CN103800676B - One treats neurasthenic Chinese medicine extract, preparation method and applications - Google Patents
One treats neurasthenic Chinese medicine extract, preparation method and applications Download PDFInfo
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- CN103800676B CN103800676B CN201410088718.0A CN201410088718A CN103800676B CN 103800676 B CN103800676 B CN 103800676B CN 201410088718 A CN201410088718 A CN 201410088718A CN 103800676 B CN103800676 B CN 103800676B
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Abstract
nullThe invention discloses a kind of Chinese medicine extract with treatment neurasthenia's effect，Described Chinese medicine extract is from Radix Angelicae Sinensis (Angelica sinensis)、Radix Rehmanniae Preparata (Radix Rehmanniae Preparata)、Cortex Phellodendri (Phellodendron chinense Schneid.var.glabriusculum Schneid)、Rhizoma Coptidis (Coptis chinensis Franch)、Radix Scutellariae (Scutellaria Linn.)、Rhizoma Polygonati (Rhizoma Polygonati)、The Radix Astragali (Radix Astragali)、Fructus Schisandrae Chinensis (Schisandra chinensls (Turcz) Baill.)、Fructus Lycii (Lycium barbarum L)、Radix Saposhnikoviae (DivaricateSaposhnikoviaRoot)、The Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae)、Radix Glycyrrhizae (Radix Glycyrrhizae) prepares，The invention also discloses the preparation method of this Chinese medicine extract，The invention also discloses this drug extract as the application treating neurasthenic pharmaceutical preparation.
Description
Technical field
The invention belongs to modern Chinese traditional medicine field, the present invention relates to a kind of from Radix Angelicae Sinensis (Angelica sinensis),
Radix Rehmanniae Preparata (Radix Rehmanniae Preparata), Cortex Phellodendri (Phellodendron chinense Schneid.var.
Glabriusculum Schneid), Rhizoma Coptidis (Coptis chinensis Franch), Radix Scutellariae (Scutellaria Linn.),
Rhizoma Polygonati (Rhizoma Polygonati), the Radix Astragali (Radix Astragali), Fructus Schisandrae Chinensis (Schisandra
Chinensls (Turcz) Baill.), Fructus Lycii (Lycium barbarum L), Radix Saposhnikoviae
(DivaricateSaposhnikoviaRoot), the Rhizoma Atractylodis Macrocephalae (RhizomaAtractylodisMacrocephalae), sweet
The Chinese medicine extract that grass (Radix Glycyrrhizae) extracts, is specifically related to the preparation side of a kind of Chinese medicine extract
Method and the application in preparation treatment neurasthenia's medicine thereof.
Background technology
Neurasthenia refers to that brain, due to long-term nervous and stress, thus produces ergasia ability
Weaken, its principal character: 1. easy excited, irritability；The most mental the most tired, as reading study is slightly long, then
Sense feeling of fullness in the head, giddy；Absent minded hypomnesis；3. headache, position are not fixed.4. sleep disorder,
It mostly is difficulty falling asleep, early awakening, or be difficult to fall asleep again after waking up, many nightmares；5. autonomic nervous dysfunction, satisfying
Dynamic overrun, perspire, anorexia, constipation, diarrhoea, menoxenia, premature ejaculation；6. Secondary cases hypochondriacal idea.Mostly
Number cases fall ill in 16-40 year between, both sexes morbidity number no significant difference.The person of being engaged in mental work occupies the majority.
Even primary disease is such as dealt with improperly to delay reaches several years many decades.Such as new Nervous and Mental Factors or deficiency of having a rest, symptom
Reproducible or aggravation.
The most domestic medical level still falls behind, and it is little that the medicine that various places hospital can open is substantially all difference,
The more fruitful way of nothing, cures the symptoms, not the disease, often eats more serious and more serious.The most now it is badly in need of one to control
Therapeutic effect is good, few side effects, and low-cost medicine occurs.Active strong, side effect is found from traditional medicine
Low active drug becomes the new way solving this problem.
Radix Angelicae Sinensis, motherland's medical science thinks, Radix Angelicae Sinensis sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore can manage it again
Blood, invigorating middle warmer has, has benefit, for the key medicine in blood in row.Thus, it can be enriched blood, and can invigorate blood circulation again, both may be used
Stimulate the menstrual flow, again can be active.
Radix Rehmanniae Preparata is the tuber of Radix Rehmanniae, and Radix Rehmanniae is first appeared in Shennong's Herbal, has Radix Rehmanniae, Radix Rehmanniae
And Radix Rehmanniae Preparata, but Radix Rehmanniae and Radix Rehmanniae are all the kinds of the Radix Rehmanniae, but no matter be the Radix Rehmanniae or Radix Rehmanniae Preparata, all
There is effect of YIN nourishing and the production of body fluid promoting.Radix Rehmanniae Preparata is that sweet band is sweet, and tepor will not be the coldest, returns liver, kidney channel.Typically can be with ripe
Ground carrys out nourishing YIN benefit essence, as the medicine enriched blood, and can treat blood deficiency, cardiopalmus, dizziness, insomnia, menstruation
Uncomfortable, the hepatic and renal YIN deficiency, soreness of the waist and knees, night sweat seminal emission etc..Additionally, Radix Rehmanniae Preparata also has heart tonifying, diuresis, blood sugar lowering
With the effect raising cell outside periphery, enhancing body immunity etc..
Cortex Phellodendri, for rutaceae wampee or the dry bark of Cortex Phellodendri.The former practises title " Cortex Phellodendri ", the latter
Practise and claim " Cortex Phellodendri ".Can be used as medicine, nature and flavor bitter cold, there is heat clearing and damp drying, pathogenic fire purging is except steaming, effect of detoxification sore treatment.
Rhizoma Coptidis, has another name called Wang Lian, Zhi Lian etc., herbaceos perennial, belongs to Ranunculaceae Coptis.It is a kind of conventional
Chinese medicine, can with heat clearing and damp drying, eliminating fire and detoxication, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, heart-fire high
Sheng, dysphoria and insomnia, heat in blood tell nosebleed, conjunctival congestion, have a toothache, quench one's thirst, carbuncle furuncle, eczema, eczema, auditory meatus
Suppurate, mesh, aphtha, clearing stomach, soothing liver-QI, incoordination between the liver and stomach, vomiting acid regurgitation, blood pressure lowering, removing toxic substances, arrhythmia,
Antibacterial, blood sugar lowering, antitumor, protection gastric mucosa etc..
Radix Scutellariae calls Radix Scutellariae, tsuchikane tea root, and it has heat clearing and damp drying, and removing heat from blood is antiabortive, detoxicating functions.Cure mainly
Epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, fetal movement
The diseases such as uneasiness, hypertension, carbuncle furuncle.
Rhizoma Polygonati, has another name called Rhizoma Polygonati Cirrhifolii, Caput Gallus domesticus ginseng, cures mainly deficient cold and heat, pulmonary tuberculosis hemoptysis, after being ill body void lack of appetite, muscle
Bone weakness, rheumatalgia, wind favus disease.
The Radix Astragali, has another name called continuous stilbene.The medicinal history having more than 2000 year so far of the Radix Astragali, it has enhancing body to exempt from
Epidemic disease function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and wide antibacterial action.
Fructus Schisandrae Chinensis, Fructus Schisandrae Chinensis acid temperature is nontoxic." herbal classic " proposes these product the effects such as QI invigorating qi-restoratives reinforcing YIN-essence.Go through
DAIWEN offers description Fructus Schisandrae Chinensis qi-restoratives labor, strengthening bone and muscle, special tonifying the lung kidney, hold concurrently tonifying five ZANG-organs, supplementing QI for promoting the production of body fluid.To common
The suffer from a deficiency of the kidney cough with asthma of damage, frequent micturition of quenching one's thirst, spontaneous sweating due to deficiency of QI, night sweat due to yin deficiency of senile disease lung all has therapeutical effect.To improvement
Old deficiency of heart-blood, insufficiency of heart-QI, the insomnia cardiopalmus of disarmony between the heart and kidney all have good action.
The flat sweet in the mouth of Fructus Lycii, enters liver, kidney channel, has effect of replenishing YIN and blood, nourishing the liver and kidney, replenishing vital essence to improve eyesight,
Be usually used in treating that Liver and kidney is deficient, soreness of the waist and knees caused by asthenia of essence and blood, dizziness, tinnitus, the disease such as seminal emission, to liver
Kidney deficiency, essence and blood can not on help the disease curative effects such as, visual deterioration dim-sighted in the eyes caused by mesh it is further preferred that.
Radix Saposhnikoviae, for cold, fever with chills, headache, general pain.And cold anemopyretic, fever with chills,
The disease such as conjunctival congestion, pharyngalgia.
The Rhizoma Atractylodis Macrocephalae, perennial herb, the nice and cool weather of happiness, is used as medicine with rhizome, has multinomial medicinal function.Effect:
Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.Have loose bowels for insufficiency of the spleen lack of appetite, abdominal distention, phlegm retention vertigo and palpitation, edema,
Spontaneous perspiration, frequent fetal movement.
Radix Glycyrrhizae is a kind of tonification Chinese herbal medicine, and function cures mainly heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen etc..
We are found by Pharmacodynamics screening, by extracting after being mixed according to certain proportioning by above-mentioned each medicine
To extract can substantially treat the insomnia of neurastheniac and the symptom of perspiration.
Summary of the invention
It is an object of the invention to provide a kind of therapeutic effect good, few side effects, low-cost treatment nerve declines
Weak medicine, medicine of the present invention is the drug extract of plurality of Chinese.
Another object of the present invention is to provide the method preparing this drug extract.
A further object of the present invention is that proposing this Chinese medicine extract has treatment neurasthenia's effect in preparation
Application in medicine.
In order to achieve the above object, this invention takes techniques below scheme:
(1) described medical material Radix Angelicae Sinensis (Angelica sinensis) 12 parts, Radix Rehmanniae Preparata (Radix Rehmanniae are weighed
Preparata) 30 parts, Cortex Phellodendri (Phellodendron chinense Schnid.var.glabriusculum Schneid)
9 parts, Rhizoma Coptidis (Coptis chinensis Franch) 3 parts, Radix Scutellariae (Scutellaria Linn.) 9 parts, Rhizoma Polygonati
(Rhizoma Polygonati) 18 parts, the Radix Astragali (Radix Astragali) 15 parts, Fructus Schisandrae Chinensis (Schisandra
Chinensls (Turcz) Baill.) 9 parts, Fructus Lycii (Lycium barbarumL) 18 parts, Radix Saposhnikoviae
(DivaricateSaposhnikoviaRoot) 15 parts, the Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae)
15 parts, 9 parts of Radix Glycyrrhizae (Radix Glycyrrhizae)；
(2) the medical material clear water described in step (1) is soaked；
(3) medical material the soaked mixing described in step (2) is put into drug-decocting appliance marmite to decoct；
(4) extracting solution of step (3) gained is filtered；
(5) extracting solution of step (4) gained is bottled, be placed in disinfecting container and carry out disinfection
(6) solution of step (5) gained is the Chinese medicine extract of the present invention.
As to the improvement of technique scheme with supplement:
(7) immersion process can be 6-10 hour.
(8) decoction process can be carried out at twice, for the first time doubled amount soak by water 10 hours, and second time adds 5
Times amount soak by water 2 hours.
(9) sterilisation temp of disinfecting container is for being not less than 100 DEG C.
The extract prepared by technique scheme is the plant extract of medicine food pure natural, medicine subsequently
Effect experiment will demonstrate that, the Chinese medicine extract of the present invention has effect of significant neurasthenia.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention being expanded on further, these embodiments are interpreted as being merely to illustrate
The present invention rather than limit the scope of the invention, after having read the content that the present invention records, ability
The present invention can be made various changes or modifications by field technique personnel, and these equivalence changes and modification fall into this equally
Bright claims limited range.
The preparation of embodiment 1 Chinese medicine extract
(1) described medical material Radix Angelicae Sinensis (Angelica sinensis) 12 parts, Radix Rehmanniae Preparata (Radix Rehmanniae are weighed
Preparata) 30 parts, Cortex Phellodendri (Phellodendron chinense Schneid.var.glabriusculum Schneid)
9 parts, Rhizoma Coptidis (Coptis chinensis Franch) 3 parts, Radix Scutellariae (Scutellaria Linn.) 9 parts, Rhizoma Polygonati
(Rhizoma Polygonati) 18 parts, the Radix Astragali (Radix Astragali) 15 parts, Fructus Schisandrae Chinensis (Schisandra
Chinensls (Thrcz) Baill.) 9 parts, Fructus Lycii (Lycium barbarumL) 18 parts, Radix Saposhnikoviae
(DivaricateSaposhnikoviaRoot) 15 parts, the Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae)
15 parts, 9 parts of Radix Glycyrrhizae (Radix Glycyrrhizae)；
(2) clear water of the medical material described in step (1) is soaked 6 hours；
(3) medical material the soaked mixing described in step (2) is put into drug-decocting appliance marmite to decoct；Decoct
Process can be carried out at twice, for the first time doubled amount soak by water 10 hours, and second time adds 5 times amount soak by water 2
Hour；
(4) extracting solution of step (3) gained is filtered；
(5) extracting solution of step (4) gained is bottled, be placed in disinfecting container and carry out disinfection, disinfecting container
Sterilisation temp be 100 DEG C.
(6) solution of step (5) gained is the Chinese medicine extract of the present invention.
The preparation of embodiment 2 Chinese medicine extract
(1) described medical material Radix Angelicae Sinensis (Angelica sinensis) 12 parts, Radix Rehmanniae Preparata (Radix Rehmanniae are weighed
Preparata) 30 parts, Cortex Phellodendri (Phellodendron chinense Schneid.var.glabriusculum Schneid)
9 parts, Rhizoma Coptidis (Coptis chinensis Franch) 3 parts, Radix Scutellariae (Scutellaria Linn.) 9 parts, Rhizoma Polygonati
(Rhizoma Polygonati) 18 parts, the Radix Astragali (Radix Astragali) 15 parts, Fructus Schisandrae Chinensis (Schisandra
Chinensls (Turcz) Baill.) 9 parts, Fructus Lycii (Lycium barbarumL) 18 parts, Radix Saposhnikoviae
(DivaricateSaposhnikoviaRoot) 15 parts, the Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae)
15 parts, 9 parts of Radix Glycyrrhizae (Radix Gltcyrrhizae)；
(2) clear water of the medical material described in step (1) is soaked 8 hours；
(3) medical material the soaked mixing described in step (2) is put into drug-decocting appliance marmite to decoct；Decoct
Process can be carried out at twice, for the first time doubled amount soak by water 10 hours, and second time adds 5 times amount soak by water 2
Hour；
(4) extracting solution of step (3) gained is filtered；
(5) extracting solution of step (4) gained is bottled, be placed in disinfecting container and carry out disinfection, disinfecting container
Sterilisation temp for being not less than 120 DEG C.
(6) solution of step (5) gained is the Chinese medicine extract of the present invention.
The preparation of embodiment 3 Chinese medicine extract
(1) described medical material Radix Angelicae Sinensis (Angelica sinensis) 12 parts, Radix Rehmanniae Preparata (Radix Rehmanniae are weighed
Preparata) 30 parts, Cortex Phellodendri (Phellodendron chinense Schneid.var.glabriusculum Schneid)
9 parts, Rhizoma Coptidis (Coptis chinensis Franch) 3 parts, Radix Scutellariae (Scutellaria Linn.) 9 parts, Rhizoma Polygonati
(Rhizoma Polygonati) 18 parts, the Radix Astragali (Radix Astragali) 15 parts, Fructus Schisandrae Chinensis (Schisandra
Chinensls (Turcz) Baill.) 9 parts, Fructus Lycii (Lycium barbarumL) 18 parts, Radix Saposhnikoviae
(DivaricateSaposhnikoviaRoot) 15 parts, the Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae)
15 parts, 9 parts of Radix Glycyrrhizae (Radix Glycyrrhizae)；
(2) clear water of the medical material described in step (1) is soaked 10 hours；
(3) medical material the soaked mixing described in step (2) is put into drug-decocting appliance marmite to decoct；Decoct
Process can be carried out at twice, for the first time doubled amount soak by water 10 hours, and second time adds 5 times amount soak by water 2
Hour；
(4) extracting solution of step (3) gained is filtered；
(5) extracting solution of step (4) gained is bottled, be placed in disinfecting container and carry out disinfection, disinfecting container
Sterilisation temp be 150 DEG C.
(6) solution of step (5) gained is the Chinese medicine extract of the present invention.
Embodiment 4 Chinese medicine extract treats neurasthenic functional study
Suffering from the most neurasthenic patient by 300 and be randomly divided into 3 groups, every patient sleeps first 3 hours
All taking the drug extract (whole amount every time extracted) of the present invention, every patient is adjusted by every morning
Look into, sleep after inquiry drug administration and situation about perspiring record.Carry out after 1 month adding up effective percentage, result
As shown in table 1, to have a sleepless night and to perspire as treating whether effective parameter, the drug extract treatment of the present invention
The effective percentage of neurasthenic patient reaches more than 90%, and the lighter one week, severe one are substantially alleviated for one month.
Table 1 Chinese medicine extract treats neurasthenic effective percentage
| Group | 1 | 2 | 3 |
| Total case load | 100 | 100 | 100 |
| Remission number | 90 | 96 | 97 |
| Effective percentage | 90% | 96% | 97% |
Claims (7)
1. a Chinese medicine extract, it is characterised in that described Chinese medicine extract by Radix Angelicae Sinensis 12 parts, 30 parts of Radix Rehmanniae Preparata,
Cortex Phellodendri 9 parts, Rhizoma Coptidis 3 parts, Radix Scutellariae 9 parts, Rhizoma Polygonati 18 parts, the Radix Astragali 15 parts, Fructus Schisandrae Chinensis 9 parts, Fructus Lycii
18 parts, Radix Saposhnikoviae 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, 9 parts of Radix Glycyrrhizae prepare.
2. the method preparing Chinese medicine extract as claimed in claim 1, it is characterised in that described system
Preparation Method comprises the following steps:
(1) described medical material Radix Angelicae Sinensis 12 parts, 30 parts of Radix Rehmanniae Preparata, Cortex Phellodendri 9 parts, Rhizoma Coptidis 3 parts, Radix Scutellariae 9 are weighed
Part, Rhizoma Polygonati 18 parts, the Radix Astragali 15 parts, Fructus Schisandrae Chinensis 9 parts, Fructus Lycii 18 parts, Radix Saposhnikoviae 15 parts, the Rhizoma Atractylodis Macrocephalae 15
Part, 9 parts of Radix Glycyrrhizae；
(2) the medical material clear water described in step (1) is soaked；
(3) medical material the soaked mixing described in step (2) is put into drug-decocting appliance marmite to decoct；
(4) extracting solution of step (3) gained is filtered；
(5) extracting solution of step (4) gained is bottled, be placed in disinfecting container and carry out disinfection；
(6) solution of step (5) gained is described Chinese medicine extract.
Preparation method the most according to claim 2, it is characterised in that described immersion process is that 6-10 is little
Time.
Preparation method the most according to claim 2, it is characterised in that described decoction process enters at twice
OK, doubled amount soak by water 10 hours for the first time, second time adds 5 times amount soak by water 2 hours.
Preparation method the most according to claim 2, it is characterised in that the sterilization temperature of described disinfecting container
Degree is for being not less than 100 DEG C
6. a Chinese medicine extract as claimed in claim 1 or the method according to any one of claim 2-5
The application in preparation treatment neurasthenia's medicine of the Chinese medicine extract of preparation.
7. according to the application described in claim 6, it is characterised in that described neurasthenic symptom includes
Insomnia and perspiration.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410088718.0A CN103800676B (en) | 2014-03-12 | One treats neurasthenic Chinese medicine extract, preparation method and applications |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410088718.0A CN103800676B (en) | 2014-03-12 | One treats neurasthenic Chinese medicine extract, preparation method and applications |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103800676A CN103800676A (en) | 2014-05-21 |
| CN103800676B true CN103800676B (en) | 2016-11-30 |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1169301A (en) * | 1996-06-24 | 1998-01-07 | 王春儒 | Compounded |
| CN102526329A (en) * | 2012-02-21 | 2012-07-04 | 简福川 | Traditional Chinese medicine for treating night sweat symptom |
| CN102526474A (en) * | 2012-03-22 | 2012-07-04 | 王寿江 | Chinese medicine composition for treating neurasthenia |
| CN102846822A (en) * | 2012-08-19 | 2013-01-02 | 李承平 | Capsule for soothing nerves and relieving inner heat |
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1169301A (en) * | 1996-06-24 | 1998-01-07 | 王春儒 | Compounded |
| CN102526329A (en) * | 2012-02-21 | 2012-07-04 | 简福川 | Traditional Chinese medicine for treating night sweat symptom |
| CN102526474A (en) * | 2012-03-22 | 2012-07-04 | 王寿江 | Chinese medicine composition for treating neurasthenia |
| CN102846822A (en) * | 2012-08-19 | 2013-01-02 | 李承平 | Capsule for soothing nerves and relieving inner heat |
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