CN103900997A - Sample analyser and method and device for detecting liquor drainage of sampling needle - Google Patents
Sample analyser and method and device for detecting liquor drainage of sampling needle Download PDFInfo
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- CN103900997A CN103900997A CN201210587021.9A CN201210587021A CN103900997A CN 103900997 A CN103900997 A CN 103900997A CN 201210587021 A CN201210587021 A CN 201210587021A CN 103900997 A CN103900997 A CN 103900997A
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Abstract
The invention discloses a sample analyser and a method and device for detecting liquor drainage of a sampling needle. The method comprises the following steps: firstly, controlling the sampling needle to move downwards to a first distance below the liquid level of reaction liquid in a reaction vessel when the sampling needle discharges liquid; confirming a liquid level signal, and then controlling the sampling needle to move upwards for a second distance from the first distance below the liquid level; controlling the sampling needle to discharge liquid to the reaction vessel in the process of controlling the sampling needle to move upwards for the second distance, or controlling the sampling needle to discharge liquid to the reaction vessel after controlling the sampling needle to move upwards for the second distance and stopping moving. The sampling needle is controlled to move upwards after the first liquor drainage is confirmed to be correct, and discharges liquor in the process of moving upwards or after moving upwards to a preset position and stopping moving. Thus, the sampling needle can be prevented from being excessively immersed into the reaction liquid after liquid is discharged, and the area of the polluted outer wall of the sampling needle is reduced.
Description
Technical field
The application relates to sample analyser, relates in particular to sample analyser and detects whether correct method and the device of sampling needle discharge opeing.
Background technology
Biochemical Analyzer is respectively chemical reagent (being called for short reagent below) and patient blood sample (being called for short sample below) to be joined in reaction vessels by sampling needle, and according to the difference of test event, same reaction vessels can have the application of sample process of 2 ~ 4 times; Then fully mix and carry out chemical reaction by reagent, sample; Detect the mode of transmitance with illumination again, reach testing goal, thereby determine the concentration of the each composition of sample, assist clinical diagnosis.In above-mentioned whole process, correctly adding of reagent sample is to ensure the correct key element of test result.
Correctly adding mainly of reagent sample ensured by two kinds of modes: the one, and the accuracy of the accuracy guarantee application of sample amount by syringe, the 2nd, by liquid level detection function, liquid height in reaction vessels is confirmed, thereby confirm whether liquid correctly adds, and avoids occurring false results.Whether confirm for liquid height, can adopt easy liquid height detection method, the object detecting is not the height value that obtains liquid, but can contact liq after confirmation sampling needle decline certain distance.Adopt easy liquid height to detect to judge that the method whether liquid correctly adds is called the whether correct simple and easy method of detection sampling needle discharge opeing, can have two schemes:
One is in N(N >=2) confirm the at this moment existing liquid of reaction cup before inferior application of sample.First calculate according to existing amount of liquid in reaction vessels the distance that sampling needle declines, if a front application of sample is correct, sampling needle just can submerge in liquid, for example just can enter the following X millimeter of liquid level, now there is the feedback signal of liquid level, before showing, liquid correctly adds, and now carries out this application of sample again; If a front application of sample does not correctly add, sampling needle does not have liquid level signal feedback, and instrument can provide warning, this test of cancelling, and can not cause the false results of unknown cause to be tested.The shortcoming of this kind of method is, after once correctly adding before confirming, to and then carry out this stock layout, if when this stock layout volume is more, will cause reaction vessels liquid height to raise a lot, as X millimeter under liquid level before application of sample, after application of sample, increased again the liquid height of X millimeter, the submerge degree of depth of liquid level of sampling needle is increased to 2X millimeter, has increased the contaminated area of pin outer wall, will cause serious cross pollution if sampling needle cleaning is insufficient, impact is the result of test next time; Whether the another one shortcoming of this kind of method is once correctly to add before can only judging, cannot determine whether this discharge opeing correctly completes, because once correctly added before needing only, sampling needle in discharge opeing process always under liquid, there is liquid level signal feedback always, even if this stock layout is incorrect, also cannot know.
Another kind is, in N(N >=1) inferior application of sample confirms after completing, process is as follows: if for the second time and above stock layout, first add this stock layout amount according to the existing amount of liquid of reaction vessels, the position stopping while determining sampling needle stock layout, can ensure sampling needle needle point after this stock layout certain position below liquid that submerges, if be exactly X millimeter according to the explanation of previous example, because it is after stock layout, can not cause the extra contaminated degree of depth of pin outer wall.The shortcoming of this kind of method is, can only judge that whether this application of sample is correct, for above for the second time stock layout, cannot locate concrete failure cause to some special circumstances, for example the N time application of sample do not have liquid level signal feedback, and the N-1 time application of sample is while requiring to determine whether that application of sample is correct due to the sequential of instrument own, must adopt stock layout high up in the air to carry out as the N-1 time stock layout time (this kind of situation cannot judge discharge opeing before and after whether correct), cannot locate is which time stock layout goes wrong and causes fault to occur, and carries out problem investigation increased difficulty to user.
Summary of the invention
The application provides another kind of whether correct simple and easy method and the device of sampling needle discharge opeing that detect, and reduces sampling needle contaminated area in the time detecting liquid level.
According to the application's first aspect, the application provides a kind of method that detects sampling needle discharge opeing, comprising:
Come downwards to following first distance of liquid level of reactant liquor in reaction vessels according to existing amount of liquid control sampling needle in reaction vessels, described the first distance is more than or equal to 0 and be less than the degree of depth of existing liquid in reaction vessels;
Be confirmed whether liquid level signal;
Control sampling needle by the up second distance of following the first distance of liquid level, described second distance is more than or equal to the first distance;
In the process of controlling sampling needle up second distance, control sampling needle to discharge opeing in reaction vessels or after controlling the up second distance of sampling needle and stopping, controlling again sampling needle to discharge opeing in reaction vessels.
According to the application's second aspect, the application provides a kind of device that detects sampling needle discharge opeing, comprising:
Driving control unit, for come downwards to following first distance of liquid level of reactant liquor in reaction vessels according to the existing amount of liquid control of reaction vessels sampling needle, and control sampling needle by the up second distance of following the first distance of liquid level, described the first distance is more than or equal to 0 and be less than the degree of depth of existing liquid in reaction vessels, and described second distance is more than or equal to the first distance;
Judging unit, for being confirmed whether liquid level signal;
Discharge opeing control module, for controlling sampling needle in the process of the up second distance of driver element control sampling needle to discharge opeing in reaction vessels, or controls sampling needle again to discharge opeing in reaction vessels at the up second distance of driver element control sampling needle and after stopping.
According to the application's the third aspect, the application provides a kind of sample analyser, comprising:
Reaction tray mechanism, reaction tray mechanism comprises the reaction tray for carrying reaction vessels;
For the reactant liquor loader mechanism of anti-using liquid is provided;
Travel mechanism;
Sampling needle, it is fixed in travel mechanism, and for inhale sample from reactant liquor loader mechanism under the drive of travel mechanism, and to discharge opeing in the reaction vessels of reaction tray carrying, described sampling needle is configured in the time that it contacts liquid level self electrical property and changes;
Liquid level sensor, it is coupled to sampling needle, and the electrical property that detects sampling needle changes, and output is with the level detection signal of sampling needle electrical property variation;
Processor, it is coupled to respectively travel mechanism, sampling needle and liquid level sensor, controlling travel mechanism drives sampling needle to move to reaction vessels top, come downwards to following first distance of liquid level of reactant liquor in reaction vessels according to existing amount of liquid control sampling needle in reaction vessels, receive the level detection signal of liquid level sensor output, and be confirmed whether liquid level signal, then control sampling needle by the up second distance of following the first distance of liquid level, in the process of controlling sampling needle up second distance, control sampling needle to discharge opeing in reaction vessels simultaneously or after controlling the up second distance of sampling needle and stopping, controlling again sampling needle to discharge opeing in reaction vessels, described the first distance is more than or equal to 0 and be less than the degree of depth of existing liquid in reaction vessels, and described second distance is more than or equal to the first distance.
It is up that the application controls sampling needle after carrying out level detection for a front discharge opeing, limit up limit discharge opeing or carry out discharge opeing after being up to precalculated position and stopping, can avoid like this sampling needle to have after discharge opeing is too much partially immersed in reactant liquor, reduce the contaminated area of sampling needle outer wall, and contribute to improve the detection speed of analyser entirety.
Brief description of the drawings
Fig. 1 is the structural representation in one embodiment of discharge opeing part of Biochemical Analyzer;
Fig. 2 is the process flow diagram that detects the correct discharge opeing of sampling needle in a kind of embodiment of the application;
Fig. 3 is the process flow diagram of sampling needle discharge opeing in a kind of specific embodiment of the application;
Fig. 4 a is the schematic diagram of sampling needle in discharge opeing reference position;
Fig. 4 b is the schematic diagram of sampling needle in discharge opeing process;
Fig. 4 c is the schematic diagram of sampling needle at discharge opeing end position.
Embodiment
By reference to the accompanying drawings the present invention is described in further detail below by embodiment.
The application's method and apparatus can be applicable to various sample need to being discharged in the sample analyser of testing in reaction vessels, is applied to Biochemical Analyzer below describes as example taking the application's method and apparatus.
Biochemical Analyzer mainly comprises reaction tray mechanism, reactant liquor loader mechanism, travel mechanism, sampling needle and processor.Processor communicates to connect with reaction tray mechanism, reactant liquor loader mechanism and travel mechanism respectively, controls the action of each several part.
Reaction tray mechanism comprises the reaction tray for carrying reaction vessels, reactant liquor loader mechanism is for carrying to the anti-using liquid injecting in reaction tray, for example sample and reagent, therefore reactant liquor loader mechanism can comprise sample loader mechanism and reagent loader mechanism, accordingly, travel mechanism comprises sample charging mechanism and reagent adding mechanism.Sampling needle comprises specimen needle and reagent needles, is separately fixed in sample charging mechanism and reagent adding mechanism.Sample loader mechanism is used for providing tested sample, comprises sample disk or sample conveyer frames.Sample charging mechanism is used under the control of processor, driving the sample container of specimen needle from sample disk or sample conveyer frames to draw sample, and is filled in reaction cup.Reagent loader mechanism is used for providing reaction reagent, generally includes reagent disc.Reagent adding mechanism is used under the control of processor, driving the reagent container of reagent needles from reagent disc to draw reagent, and reagent is filled in reaction cup.
In the course of the work, for confirming the whether correct discharge opeing of sampling needle, need to detect the liquid level in reaction cup, therefore, Biochemical Analyzer also comprises liquid level sensor, sampling needle be configured to when its contact when liquid level self electrical property change, for example sampling needle is configured to the one or more characteristics in selfcapacity, inductance and resistance in the time that it contacts liquid level and changes.For example, sampling needle is made into bilayer, outer pin wall ring set is outside internal layer pin wall, internal layer pin wall and outer pin wall form an equivalent capacity, outer pin wall is shorter than internal layer pin wall, and in the time of internal layer pin wall contact liquid level, the electric capacity between internal layer pin wall and outer pin wall is undergone mutation.Liquid level sensor is coupled to sampling needle, detects the capacitance variations of sampling needle, and output with the level detection signal of sampling needle capacitance variations to processor.For liquid level checking method, it will be understood by those skilled in the art that except utilizing capacitance variations to detect liquid level, can also adopt other method to carry out level detection, for example utilize resistance or inductance to change to detect liquid level.Accordingly, also should adopt the sampling needle suitable with liquid level checking method.The electrical property that liquid level sensor detects sampling needle changes, and the level detection signal that output changes with sampling needle electrical property is to processor.
Level detection signal can be the analog electrical signal that an amplitude changes with sampling needle electrical property, is transferred to the processor of analyser after analog to digital conversion.Processor has determined whether liquid level signal according to level detection signal, for example, when recognize liquid level signal (sudden change in level detection signal) from level detection signal time, think that sampling needle touches liquid level, in the time that None-identified is to liquid level signal from level detection signal, think that sampling needle does not touch liquid level.Level detection signal can be also a level signal, for example, for example, in the time that certain electrical property value of sampling needle (electric capacity) is within setting range, liquid level sensor output low level, when this electrical property value of sampling needle exceedes after setting range, liquid level sensor output high level, this level signal outputs to processor.Whether processor is liquid level signal according to electrical level judging.
In the embodiment of the present application, in the time that sampling needle need to carry out discharge opeing next time, processor control travel mechanism drives sampling needle to move to reaction vessels top, then comes downwards to following first distance of liquid level of reactant liquor in reaction vessels, to carry out level detection.When sampling needle is for the first time in reaction vessels when discharge opeing, now, because there is no reactant liquor in reaction vessels, do not need to carry out level detection, sampling needle does not need to come downwards to following first distance of liquid level of reactant liquor in reaction vessels.In the time having had a discharge opeing (no matter being injecting sample or reagent) in reaction vessels at least, processor control sampling needle comes downwards to following first distance of liquid level of reactant liquor in reaction vessels, and carries out level detection.Processor receives the level detection signal of liquid level sensor output, and be confirmed whether liquid level signal, then processor control sampling needle is by the up second distance of following the first distance of liquid level, in the process of controlling sampling needle up second distance, control sampling needle to discharge opeing in reaction vessels or after controlling the up second distance of sampling needle and stopping, controlling again sampling needle to discharge opeing in reaction vessels, in the time controlling the discharge opeing of up limit, sampling needle limit, if after arrival stop position, still do not have drained, can after sampling needle stops, controlling sampling needle continue discharge opeing until drained.The first distance and second distance can set in advance or calculate by computing formula according to lifting rate.
The scheme of the embodiment of the present application both can detect before sampling needle once whether correct discharge opeing, can reduce again the length that sampling needle submerges in reactant liquor, avoided sampling needle outer wall contaminated.For the scheme of sampling needle limit up limit discharge opeing, due to up and two operations of discharge opeing are carried out simultaneously, also can save total running time, improve the detection speed of analyser entirety.
In another embodiment, second distance is less than or equal to the first distance and the degree of depth sum of this sampling needle to discharge opeing in reaction vessels, processor is being controlled after sampling needle discharge opeing also based on being confirmed whether liquid level signal from the level detection signal of liquid level sensor reception, thereby whether this discharge opeing correctly judges to sampling needle, if do not recognize liquid level signal, think that this discharge opeing is incorrect, output alarm signal, makes analyser display reminding window or carry out sound and light alarm on human-computer interaction interface.
In specific embodiment, sampling needle can be specimen needle and/or reagent needles, and sampling needle is realized suction action by syringe control.As shown in Figure 1, syringe 1 is connected with application of sample pipeline 3 by three-way connection 2, and application of sample pipeline 3 is connected with sampling needle 7, and syringe 1 is realized suction action by moving up and down; Sampling needle 7 is fixed on rigidity rocker arm assembly 5, carries out horizontal and vertical motion by driven unit 4, realizes the suction action of diverse location; After sampling needle 7 contacts with liquid, can level detection signal feedback be judged to processor or host computer by liquid level sensor 6, control next step action, if wrong, provide warning; Sampling needle 7 is discharged to liquid in reaction vessels 8 after inhaling sample, supports it to detect, and obtains concentration results.
Based on above-mentioned Biochemical Analyzer, detect the method for the correct discharge opeing of sampling needle as shown in Figure 2, comprise the following steps:
After discharge opeing finishes, in a kind of instantiation, second distance is less than or equal to the first distance and the degree of depth sum of this sampling needle to discharge opeing in reaction vessels, to ensure still having part to submerge below liquid level at drained liquid post-sampling pin, so that judge that by level detection whether this discharge opeing is correct.In another instantiation, the liquid level after second distance can also complete higher than each discharge opeing, in such cases, each discharge opeing completes more than post-sampling pin is positioned at liquid level, and sampling needle does not contact with reactant liquor.
For for the second time and above discharge opeing, below taking sampling needle as reagent needles, reagent needles carries out the 2nd application of sample discharge opeing process to reaction vessels and sets forth as example.Reagent needles discharge opeing process is as shown in Figure 3:
Fig. 4 b represents that sampling needle 7 upwards moves with certain speed in stock layout process simultaneously, moves towards discharge opeing end position 19, i.e. this discharge opeing finishes the last position stopping of post-sampling pin 7.
Fig. 4 c represents that sampling needle 7 discharge opeings finish, and under the liquid level while having ensured that by the process of Fig. 4 b sampling needle 7 stops, the degree of depth 14 meets the demands; 20 indications are the amount of liquid after discharge opeing for the second time.Discharge opeing end position 19 is calculated as follows: calculate liquid height 17 after discharge opeing for the second time by discharge opeing volume for the second time and discharge opeing volume sum for the first time, according to the degree of depth under liquid level 14, cup upright position, the end 9, initial upright position 10 obtains stop position distance 18, thereby determine discharge opeing end position 19, in the time that sampling needle 7 is positioned at discharge opeing end position 19, also need to confirm that whether the feedback signal of liquid level sensor 6 is correct, if there is no liquid level signal, need provide warning, illustrate that discharge opeing does not accurately add for the second time, confirm that sampling needle being lifted away to liquid level to initial upright position 10 after liquid level signal continues action below again.
Can analogize for third and fourth discharge opeing process, all regard the 8 liquid storage amounts of the reaction vessels before discharge opeing as for the first time discharge opeing and finish, discharge opeing is for the second time regarded in discharge opeing below as.
In this process, emphasis will ensure the degree of depth 14 and sampling needle travelling speed under liquid level.Under liquid level, the degree of depth 14 illustrates above, need to determine according to the concrete error component of instrument, if ensure that pin is at the correct liquid level signal that just necessarily can feed back of this position stock layout; Pin travelling speed needs to adjust according to known distance, be that discharge opeing end position 19 is known with the distance of discharge opeing reference position 16, the speed that faller gill liquid causes liquid level to rise is known, by the vertical travelling speed of this two known quantities design sampling needle 7, ensureing that pin submerges the area of liquid can be not excessive.
In whole discharge opeing process, both can accurately judge whether liquid correctly enters in reaction vessels 8 like this, ensure that sampling needle 7, in the subsurface degree of depth 14, reduced its contaminated area, Optimal performance simultaneously.
The device of the detection sampling needle discharge opeing based on said method comprises driving control unit, judging unit and discharge opeing control module, driving control unit comes downwards to following first distance of liquid level of reaction vessels reactant liquor for controlling sampling needle, then control sampling needle by the up second distance of following the first distance of liquid level, described the first distance is more than or equal to 0 and be less than the degree of depth of existing liquid in reaction vessels, and described second distance is more than or equal to the first distance; Judging unit is used for being confirmed whether liquid level signal; Discharge opeing control module is for control sampling needle in the process of the up second distance of driver element control sampling needle to discharge opeing in reaction vessels simultaneously, or controls sampling needle at the up second distance of driver element control sampling needle and after stopping to discharge opeing in reaction vessels again.
In another embodiment, judging unit reaffirms whether there is liquid level signal after the discharge opeing of discharge opeing control module control sampling needle, each confirm there is no liquid level signal after output alarm signal.
Liquid level in above-described embodiment can be the liquid level that calculates according to the shapometer of lifting rate and reaction vessels and definite liquid level, can be also definite liquid level after the liquid level that adopts the liquid level of actual measurement to calculate theory is modified.
The device that detects sampling needle discharge opeing can be an integrated chip or multiple integrated chip, for example, be integrated in above-mentioned processor, realizes above-mentioned functions by computer program.
Above content is in conjunction with concrete embodiment further description made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, can also make some simple deduction or replace.
Claims (13)
1. detect a method for sampling needle discharge opeing, it is characterized in that comprising:
Control following the first distance of liquid level that sampling needle comes downwards to reactant liquor in reaction vessels, described the first distance is more than or equal to 0 and be less than the degree of depth of existing liquid in reaction vessels;
Be confirmed whether liquid level signal;
Control sampling needle by the up second distance of following the first distance of liquid level, described second distance is more than or equal to the first distance;
In the process of controlling sampling needle up second distance, control sampling needle to discharge opeing in reaction vessels or after controlling the up second distance of sampling needle and stopping, controlling again sampling needle to discharge opeing in reaction vessels.
2. the method for claim 1, is characterized in that, described second distance is less than or equal to the first distance and the degree of depth sum of this sampling needle to institute's discharging liquid in reaction vessels.
3. the method for claim 1, is characterized in that, control sampling needle come downwards to reaction vessels in below the liquid level of reactant liquor first apart from time had lifting rate once at least in reaction vessels.
4. method as claimed any one in claims 1 to 3, is characterized in that, has been confirmed whether liquid level signal controlling after sampling needle discharge opeing finishes.
5. the method as described in any one in claim 1 to 4, is characterized in that, is being confirmed whether after liquid level signal at every turn, if liquid level signal do not detected, reports to the police.
6. control a device for sampling needle discharge opeing, it is characterized in that comprising:
Driving control unit, first come downwards to following first distance of liquid level of reaction vessels reactant liquor for controlling sampling needle, and then control sampling needle by the up second distance of following the first distance of liquid level, described the first distance is more than or equal to 0 and be less than the degree of depth of existing liquid in reaction vessels, and described second distance is more than or equal to the first distance;
Judging unit, for being confirmed whether liquid level signal;
Discharge opeing control module, for controlling sampling needle in the process of the up second distance of driver element control sampling needle to discharge opeing in reaction vessels, or controls sampling needle again to discharge opeing in reaction vessels at the up second distance of driver element control sampling needle and after stopping.
7. device as claimed in claim 6, is characterized in that, described second distance is less than or equal to the first distance and the degree of depth sum of this sampling needle to institute's discharging liquid in reaction vessels.
8. the device as described in claim 6 or 7, is characterized in that, judging unit reaffirms whether there is liquid level signal after the discharge opeing of discharge opeing control module control sampling needle.
9. the device as described in any one in claim 6 to 8, is characterized in that, judging unit each confirm there is no liquid level signal after output alarm signal.
10. a sample analyser, is characterized in that comprising:
Reaction tray mechanism, reaction tray mechanism comprises the reaction tray for carrying reaction vessels;
Reactant liquor loader mechanism, for providing anti-using liquid;
Travel mechanism;
Sampling needle, it is fixed in travel mechanism, and for inhale sample from reactant liquor loader mechanism under the drive of travel mechanism, and to discharge opeing in the reaction vessels of reaction tray carrying, described sampling needle is configured in the time that it contacts liquid level self electrical property and changes;
Liquid level sensor, it is coupled to sampling needle, and the electrical property that detects sampling needle changes, and output is with the level detection signal of sampling needle self electrical property variation;
Processor, it is coupled to respectively travel mechanism, sampling needle and liquid level sensor, controlling travel mechanism drives sampling needle to move to reaction vessels top, control following the first distance of liquid level that sampling needle comes downwards to reactant liquor in reaction vessels, receive the level detection signal of liquid level sensor output, and be confirmed whether liquid level signal, then control sampling needle by the up second distance of following the first distance of liquid level, in the process of controlling sampling needle up second distance, control sampling needle to discharge opeing in reaction vessels or after controlling the up second distance of sampling needle and stopping, controlling again sampling needle to discharge opeing in reaction vessels, described the first distance is more than or equal to 0 and be less than the degree of depth of existing liquid in reaction vessels, and described second distance is more than or equal to the first distance.
11. sample analysers as claimed in claim 10, is characterized in that, described second distance is less than or equal to the first distance and the degree of depth sum of this sampling needle to discharge opeing in reaction vessels.
12. sample analysers as described in claim 10 or 11, is characterized in that, processor has been confirmed whether liquid level signal controlling after sampling needle discharge opeing the level detection signal based on receiving from liquid level sensor again.
13. sample analysers as described in any one in claim 10 to 12, is characterized in that, processor each confirm there is no liquid level signal after output alarm signal.
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017008249A1 (en) * | 2015-07-14 | 2017-01-19 | 深圳迈瑞生物医疗电子股份有限公司 | Sampling mechanism, skipped-vacuum testing method therefor, and sample analyzer |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62273429A (en) * | 1986-05-22 | 1987-11-27 | Hitachi Electronics Eng Co Ltd | Control system for transplanting needle |
| CN101135584A (en) * | 2006-08-31 | 2008-03-05 | 深圳迈瑞生物医疗电子股份有限公司 | Detecting probe liquid level detector and method |
| CN101308158A (en) * | 2007-05-15 | 2008-11-19 | 株式会社日立高新技术 | Liquid separate injection device |
| WO2011091245A1 (en) * | 2010-01-22 | 2011-07-28 | Siemens Healthcare Diagnostics Inc. | Methods, systems, and apparatus to determine a clot carryout condition upon probe retraction during sample aspiration and dispensing |
| CN202033242U (en) * | 2011-03-01 | 2011-11-09 | 北京瑞利分析仪器有限公司 | Fully-automatic liquid treatment workstation for atomic spectrum analysis |
| CN102695957A (en) * | 2010-01-13 | 2012-09-26 | 株式会社日立高新技术 | Automatic analyzing device |
-
2012
- 2012-12-28 CN CN201210587021.9A patent/CN103900997B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62273429A (en) * | 1986-05-22 | 1987-11-27 | Hitachi Electronics Eng Co Ltd | Control system for transplanting needle |
| CN101135584A (en) * | 2006-08-31 | 2008-03-05 | 深圳迈瑞生物医疗电子股份有限公司 | Detecting probe liquid level detector and method |
| CN101308158A (en) * | 2007-05-15 | 2008-11-19 | 株式会社日立高新技术 | Liquid separate injection device |
| CN102695957A (en) * | 2010-01-13 | 2012-09-26 | 株式会社日立高新技术 | Automatic analyzing device |
| WO2011091245A1 (en) * | 2010-01-22 | 2011-07-28 | Siemens Healthcare Diagnostics Inc. | Methods, systems, and apparatus to determine a clot carryout condition upon probe retraction during sample aspiration and dispensing |
| CN202033242U (en) * | 2011-03-01 | 2011-11-09 | 北京瑞利分析仪器有限公司 | Fully-automatic liquid treatment workstation for atomic spectrum analysis |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107709958A (en) * | 2015-07-14 | 2018-02-16 | 深圳迈瑞生物医疗电子股份有限公司 | Sampling mechanism and its suction detection method, sample analyser |
| WO2017008249A1 (en) * | 2015-07-14 | 2017-01-19 | 深圳迈瑞生物医疗电子股份有限公司 | Sampling mechanism, skipped-vacuum testing method therefor, and sample analyzer |
| CN107709958B (en) * | 2015-07-14 | 2020-04-14 | 深圳迈瑞生物医疗电子股份有限公司 | Sampling mechanism, air suction detection method thereof and sample analyzer |
| CN107643699B (en) * | 2017-09-30 | 2019-11-01 | 迈克医疗电子有限公司 | It takes hydraulic control method, apparatus and takes liquid system |
| CN107643699A (en) * | 2017-09-30 | 2018-01-30 | 迈克医疗电子有限公司 | Take hydraulic control method, apparatus and take liquid system |
| CN108676924A (en) * | 2018-06-01 | 2018-10-19 | 安图实验仪器(郑州)有限公司 | The segmentation loading methods of small space small size sample-adding pipe |
| CN110261595A (en) * | 2019-07-17 | 2019-09-20 | 安图实验仪器(郑州)有限公司 | Sample liquid suitable for chemical illumination immunity analysis instrument dilutes mixing method |
| WO2021088545A1 (en) * | 2019-11-04 | 2021-05-14 | 苏州长光华医生物医学工程有限公司 | Sample adding method for full-automatic chemiluminescence immunoassay analyzer |
| CN112881739A (en) * | 2019-11-29 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | Sample adding method and device, computer storage medium, sample analysis method and device |
| CN112881739B (en) * | 2019-11-29 | 2022-02-22 | 深圳市帝迈生物技术有限公司 | Sample adding method and device, computer storage medium, sample analysis method and device |
| CN111896759A (en) * | 2020-06-16 | 2020-11-06 | 武汉璟泓科技股份有限公司 | Method and device for eliminating influence of sample introduction process and storage medium |
| CN111896759B (en) * | 2020-06-16 | 2023-11-24 | 武汉璟泓科技股份有限公司 | Method, device and storage medium for eliminating influence of sample injection process |
| CN114054115A (en) * | 2020-07-31 | 2022-02-18 | 深圳市帝迈生物技术有限公司 | Sample adding method and device, computer storage medium and sample analysis device |
| CN114236633A (en) * | 2021-12-17 | 2022-03-25 | 深圳迎凯生物科技有限公司 | Detection method, maintenance method and sample analyzer |
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Inventor after: Li Zichao Inventor after: Wang Zhihong Inventor after: Zhu Xingcai Inventor before: Li Zichao Inventor before: Wang Zhihong Inventor before: Zhu Xingcai |
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Application publication date: 20140702 Assignee: Shenzhen Mindray Animal Medical Technology Co.,Ltd. Assignor: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS Co.,Ltd. Contract record no.: X2022440020009 Denomination of invention: Sample analyzer and method and device for detecting liquid discharge from sampling needle Granted publication date: 20181218 License type: Common License Record date: 20220804 |