CN109806279A - A kind of Medulla sus domestica extract fusion Chinese medicine improves the oral solution of memory - Google Patents

A kind of Medulla sus domestica extract fusion Chinese medicine improves the oral solution of memory Download PDF

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Publication number
CN109806279A
CN109806279A CN201711143384.2A CN201711143384A CN109806279A CN 109806279 A CN109806279 A CN 109806279A CN 201711143384 A CN201711143384 A CN 201711143384A CN 109806279 A CN109806279 A CN 109806279A
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CN
China
Prior art keywords
sus domestica
acid
medulla sus
domestica extract
chinese medicine
Prior art date
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Pending
Application number
CN201711143384.2A
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Chinese (zh)
Inventor
聂亚臻
邹国辉
熊亮
聂建群
邹欢
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JIANGXI KANGBAO MEDICAL BIOLOGICAL TECHNOLOGY Co Ltd
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JIANGXI KANGBAO MEDICAL BIOLOGICAL TECHNOLOGY Co Ltd
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Priority to CN201711143384.2A priority Critical patent/CN109806279A/en
Publication of CN109806279A publication Critical patent/CN109806279A/en
Pending legal-status Critical Current

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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention provides a kind of oral solution of Medulla sus domestica extract fusion Chinese medicine improvement memory, and primary raw material includes: Medulla sus domestica extract, docosahexaenoic acid (DHA) micro mist, γ-aminobutyric acid, alpha-linolenic acid;Taurine, zinc gluconate, sucrose, sorbic acid, pure water;Process flow are as follows: Medulla sus domestica extract, docosahexaenoic acid (DHA) micro mist, taurine, zinc gluconate, sucrose, sorbic acid, water etc. are dissolved in material-compound tank, stirred and evenly mixed, constant volume, is filtered, filling, sterilizing, is packed at lamp inspection to obtain the final product;The main techniques such as the present invention cleaned, smashed to pieces using the fresh pig brain through quarantining in pig brain preparation process, homogeneous, freeze thawing, ultrafiltration, concentration are made, and sediment deep processing can extract cholesterol or fish bait is made, safety, efficiently, environmental protection;The effect of Medulla sus domestica extract has brain boosting and supplementing, improves memory, makes oral solution also have both the above effect.

Description

A kind of Medulla sus domestica extract fusion Chinese medicine improves the oral solution of memory
Technical field
The present invention relates to chemical industry field of biotechnology, are related to the enzymatic hydrolysis and extractive technique of Medulla sus domestica extract, specifically a kind of Auxiliary improvement of memory improves oral solution of function of anoxia endurance and preparation method thereof.
Background technique
Nowadays, with the development of society, mental worker is more and more, overtime work also becomes normality, various overstrain one's nerves to make Worker's decrease of memory, it is uncomfortable;Medulla sus domestica extract is rich in brain polypeptide, is a kind of biology system with brain boosting and supplementing Agent, and pig brain is cheap, abundance, is widely used in manufacturing brain polypeptide series products, traditional extracting method mostly uses Thawing technology, time-consuming, and virus is killed and is not thorough, the inadequate safety and environmental protection of production process.
Summary of the invention
The purpose of the present invention is to provide a kind of nutrition brain, improve memory, improve anoxia endurance oral solution and Preparation method, to solve the problems, such as that above-mentioned technical background technology proposes.
To achieve the above object, the invention provides the following technical scheme:
A kind of Medulla sus domestica extract fusion Chinese medicine improves the oral solution of memory, and primary raw material includes: Medulla sus domestica extract, 22 Carbon acid micro mist, taurine, zinc gluconate, sucrose, sorbic acid, pure water;By Medulla sus domestica extract, docosahexaenoic acid (DHA) micro mist, γ-aminobutyric acid, alpha-linolenic acid taurine, zinc gluconate, sucrose, sorbic acid, water etc. it is molten in material-compound tank Solution, stirs and evenly mixs, constant volume, filters, filling, sterilizing, is packed at lamp inspection to obtain the final product.
Preferably, improve the oral solution of memory in a kind of above-mentioned Medulla sus domestica extract fusion Chinese medicine, which is characterized in that described Medulla sus domestica extract preparation process flow are as follows: the fresh pig brain for quarantine of learning from else's experience removes fascia, fat, brain centrum impurity;Use purifying After water is cleaned, add 4 times of amount purified water high speed bruishers (20,000 revs/min of revolving speed) by the damaged cell of 2 high speeds of its point;With 20 mesh It after filter-cloth filtering, is detected, with homogenizer (pressure 200Kg or more) homogenate;Citric acid is added and adjusts pH value, with complex enzyme water Solution obtains low molecular weight small peptide, free amino acid, mixture of ribonucleotides;The enzymolysis liquid is heated to 40-50 DEG C except enzyme living, then will remove Enzyme solution is dispensed to container;It puts as -200 DEG C of freezers, freezing is taken out after 12-24 hours, sets room temperature thawing;Supernatant is taken to use Centrifuge high speed centrifugation, can will be fatty, the big molecular impurities such as cell fragment, remaining albuminate and nucleic acid carry out deep processing obtain Cholesterol or be processed into fish bait, extracting centrifugal liquid ultrafiltration instrument (with the retention of 20,000 molecular weight ultrafiltration membranes) ultrafiltration, to being mentioned after ultrafiltration It takes liquid to test, adjusts;It can get pig brain extracting solution.
Preferably, improve the oral solution of memory in a kind of above-mentioned Medulla sus domestica extract fusion Chinese medicine, a kind of pig brain mentions Take object fusion Chinese medicine improve memory oral liquid prescription are as follows: Medulla sus domestica extract 114ml, docosahexaenoic acid (DHA) micro mist 84.8g, γ-aminobutyric acid 50ml, alpha-linolenic acid 50ml, taurine 250g, zinc gluconate 37.1g, white granulated sugar 1000g, mountain Pears acid 3g, water 10000ml;It dissolves, stirs and evenly mixs in material-compound tank, constant volume, filtering, filling 1000 oral solutions.
It can be seen via above technical scheme that compared with prior art, the present invention strengthens in the preparation process of pig brain Using nanoscale cell crushing technology is shortened the production cycle to the biosafety control of raw material sources and production process, is reduced Energy consumption using the complex enzyme of protease and nuclease, by protein and nuclease synchronous hydrolysis, makes macromolecular substances in product It degrades more thorough, and enriches the bioactivity member of product, using " one-step method " elimination virus, removal is fatty, cell fragment, The impurity such as albuminate and nucleic acid are remained, sediment deep processing can extract cholesterol or fish bait is made, saves than traditional handicraft When, it is efficient, safe and environment-friendly the advantages that.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this The embodiment of invention for those of ordinary skill in the art without creative efforts, can also basis The attached drawing of offer obtains other attached drawings.
Fig. 1 attached drawing is that pig brain of the invention extracts flow chart.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Example 1
A kind of Medulla sus domestica extract fusion Chinese medicine of the present invention improves the oral solution of memory by the raw material of following weight proportion It is brewed to form: Medulla sus domestica extract 114ml, docosahexaenoic acid (DHA) micro mist 84.8g, γ-aminobutyric acid 50ml, α-flax Sour 50ml, taurine 250g, zinc gluconate 37.1g, white granulated sugar 1000g, sorbic acid 3g, water 10000ml;It is molten in material-compound tank Solution, stirs and evenly mixs, constant volume, filters, filling 1000 oral solutions.
Table 1
Medulla sus domestica extract quality requirement
Table 2
Docosahexaenoic acid (DHA) micro mist quality requirement
Medulla sus domestica extract and docosahexaenoic acid (DHA) micro mist are detected according to table 1, table 2, more safety can It leans on.
Each embodiment in this specification is described in a progressive manner, the highlights of each of the examples are with other The difference of embodiment, the same or similar parts in each embodiment may refer to each other.For device disclosed in embodiment For, since it is corresponded to the methods disclosed in the examples, so being described relatively simple, related place is said referring to method part It is bright.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one The widest scope of cause.

Claims (3)

1. a kind of Medulla sus domestica extract fusion Chinese medicine improves the oral solution of memory, primary raw material includes: Medulla sus domestica extract, 22 carbon Acid micro mist, taurine, zinc gluconate, sucrose, sorbic acid, pure water;By Medulla sus domestica extract, docosahexaenoic acid (DHA) micro mist, γ-aminobutyric acid, alpha-linolenic acid, taurine, zinc gluconate, sucrose, sorbic acid, water etc. are molten in material-compound tank Solution, stirs and evenly mixs, constant volume, filters, filling, sterilizing, is packed at lamp inspection to obtain the final product.
2. the oral solution that a kind of Medulla sus domestica extract fusion Chinese medicine according to claim 1 improves memory, which is characterized in that institute State Medulla sus domestica extract preparation process flow are as follows: the fresh pig brain for quarantine of learning from else's experience removes fascia, fat, brain centrum impurity;Using pure After change water is cleaned, add 4 times of amount purified water high speed bruishers (20,000 revs/min of revolving speed) by the damaged cells of 2 high speeds of its point;With 20 It after mesh filter-cloth filtering, is detected, with homogenizer (pressure 200Kg or more) homogenate;Citric acid is added and adjusts pH value, uses complex enzyme Hydrolysis obtains low molecular weight small peptide, free amino acid, mixture of ribonucleotides;The enzymolysis liquid is heated to 40-50 DEG C except enzyme living, then will Except enzyme solution is dispensed to container;It puts as -200 DEG C of freezers, freezing is taken out after 12-24 hours, sets room temperature thawing;Supernatant is taken to make With centrifuge high speed centrifugation, can will be fatty, the big molecular impurities such as cell fragment, remaining albuminate and nucleic acid carry out deep processing It obtains cholesterol or is processed into fish bait, extracting centrifugal liquid (retains) ultrafiltration with ultrafiltration instrument with 20,000 molecular weight ultrafiltration membranes, after ultrafiltration Extracting solution is tested, adjustment;It can get pig brain extracting solution.
3. the oral solution that a kind of Medulla sus domestica extract fusion Chinese medicine according to claim 1 improves memory, which is characterized in that institute Stating a kind of Medulla sus domestica extract fusion Chinese medicine improves the oral liquid prescription of memory are as follows: Medulla sus domestica extract 114ml, two dodecahexaenes Sour (DHA) micro mist 84.8g, γ-aminobutyric acid 50ml, alpha-linolenic acid 50ml, taurine 250g, zinc gluconate 37.1g, white sand Sugared 1000g, sorbic acid 3g, water 10000ml;It dissolves, stirs and evenly mixs in material-compound tank, constant volume, filtering, filling 1000 oral Liquid.
CN201711143384.2A 2017-11-17 2017-11-17 A kind of Medulla sus domestica extract fusion Chinese medicine improves the oral solution of memory Pending CN109806279A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102863508A (en) * 2011-07-05 2013-01-09 江西康宝医药生物科技有限公司 Extraction technology of cerebral polypeptides
CN105998072A (en) * 2016-07-08 2016-10-12 杭州华缔集团生物科技有限公司 Pig brain extract, composition containing pig brain extract and application of composition
CN106692166A (en) * 2015-11-18 2017-05-24 珠海宝德润生健康科技有限公司 Composition with memory improving function, and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102863508A (en) * 2011-07-05 2013-01-09 江西康宝医药生物科技有限公司 Extraction technology of cerebral polypeptides
CN106692166A (en) * 2015-11-18 2017-05-24 珠海宝德润生健康科技有限公司 Composition with memory improving function, and preparation method thereof
CN105998072A (en) * 2016-07-08 2016-10-12 杭州华缔集团生物科技有限公司 Pig brain extract, composition containing pig brain extract and application of composition

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