CN109793167A - A kind of oral solution of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity - Google Patents
A kind of oral solution of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity Download PDFInfo
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- CN109793167A CN109793167A CN201711143383.8A CN201711143383A CN109793167A CN 109793167 A CN109793167 A CN 109793167A CN 201711143383 A CN201711143383 A CN 201711143383A CN 109793167 A CN109793167 A CN 109793167A
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- pig spleen
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Abstract
The present invention provides a kind of oral solution of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity, and primary raw material includes: pig spleen extract, docosahexaenoic acid micro mist, taurine, zinc gluconate, sucrose, sorbic acid, pure water；Process flow are as follows: dissolve pig spleen extract, γ-aminobutyric acid, alpha-linolenic acid, docosahexaenoic acid (DHA) micro mist, taurine, zinc gluconate, sucrose, sorbic acid, water etc. in material-compound tank; it stirs and evenly mixs; constant volume; filtering; filling, sterilizing, is packed at lamp inspection to obtain the final product；The present invention in pig spleen preparation process using the fresh pig the spleen channel through quarantining except impurity, repeatedly degreasing, smash to pieces, be homogenized, multigelation, pancreatin hydrolysis, heat inactivation enzyme, clarification, filtration sterilization, ultrafiltration collect, detection etc. main techniques be made, safety, efficiently, environmentally friendly；Pig spleen extract has effects that immunological regulation, and oral solution is made also to have both the above effect.
Description
Technical field
The present invention relates to chemical industry field of biotechnology, are related to the enzymatic hydrolysis and extractive technique of pig spleen extract, specifically a kind of
Auxiliary adjustment immunity, improves oral solution of function of constitution and preparation method thereof.
Background technique
Nowadays, it with the development of society, the work and study life stress of people becomes larger, lives without rule, stays up late, crapulence
Gluttony reduces immunity constantly, brings a lot of discomfort, and pig spleen extract has effects that adjust immunity, and pig spleen price
Cheap, abundance is widely used in manufacturing drug series of products, and traditional extracting method mostly uses thawing technology, consumes
Duration, virus are killed and are not thorough, the inadequate safety and environmental protection of production process.
Summary of the invention
The purpose of the present invention is to provide a kind of auxiliary adjustment immunity, improve the oral solution and preparation method of constitution, with
Solve the problems, such as that above-mentioned technical background technology proposes.
To achieve the above object, the invention provides the following technical scheme:
A kind of oral solution of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity, primary raw material include: pig spleen extract,
Docosahexaenoic acid micro mist, taurine, zinc gluconate, sucrose, sorbic acid, pure water；By pig spleen extract, 22 carbon six
Olefin(e) acid (DHA) micro mist, taurine, zinc gluconate, sucrose, sorbic acid, water etc. dissolve in material-compound tank, stir and evenly mix, constant volume,
Filtering, filling, sterilizing, is packed at lamp inspection to obtain the final product.
Preferably, in a kind of oral solution of above-mentioned pig spleen extract fusion Chinese medicine auxiliary adjustment immunity, feature exists
In the pig spleen extract preparation process flow are as follows: the fresh pig spleen for quarantine of learning from else's experience removes the impurity such as fascia；It is taken off repeatedly
Rouge adds 4 times of amount purified waters to be smashed to pieces 2 high speeds of its point with high speed bruisher (20,000 revs/min of revolving speed) after cleaning using purified water
Cell；After 20 mesh filter-cloth filterings, it is homogenized with homogenizer (pressure 200Kg or more)；Multigelation is added citric acid and adjusts PH
Value, obtains low molecular weight small peptide, free amino acid, mixture of ribonucleotides with pancreatin hydrolysis, which is heated to 40-50 DEG C
It except enzyme living, then will dispense except enzyme solution to container, and do clarifying treatment；Carry out aseptic filtration；Take clear liquid using ultrafiltration instrument (with 20,000
The retention of molecular weight ultrafiltration membrane) ultrafiltration collects, pig spleen extracting solution is obtained after detection processing.
Preferably, in a kind of oral solution of above-mentioned pig spleen extract fusion Chinese medicine auxiliary adjustment immunity, described one kind
The oral liquid prescription of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity are as follows: pig spleen extract 114ml, γ-aminobutyric acid
It is 60ml, alpha-linolenic acid 60ml, docosahexaenoic acid (DHA) micro mist 84.8g, taurine 250g, zinc gluconate 37.1g, white
Granulated sugar 1000g, sorbic acid 3g, water 10000ml；It dissolves, stirs and evenly mixs in material-compound tank, constant volume, filtering, filling 1000 oral
Liquid.
It can be seen via above technical scheme that compared with prior art, the present invention strengthens in the preparation process of pig spleen
Using nanoscale cell crushing technology is shortened the production cycle to the biosafety control of raw material sources and production process, is reduced
Energy consumption keeps macromolecular substances degradation in product more thorough using pancreatin hydrolysis, and enriches the bioactivity member of product,
Using " one-step method " elimination virus, removal fat, cell fragment remains the impurity such as albuminate and nucleic acid, saves than traditional handicraft
When, it is efficient, safe and environment-friendly the advantages that.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
The embodiment of invention for those of ordinary skill in the art without creative efforts, can also basis
The attached drawing of offer obtains other attached drawings.
Fig. 1 attached drawing is that pig spleen of the invention extracts flow chart.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Example 1
A kind of oral solution of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity of the present invention is by following weight proportion
Raw material brewed form: pig spleen extract 114ml, γ-aminobutyric acid 60ml, alpha-linolenic acid 60ml, docosahexaenoic acid
(DHA) micro mist 84.8g, taurine 250g, zinc gluconate 37.1g, white granulated sugar 1000g, sorbic acid 3g, water 10000ml；Matching
It dissolves, stirs and evenly mixs in batch can, constant volume, filtering, filling 1000 oral solutions.
Table 1
The requirement of pig spleen extract quality
Table 2
Docosahexaenoic acid (DHA) micro mist quality requirement
Pig spleen extract and docosahexaenoic acid (DHA) micro mist are detected according to table 1, table 2, more safety can
It leans on.
Each embodiment in this specification is described in a progressive manner, the highlights of each of the examples are with other
The difference of embodiment, the same or similar parts in each embodiment may refer to each other.For device disclosed in embodiment
For, since it is corresponded to the methods disclosed in the examples, so being described relatively simple, related place is said referring to method part
It is bright.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention.
Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein
General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention
It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one
The widest scope of cause.
Claims (3)
1. a kind of oral solution of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity, primary raw material include: pig spleen extract,
γ-aminobutyric acid, alpha-linolenic acid, docosahexaenoic acid micro mist, taurine, zinc gluconate, sucrose, sorbic acid, pure water；It will
Pig spleen extract, docosahexaenoic acid (DHA) micro mist, taurine, zinc gluconate, sucrose, sorbic acid, water etc. are in material-compound tank
Middle dissolution, stirs and evenly mixs, constant volume, and filtering, filling, sterilizing, is packed at lamp inspection to obtain the final product.
2. a kind of oral solution of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity according to claim 1, feature
It is, the pig spleen extract preparation process flow are as follows: the fresh pig spleen for quarantine of learning from else's experience removes the impurity such as fascia；It is taken off repeatedly
Rouge adds 4 times of amount purified waters to be smashed to pieces 2 high speeds of its point with high speed bruisher (20,000 revs/min of revolving speed) after cleaning using purified water
Cell；After 20 mesh filter-cloth filterings, it is homogenized with homogenizer (pressure 200Kg or more)；Multigelation is added citric acid and adjusts PH
Value, obtains low molecular weight small peptide, free amino acid, mixture of ribonucleotides with pancreatin hydrolysis, which is heated to 40-50 DEG C and removes
Enzyme living, then will dispense except enzyme solution to container, do clarifying treatment；Carry out aseptic filtration；Clear liquid is taken to use ultrafiltration instrument (very much with 2
The retention of son amount ultrafiltration membrane) ultrafiltration collects, pig spleen extracting solution is obtained after detection processing.
3. a kind of oral solution of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity according to claim 1, feature
It is, a kind of oral liquid prescription of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity are as follows: pig spleen extract 114ml,
γ-aminobutyric acid 60ml, alpha-linolenic acid 60ml, docosahexaenoic acid (DHA) micro mist 84.8g, taurine 250g, gluconic acid
Zinc 37.1g, white granulated sugar 1000g, sorbic acid 3g, water 10000ml；It dissolves, stirs and evenly mixs in material-compound tank, constant volume filters, filling
1000 oral solutions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711143383.8A CN109793167A (en) | 2017-11-17 | 2017-11-17 | A kind of oral solution of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711143383.8A CN109793167A (en) | 2017-11-17 | 2017-11-17 | A kind of oral solution of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109793167A true CN109793167A (en) | 2019-05-24 |
Family
ID=66554786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711143383.8A Pending CN109793167A (en) | 2017-11-17 | 2017-11-17 | A kind of oral solution of pig spleen extract fusion Chinese medicine auxiliary adjustment immunity |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1097141A (en) * | 1994-01-07 | 1995-01-11 | 张成武 | A kind of life-prolonging immunopotentiator |
| CN1634987A (en) * | 2004-03-10 | 2005-07-06 | 菲尔斯·杜克制药（通化）有限公司 | Spleen polypeptide extract, its preparing process and use |
| CN103194513A (en) * | 2013-03-27 | 2013-07-10 | 浙江丰安生物制药有限公司 | Method for efficiently extracting spleen aminopeptide |
| CN103892166A (en) * | 2014-04-11 | 2014-07-02 | 江西德泰医药生物技术有限公司 | Method for preparing health food by polypeptide factor and Chinese herb extracts |
| CN103989041A (en) * | 2014-04-11 | 2014-08-20 | 南昌大学 | Multi-biological activity function food and preparation process thereof |
-
2017
- 2017-11-17 CN CN201711143383.8A patent/CN109793167A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1097141A (en) * | 1994-01-07 | 1995-01-11 | 张成武 | A kind of life-prolonging immunopotentiator |
| CN1634987A (en) * | 2004-03-10 | 2005-07-06 | 菲尔斯·杜克制药（通化）有限公司 | Spleen polypeptide extract, its preparing process and use |
| CN103194513A (en) * | 2013-03-27 | 2013-07-10 | 浙江丰安生物制药有限公司 | Method for efficiently extracting spleen aminopeptide |
| CN103892166A (en) * | 2014-04-11 | 2014-07-02 | 江西德泰医药生物技术有限公司 | Method for preparing health food by polypeptide factor and Chinese herb extracts |
| CN103989041A (en) * | 2014-04-11 | 2014-08-20 | 南昌大学 | Multi-biological activity function food and preparation process thereof |
Non-Patent Citations (1)
| Title |
|---|
| 袁霖: "猪脾多肽的制备工艺研究", 《肉类工业》 * |
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Application publication date: 20190524 |