CN103889457A - 使用特异性的基于壳聚糖的纳米复合物用于有效并安全递送siRNA的组合物和方法 - Google Patents

使用特异性的基于壳聚糖的纳米复合物用于有效并安全递送siRNA的组合物和方法 Download PDF

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CN103889457A
CN103889457A CN201280036662.3A CN201280036662A CN103889457A CN 103889457 A CN103889457 A CN 103889457A CN 201280036662 A CN201280036662 A CN 201280036662A CN 103889457 A CN103889457 A CN 103889457A
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cancer
chitosan
composition
nucleic acid
acid sequence
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阿卜杜拉扎克·马尔祖基
迈克尔·D·布施曼
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Polyvalor SC
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CN201280036662.3A 2011-05-24 2012-05-24 使用特异性的基于壳聚糖的纳米复合物用于有效并安全递送siRNA的组合物和方法 Pending CN103889457A (zh)

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Application Number Priority Date Filing Date Title
US201161489302P 2011-05-24 2011-05-24
US201161489306P 2011-05-24 2011-05-24
US61/489,302 2011-05-24
US61/489,306 2011-05-24
PCT/CA2012/050342 WO2012159215A1 (en) 2011-05-24 2012-05-24 Compositions and methods for efficacious and safe delivery of sirna using specific chitosan-based nanocomplexes

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CN103889457A true CN103889457A (zh) 2014-06-25

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US (3) US20150087689A1 (https=)
EP (1) EP2714089A4 (https=)
JP (1) JP2014518875A (https=)
KR (1) KR20140051182A (https=)
CN (1) CN103889457A (https=)
AU (1) AU2012260399A1 (https=)
CA (1) CA2835147A1 (https=)
HK (1) HK1199215A1 (https=)
WO (1) WO2012159215A1 (https=)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108117585A (zh) * 2018-01-16 2018-06-05 合肥诺为尔基因科技服务有限公司 一种靶向导入siRNA促进乳腺癌细胞凋亡的多肽
CN110396524A (zh) * 2019-05-31 2019-11-01 海南大学 一种用于蚊虫的RNAi纳米颗粒和制备方法及用途
CN112423734A (zh) * 2018-06-27 2021-02-26 奈科斯特拉研究有限公司 具有改善的肠吸收的纳米粒形式的用于口服施用多硫酸戊聚糖的组合物
CN115252807A (zh) * 2016-07-27 2022-11-01 利兰斯坦福初级大学董事会 用于核酸递送的解体型细胞穿透性复合物
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