CN103768343A - Chinese medicine composition for treating fundi disease and preparation method of composition - Google Patents
Chinese medicine composition for treating fundi disease and preparation method of composition Download PDFInfo
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Abstract
The invention discloses a Chinese medicine composition for treating a fundi disease. The Chinese medicine composition is prepared from the following Chinese medicinal herbs in parts by weight: 40-50 parts of fel ursi, 40-50 parts of rhizoma coptidis from Sichuan of China, 40-50 parts of butterflybush flower, 40-50 parts of notopterygium root, 25-35 parts of pillis ophidiae, 25-35 parts of cortex lycii radicis, 25-35 parts of herba epimedii, 25-35 parts of equisetum hyemale, 25-35 parts of felwort, 10-20 parts of inula flower, 10-20 parts of chamomile flower, 10-20 parts of dianthus superbus, 6-13 parts of nux prinsepiae, 3-9 parts of dragon's blood, 3-9 parts of fructus viticis and 500-1500 parts of fresh wether liver. The Chinese medicine composition can be used for treating fundi diseases caused by any reasons, especially has a special effect of treating symptoms such as retinal arterial obstruction, retinal vein obstruction, optic neuritis, retinal detachment, macular degeneration and the like. Through repeated clinical verifications, the Chinese medicine composition is accurate in treatment effect, good in effect, short in treatment course, high in effect taking speed, and free from side and toxic effects.
Description
Technical field
The present invention relates to a kind of Chinese medicine pill for the treatment of ophthalmic, particularly a kind of Chinese medicine composition for the treatment of retinopathy and preparation method thereof.
Background technology
Optical fundus is the custom appellation in ophthalmology field.Refer to the eyeball inner tissue of the eyeball back segment that with the naked eye cannot get a glimpse of clinically, tunica uvea in the middle of comprising, vitreous body, choroid and retina, optic nerve etc.Retinopathy mainly refers to retina, the pathological changes of optic nerve at present.As retinal circulation obstacle, detachment of retina, distortion and optic nerve, amphiblestroid inflammation, the diseases such as degeneration.Retinopathy is a class commonly encountered diseases very harmful to vision on clinical ophthalmology, and many sharply oculopathy of visual deterioration all belong to the scope of retinopathy.
In flourishing industrial country, retinopathy has become the main cause of blinding.In the certain areas of China, retinopathy is also the first five position that has occupy causes of blindness.The sudden blindness disease of the traditional Chinese medical science just belongs to present retinopathy.
Western medicine has various fundus disease can cause sudden blindness disease, and the most common person is as retinal centre angiemphraxis, periphlebitis of retina and acute optic neuritis etc.Sudden blindness is many because anger is contrary to cruelly, upward invasion of liver-QI, and QI and blood closing, channels blocks; Or pathogenic fire derived from stagnation of liver-QI, hyperactivity of YANG due to deficiency of YIN, bleeding due to blood-heat, venation block; Or ponder over too, nutrient blood secretly consumes, and heart spleen two loses, and vital essence can not sending nutrient upward to eye etc. causes.
At present to this disease also without special effective Therapeutic Method, mainly with a large amount of Neurotrophic drugs and vasodilation, effect is not good enough clinically.About 3 months, occur that after being ill neovascular glaucoma can cause blind, a few patients Repeated Hemorrhage, also causes blind.Therefore people are to treatment retina, and the pathological changes of optic nerve exists this widespread demand.Up to now also not finding has eutherapeutic especially medicine report in any relevant invention compositions clinical practice.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of retinopathy, this Chinese medicine composition passes through clinical verification repeatedly, and its determined curative effect is effective, and short treating period is rapid-action, has no side effect.
The present invention also provides the preparation method of the Chinese medicine composition for the treatment of retinopathy, and preparation method is under the guidance of theory of Chinese medical science, be prepared into pill, and this Chinese medicine is through clinical verification for many years, the soothing the liver improving eyesight of energy, nourishing kidney pathogenic fire reducing, suppressing the hyperactive liver and subsiding YANG, promoting blood circulation to remove obstruction in the collateral, clearing away heat and cooling blood, the nebula removing barrier that disappears.
The object of the invention is to realize by following technical proposals.
Treat a Chinese medicine composition for retinopathy, this Chinese medicine composition is prepared from by the raw material of Chinese medicine of following mass ratio:
40-50 parts of Fel Ursis, 40-50 parts of Rhizoma Coptidis, 40-50 parts of Flos Buddlejaes, 40-50 parts of Rhizoma Et Radix Notopterygiis, 25-35 parts of Rhizoma aspidistrae luridae, 25-35 parts of Cortex Lycii, 25-35 parts of Herba Epimedii, 25-35 parts of Herba Equiseties Hiemalis, 25-35 parts of Radix Gentianaes, 10-20 parts of Flos Inulaes, 10-20 parts of Flos Chrysanthemis, 10-20 parts of Herba Dianthis, 6-13 parts of Nux Prinsepiae, 3-9 parts of Sanguis Draxonis, 3-9 parts of Fructus Viticises, 500-1500 parts of fresh wether livers.
Further, described Chinese medicine composition is prepared from by the raw material of Chinese medicine of following mass ratio:
42-48 parts of Fel Ursis, 42-48 parts of Rhizoma Coptidis, 42-48 parts of Flos Buddlejaes, 42-48 parts of Rhizoma Et Radix Notopterygiis, 28-32 parts of Rhizoma aspidistrae luridae, 28-32 parts of Cortex Lycii, 28-32 parts of Herba Epimedii, 28-32 parts of Herba Equiseties Hiemalis, 28-32 parts of Radix Gentianaes, 13-18 parts of Flos Inulaes, 13-18 parts of Flos Chrysanthemis, 13-18 parts of Herba Dianthis, 8-11 parts of Nux Prinsepiae, 4-8 parts of Sanguis Draxonis, 4-8 parts of Fructus Viticises, 800-1400 parts of fresh wether livers.
Further, described Chinese medicine composition is prepared from by the raw material of Chinese medicine of following mass ratio:
45 parts of Fel Ursis, 45 parts of Rhizoma Coptidis, 45 parts of Flos Buddlejaes, Rhizoma Et Radix Notopterygii 45 powder, 30 parts of Rhizoma aspidistrae luridae, 30 parts of Cortex Lycii, 30 parts of Herba Epimedii, 30 parts of Herba Equiseties Hiemalis, 30 parts of Radix Gentianaes, 15 parts of Flos Inulaes, 15 parts of Flos Chrysanthemis, 15 parts of Herba Dianthis, 9 parts of Nux Prinsepiae, 6 parts of Sanguis Draxonis, 6 parts of Fructus Viticises, 1250 parts of fresh wether livers.
The present invention and then provided the preparation method of the Chinese medicine composition for the treatment of retinopathy, comprises the steps:
1), first by Fel Ursi, Sanguis Draxonis, grinds respectively extremely brokenly, sieves, and obtains 120 object fine powders;
2) again Nux Prinsepiae peeling shell is got to frost, Herba Equiseti Hiemalis removes joint, Fructus Viticis is washed in a pan and is dried with well water, Rhizoma aspidistrae luridae wine is processed, then together with Rhizoma Coptidis, Flos Buddlejae, Rhizoma Et Radix Notopterygii, Cortex Lycii, Herba Epimedii, Radix Gentianae, Flos Inulae, Herba Dianthi, Flos Chrysanthemi, amount to 13 taste crude drug and pulverize respectively, sieve, obtain 80-100 object fine powders;
3) by step 1) fine powder and step 2) fine powder, mix, stir, check;
4) add fresh wether liver according to 327-466 parts of raw material of Chinese medicine medicine fine powders of above-mentioned 15 taste meter with the mass ratio of the fresh wether liver of 800-1500 part, get the fresh wether liver of above-mentioned mass fraction and clean, half is placed in pot, boil chopping with clear water, dry, grind as fine powder, stir in step 2) compositions in;
5) get the fresh wether liver of other half, striping is mashed, and adds in the compositions of step 3) and mixes pill, then dries packing warehouse-in.
Prescription of the present invention is to examine machine at Chinese medical discrimination, establish on the basis of Therapeutic Method, according to side's principle processed of ancient prescription, by selecting suitable medicine, decide suitable dosage, stipulate the suitable a series of process such as dosage form and usage, last completed treatment retinal vein, obstruction of artery, optic neuritis, retina shedding, the retinopathy such as age-related macular degeneration.
Prescription of the present invention is also after distinguishing disease, under Therapeutic Principle's guidance, and the therapeutic scheme of drafting for the etiology and pathogenesis of disease.According to theory of Chinese medical science, method for the treatment of is the foundation of use side or prescription, and prescription is the means that embody and verify method for the treatment of.Prescription uses multi-flavor medicine to some disease simultaneously, wherein certainly exists the problem of a compatibility, comprises the whether suitable of flavour of a drug, the number of figure place, the weight of component etc., the curative effect that all directly impact is brought into play the treatment of disease.
One, the combination of side is take disease as basis, and having is to demonstrate,prove system side.So-called gas has how many, and disease has prosperity and decline, treatments can be classified into mildness and intenseness according to their therapeutic speeds, and there is size side; Its two, the compatibility of concrete side's medicine, is decided by the establishment of method for the treatment of; Its three, system side whether suitable, mainly sees that whether the compatibility of the five tastes appropriate to the property of medicine four gas.As anxious intense nature and taste, slow thin nature and taste, fever and chills and warm and cool, instead from its disease.Traditional Chinese medical science prescription compatibility is particular about mutually collaborative, interacts, and changes the property of medicine thereby counteract each other, and heightens the effect of a treatment and makes it to reach the object for the treatment of ophthalmic diseases.Medicine only has single effect simply, and after compatibility, the property of medicine changes, and effect changes, and curative effect also changes, and can produce mutual synergism, strengthens therapeutic effect, expands therapeutic domain, adapts to the complicated state of an illness, reduces toxicity.The different concocting methods of effect and the different pharmaceutical consumption of medicine, also can make curative effect that very large change occurs.
Pungent sugariness medicine in this Chinese medicine composition mostly is warm drugs, belongs to sun, and effect rises floating.Picric acid saline taste medicine, mostly is cold and cool medicine, belongs to cloudy, many sedimentations.Wherein Rhizoma Et Radix Notopterygii, together with kidney-reinforcing drug compatibility, can strengthen the kidney invigorating effect, and all right priming is up, and YIN nourishing helps wet.Rhizoma aspidistrae luridae wine is processed rear solution fishy smell, has priming up, strengthens the effect of removing nebula to improve visual acuity.
Fel Ursi belongs to improving eyesight medicine, and bitter in the mouth is cold in nature, is included into liver, gallbladder, spleen, stomach warp.Energy clearing away heat and relieving spasm, improving eyesight.Heat clearing away is moved back red in conjunctival congestion and swelling pain, iridocyclitis, and photophobia is shed tears.Removing nebula to improve visual acuity is for black eyeball nebula film, pterygium, cataract.
Rhizoma Coptidis, Radix Gentianae belongs to heat clearing and dampness removing medicine, and Rhizoma Coptidis bitter in the mouth is cold in nature, is included into the heart, spleen, stomach, liver and gall, large intestine channel.Can heat clearing and damp drying, heat-clearing and toxic substances removing, clearing heart fire, clearing away heat and cooling blood.Heat clearing and damp drying is used for the damp and hot steaming of accumulateing, conjunctival congestion and swelling pain, and punctate keratitis is grown thickly, and lipoid is fertile floating tender and crisp, iridocyclitis, vitreous opacity, the multiple interior external ophthalmopathies such as eye pain inflammatory exudation edema.Heat-clearing and toxic substances removing is for the evil poison of epidemic disease, and furuncle is too fat to move, the red and swollen heating of eyelid, or hyperemia of the bulbar conjunctiva swelling.Clearing heart fire holds in heart-fire, and corner of the eyes pyorrhea, or corner of the eyes angle erosion greatly or corner of the eyes portion are red red, or ciliary hyperemia.Clearing away heat and cooling blood is for bleeding due to blood-heat, intraocular hemorrhage.Radix Gentianae bitter in the mouth, cold in nature, return and liver and gallbladder meridian.Can eliminating pathogen in the liver clearing gallbladder, for liver and gall excess-fire or damp and hot, conjunctival congestion and swelling pain, bulbar conjunctiva polyp plumpness, keratitis is fertile floating tender and crisp, hypopyon, corneal descemetocele, iridoptosis is real to be risen, iridocyclitis, optic nerve, retina inflammatory congestion and edema.
Flos Buddlejae belongs to the nebula removing barrier medicine that disappears, and sweet-bitter flavor is flat, and cold nature, is included into Liver Channel, can heat clearing away nourishing the liver, and improving acuity of vision and removing nebula.The cool liver of heat clearing away is used for liver-heat conjunctival congestion, hyperemic arterioles enlarged, and photophobia is shed tears.Removing nebula to improve visual acuity is for black eyeball cataracta, and photophobia fear day, pain is shed tears.Nourishing the liver to improve visual acuity is for hepatasthenia dim eyesight, blurring of vision, or infantile keratomalacia, nyctalopia.
Rhizoma Et Radix Notopterygii acrid in the mouth hardship, warm in nature, be included into bladder and lung meridian, energy expelling wind and cold, removing damp and stopping pain, belongs to and disperses cold medicine.Dispersing wind-cold is violated table for wind and cold, headache conjunctival congestion.Rise a nebula removing and cause nebula for ailment said due to cold or exposure, the rapid jerky some cataracta of black eyeball, a fear day photophobia.Wind-expelling pain-stopping is for wind and cold headache due to pathogenic wind-dampness, ophthalmalgia.Rise a clearing heat in QI system and sink for insufficiency of the spleen clearing heat in QI system, order loses warm, blurred vision cataract
Rhizoma aspidistrae luridae belongs to the nebula removing barrier medicine that disappears, and sweet-bitter flavor is flat, is included into lung and Liver Channel, the wind heat of faling apart, and nebula removing, expelling wind for relieving convulsion, detoxifies, the nebula of dispelling.Removing nebula to improve visual acuity is used for black eyeball the old and new nebula film, red white barrier for a long time, poor vision.Dispelling wind and relieving is for skin pruritus, eye itching, or unbearable itching.
Cortex Lycii belongs to heat removing and blood cooling medicine, and sweet in the mouth is cold in nature, is included into lung, liver, kidney channel.For clearing away heat and cooling blood, lung heat clearing pathogenic fire reducing, treatment deficiency of YIN osteopyrexia and fever, hemoptysis is spitted blood, ophthalmic Repeated Hemorrhage, poor vision, lung-fire pent-up, node of the sclera, pain is shed tears.
Herba Epimedii belongs to kidney-reinforcing drug acrid-sweet flavor, warm in nature, is included into liver and kidney channel, energy kidney-replenishing, wind-damp dispelling, bone and muscle strengthening.Kidney invigorating and YANG supporting is for kidney yang virtual loss, impotence, soreness of the waist and knees, dizzy tinnitus, optic atrohic blindness, nyctalopia.
The low-priced nebula removing barrier medicine that disappears that belongs to of wood, sweet-bitter flavor is flat, is included into lung and Liver Channel, the wind heat of faling apart, nebula removing film.Expelling wind and removing nebula is used for wind-heat of liver channel, conjunctivitis, and photophobia is shed tears.Expelling wind for arresting lacrimation is for epiphora induced by wind, not well depending on thing.Rise loose stagnated fire for stagnated fire conjunctival congestion, order does not move back for a long time.
Inula is in apophlegmatisant, and sour in the mouth is sweet, and temperature is nontoxic, enters the heart, liver, intestine and small intestine warp.Control wind syndrome of head improving eyesight, by Shui relieving constipation, remove full sensation over the precordial region fullness and hardness of the abdomen, arresting convulsion is strange, only cold and heat.
Flos Chrysanthemi sweet-bitter flavor, cold nature, is included into lung and Liver Channel.Belong to wind-dispelling heat-dissipating medicine.Wind-dispelling heat-dissipating is used for wind heat ophthalmalgia, conjunctival congestion and swelling pain, and photophobia is shed tears.Suppressing the hyperactive liver improving eyesight is partially high for liver-yang, has a headache dizzy, and blurring of vision.Nourishing the liver arresting lacrimation, for deficiency of the liver cold tears, is felt dizzy.Nebula removing disappears barrier for pterygium, cataract.
Herba Dianthi belongs to sharp Shui eliminating dampness by diuresis flavour of a drug hardship, cold in nature, is included into the heart and small intestine meridian.Clear water heat conduction is held in heart-fire, ciliary hyperemia difficulty and pain in micturition.Eliminating damp-heat is used for damp and hot conjunctival congestion, the raw nebula of black eyeball.
Nux Prinsepiae belongs to nourishing the liver and kidney medicine, sweet in the mouth, cold nature, is included into Liver Channel, can nourishing the liver to improve visual acuity for hepatasthenia dim eyesight, can not hypermetropia, time flow cold tears.Wind-dispelling heat-dissipating is for wind-heat of liver channel, and nebula film hides pupil, and the swollen corner of the eyes of order is rotten.
Sanguis Draxonis belongs to drug for invigorating blood circulation and eliminating stasis.Sweet-salty, property is flat, is included into the heart and Liver Channel, energy blood circulation promoting and blood stasis dispelling, blood stasis dispelling analgesic therapy, hemostasia and promoting granulation.Blood stasis dispelling analgesic therapy is for mechanical ocular injury, and eyelid congestion swells and ache, and hyphema is not loose, hurt like hell.
Fructus Viticis, acrid in the mouth hardship, cold nature, is included into bladder, liver, kidney channel, belongs to wind-dispelling heat-dissipating medicine.Wind-dispelling heat-dissipating is for conjunctival congestion and swelling pain.Dispelling wind and relieving is used for headache due to pathogenic wind-heat, eye socket pain, pain of supra-orbital ridge.Dispelling wind nebula removing is for wind heat oculopathy.
Wether liver, the liver that refers to be castrated rear ram.Sweet, hardship, cool, enter Liver Channel, beneficial blood, tonifying liver, improving eyesight.Belong to hematonic, for blood deficiency and yellow complexion, deficiency of the liver, nyctalopia, hides from view, optic atrohic blindness.
This Chinese medicine composition is by Fel Ursi clearing away heat to improve acuity of vision, Flos Chrysanthemi wind-dispelling heat-dissipating, suppressing the hyperactive liver improving eyesight.Fructus Viticis wind-dispelling heat-dissipating, the clear sharp head.Rhizoma Et Radix Notopterygii rises and sends out nebula removing, wind-expelling pain-stopping.Cortex Lycii removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing.Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication.Radix Gentianae heat clearing and damp drying, eliminating pathogen in the liver clearing gallbladder.Herba Dianthi inducing diuresis for treating stranguria syndrome, removing blood stasis stimulates the menstrual flow.Sanguis Draxonis is invigorated blood circulation and is cured the wound, blood stasis dispelling analgesic therapy, hemostasia and promoting granulation.Nux Prinsepiae nourishing the liver to improve visual acuity, wind-dispelling heat-dissipating.Flos Inulae therapeutic method to keep the adverse QI flowing downwards row water, eliminating phlegm and softening indurated mass.Herba Epimedii kidney-replenishing, wind-damp dispelling, bone and muscle strengthening.Rhizoma aspidistrae luridae dispels the wind, arresting convulsion, removing toxic substances, nebula removing.Herba Equiseti Hiemalis's wind heat nebula removing film that falls apart.Flos Buddlejae heat clearing away nourishing the liver, improving acuity of vision and removing nebula.Wether liver benefit blood, tonifying liver, improving eyesight.
Flos Chrysanthemi in this Chinese medicine composition and the Herba Equiseti Hiemalis's compatibility energy nebula removing barrier that disappears, Fructus Viticis and Flos Chrysanthemi compatibility energy wind-dispelling heat-dissipating, dispelling wind nebula removing, Rhizoma Et Radix Notopterygii and Flos Chrysanthemi compatibility can rise sends out a nebula removing, and it is up that Rhizoma Et Radix Notopterygii and Herba Epimedii compatibility both can priming, can YIN nourishing help wet again.Rhizoma Coptidis and Radix Gentianae compatibility energy heat clearing and damp drying.Rhizoma aspidistrae luridae and Herba Equiseti Hiemalis, Flos Buddlejae compatibility energy removing nebula to improve visual acuity.Herba Equiseti Hiemalis and Rhizoma aspidistrae luridae compatibility energy expelling wind and removing nebula.Flos Buddlejae and Flos Chrysanthemi, Herba Equiseti Hiemalis's compatibility energy removing nebula to improve visual acuity.Energy heat clearing away nebula removing after wether liver and Rhizoma Coptidis compatibility, improving eyesight.After the combination and compatibility of scientific and precise, there is the variation of essence in drug effect, can soothing the liver improving eyesight, and nourishing kidney pathogenic fire reducing, suppressing the hyperactive liver and subsiding YANG, promoting blood circulation to remove obstruction in the collateral, clearing away heat and cooling blood, the nebula removing barrier that disappears.
After all medicine compatibilities of above 16 taste, the collaborative superposition of each medicine manifests completely, makes medicine give full play to greatest treatment efficacy, plays soothing the liver improving eyesight, nourishing kidney pathogenic fire reducing, suppressing the hyperactive liver and subsiding YANG, promoting blood circulation to remove obstruction in the collateral, clearing away heat and cooling blood, nebula removing disappear barrier effect.To treatment retinal artery occlusion, the retinal vein occlusion, optic neuritis, detachment of retina, the diseases such as age-related macular degeneration have specially good effect, have short treating period, instant effect, double the effecting a permanent cure of taking stopgap measures, side effect is little, the feature such as after controlling, does not recur.
According to theory of Chinese medical science, monarch drug: the medicine that plays therapeutical effect for main disease or primary symptom.Ministerial drug: the medicine that plays primary treatment effect for hold concurrently disease or double disease.Adjuvant drug: implication has three: one, is used for the treatment of the medicine of less important double disease, and the 2nd, eliminate and alleviate the monarch and his subjects' toxicity or strong medicine, the 3rd, need to select the medicine that can work again the effect of coordinating contrary to monarch drug nature and flavor according to the state of an illness.Make medicine: implication has two: one, the through sick institute of the efficacy of a drug that can guiding side's Chinese medicine, the 2nd, interaction that can coordinating the actions of various ingredients in a prescription.
This Chinese medicine composition is in order to give full play to the effect for the treatment of by Chinese herbs disease, and overcomes some toxic reaction, guarantees safety, reaches greatest treatment efficacy, need to be carefully dished up.Though such as some drugs has good curative effect, also exist certain Side effect, can reduce or eliminate Side effect by concocting, make to reach set curative effect after taking, have and be unlikely to have side effects.As raw in Radix Aconiti Kusnezoffii with being large poison, after concocting with bean curd, toxicity significantly reduces.Make each medicine ratio of compositions accurate, the main concocting method that uses clean system.
In prescription of the present invention, Herba Equiseti Hiemalis removes joint, and Nux Prinsepiae clip is got frost, and fresh wether liver striping, removes its invalid drug moiety, retains effective part, thereby makes medicine reach greatest treatment efficacy.Chinese medicine is through heating, water is washed in a pan, wine is washed, process, fry, dry wait concoct processing after, make the physicochemical property of some drugs produce variation in various degree, some compositions are out dissolved, and some compositions are decomposed or change into new composition, all these all can the centering medicine property of medicine and curative effect produce impact in various degree.Because the Chinese medicine that forms Chinese patent medicine is usually to multiple internal organs, meridians have effect, play a role in order to make medicine concentrate on diseased region, often add the method for adjuvant to concoct, strengthen its effect to diseased region, weaken the effect to irrelevant position, the therapeutical effect of outstanding Chinese patent medicine to main dirty main internal organs.
Fructus Viticis (well water is washed in a pan) in this Chinese medicine composition, after Rhizoma aspidistrae luridae (wine is processed), the property of medicine is fully brought into play, reduces side effects of pharmaceutical drugs, makes drug effect reach greatest treatment efficacy.Due to a normally medicine multiple-effect of Chinese medicine, in different Chinese patent medicines, the effect that same medicine is required is also different, must concoct medicine wherein, adjusts its property of medicine, brings into play it and is good at.Thereby the process of preparing Chinese medicine can change the lifting of medicine and change the property of medicine.Lifting sink-float is to show the trend of drug effect in the time of body.
Feature of the present invention is:
1. the choice criteria of medicine: nontoxic, without mould, without worm, aseptic, pollution-free, free from admixture.
2. grasp four property: have four gas, i.e. four kinds of property of medicine of fever and chills and warm and cool of title.
3. strict implement medication taboo: by (nineteen medicaments of mutual restraint song) strict implement.
4. the compatibility standard of strict implement medication: according to present senior compatibility, monarch, minister, assistant, the combination principle making.Monarch drug is Fel Ursi, and ministerial drug is Nux Prinsepiae, Herba Epimedii, and Rhizoma aspidistrae luridae, Cortex Lycii, Fructus Viticis, Sanguis Draxonis, adjuvant drug is Flos Buddlejae, Flos Chrysanthemi, Radix Gentianae, Rhizoma Coptidis, making medicine is wether liver, Rhizoma Et Radix Notopterygii, Flos Inulae, Herba Dianthi, Herba Equiseti Hiemalis.Adhere to mutually coordinating in compatibility, respectively get the chief, the principle of opposing each other and yet also complement each other.Complementary compatibility consumption in strict grasp compatibility, to give full play to drug effect.
5. in strict accordance with the traditional concocting method of the traditional Chinese medical science, Zheng Pao Shaved refines.
Feature of the present invention has extensively compared with similar drugs, strange, strong three large outstanding features, can treat the retinopathy that any reason causes, especially to treatment retinal artery occlusion, the retinal vein occlusion, optic neuritis, detachment of retina, the diseases such as age-related macular degeneration have specially good effect.
The present invention has distinct characteristic, takes rear instant effect, short treating period, and curative effect is high, and side effect is little, treating both the principal and secondary aspects of a disease, taking convenience.
1. wide---what is called is exactly extensively to select famous and precious animal drugs and Chinese herbal medicine, as Fel Ursi belongs to improving eyesight medicine, after the mutual compatibility of Chinese herbal medicine, can soothing the liver improving eyesight, nourishing kidney pathogenic fire reducing, suppressing the hyperactive liver and subsiding YANG, promoting blood circulation to remove obstruction in the collateral, eliminate stagnation and dissolve phlegm, clearing away heat and cooling blood, the nebula removing barrier that disappears.Give prominence to Chinese medicine, monarch, minister, assistant, makes ingenious compatibility, makes it to give full play to greatest treatment efficacy.
2. strange:---be exactly the Chinese herbal medicine that we select, mutually after compatibility, changed the property of medicine, medicine can be given full play to greatest treatment efficacy, as Rhizoma Et Radix Notopterygii is medicine effect, can deliver cold expelling, rise and send out nebula removing, and can strengthen the kidney invigorating effect after Herba Epimedii compatibility, all right priming is up, and YIN nourishing helps wet.
3. strong:---so-called is exactly function and the effect of concentrating medicine by force, completely according to theory of Chinese medical science monarch, minister, assistant, the senior combination principle making, with monarch, minister is main, assistant, it is auxiliary making, and makes it reach maximum, best curative effect.
The present invention is by 16 taste Chinese medicine science compatibilities, and treatment retinopathy is had to good curative effect.Use after a course for the treatment of of the present invention to arteria retina vein obstruction effective percentage 99%, optic neuritis effective percentage 99%, retina shedding effective percentage 99%, age-related macular degeneration effective percentage 99%.
The specific embodiment
Chinese medicine composition and the preparation method of the present invention being treated to retinopathy below in conjunction with example are described further.
Embodiment 1
Take respectively Fel Ursi 40g, Rhizoma Coptidis 40g, Flos Buddlejae 40g, Rhizoma Et Radix Notopterygii 40g, Rhizoma aspidistrae luridae 25g, Cortex Lycii 25g, Herba Epimedii 25g, Herba Equiseti Hiemalis 25g, Radix Gentianae 25g, Flos Inulae 10g, Flos Chrysanthemi 10g, Herba Dianthi 10g, Nux Prinsepiae 6g, Sanguis Draxonis 3g, Fructus Viticis 3g, fresh wether liver 500g;
1), first by the Fel Ursi of above-mentioned quality, Sanguis Draxonis, grinds respectively extremely brokenly, sieves, and obtains 120 object fine powders;
2) again the Nux Prinsepiae of above-mentioned quality peeling shell is got to frost, Herba Equiseti Hiemalis removes joint, Fructus Viticis is washed in a pan and is dried with well water, Rhizoma aspidistrae luridae wine is processed, then together with Rhizoma Coptidis, Flos Buddlejae, Rhizoma Et Radix Notopterygii, Cortex Lycii, Herba Epimedii, Radix Gentianae, Flos Inulae, Herba Dianthi, Sanguis Draxonis, Flos Chrysanthemi, amount to 13 taste crude drug and pulverize respectively, sieve, obtain 80-100 object fine powders;
3) step 1) fine powder and step 2) fine powder, mix, stir, check;
4) then get an above-mentioned quality fresh wether liver clean, half is placed in pot, boils chopping with proper amount of clear water, dries, and grinds as fine powder, stirs in step 2) compositions in;
5) other one half a lifetime wether liver striping mash, add and in compositions, mix pill, then dry packing warehouse-in.
Embodiment 2
Take respectively Fel Ursi 50g, Rhizoma Coptidis 50g, Flos Buddlejae 50g, Rhizoma Et Radix Notopterygii 50g, Rhizoma aspidistrae luridae 35g, Cortex Lycii 35g, Herba Epimedii 35g, Herba Equiseti Hiemalis 35g, Radix Gentianae 35g, Flos Inulae 20g, Flos Chrysanthemi 20g, Herba Dianthi 20g, Nux Prinsepiae 13g, Sanguis Draxonis 9g, Fructus Viticis 9g, fresh wether liver 1500g.
Its preparation method is with embodiment 1.
Embodiment 3
Take respectively Fel Ursi 45g, Rhizoma Coptidis 45g, Flos Buddlejae 45g, Rhizoma Et Radix Notopterygii 45g, Rhizoma aspidistrae luridae 30g, Cortex Lycii 30g, Herba Epimedii 30g, Herba Equiseti Hiemalis 30g, Radix Gentianae 30g, Flos Inulae 15g, Flos Chrysanthemi 15g, Herba Dianthi 15g, Nux Prinsepiae 9g, Sanguis Draxonis 6g, Fructus Viticis 6g, fresh wether liver 1250g.
Its preparation method is with embodiment 1.
Embodiment 4
Take respectively Fel Ursi 48g, Rhizoma Coptidis 48g, Flos Buddlejae 48g, Rhizoma Et Radix Notopterygii 48g, Rhizoma aspidistrae luridae 32g, Cortex Lycii 32g, Herba Epimedii 32g, Herba Equiseti Hiemalis 32g, Radix Gentianae 32g, Flos Inulae 18g, Flos Chrysanthemi 18g, Herba Dianthi 18g, Nux Prinsepiae 11g, Sanguis Draxonis 8g, Fructus Viticis 8g, fresh wether liver 1100g.
Its preparation method is with embodiment 1.
Embodiment 5
Take respectively Fel Ursi 42g, Rhizoma Coptidis 42g, Flos Buddlejae 42g, Rhizoma Et Radix Notopterygii 42g, Rhizoma aspidistrae luridae 28g, Cortex Lycii 28g, Herba Epimedii 28g, Herba Equiseti Hiemalis 28g, Radix Gentianae 28g, Flos Inulae 13g, Flos Chrysanthemi 13g, Herba Dianthi 13g, Nux Prinsepiae 8g, Sanguis Draxonis 5g, Fructus Viticis 4g, fresh wether liver 800g.
Its preparation method is with embodiment 1.
Clinical efficacy of the present invention is as follows:
One, case 500 examples, wherein: arteria retina, vein backup 120 examples, optic neuritis 110 examples, retina shedding 105 examples, age-related macular degeneration 165 examples.
Two, symptom:
Arteria retina, vein obstruction: vision rapid drawdown, the pupil is loose large, intraocular hemorrhage.
Optic neuritis: vision rapid drawdown, eyeball portion pain, platycoria.
Detachment of retina: ophthalmic flash of light sense, appears muscae volitantes shape, in vision rapid drawdown.
Age-related macular degeneration: visual deterioration, metamorphopsia.
Three, instructions of taking:
Make pill by proportioning, as Semen Firmianae large (0.2g), send down with rice drink after meal, 30 balls, three times on the one 20 days is a course for the treatment of.
Four, the course for the treatment of standard:
Cure:
Arteria retina, vein obstruction: vision restoration is normal, it is normal that the pupil recovers, and ophthalmic is without hemorrhage.
Optic neuritis: vision restoration is normal, eyeball portion pain disappears, and it is normal that pupil recovers.
Retina shedding: vision restoration is normal, muscae volitantes shape disappears, and ophthalmic flash of light sense disappears.
Age-related macular degeneration: vision restoration is normal, metamorphopsia disappears.
Effective:
Arteria retina, vein obstruction: vision is recovered to some extent, the pupil is loose to be reduced greatly, and intraocular hemorrhage amount reduces.
Optic neuritis: vision is recovered to some extent, eyeball portion pain relief, pupil diminishes.
Retina shedding: vision is recovered to some extent, muscae volitantes shape reduces, and ophthalmic is light sensation slightly.
Age-related macular degeneration: vision is recovered to some extent, metamorphopsia reduces.
Invalid:
Arteria retina, vein obstruction: symptom is without change.
Optic neuritis: symptom is without change.
Retina shedding: symptom is without change.
Age-related macular degeneration: symptom is without change.
Four, therapeutic outcome (in table 1)
Case is as follows:
Example 1: Li Xiulan, female, 65 years old, suffer from hypertension 10 years, belong to slight moderate vein, obstruction of artery at local ophthalmologic examination.Vision rapid drawdown before January, ophthalmic has hemorrhage, does not see Chu's things.Check that optical fundus pupil god has slight loose large.In Shaanxi Province, ophthalmologic hospital therapeutic effect is not good enough.After take 1 course for the treatment of of this medicine, can see leaves, check that retinal hemorrhage amount disappears in a large number.Continue to take the course for the treatment of half, vision has been recovered recovery from illness, can know and see and remove ophthalmologic examination by things, and it is normal that retinal hemorrhage and mydriasis have recovered.
Example 2: Zhao Mingren, man, 60 years old, suffered from the past high myopia, often there is muscae volitantes shape and flash of light at the moment in the nearly section time, examination of ocular fundus is diagnosed as primary detachment of retina.After local hospital treatment, symptom takes a turn for the better to some extent, before 5 days, has and increases the weight of suddenly, sees that thing is extremely smudgy.After take one course for the treatment of of this medicine, can see large word, muscae volitantes shape and aethomma disappear to some extent, then continue to take after the course for the treatment of, eyes have recovered normally, can know and see things, muscae volitantes shape and flash of light at the moment disappears completely.Inspection optical fundus has recovered normal.
Example 3: Cui Lili, female, 68 years old, to suffer from hypertension and cerebrovascular and have 8 years, before February, eyes do not see suddenly, indistinctly see things distortion, and examination of ocular fundus has retina deep hemorrhage and atrophy focus on a large scale.Hospital is diagnosed as senile degeneration of macula.At hospitalize first quarter moon, effect is unsatisfactory.Eyes do not see Chu's things often.Introduce and take half course for the treatment of of this medicine by others, can see the large word of writing, continue to take a course for the treatment of.It is normal that eyes recover, and can know and see things, and things distortion disappears, and it is normal that examination of ocular fundus has recovered.
Claims (4)
1. a Chinese medicine composition for the treatment of retinopathy, is characterized in that, this Chinese medicine composition is prepared from by the raw material of Chinese medicine of following mass ratio:
40-50 parts of Fel Ursis, 40-50 parts of Rhizoma Coptidis, 40-50 parts of Flos Buddlejaes, 40-50 parts of Rhizoma Et Radix Notopterygiis, 25-35 parts of Rhizoma aspidistrae luridae, 25-35 parts of Cortex Lycii, 25-35 parts of Herba Epimedii, 25-35 parts of Herba Equiseties Hiemalis, 25-35 parts of Radix Gentianaes, 10-20 parts of Flos Inulaes, 10-20 parts of Flos Chrysanthemis, 10-20 parts of Herba Dianthis, 6-13 parts of Nux Prinsepiae, 3-9 parts of Sanguis Draxonis, 3-9 parts of Fructus Viticises, 500-1500 parts of fresh wether livers.
2. a kind of Chinese medicine composition for the treatment of retinopathy according to claim 1, is characterized in that, described Chinese medicine composition is prepared from by the raw material of Chinese medicine of following mass ratio:
42-48 parts of Fel Ursis, 42-48 parts of Rhizoma Coptidis, 42-48 parts of Flos Buddlejaes, 42-48 parts of Rhizoma Et Radix Notopterygiis, 28-32 parts of Rhizoma aspidistrae luridae, 28-32 parts of Cortex Lycii, 28-32 parts of Herba Epimedii, 28-32 parts of Herba Equiseties Hiemalis, 28-32 parts of Radix Gentianaes, 13-18 parts of Flos Inulaes, 13-18 parts of Flos Chrysanthemis, 13-18 parts of Herba Dianthis, 8-11 parts of Nux Prinsepiae, 4-8 parts of Sanguis Draxonis, 4-8 parts of Fructus Viticises, 800-1400 parts of fresh wether livers.
3. a kind of Chinese medicine composition for the treatment of retinopathy according to claim 1, is characterized in that, described Chinese medicine composition is prepared from by the raw material of Chinese medicine of following mass ratio:
45 parts of Fel Ursis, 45 parts of Rhizoma Coptidis, 45 parts of Flos Buddlejaes, Rhizoma Et Radix Notopterygii 45 powder, 30 parts of Rhizoma aspidistrae luridae, 30 parts of Cortex Lycii, 30 parts of Herba Epimedii, 30 parts of Herba Equiseties Hiemalis, 30 parts of Radix Gentianaes, 15 parts of Flos Inulaes, 15 parts of Flos Chrysanthemis, 15 parts of Herba Dianthis, 9 parts of Nux Prinsepiae, 6 parts of Sanguis Draxonis, 6 parts of Fructus Viticises, 1250 parts of fresh wether livers.
4. a preparation method for the Chinese medicine composition based on treatment retinopathy claimed in claim 1, is characterized in that, the method comprises the steps:
1), first by Fel Ursi, Sanguis Draxonis, grinds respectively extremely brokenly, sieves, and obtains 120 object fine powders;
2) again Nux Prinsepiae peeling shell is got to frost, Herba Equiseti Hiemalis removes joint, Fructus Viticis is washed in a pan and is dried with well water, Rhizoma aspidistrae luridae wine is processed, then together with Rhizoma Coptidis, Flos Buddlejae, Rhizoma Et Radix Notopterygii, Cortex Lycii, Herba Epimedii, Radix Gentianae, Flos Inulae, Herba Dianthi, Flos Chrysanthemi, amount to 13 taste crude drug and pulverize respectively, sieve, obtain 80-100 object fine powders;
3) by step 1) fine powder and step 2) fine powder, mix, stir, check;
4) add fresh wether liver according to 327-466 parts of raw material of Chinese medicine medicine fine powders of above-mentioned 15 taste meter with the mass ratio of the fresh wether liver of 800-1500 part, get the fresh wether liver of above-mentioned mass fraction and clean, half is placed in pot, boil chopping with clear water, dry, grind as fine powder, stir in step 2) compositions in;
5) get the fresh wether liver of other half, striping is mashed, and adds in the compositions of step 3) and mixes pill, then dries packing warehouse-in.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104523981A (en) * | 2015-01-26 | 2015-04-22 | 王延林 | Traditional Chinese medicine preparation for treating optic neuritis and preparation method |
| CN115154580A (en) * | 2022-08-15 | 2022-10-11 | 左志琴 | Traditional Chinese medicine composition for treating corneal pannus, medicine and medicine preparation method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104523981A (en) * | 2015-01-26 | 2015-04-22 | 王延林 | Traditional Chinese medicine preparation for treating optic neuritis and preparation method |
| CN115154580A (en) * | 2022-08-15 | 2022-10-11 | 左志琴 | Traditional Chinese medicine composition for treating corneal pannus, medicine and medicine preparation method |
| CN115154580B (en) * | 2022-08-15 | 2023-12-26 | 左志琴 | Traditional Chinese medicine composition for treating corneal pannus, medicine and preparation method of medicine |
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Application publication date: 20140507 |