CN103892166B - A kind of polypeptide factor and Chinese herbal medicine extract prepare the method for health food - Google Patents
A kind of polypeptide factor and Chinese herbal medicine extract prepare the method for health food Download PDFInfo
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- CN103892166B CN103892166B CN201410143088.2A CN201410143088A CN103892166B CN 103892166 B CN103892166 B CN 103892166B CN 201410143088 A CN201410143088 A CN 201410143088A CN 103892166 B CN103892166 B CN 103892166B
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- sus domestica
- polypeptide
- lien sus
- pericarpium citri
- citri reticulatae
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention discloses a kind of polypeptide factor and method that Chinese herbal medicine extract prepares health food, its feature it be made up of following component raw material: 1 3kg Lien Sus domestica polypeptide, 6 16kg Radix Glycyrrhizaes, Fructus Crataegi and Pericarpium Citri Reticulatae extract, 180 210kg oligomeric polysaccharides, remaining be water；Its step of preparation process is as follows: 1) Fructus Crataegi, Radix Glycyrrhizae, the preparation of Pericarpium Citri Reticulatae mixed extract；2) prepared by Lien Sus domestica polypeptide；3) dispensing；4) filter, sterilize, be dried and packaging.The present invention comprehensively utilizes Swine spleen transfer factor, oligomeric polysaccharide and some medicinal and edible Chinese medicine at many synergism, and appropriate design production technology, by various bioactivators functional food industrialization so that it has preferably enhancing human body body defenses function, regulation physiological rhythm, prevention disease and effect of promotion rehabilitation, and it is balanced in nutrition, good absorbing, in good taste, long shelf-life, price is relatively low, therefore having the wide market demand, development potentiality is huge.
Description
Technical field
The present invention relates to the preparation method of a kind of health food, particularly relate to a kind of polypeptide factor and Chinese herbal medicine extract system
The method of standby health food.
Background technology
The main flow of 21 century food development is health food, and China is the specific nutrient meeting different crowd needs
As the development priority of 21 century food industry, exploitation has bioactive transfer factor and oligosaccharide functional food is fitted just
Close this trend.It addition, China's natural resources of Chinese medicinal materials enriches, but herbal development aspect is existed research means and falls behind, it is necessary to pay attention to
The basic research of Chinese herbal medicine and developmental research.
Scientific experiments shows: the propagation of bacillus bifidus is had a significant impact by the concentration of Chinese medicine, although some Chinese medicine
The effect that stimulation of bifidobacteria is bred all is had under each concentration, but the strongest in its effect of a certain concentration: and some Chinese medicine is not
With under concentration, the impact on bacillus bifidus shows promotion respectively, suppresses or without impact.
Research proves that Fructus Crataegi, Pericarpium Citri Reticulatae have effect that stomach invigoratingization is long-pending, and Radix Glycyrrhizae can promote lactobacillus to varying degrees
Propagation, these Chinese herbal medicine have possessed the function of synergist, so having possessed the function of prebiotics.
The activity research of transfer factor finds, oral freeze-dried Swine spleen transfer factor can improve malignant tumor patient cellular immunization
Many index (drench rate of rotation, OT test, T cell subgroup), improve patient quality of life, reduce infection rate.It addition, oral spleen
The brain metastes factor can not only improve immunologic function, and has regulation effect.It is by making CD4 rise, and CD8 declines, and reaches
CD4/ CD8 ratio transfers the rehabilitation of normal equilibrium state, beneficially tumour patient to from being inverted/reducing.And, Lien Sus domestica transfer because of
Son application has no any untoward reaction, easy to use effectively, patient is prone to accept.
Qiao Dairong and height honor dialysis prepare Swine spleen transfer factor (PTF), pork measles specific transfer factor (
And rabbit spleen transfer factor (RTF) and rabbit spleen pork measles specific transfer factor (RSTF), and inquire into emphatically their reason PSTF)
Change the similarities and differences on characteristic and composition.Result shows that four kinds of transfer factors exist the biggest difference on ribose, polypeptide and aminoacid composition.
Form different between transfer factor RTF from RSTF, PTF and PST and RTF and PTF in the most same source, RSTF and PSTF.
Liu Jinhui etc., with healthy Lien Sus domestica as raw material, use pH value to regulate a ultrafiltration and prepare spleen transfer factor
(TransferFactor, be called for short TF), result of the test shows: pH value regulates Swine spleen transfer factor pH value prepared by a ultrafiltration and is
7.00, through ultraviolet spectral analysis, Swine spleen transfer factor has peak value at 250 1 260, and A260/ marks.=2.25;With two through base toluene
It is 33.51ml that method records Ribose concentration;Recording many skins content by double vena contracta methods is 313.82ml;High performance liquid chromatograph measures ammonia
Base acid content, free amino acid percentage contents contains with glutamic acid, aspartic acid, glycine, threonine and alanine successively
Measure the highest, and the content of half skin propylhomoserin, arginine, histidine, methionine, tyrosine and lysine is relatively fewer.
The activity of oligosaccharide and concertedness research, Zhou Jingxin and Yuan Jieli passes through experiment in vitro and in vivo test, inquires into
Several prebiotic preparations are to intestinal microbial population action effect.Found that oligofructose, stachyose, oligomeric xylose, oligomeric different wheat
Bud sugar all can promote the propagation of bacillus bifidus and lactobacillus, and can be acidified the pH of intestinal;The B of intestinal can be significantly improved
/ E value (bacillus bifidus and the ratio of enterobacteria quantity l og value in intestinal), increases the ratio of probiotics in intestinal, useful
Microecological balance in stable intestinal.And shown that these several prebiotic preparations have the knot of preferable regulation effect to intestinal microbial population
Opinion.
Consumer psychology and the consuming behavior of consumer of China reach its maturity, and increasingly focus on safety and effect of food
Property, the following development of functional food industry is modern science and traditional methods to keep in good health's theory to be combined, and furthers investigate and excavates
New resources, new raw material, new method and new technology, exploitation has the health food of independent intellectual property right.At present, there is many biologies to live
Property functional food be medicine and a developing direction of food industries.At present, transfer factor and oligosaccharide are in medicine and health care
The application of conduct industry is more, and the commodity developed are the most more.Wherein, transfer factor is more uses Swine spleen transfer factor (pig
Spleen-transfer factor, PS-TF)；Oligosaccharide use more be oligomeric isomaltose (also known as bifurcation oligose),
Oligofructose and oligomeric galactose etc..
At pharmaceutical preparations, the most domestic the have oral freeze-dried powder of spleen aminopeptide, spleen aminopeptide oral liquid, the transfer factor developed is noted
Penetrating liquid etc., its main component is from healthy animal spleen the many peptides and ucleotides complex extracted, and is mainly used to
Treatment recurrent respiratory tract infection, bronchitis, asthma, pneumonia, malignant tumor, serious symptom herpes zoster, psoriasis etc..State food
Drug Administration also again issued the national drug standards of new relevant transfer factor oral solution in 2008, its
In, polypeptide and nucleotide content have been made clear stipulaties the most.Owing to functional oligose has significantly increasing to bacillus bifidus
Grow effect, make bifid flora substantial increase in intestinal, be allowed to synthetic vitamin B1, B2, B6, K, nicotinic acid and folic acid etc. and increase,
And be absorbed by the body, enhance the absorption to calcium ion, be conducive to old children, the health of weakling.Long-time edible oligosaccharide malt
Sugar, human activin immunologic function, improve people's resistance to catching and healing power, can effectively decompose carcinogen,
Pharmaceutical composition containing oligosaccharide may be used for breast carcinoma of early stage, pulmonary carcinoma, prostate by subcutaneous, mouth or intravenous administration
The treatment of cancer, colon cancer etc..
In terms of health product, in current domestic main employing spleen polypeptide and Radix Astragali Fructus Lycii, Fructus Crataegi, Plumula Nelumbinis, Flos Lonicerae etc.
Medicine raw material makes various capsule, oral liquid, granule etc., and primary efficacy is for strengthening immunity, improving gastrointestinal function etc..It addition, have
Research shows, transfer factor and Fructus Lycii have the function of synergic adjustment immunity of organism, and it can be made to play optimum performance.Oligosaccharide
Functional sugar as low sugariness, low temperature has become the raw material of novel healthy food, and by the existing food analysis of China
Its various chemical constitutions also can be detected by technology with content, and this is for disclosing the relation of oligosaccharide structures, content and effect,
Promote the development important in inhibiting of China's third generation functional food.
Up to the present, on market, only a small amount of transfer factor, medicinal and edible Chinese medicine extracting solution and oligosaccharide are joined between two-by-two
The functional food of 5, many active functions food of three's compatibility simultaneously there is not yet.
Summary of the invention
It is an object of the invention to provide a kind of polypeptide factor and method that Chinese herbal medicine extract prepares health food.
The present invention is achieved like this.It is made up of following component raw material: 1-3kg Lien Sus domestica polypeptide, 6-16kg Radix Glycyrrhizae, mountain
Short, bristly hair or beard and Pericarpium Citri Reticulatae extract, 180-210kg oligomeric polysaccharide, remaining be water.
Its step of preparation process is as follows:
One, Fructus Crataegi, Radix Glycyrrhizae, the preparation of Pericarpium Citri Reticulatae mixed extract: Fructus Crataegi, Radix Glycyrrhizae, Pericarpium Citri Reticulatae are pulverized, is subsequently adding decocting
Boiling, filter and remove residue obtains filtrate, uses ultrafiltration apparatus that filtrate carries out ultrafiltration concentration and obtains extracts of Chinese herbal medicine, checks Chinese herbal medicine
Extracting solution also calculates the content of Chinese herbal medicine extract；
Two, prepared by Lien Sus domestica polypeptide: chooses fresh Lien Sus domestica and roughly grinds, then fine grinding obtains slurry, and continuous stirring makes it equal
Matter, to the slurry freezing after homogenizing 72 hours under conditions of-15 DEG C, defrosting filtering residue obtains filtrate afterwards, surpasses with doughnut
Obtaining Lien Sus domestica polypeptide extracting solution in chimney filter ultrafiltration gained filtrate, be concentrated to give Lien Sus domestica polypeptide concentrated solution, inspection Lien Sus domestica polypeptide concentrates
The content of Lien Sus domestica polypeptide in liquid；
Three, dispensing: weigh 1-3kg Lien Sus domestica polypeptide, 6-16kg Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae extract, 180-210kg oligomeric many
Sugar, wherein Lien Sus domestica polypeptide converts by the content in Lien Sus domestica polypeptide concentrated solution, and actual weigh is Lien Sus domestica polypeptide concentrated solution, sweet
Grass, Fructus Crataegi, Pericarpium Citri Reticulatae extract convert by the content in extracting solution, and actual weigh is Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae extracting solution；
Make each component uniformly mix, remove unnecessary water regulation gross weight to 270kg, be then heated to 95-100 DEG C of insulation sterilization
30min, transfers in storage tank temporary after being cooled to 60-70 DEG C；
Four, filter, sterilize, be dried and packaging: the dispensing that inspection prepares, such as qualified 100 screen filtrations of then using, then use half
Automatic liquid filling machine filling and sealing, is heated to 95-100 DEG C of insulation 30min sterilization, afterwards then with hot water injection, the most temporarily
Depositing and dry, finally packaging sampling inspection, it is qualified to check, and puts in storage.
The technique effect of the present invention: comprehensive utilization Swine spleen transfer factor, oligomeric polysaccharide and some medicinal and edible Chinese medicine are many
The synergism of aspect, and appropriate design production technology, by various bioactivators functional food industrialization so that it has
Preferably strengthen human body body defenses function, regulation physiological rhythm, prevention disease and promote effect of rehabilitation.Of the present invention
The most bioactive health food has raising immunity of organisms, regulating intestinal canal function, the effect that facilitating digestion absorbs, and merit
Can be collaborative, effect is obvious, balanced in nutrition, and good absorbing is in good taste, long shelf-life, and price is relatively low, and therefore having wide market needs
Asking, development potentiality is huge.
Detailed description of the invention
Below in conjunction with embodiment, the present invention doing specific descriptions further, its operational instances is only further to the present invention
Illustrate, should not be regarded as limitation of the present invention.
Embodiment 1
The present invention is made up of following component raw material: 1kg Lien Sus domestica polypeptide, 6kg Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae extract, 210kg are low
Poly-polysaccharide, remaining be water.
Its step of preparation process is as follows:
One, prepared by Chinese herbal medicine extract: Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae are pulverized, is subsequently adding soak by water secondary, each 1 little
Time, it is filtrated to get filtrate, uses ultrafiltration apparatus that filtrate carries out ultrafiltration concentration and obtain Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae aqueous extract, inspection
Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae aqueous extract, and calculate active substance the most in addition to water i.e. Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae water extract
Content；
Two, prepared by Lien Sus domestica polypeptide: chooses fresh Lien Sus domestica, roughly grind, then fine grinding obtains slurry, and continuous stirring makes it equal
Matter, to the slurry freezing after homogenizing 72 hours under conditions of-15 DEG C, defrosting filtering residue obtains filtrate afterwards, surpasses with doughnut
Chimney filter ultrafiltration obtains Lien Sus domestica polypeptide extracting solution, is concentrated to give Lien Sus domestica polypeptide concentrated solution, and in inspection Lien Sus domestica polypeptide concentrated solution, Lien Sus domestica is many
The content of peptide；
Three, dispensing: weigh Lien Sus domestica polypeptide concentrated solution, by 6kg Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae water extraction by the metering of 1kg Lien Sus domestica polypeptide
Thing weighing balance extracting liquorice, Fructus Crataegi, Pericarpium Citri Reticulatae aqueous extract, weigh 210kg oligomeric polysaccharide, makes each component uniformly mix, and it is unnecessary to remove
Water regulation gross weight to 270kg, be then heated to 95 DEG C insulation sterilization 30min, transfer in storage tank after being cooled to 60 DEG C
Temporary；
Four, filter, sterilize, be dried and packaging: the dispensing that inspection prepares, then filter with 100 eye mesh screens as qualified, then use
Semi-automatic liquid filling machine filling and sealing, is heated to 100 DEG C of insulation 30min sterilizations afterwards, then with hot water injection, keeps in afterwards
Drying, finally packaging sampling inspection, it is qualified to check, and puts in storage.
Embodiment 2
The present invention is made up of following component raw material: 3kg Lien Sus domestica polypeptide, 16kg Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae extract, 180kg are low
Poly-polysaccharide, remaining be water.
Its step of preparation process is as follows:
One, prepared by Chinese herbal medicine extract: Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae are pulverized, is subsequently adding soak by water secondary, each 1 little
Time, it is filtrated to get filtrate, uses ultrafiltration apparatus that filtrate carries out ultrafiltration concentration and obtain Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae aqueous extract, inspection
Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae aqueous extract, and calculate active substance the most in addition to water i.e. Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae water extract
Content；
Two, prepared by Lien Sus domestica polypeptide: chooses fresh Lien Sus domestica, roughly grind, then fine grinding obtains slurry, and continuous stirring makes it equal
Matter, to the slurry freezing after homogenizing 72 hours under conditions of-15 DEG C, defrosting filtering residue obtains filtrate afterwards, surpasses with doughnut
Chimney filter ultrafiltration obtains Lien Sus domestica polypeptide extracting solution, is concentrated to give Lien Sus domestica polypeptide concentrated solution, and in inspection Lien Sus domestica polypeptide concentrated solution, Lien Sus domestica is many
The content of peptide；
Three, dispensing: weigh Lien Sus domestica polypeptide concentrated solution by the metering of 3kg Lien Sus domestica polypeptide, carry by 16kg Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae water
Taking thing weighing balance extracting liquorice, Fructus Crataegi, Pericarpium Citri Reticulatae aqueous extract, weigh 180kg oligomeric polysaccharide, make each component uniformly mix, removal is many
Remaining water regulation gross weight, to 270kg, is then heated to 95 DEG C of insulation sterilization 30min, transfers to storage tank after being cooled to 60 DEG C
In temporary；
Four, filter, sterilize, be dried and packaging: the dispensing that inspection prepares, such as qualified 100 screen filtrations of then using, then use half
Automatic liquid filling machine filling and sealing, is heated to 100 DEG C of insulation 30min sterilizations afterwards, then with hot water injection, keeps in afterwards and dry in the air
Dry, finally packaging sampling inspection, it is qualified to check, and puts in storage.
In order to verify the effect of the present invention, there is following drug effect confirmatory experiment.
The research that bifidus bacillus, lactobacter growth are affected by use Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae extract work, result such as table 1,
Shown in table 2, table 3.
Bifidus bacillus respectively organized by table 1, the average colony count of lactic acid bacteria compares
The 20h of bifidus bacillus, lactic acid bacteria respectively organized by table 2, and the E value of 24h compares
The 20h of bifidus bacillus, lactic acid bacteria respectively organized by table 3, and the pH value of 24h compares
The experimental result explanation low concentration Radix Glycyrrhizae of table 1 table 2 table 3, Fructus Crataegi, Pericarpium Citri Reticulatae extract extract can promote double qi bar
Bacterium, lactic acid bacteria grow in vitro, and high concentration Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae extract extract then suppress bifidus bacillus, lactic acid bacteria at body
Outer growth.
The effect of research transfer factor treatment infantile respiratory tract infection repeatedly, is shown in Table 4 and table 5.
After the treatment of 43 groups of table, respiratory tract infection number of times compares
| Group | n | Treat latter 6 months upper respiratory tract infection number of times | Treat latter 6 months lower respiratory infection number of times |
| Treatment group | 50 | 1.08±1.02 | 0.20±0.42 |
| Matched group | 50 | 2.52±2.35 | 1.00±1.05 |
| Normal group | 3.16±1.65 | 1.06±0.52 | |
| T or i | -3.9747 | 2.23 | |
| p | <0.05 | <0.05 |
52 groups of cellular immune functions of table compare
| Group | CD3 +/% | CD4 +/% | CD8 +/% | CD4 +/ CD8 + |
| Treatment group | 61.08±3.76 | 43.79±4.38 | 29.91±3.86 | 1.68±0.92 |
| Matched group | 58.80±4.08 | 38.58±1.78 | 35.18±2.01 | 1.19±0.19 |
| t | 1.63 | 7.89 | -8.56 | 3.91 |
| p | >0.05 | <0.05 | <0.05 | <0.05 |
Table 4 table 5 result shows, Swine spleen transfer factor can significantly improve the body's immunity of child, repeatedly exhales children's
Inhale the therapeutic effect infected in road notable.
Embodiment 1 products obtained therefrom is as shown in table 6 to the regulation Effect study result of intestinal microbial population.
Table 6 regulating intestinal canal flora group mouse intestinal flora testing result (logCFU/g, n=40)
From table 6, after per os gives mice tested material, 4 kinds of bacterial numbers in mouse intestinal change.Low dose
Amount group compares before gavaging after gavaging, and the quantity of enterococcus and enterobacteria significantly reduces, and difference has pole significance (P < 0.
05) ;Middle dosage group gavage before compare after gavaging, the quantity of bacillus bifidus and lactobacillus substantially increases, difference have significance (
P < 0. 01) ;High dose group compares before gavaging after gavaging, and the quantity of bacillus bifidus and lactobacillus substantially increases, and difference has
Pole significance (P < 0. 01).Result shows that this product compatibility composition synergism is obvious, to pernicious bacteria (enterococcus, intestinal bar
Bacterium) inhibitory action is obvious, and profitable strain is had good cultivation effect, thus intestinal microbial population is had good two-ways regulation and makees
With.
Embodiment 1 products obtained therefrom enhancing immunity result of study is as shown in table 7-8.
The impact on mouse macrophage of table 7 trial target
The impact on NK cells in mice activity of table 8 trial target
From table 7 table 8, comparing with matched group, mouse macrophage phagocytosis is referred to by middle dosage and the high dose of trial target
Number and NK cells in mice activity are significantly improved, and difference has significance, show that trial target compatibility composition synergism is obvious, have
The effect of enhancing human body immunity function.
Claims (1)
1. the method that polypeptide factor and Chinese herbal medicine extract prepare health food, its feature it by following component raw material system
Become: 1-3kg Lien Sus domestica polypeptide, 6-16kg Radix Glycyrrhizae, Fructus Crataegi and Pericarpium Citri Reticulatae extract, 180-210kg oligomeric polysaccharide, remaining be water；Its system
Standby processing step is as follows:
1) Fructus Crataegi, Radix Glycyrrhizae, the preparation of Pericarpium Citri Reticulatae mixed extract: Fructus Crataegi, Radix Glycyrrhizae, Pericarpium Citri Reticulatae are pulverized, is subsequently adding soak by water, filter
Remove slag and obtain filtrate, use ultrafiltration apparatus that filtrate carries out ultrafiltration concentration and obtain extracts of Chinese herbal medicine, check extracts of Chinese herbal medicine
And calculate the content of Chinese herbal medicine extract；
2) prepared by Lien Sus domestica polypeptide: chooses fresh Lien Sus domestica and roughly grinds, then fine grinding obtains slurry, and continuous stirring makes it uniform ,-
To the slurry freezing after stirring 72 hours under conditions of 15 DEG C, thaw afterwards, filtering residue, obtain filtrate, surpass with doughnut
Obtaining Lien Sus domestica polypeptide extracting solution in chimney filter ultrafiltration gained filtrate, be concentrated to give Lien Sus domestica polypeptide concentrated solution, inspection Lien Sus domestica polypeptide concentrates
The content of Lien Sus domestica polypeptide in liquid；
3) dispensing: weigh 1-3kg Lien Sus domestica polypeptide, 6-16kg Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae extract, 180-210kg oligomeric polysaccharide, its
Middle Lien Sus domestica polypeptide converts by the content in Lien Sus domestica polypeptide concentrated solution, and actual weigh is Lien Sus domestica polypeptide concentrated solution, Radix Glycyrrhizae, mountain
Short, bristly hair or beard, Pericarpium Citri Reticulatae extract convert by the content in extracting solution, and actual weigh is Radix Glycyrrhizae, Fructus Crataegi, Pericarpium Citri Reticulatae extracting solution；Make each group
Point uniformly mixing, removes unnecessary water regulation gross weight to 270kg, is then heated to 95-100 DEG C of insulation sterilization 30min, cooling
Transfer in storage tank temporary after 60-70 DEG C；
4) filter, sterilize, be dried and packaging: the dispensing that inspection prepares, such as qualified 100 screen filtrations of then using, then with semi-automatic
Liquid-filling machine filling and sealing, is heated to 95-100 DEG C of insulation 30min sterilization afterwards, then with hot water injection, keeps in afterwards and dry in the air
Dry, finally packaging sampling inspection, it is qualified to check, and puts in storage.
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| CN109793167A (en) * | 2017-11-17 | 2019-05-24 | 江西康宝医药生物科技有限公司 | A kind of oral solution of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity |
| CN109674064A (en) * | 2019-02-20 | 2019-04-26 | 江西德泰医药生物技术有限公司 | A kind of compound colostrinin and preparation method thereof |
| CN114504613A (en) * | 2020-11-17 | 2022-05-17 | 湖南星贸食品有限公司 | Formula and preparation method of honeysuckle prebiotics beverage |
| CN115644455B (en) * | 2022-12-08 | 2023-04-04 | 北京第一生物科技开发有限公司 | Application of bovine spleen peptide powder in improving intestinal function |
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| CN101057864A (en) * | 2006-04-17 | 2007-10-24 | 肇庆学院 | Technology for preparing anti influenza virus transfer factors |
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