CN103860993A - Grains for removing heat from lung to relieve cough and preparation method thereof - Google Patents
Grains for removing heat from lung to relieve cough and preparation method thereof Download PDFInfo
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- CN103860993A CN103860993A CN201410101845.XA CN201410101845A CN103860993A CN 103860993 A CN103860993 A CN 103860993A CN 201410101845 A CN201410101845 A CN 201410101845A CN 103860993 A CN103860993 A CN 103860993A
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Abstract
The invention belongs to the technical field of traditional Chinese medicines and particularly relates to grains for removing heat from lung to relieve cough and a preparation method thereof. The grains comprise the following components in parts by weight: 2 parts of folium mori, 1 part of chrysanthemum, 3 parts of rhizoma phragmitis, 1 part of Scutellaria baicalensis, 3 parts of white mulberry root-bark, 3 parts of cordate houttuynia, 1 part of subprostrate sophora, 2 parts of folium eriobotryae, 1 part of tangerine, 1 part of Pinellia ternata (prepared), 1 part of Platycodon grandiflorum, 1 part of semen armeniacae amarae (fried), 1 part of common hogfennel root, 1 part of aster (processed with honey), 2 parts of radix stemonae (processed with honey) and 1 part of liquorice. The medicinal materials according to the formula are selected based on the physiological property of the lung and a mild medication way of focusing on expelling the evil factors is used without adopting bitter, cold, heavy and turbid medicinal materials; precious and limited traditional Chinese medicinal materials are replaced by common traditional Chinese medical materials, and therefore the grains disclosed by the invention are low in cost, safe in medication and complete and reasonable in composition and lay equal stress on clearing away heat and preventing phlegm from forming and stopping coughing.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of clearing away lung-heat to relieve cough granule and preparation method.
Background technology
" lung is the five internal organs canopy ", " lung being a delicate viscus, cold-resistant heat ", these physiological propertys of lung have just determined that exopathogen very easily violates lung, cause impairment of dispersing and descending function of the lung, and there is the symptoms such as cough, excessive phlegm, and violate in lung at various exopathogen, common with wind heat, for cough due to pathogenic wind-heat's treatment, should be according to the physiological property of lung, follow Wu clearly and bring up the old maxim that logical " Wenbing Tiaobian, Detailed Analysis of Epidemic Warm Diseases " " controls the part of the body cavity above the diaphragm housing the heart and lungs as plumage, non-light erectile problem ", it is main that Selection drug should gently be advocated clearly, must guard against bitter cold deep.And existing clearing heat, eliminating phlegm, relieving cough class Chinese patent medicine niuhuang shedan chuanbei mixture, fritillary and loquat cough mixture, intensified loquet distillate prescription Calculus Bovis used, Fel Serpentis are the deep product of bitter cold; Bulbus Fritillariae Cirrhosae natural resources scarcity, expensive; Pericarpium Papaveris belongs to national restricted Chinese crude drug, the easy addiction of long-term taking.From prescription, niuhuang shedan chuanbei mixture clearing away heat-fire power is large, antitussive action deficiency, and then both are taking cough-relieving as main, and eliminating heat from the lung strength is inferior.Use separately the clinical problem that is difficult to solve wind heat and phlegm-heat cough, then both need adapted Western medicine anti-inflammation class medicine in use.
Summary of the invention
The eutherapeutic clearing away lung-heat to relieve cough granule of one and the preparation method that the object of the invention is to overcome above-mentioned technical problem and provide.
A kind of clearing away lung-heat to relieve cough granule, comprises following component by weight:
Folium Mori 2 weight portions, Flos Chrysanthemi 1 weight portion, Rhizoma Phragmitis 3 weight portions, Radix Scutellariae 1 weight portion, Cortex Mori 3 weight portions, Herba Houttuyniae 3 weight portions, Radix Sophorae Tonkinensis 1 weight portion, Folium Eriobotryae 2 weight portions, Exocarpium Citri Rubrum 1 weight portion, Rhizoma Pinelliae (processed) 1 weight portion, Radix Platycodonis 1 weight portion, Semen Armeniacae Amarum (stir-fry) 1 weight portion, Radix Peucedani 1 weight portion, Radix Asteris (processed with honey) 1 weight portion, the Radix Stemonae (processed with honey) 2 weight portions, Radix Glycyrrhizae 1 weight portion.
A preparation method for clearing away lung-heat to relieve cough granule, comprises the steps:
(1) get Herba Houttuyniae, Cortex Mori, Folium Eriobotryae extraction volatile oil, put into container and save backup;
(2) Herba Houttuyniae, Cortex Mori, Folium Eriobotryae extract after volatile oil medicinal residues and other 13 herbal medicine decoct twice altogether, and 1 hour for the first time, 0.5 hour for the second time, collecting decoction, filtered;
(3) filtrate is concentrated into 1ml and is equivalent to crude drug 2g, adds 1 times of amount ethanol, stirs evenly, and leaves standstill 24 hours, filters, and uses decompression tank to reclaim after ethanol, leaves standstill, and filters, and filtrate is concentrated into relative density 1.30 ~ 1.35(60 DEG C) thick paste;
(4) get 1 part of thick paste, 3 parts of sucrose, 1 part, dextrin is mixed into spice, and the volatile oil in the dilution proportion step 1 of ethanol 2:1 is sprayed in above-mentioned spice, adopts 80% alcoholic solution to stir spice and makes soft material;
(5) above-mentioned soft material is crossed No. one to sieve, 60 DEG C of oven dry, granule processed, after the sterilizing of epoxy hexane, places 7-10 days, can obtain described clearing away lung-heat to relieve cough granule.
Selection drug embodies the physiological property of lungs, and light clear advocation of medication, abandons bitter cold deep, substitutes famous and precious and restricted Chinese crude drug with parts of generic medicinal plants, cheap, drug safety, and prescription comprehensive and reasonable, heat clearing away and preventing phlegm from forming and stopping coughing are laid equal stress on.
In side, Folium Mori bitter but sweet flavor is cold in nature, and Flos Chrysanthemi sweet-bitter flavor is cool in nature, all enters lung meridian, gently disperses clearly, and eliminating heat from the lung, is principal agent altogether; Herba Houttuyniae, Radix Sophorae Tonkinensis heat-clearing and toxic substances removing, Rhizoma Phragmitis, Cortex Mori, Radix Scutellariae clearing heat and purging lung, to help the power of Folium Mori, the clear part of the body cavity above the diaphragm housing the heart and lungs lung-heat of Flos Chrysanthemi; Folium Eriobotryae, the Rhizoma Pinelliae, Exocarpium Citri Rubrum, Radix Peucedani, Semen Armeniacae Amarum, Radix Asteris, Flos Farfarae, Radix Platycodonis, the cough-relieving of Radix Stemonae dispersing lung-QI and dissipating phlegm are accessory drugs altogether; Radix Glycyrrhizae is eliminated the phlegm, coordinating the actions of various ingredients in a prescription is adjuvant; All medicines share the merit of playing altogether removing heat from the lung and dissipating phlegm cough-relieving, the clinical disease for wind heat, phlegm-heat cough.
Folium Mori all have stronger antibacterial action to staphylococcus aureus, beta hemolytic streptococcus, diphtheria corynebacterium and anthrax bacillus.Flos Chrysanthemi is external has some inhibitory action to gram-positive bacterium (staphylococcus aureus and β Hemolytic streptococcus), Bacillus tuberculosis, and high concentration also has antiviral (PB8 strain) and anti-spirillum effect in vitro.
Herba Houttuyniae has significantly antibacterial, antivirus action, staphylococcus aureus and penicillin resistant strain thereof, Hemolytic streptococcus, Diplococcus pneumoniae, micrococcus catarrhalis, hemophilus influenza are all had to inhibitory action, can suppress serous secretion, promote tissue regeneration, there is antiinflammatory action, can obviously promote the phagocytic function of leukocyte and macrophage, the antitussive effect of significantly relievining asthma in addition.
Dauricine, to various respiratory road antibacterial, as staphylococcus aureus, Candida albicans, tubercule bacillus etc. all have inhibitory action, also has obvious antiinflammatory action.
Radix Scutellariae has wider antimicrobial spectrum, staphylococcus aureus, Hemolytic streptococcus, Diplococcus pneumoniae, diphtheria corynebacterium are being had to inhibitory action, even the staphylococcus aureus that the antimicrobial drugs such as penicillin have been developed immunity to drugs, still responsive to Radix Scutellariae, Radix Scutellariae also has antiinflammatory anti-allergic effects in addition.
Folium Eriobotryae, the contained amygdaloside of Semen Armeniacae Amarum, can be decomposed and produce hydrocyanic acid by enteric microorganism enzyme in vivo, and hydrocyanic acid has inhibitory action to respiratory center, reaches the effect of antitussive and antiasthmatic.
Exocarpium Citri Rubrum, the Rhizoma Pinelliae, Radix Platycodonis, Radix Peucedani, Radix Asteris, Flos Farfarae, the Radix Stemonae, Radix Glycyrrhizae all have expelling phlegm for arresting cough effect in various degree through modern pharmacological research.
detailed description of the invention
Below, in conjunction with example, substantive distinguishing features of the present invention and advantage are further described, but the present invention is not limited to listed embodiment.
Embodiment
A kind of clearing away lung-heat to relieve cough granule, comprises following component by weight:
Folium Mori 2 weight portions, Flos Chrysanthemi 1 weight portion, Rhizoma Phragmitis 3 weight portions, Radix Scutellariae 1 weight portion, Cortex Mori 3 weight portions, Herba Houttuyniae 3 weight portions, Radix Sophorae Tonkinensis 1 weight portion, Folium Eriobotryae 2 weight portions, Exocarpium Citri Rubrum 1 weight portion, Rhizoma Pinelliae (processed) 1 weight portion, Radix Platycodonis 1 weight portion, Semen Armeniacae Amarum (stir-fry) 1 weight portion, Radix Peucedani 1 weight portion, Radix Asteris (processed with honey) 1 weight portion, the Radix Stemonae (processed with honey) 2 weight portions, Radix Glycyrrhizae 1 weight portion.
A preparation method for clearing away lung-heat to relieve cough granule, comprises the steps:
(1) get Herba Houttuyniae, Cortex Mori, Folium Eriobotryae extraction volatile oil, put into container and save backup;
(2) Herba Houttuyniae, Cortex Mori, Folium Eriobotryae extract after volatile oil medicinal residues and other 13 herbal medicine decoct twice altogether, and 1 hour for the first time, 0.5 hour for the second time, collecting decoction, filtered;
(3) filtrate is concentrated into 1ml and is equivalent to crude drug 2g, adds 1 times of amount ethanol, stirs evenly, and leaves standstill 24 hours, filters, and uses decompression tank to reclaim after ethanol, leaves standstill, and filters, and filtrate is concentrated into relative density 1.30 ~ 1.35(60 DEG C) thick paste;
(4) get 1 part of thick paste, 3 parts of sucrose, 1 part, dextrin is mixed into spice, and the volatile oil in the dilution proportion step 1 of ethanol 2:1 is sprayed in above-mentioned spice, adopts 80% alcoholic solution to stir spice and makes soft material;
(5) above-mentioned soft material is crossed No. one to sieve, 60 DEG C of oven dry, granule processed, after the sterilizing of epoxy hexane, places 7-10 days, can obtain described particle for relieving heat and cough, is distributed into after the assay was approved bag, 15 weight portions/bag.
Usage and dosage: warm water is taken after mixing it with water, according to symptom emergency, each 1 ~ 2 bag, 7 days is a course for the treatment of.
The present invention is directed to the physiological property of the lungs such as " lung is the five internal organs canopy ", " lung being a delicate viscus; not cold-resistant heat "; follow Wu clearly and bring up the old maxim that logical " Wenbing Tiaobian, Detailed Analysis of Epidemic Warm Diseases " " controls the part of the body cavity above the diaphragm housing the heart and lungs as plumage; non-light erectile problem "; Selection drug is gently to advocate as main clearly; abandon the deep product of bitter cold; the Chinese crude drug such as deep and expensive Calculus Bovis, Fel Serpentis with the alternative bitter cold such as Folium Mori, Flos Chrysanthemi; substitute famous and precious, the restricted Chinese crude drugs such as Bulbus Fritillariae Cirrhosae, Pericarpium Papaveris with Fructus Citri tangerinae Folium Eriobotryae, the Rhizoma Pinelliae, Semen Armeniacae Amarum; and prescription is reasonable more comprehensively, embody Traditional Chinese Medicine tcm theory.In the clinical use of my institute for many years, practical proof curative effect is more better than existing similar Chinese patent medicine, and can be used alone in the present invention.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (2)
1. a clearing away lung-heat to relieve cough granule, is characterized in that, comprises following component by weight:
Folium Mori 2 weight portions, Flos Chrysanthemi 1 weight portion, Rhizoma Phragmitis 3 weight portions, Radix Scutellariae 1 weight portion, Cortex Mori 3 weight portions, Herba Houttuyniae 3 weight portions, Radix Sophorae Tonkinensis 1 weight portion, Folium Eriobotryae 2 weight portions, Exocarpium Citri Rubrum 1 weight portion, Rhizoma Pinelliae (processed) 1 weight portion, Radix Platycodonis 1 weight portion, Semen Armeniacae Amarum (stir-fry) 1 weight portion, Radix Peucedani 1 weight portion, Radix Asteris (processed with honey) 1 weight portion, the Radix Stemonae (processed with honey) 2 weight portions, Radix Glycyrrhizae 1 weight portion.
2. a preparation method for clearing away lung-heat to relieve cough granule described in claim 1, is characterized in that, comprises the steps:
(1) get Herba Houttuyniae, Cortex Mori, Folium Eriobotryae extraction volatile oil, put into container and save backup;
(2) Herba Houttuyniae, Cortex Mori, Folium Eriobotryae extract after volatile oil medicinal residues and other 13 herbal medicine decoct twice altogether, and 1 hour for the first time, 0.5 hour for the second time, collecting decoction, filtered;
(3) filtrate is concentrated into 1ml and is equivalent to crude drug 2g, adds 1 times of amount ethanol, stirs evenly, and leaves standstill 24 hours, filters, and uses decompression tank to reclaim after ethanol, leaves standstill, and filters, and filtrate is concentrated into relative density 1.30 ~ 1.35(60 DEG C) thick paste;
(4) get 1 part of thick paste, 3 parts of sucrose, 1 part, dextrin is mixed into spice, and the volatile oil in the dilution proportion step 1 of ethanol 2:1 is sprayed in above-mentioned spice, adopts 80% alcoholic solution to stir spice and makes soft material;
(5) above-mentioned soft material is crossed No. one to sieve, 60 DEG C of oven dry, granule processed, after the sterilizing of epoxy hexane, places 7-10 days, can obtain described clearing away lung-heat to relieve cough granule.
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| CN201410101845.XA CN103860993B (en) | 2014-03-19 | 2014-03-19 | A kind of clearing away lung-heat to relieve cough granule and preparation method |
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| CN201410101845.XA CN103860993B (en) | 2014-03-19 | 2014-03-19 | A kind of clearing away lung-heat to relieve cough granule and preparation method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112603975A (en) * | 2021-01-13 | 2021-04-06 | 湘潭市中心医院 | Traditional Chinese medicine granule for clearing lung heat and relieving cough, preparation method and application |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102743737A (en) * | 2012-07-26 | 2012-10-24 | 吴伶 | Chinese medicinal preparation for effectively treating tracheitis |
| CN102847026A (en) * | 2011-06-27 | 2013-01-02 | 张红旗 | A Chinese medicinal formulation for treating infiltrative pulmonary tuberculosis |
| CN103463536A (en) * | 2013-08-26 | 2013-12-25 | 荣成市科学技术情报研究所 | Traditional Chinese medicine composition for treating wind-heat affecting lung |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102847026A (en) * | 2011-06-27 | 2013-01-02 | 张红旗 | A Chinese medicinal formulation for treating infiltrative pulmonary tuberculosis |
| CN102743737A (en) * | 2012-07-26 | 2012-10-24 | 吴伶 | Chinese medicinal preparation for effectively treating tracheitis |
| CN103463536A (en) * | 2013-08-26 | 2013-12-25 | 荣成市科学技术情报研究所 | Traditional Chinese medicine composition for treating wind-heat affecting lung |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112603975A (en) * | 2021-01-13 | 2021-04-06 | 湘潭市中心医院 | Traditional Chinese medicine granule for clearing lung heat and relieving cough, preparation method and application |
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