CN103906736A - 作为类香草素受体配体的具有被含n-基团取代的苯基基团的被取代的基于吡唑基的羧酰胺和脲衍生物 - Google Patents
作为类香草素受体配体的具有被含n-基团取代的苯基基团的被取代的基于吡唑基的羧酰胺和脲衍生物 Download PDFInfo
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11008913 | 2011-11-09 | ||
| EP11008913.3 | 2011-11-09 | ||
| PCT/EP2012/072141 WO2013068462A1 (en) | 2011-11-09 | 2012-11-08 | Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an n-containing group as vanilloid receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103906736A true CN103906736A (zh) | 2014-07-02 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280055195.9A Pending CN103906736A (zh) | 2011-11-09 | 2012-11-08 | 作为类香草素受体配体的具有被含n-基团取代的苯基基团的被取代的基于吡唑基的羧酰胺和脲衍生物 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107108593A (zh) * | 2014-11-24 | 2017-08-29 | 美迪福伦Dbt有限公司 | 作为类香草素受体配体ii的基于取代的恶唑和噻唑的羧酰胺和脲衍生物 |
| CN114920697A (zh) * | 2022-05-16 | 2022-08-19 | 河南应用技术职业学院 | 杂环基取代的茚满丙酰胺类化合物及其应用 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007045462A2 (de) * | 2005-10-19 | 2007-04-26 | Grünenthal GmbH | Neue vanilloid-rezeptor liganden und ihre verwendung zur herstellung von arzneimitteln |
| CN101679370A (zh) * | 2007-04-16 | 2010-03-24 | 格吕伦塔尔有限公司 | 香草素受体配体及其在制备药物中的用途 |
| CN101687799A (zh) * | 2007-04-16 | 2010-03-31 | 格吕伦塔尔有限公司 | 新的香草素受体配体及其在制备药物中的用途 |
| WO2010127856A1 (en) * | 2009-05-07 | 2010-11-11 | Grünenthal GmbH | Substituted phenyllureas and phenylamides as vanilloid receptor ligands |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8998598A (en) * | 1997-09-11 | 1999-03-29 | Nissan Chemical Industries Ltd. | Pyrazole compounds and plant disease control agent |
| US7998995B2 (en) * | 2006-12-08 | 2011-08-16 | Exelixis Patent Company Llc | LXR and FXR modulators |
| PL2427436T3 (pl) | 2009-05-07 | 2013-06-28 | Gruenenthal Gmbh | Podstawione aromatyczne pochodne karboksamidu i mocznika jako ligandy receptora waniloidowego |
| EP2776424A1 (en) * | 2011-11-09 | 2014-09-17 | Grünenthal GmbH | Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an n-cyclic group as vanilloid receptor ligands |
-
2012
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- 2012-11-08 TW TW101141482A patent/TW201326134A/zh unknown
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- 2012-11-08 HK HK15102577.0A patent/HK1202116A1/xx unknown
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- 2012-11-08 IN IN847KON2014 patent/IN2014KN00847A/en unknown
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- 2012-11-08 JP JP2014540454A patent/JP2014532742A/ja active Pending
- 2012-11-08 CN CN201280055195.9A patent/CN103906736A/zh active Pending
- 2012-11-08 KR KR1020147015425A patent/KR20140096351A/ko not_active Withdrawn
- 2012-11-08 MX MX2014005611A patent/MX2014005611A/es not_active Application Discontinuation
- 2012-11-08 BR BR112014010957A patent/BR112014010957A2/pt not_active IP Right Cessation
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007045462A2 (de) * | 2005-10-19 | 2007-04-26 | Grünenthal GmbH | Neue vanilloid-rezeptor liganden und ihre verwendung zur herstellung von arzneimitteln |
| CN101679370A (zh) * | 2007-04-16 | 2010-03-24 | 格吕伦塔尔有限公司 | 香草素受体配体及其在制备药物中的用途 |
| CN101687799A (zh) * | 2007-04-16 | 2010-03-31 | 格吕伦塔尔有限公司 | 新的香草素受体配体及其在制备药物中的用途 |
| WO2010127856A1 (en) * | 2009-05-07 | 2010-11-11 | Grünenthal GmbH | Substituted phenyllureas and phenylamides as vanilloid receptor ligands |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107108593A (zh) * | 2014-11-24 | 2017-08-29 | 美迪福伦Dbt有限公司 | 作为类香草素受体配体ii的基于取代的恶唑和噻唑的羧酰胺和脲衍生物 |
| CN107108593B (zh) * | 2014-11-24 | 2020-03-24 | 美迪福伦Dbt有限公司 | 作为类香草素受体配体ii的基于取代的恶唑和噻唑的羧酰胺和脲衍生物 |
| CN114920697A (zh) * | 2022-05-16 | 2022-08-19 | 河南应用技术职业学院 | 杂环基取代的茚满丙酰胺类化合物及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014532742A (ja) | 2014-12-08 |
| CA2854935A1 (en) | 2013-05-16 |
| EP2776399A1 (en) | 2014-09-17 |
| MX2014005611A (es) | 2014-07-30 |
| IN2014KN00847A (enrdf_load_html_response) | 2015-10-02 |
| KR20140096351A (ko) | 2014-08-05 |
| BR112014010957A2 (pt) | 2017-06-06 |
| AR088701A1 (es) | 2014-06-25 |
| AU2012334066A1 (en) | 2014-05-22 |
| WO2013068462A1 (en) | 2013-05-16 |
| HK1202116A1 (en) | 2015-09-18 |
| TW201326134A (zh) | 2013-07-01 |
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