment of.
Case 3, Zheng, 30 years old, the frequent leukorrhagia of readme, abnormal flavour, underpants must be changed every day, the most hidden pain of lower abdomen, each transfusion in menstrual period etc. is failed to respond to any medical treatment, and uses 3 recoveries from illness course for the treatment of of medicine of the present invention.
With clinical data, the detailed description of the invention of the present invention is described although above-mentioned in conjunction with the embodiments; but not limiting the scope of the invention; one of ordinary skill in the art should be understood that; on the basis of technical scheme, those skilled in the art need not to pay various amendments or deformation that creative work can make still within protection scope of the present invention.
Claims (5)
1. the pharmaceutical composition treating cervicitis, it is characterised in that be made up of the raw material of following weight: Poria 7-
15 parts, Fructus Lycii 10-19 part, Dioscorea panthaica Prain et Burkill 3-8 part, Herba Corydalis Bungeanae 12-18 part, Glechota longituba (Nakai) Kupr 15-20 part, Herba Saussureae Involueratae 15-
20 parts, Flos Rosae Chinensis 20-40 part, Herba Dendrobii 8-15 part, Radix Dipsaci 15-20 part, Rhizoma Ligustici 15-25 part, Fructus Evodiae 10-14 part.
2. the as claimed in claim 1 pharmaceutical composition treating cervicitis, it is characterised in that former by following weight
Material is made: Poria 9-13 part, Fructus Lycii 15-18 part, Dioscorea panthaica Prain et Burkill 5-7 part, Herba Corydalis Bungeanae 14-17 part, Glechota longituba (Nakai) Kupr 17-19 part,
Herba Saussureae Involueratae 16-18 part, Flos Rosae Chinensis 25-35 part, Herba Dendrobii 10-13 part, Radix Dipsaci 16-18 part, Rhizoma Ligustici 19-23 part, Wu Zhu
Cornel 10-12 part.
3. the as claimed in claim 1 pharmaceutical composition treating cervicitis, it is characterised in that former by following weight
Material is made: 10 parts of Poria, Fructus Lycii 15 parts, Dioscorea panthaica Prain et Burkill 5 parts, Herba Corydalis Bungeanae 15 parts, Glechota longituba (Nakai) Kupr 18 parts, Herba Saussureae Involueratae
18 parts, Flos Rosae Chinensis 30 parts, Herba Dendrobii 13 parts, Radix Dipsaci 18 parts, Rhizoma Ligustici 20 parts, Fructus Evodiae 12 parts.
4. the as claimed in claim 1 pharmaceutical composition treating cervicitis, it is characterised in that former by following weight
Material is made: 12 parts of Poria, Fructus Lycii 17 parts, Dioscorea panthaica Prain et Burkill 6 parts, Herba Corydalis Bungeanae 16 parts, Glechota longituba (Nakai) Kupr 18 parts, Herba Saussureae Involueratae
17 parts, Flos Rosae Chinensis 28 parts, Herba Dendrobii 12 parts, Radix Dipsaci 17 parts, Rhizoma Ligustici 21 parts, Fructus Evodiae 11 parts.
5. the preparation method of the pharmaceutical composition of the treatment cervicitis as described in claim 1-4 is arbitrary, it is characterised in that take each
Crude drug, mixing, add the water that weight multiple is 8-10 times, decoct 1-2 hour, filter to get filtrate, increase the weight of again in medicinal residues
Amount multiple is the water of 4-6 times amount, decocts 1-1.5 hour, filters to get filtrate, and merges twice filtrate, and conventional vacuum concentrates, does
Dry fine powder, makes tablet or capsule, to obtain final product.
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| CN201410195831.9A CN103920017B (en) | 2014-05-09 | 2014-05-09 | A kind of pharmaceutical composition treating cervicitis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410195831.9A CN103920017B (en) | 2014-05-09 | 2014-05-09 | A kind of pharmaceutical composition treating cervicitis |
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| CN103920017B true CN103920017B (en) | 2016-08-17 |
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| CN107412528A (en) * | 2017-08-08 | 2017-12-01 | 江西师范高等专科学校 | A kind of pill for treating cervicitis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1095610A (en) * | 1993-05-24 | 1994-11-30 | 潘世庆 | The pharmaceutical preparation Fubingkang of treatment, prevention gynecological diseases |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2799386A1 (en) * | 2010-05-18 | 2011-11-24 | Optimer Pharmaceuticals, Inc. | Treatment of clostridium difficile infection in patients undergoing antibiotic therapy |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1095610A (en) * | 1993-05-24 | 1994-11-30 | 潘世庆 | The pharmaceutical preparation Fubingkang of treatment, prevention gynecological diseases |
Non-Patent Citations (1)
| Title |
|---|
| 银草合剂治疗支原体阴道（宫颈）炎疗效观察;王砚宁等;《河南中医》;20000131;第20卷(第1期);第36页，尤其是左栏第1、6段 * |
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