CN103764818B - 用于重组产生藏红花化合物的方法和物质 - Google Patents

用于重组产生藏红花化合物的方法和物质 Download PDF

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CN103764818B
CN103764818B CN201280038874.5A CN201280038874A CN103764818B CN 103764818 B CN103764818 B CN 103764818B CN 201280038874 A CN201280038874 A CN 201280038874A CN 103764818 B CN103764818 B CN 103764818B
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crocetin
host cell
seq
amino acid
nucleic acid
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CN103764818A (zh
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沙拉姆·拉加万
约恩·汉森
赛伦德拉·松卡尔
萨西什·库马尔
卡利安·K·库马尔
穆拉利·潘沙佩奇萨
埃斯本·哈尔克耶尔·汉森
克拉夫斯·里谢德·汉森
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Evolva AG
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CN201280038874.5A 2011-08-08 2012-08-07 用于重组产生藏红花化合物的方法和物质 Expired - Fee Related CN103764818B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161521171P 2011-08-08 2011-08-08
US61/521,171 2011-08-08
US201161576460P 2011-12-16 2011-12-16
US61/576,460 2011-12-16
US201261595450P 2012-02-06 2012-02-06
US61/595,450 2012-02-06
PCT/IB2012/001513 WO2013021261A2 (en) 2011-08-08 2012-08-07 Methods and materials for recombinant production of saffron compounds

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CN103764818A CN103764818A (zh) 2014-04-30
CN103764818B true CN103764818B (zh) 2017-05-31

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US (2) US20140248668A1 (https=)
EP (1) EP2742131B1 (https=)
JP (1) JP6126597B2 (https=)
KR (2) KR101815063B1 (https=)
CN (1) CN103764818B (https=)
AU (1) AU2012293402B2 (https=)
BR (1) BR112014002924A2 (https=)
CA (1) CA2843549A1 (https=)
HK (1) HK1199286A1 (https=)
IN (1) IN2014CN01129A (https=)
RU (1) RU2676730C2 (https=)
WO (1) WO2013021261A2 (https=)

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SG10201807693YA (en) * 2014-03-07 2018-10-30 Evolva Sa Methods for recombinant production of saffron compounds
EP3134539A1 (en) * 2014-04-25 2017-03-01 Evolva SA Methods for recombinant production of saffron compounds
CN106795477A (zh) * 2014-05-16 2017-05-31 中央研究院 用以制备虾红素的重组多核苷酸序列及其应用
CN107075522A (zh) * 2014-07-23 2017-08-18 国家新技术、能源和可持续经济发展局(Enea) 类胡萝卜素双加氧酶和在微生物和植物中以生物技术制备衍生自藏红花的化合物的方法
CA2957331A1 (en) 2014-08-11 2016-02-18 Evolva Sa Production of steviol glycosides in recombinant hosts
CA2960693A1 (en) * 2014-09-09 2016-03-17 Evolva Sa Production of steviol glycosides in recombinant hosts
EP3250686A1 (en) 2015-01-30 2017-12-06 Evolva SA Production of steviol glycosides in recombinant hosts
WO2016146711A1 (en) 2015-03-16 2016-09-22 Dsm Ip Assets B.V. Udp-glycosyltransferases
MX2018001620A (es) 2015-08-07 2018-06-11 Evolva Sa Produccion de glucosidos de esteviol en hospedadores recombinantes.
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US10982249B2 (en) 2016-04-13 2021-04-20 Evolva Sa Production of steviol glycosides in recombinant hosts
EP3458599A1 (en) 2016-05-16 2019-03-27 Evolva SA Production of steviol glycosides in recombinant hosts
CN105779406B (zh) * 2016-05-25 2019-06-18 新疆农业科学院经济作物研究所 一种藏红花酸糖基转移酶及其编码基因与应用
CN105950493B (zh) * 2016-05-25 2019-12-27 天津大学 一种工程菌及其构建方法与在制备藏红花酸中的应用
CN105950580B (zh) * 2016-05-25 2019-03-08 新疆农业科学院经济作物研究所 一种制备蛋白质UGTCs4的方法
CN109790513B (zh) * 2016-07-19 2023-04-18 科纳根公司 用于特定天然辣椒素的微生物产生的方法
WO2018083338A1 (en) 2016-11-07 2018-05-11 Evolva Sa Production of steviol glycosides in recombinant hosts
CN108728477B (zh) * 2017-04-24 2022-02-22 华东理工大学 一种高效的转座突变系统及构建方法
IT201700089843A1 (it) * 2017-08-03 2019-02-03 Enea Agenzia Naz Per Le Nuove Tecnologie Lenergia E Lo Sviluppo Economico Sostenibile Geni e metodi per la produzione e compartimentazione biotecnologica di apocarotenoidi ad elevato valore aggiunto
CN110791510A (zh) * 2018-08-02 2020-02-14 中国医学科学院药用植物研究所 一种参与西红花酸合成的乙醛脱氢酶编码基因的筛选鉴定及应用
EP3878954A4 (en) * 2018-11-07 2022-10-26 Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences ENZYME FOR THE BIOSYNTHESIS OF CROCIN AND USE THEREOF
EP3877519B1 (en) 2018-11-09 2026-03-11 Ginkgo Bioworks, Inc. Biosynthesis of mogrosides
CN109943493B (zh) * 2019-04-17 2021-05-18 天津大学 实现通用酶催化功能多样性的突变体菌株及其构建方法
KR102335035B1 (ko) * 2019-09-17 2021-12-06 아주대학교 산학협력단 효소반응을 이용한 크로신-4의 생산방법
EP4151732A1 (en) * 2021-09-15 2023-03-22 Universidad de Castilla-La Mancha Transgenic plants producing high levels of apocarotenoids compounds and uses thereof
CN116083288B (zh) * 2022-11-11 2025-02-18 泸州品创科技有限公司 产2,3-二氢-2,2,6-三甲基苯甲醛的肠膜明串珠菌及其应用
KR20250075325A (ko) * 2023-11-21 2025-05-28 아주대학교산학협력단 크로신 및 전구체 생산용 재조합 효모
CN118546994B (zh) * 2024-06-18 2025-01-28 华南农业大学 一种在种子胚乳生产藏红花素的转基因育种方法

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WO2013021261A2 (en) 2013-02-14
RU2014109010A (ru) 2015-09-20
WO2013021261A3 (en) 2013-05-02
EP2742131A2 (en) 2014-06-18
BR112014002924A2 (pt) 2018-10-09
AU2012293402A1 (en) 2014-02-06
US20170306376A1 (en) 2017-10-26
JP6126597B2 (ja) 2017-05-10
IN2014CN01129A (https=) 2015-04-10
JP2014524246A (ja) 2014-09-22
CN103764818A (zh) 2014-04-30
US20140248668A1 (en) 2014-09-04
AU2012293402B2 (en) 2017-08-03
KR20180004306A (ko) 2018-01-10
EP2742131B1 (en) 2018-11-28
CA2843549A1 (en) 2013-02-14
KR20140057319A (ko) 2014-05-12
KR101815063B1 (ko) 2018-01-05
KR101983115B1 (ko) 2019-05-29
RU2676730C2 (ru) 2019-01-10
HK1199286A1 (en) 2015-06-26

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