CN103756983B - 一种天然哺乳动物尿酸酶制备方法 - Google Patents
一种天然哺乳动物尿酸酶制备方法 Download PDFInfo
- Publication number
- CN103756983B CN103756983B CN201410015218.4A CN201410015218A CN103756983B CN 103756983 B CN103756983 B CN 103756983B CN 201410015218 A CN201410015218 A CN 201410015218A CN 103756983 B CN103756983 B CN 103756983B
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- CN
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- Prior art keywords
- urikoxidase
- damping fluid
- solution
- uricase
- buffer solution
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0044—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7)
- C12N9/0046—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7) with oxygen as acceptor (1.7.3)
- C12N9/0048—Uricase (1.7.3.3)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y107/00—Oxidoreductases acting on other nitrogenous compounds as donors (1.7)
- C12Y107/03—Oxidoreductases acting on other nitrogenous compounds as donors (1.7) with oxygen as acceptor (1.7.3)
- C12Y107/03003—Factor-independent urate hydroxylase (1.7.3.3), i.e. uricase
Abstract
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CN201410015218.4A CN103756983B (zh) | 2014-01-10 | 2014-01-10 | 一种天然哺乳动物尿酸酶制备方法 |
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CN201410015218.4A CN103756983B (zh) | 2014-01-10 | 2014-01-10 | 一种天然哺乳动物尿酸酶制备方法 |
Publications (2)
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CN103756983A CN103756983A (zh) | 2014-04-30 |
CN103756983B true CN103756983B (zh) | 2014-12-10 |
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CN201410015218.4A Active CN103756983B (zh) | 2014-01-10 | 2014-01-10 | 一种天然哺乳动物尿酸酶制备方法 |
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Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108226263B (zh) * | 2016-12-14 | 2022-03-08 | 沈阳三生制药有限责任公司 | 一种尿酸氧化酶的毛细管等电聚焦检测方法 |
CN109852623B (zh) * | 2019-02-15 | 2022-03-15 | 张文宇 | 一种peg修饰的重组人源化尿酸氧化酶的制备方法、纯化方法及其用途 |
CN114438047A (zh) * | 2020-11-05 | 2022-05-06 | 重庆派金生物科技有限公司 | 制备聚乙二醇修饰的尿酸氧化酶的方法 |
CN117327673A (zh) * | 2023-10-16 | 2024-01-02 | 临沂大学 | 一种高活性哺乳动物尿酸氧化酶突变体 |
CN117603934A (zh) * | 2023-11-30 | 2024-02-27 | 江苏恰瑞生物科技有限公司 | 一种尿酸酶的纯化方法 |
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CN102051348B (zh) * | 2009-10-27 | 2012-10-03 | 重庆富进生物医药有限公司 | 人源化重组尿酸酶及其突变体 |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
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TR01 | Transfer of patent right |
Effective date of registration: 20190808 Address after: 276500 No. 1 Yantai Road, Juxian Economic Development Zone, Rizhao City, Shandong Province Patentee after: SHANDONG RENRUI BIOTECHNOLOGY CO., LTD. Address before: 276000 Shandong province Lanshan District Linyi City Double Ridge Road Middle Linyi University Patentee before: Linyi University |
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PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A preparation method of natural mammalian uricase Effective date of registration: 20210915 Granted publication date: 20141210 Pledgee: Bank of Rizhao Co.,Ltd. Juxian sub branch Pledgor: SHANDONG RENRUI BIOTECHNOLOGY Co.,Ltd. Registration number: Y2021980009397 |