CN103750291A - Preparation method of Chinese wolfberry tablet for liver protection - Google Patents
Preparation method of Chinese wolfberry tablet for liver protection Download PDFInfo
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- CN103750291A CN103750291A CN201310572437.8A CN201310572437A CN103750291A CN 103750291 A CN103750291 A CN 103750291A CN 201310572437 A CN201310572437 A CN 201310572437A CN 103750291 A CN103750291 A CN 103750291A
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- 239000011248 coating agent Substances 0.000 claims abstract description 17
- 238000002156 mixing Methods 0.000 claims abstract description 16
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- 238000000034 method Methods 0.000 claims abstract description 9
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- 239000000284 extract Substances 0.000 claims description 5
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- XACHQDDXHDTRLX-GMPBGBGESA-N Physalien Natural products O=C(O[C@H]1CC(C)(C)C(/C=C/C(=C\C=C\C(=C/C=C/C=C(\C=C\C=C(/C=C/C=2C(C)(C)C[C@H](OC(=O)CCCCCCCCCCCCCCC)CC=2C)\C)/C)\C)/C)=C(C)C1)CCCCCCCCCCCCCCC XACHQDDXHDTRLX-GMPBGBGESA-N 0.000 description 1
- 244000197580 Poria cocos Species 0.000 description 1
- 235000008599 Poria cocos Nutrition 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
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- 229960003237 betaine Drugs 0.000 description 1
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- 238000007654 immersion Methods 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229940099908 multivitamin and calcium Drugs 0.000 description 1
- 229930184989 physalin Natural products 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P20/00—Coating of foodstuffs; Coatings therefor; Making laminated, multi-layered, stuffed or hollow foodstuffs
- A23P20/10—Coating with edible coatings, e.g. with oils or fats
- A23P20/12—Apparatus or processes for applying powders or particles to foodstuffs, e.g. for breading; Such apparatus combined with means for pre-moistening or battering
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a preparation method of a Chinese wolfberry tablet for liver protection. The method comprises the following steps: (1) masterbatch granulation of the anti-liver tablet; (2) preparation of a coating masterbatch; (3) mixing; (4) tabletting; and (5) coating. The method employs Chinese wolfberry as a main raw material, which is added with some auxiliary materials to prepare a health food with auxiliary protection function on chemical liver injury; the tablet can effectively prevent and treat fatty liver; after administration, fatty liver patients recover from a severe condition to a moderate condition, or from a moderate condition to a mild condition; therefore, the Chinese wolfberry tablet for liver protection has obvious benefits for improving liver function of the human body and shows broad market prospect.
Description
Technical field
The invention belongs to medicines and health protection field, relate to a kind of preparation method of matrimony vine liver-protecting tablet.
Background technology
Matrimony vine function with cure mainly nourishing liver and kidney, benefiting shrewd head.For consumptive disease essence, lose, soreness of waist and knee joint, dizzy tinnitus, interior heat is quenched one's thirst, and the deficiency of blood is sallow, and blurred vision is not clear.In the fruit of Chinese wolfberry, contain 14 seed amino acids, and contain the special dietary compositions such as betaine, beautiful another name for Sichuan Province flavine, physalin, make it have outstanding health-care efficacy.The essential nutriment that the fruit of Chinese wolfberry contains the healthy eye such as abundant carrotene, multivitamin and calcium, iron, therefore there is the merit of improving eyesight, is commonly called as " bright eye ".Ancient Chinese medicine doctor treatment deficiency of liver-blood, deficiency of kidney-YIN cause looks thing duskization and yctalopia, usually uses the fruit of Chinese wolfberry.Famous prescription " Qiju Dihuang Wan ", just take the fruit of Chinese wolfberry as main medicine.
The functional food that current China has liver protection effect is of less types, these functional food or compound product, or the not bright food of action component, although prove to have liver protection effect through human body or zoopery, but be still not clear and there is the active ingredient of this function or extremely content standard, detection method of the structure of function factor, can only carry out functional detection, and functional detection is subject to the impact of the factors such as time, funds.Following functional food for protecting liver: compound " Xiling " Medicinal granules is mainly mixed by rabdosia lophanthide, Black Ganoderma, gynostemma pentaphylla, Poria cocos, dried longan pulp, the fruit of Chinese wolfberry, mushroom, white fungus etc., newborn pigeon health spirits is take squab as main spice, be equipped with the Chinese herbal medicines such as the fruit of Chinese wolfberry, red date, raw lalang grass rhizome, through baking, three grades of immersions, filtrations, make, it is take loach enzymolysis protein as primary raw material that lucky star board liver protects capsule, although above-mentioned functions food has the function of protecting liver, lowering enzymes, but ubiquity complicated component, the shortcoming that active ingredient is not clear, can only belong to second generation functional food.And the clear and definite functional food of active ingredient structure and content, third generation functional food is less in the research and development of China, lags behind America and Europe and Japan.The exploitation of Zhe Shi China functional food also has very large gap compared with advanced international standard, is unfavorable for finding one's way into world market.
Summary of the invention
Technical problem to be solved by this invention is to provide that a kind of technique is simple, the preparation method of a kind of matrimony vine liver-protecting tablet of low production cost.
For solving above technical problem, the preparation method of a kind of matrimony vine liver-protecting tablet of the present invention, comprises the steps:
(1) anti-liver sheet masterbatch is granulated:
Get 15～40 parts of kudzu root extracts, 5～20 parts of glycyrrhizic acids, 20～35 parts of bee glue powders, 20～60 parts of matrimony vines, 1～10 part of low-substituted hydroxypropyl cellulose, 1～10 part of Ac-Di-Sol, 0.5～10 part of dolomol, pulverizes through pulverizer, obtains the mixing fine powders of various materials;
(2) coating agent masterbatch:
Get 5～20 parts of hydroxypropyl methylcelluloses, 20～30 parts of polyethylene glycol, 5～10 parts of talcum powder, 20～30 parts of titanium dioxides, 15～30 parts of iron oxide browns, 50～75 parts of maltitols;
(3) mix:
By step (1) gained mixing fine powders pour in mixer, stir 40～50 minutes, it is evenly distributed;
(4) compressing tablet:
The fine powder mixture of step (3) is inserted in tablet press machine and carried out compressing tablet, and controlling compressing tablet pressure is 0.2～0.5MPa, and monolithic is heavily 0.5～0.7g;
(5) dressing:
Get the masterbatch of step (2) and pour in pure water, stir, make suspendible coating solution, then utilize efficient atresia seed-coating machine to carry out film coating to the tablet of step (4) gained, make matrimony vine liver-protecting tablet finished product.
Preparation method's method of above-mentioned a kind of matrimony vine liver-protecting tablet, is characterized in that: the particle diameter of the mixing fine powders described in step (1) is between 60～90 orders.
Compared with prior art, the beneficial effect that the present invention has is:
The present invention is take matrimony vine as primary raw material; by adding partial supplementary material, make the health food that chemical damage is had to auxiliary protection function---matrimony vine liver-protecting tablet; can effectively prevent and treat fatty liver; after Patients with Fatty Liver is edible; what have is down to moderate from severe, and what have is down to slightly from moderate, therefore; this matrimony vine liver-protecting tablet improves liver function to human body and has obvious benefit, and market prospects are wide.
The specific embodiment
For ease of understanding the present invention, it is as follows that the present invention enumerates embodiment.Those skilled in the art should understand, described embodiment only, for helping to understand the present invention, should not be considered as concrete restriction of the present invention.
As no specific instructions, various raw material of the present invention all can obtain by commercially available; Or prepare according to the conventional method of this area.Unless otherwise defined or described herein, all specialties used herein are identical with the art technology meaning that skillfully person of entering is familiar with scientific words.In addition any method similar or impartial to described content and material all can be applicable in the inventive method.
Unless otherwise defined or described herein, the familiar meaning of all specialties used herein and scientific words and those skilled in the art is identical.In addition any method similar or impartial to described content and material all can be applicable in the inventive method.
Embodiment 1
(1) anti-liver sheet masterbatch is granulated:
Get 15～40 parts of kudzu root extracts, 5～20 parts of glycyrrhizic acids, 20～35 parts of bee glue powders, 20～60 parts of matrimony vines, 1～10 part of low-substituted hydroxypropyl cellulose, 1～10 part of Ac-Di-Sol, 0.5～10 part of dolomol, pulverizes through pulverizer, obtains the mixing fine powders of various materials;
(2) coating agent masterbatch:
Get 5～20 parts of hydroxypropyl methylcelluloses, 20～30 parts of polyethylene glycol, 5～10 parts of talcum powder, 20～30 parts of titanium dioxides, 15～30 parts of iron oxide browns, 50～75 parts of maltitols;
(3) mix:
By step (1) gained mixing fine powders pour in mixer, stir 40～50 minutes, it is evenly distributed;
(4) compressing tablet:
The fine powder mixture of step (3) is inserted in tablet press machine and carried out compressing tablet, and controlling compressing tablet pressure is 0.2～0.5MPa, and monolithic is heavily 0.5～0.7g;
(5) dressing:
Get the masterbatch of step (2) and pour in pure water, stir, make suspendible coating solution, then utilize efficient atresia seed-coating machine to carry out film coating to the tablet of step (4) gained, make matrimony vine liver-protecting tablet finished product.
The each ingredients weight parts of above-mentioned anti-liver sheet masterbatch is as follows:
The particle diameter of the mixing fine powders of above-mentioned steps (1) is between 60～90 orders.
Embodiment 2
(1) anti-liver sheet masterbatch is granulated:
Get 15～40 parts of kudzu root extracts, 5～20 parts of glycyrrhizic acids, 20～35 parts of bee glue powders, 20～60 parts of matrimony vines, 1～10 part of low-substituted hydroxypropyl cellulose, 1～10 part of Ac-Di-Sol, 0.5～10 part of dolomol, pulverizes through pulverizer, obtains the mixing fine powders of various materials;
(2) coating agent masterbatch:
Get 5～20 parts of hydroxypropyl methylcelluloses, 20～30 parts of polyethylene glycol, 5～10 parts of talcum powder, 20～30 parts of titanium dioxides, 15～30 parts of iron oxide browns, 50～75 parts of maltitols;
(3) mix:
By step (1) gained mixing fine powders pour in mixer, stir 40～50 minutes, it is evenly distributed;
(4) compressing tablet:
The fine powder mixture of step (3) is inserted in tablet press machine and carried out compressing tablet, and controlling compressing tablet pressure is 0.2～0.5MPa, and monolithic is heavily 0.5～0.7g;
(5) dressing:
Get the masterbatch of step (2) and pour in pure water, stir, make suspendible coating solution, then utilize efficient atresia seed-coating machine to carry out film coating to the tablet of step (4) gained, make matrimony vine liver-protecting tablet finished product.
The each ingredients weight parts of above-mentioned anti-liver sheet masterbatch is as follows:
The particle diameter of the mixing fine powders of above-mentioned steps (1) is between 60～90 orders.
Embodiment 3
(1) anti-liver sheet masterbatch is granulated:
Get 15～40 parts of kudzu root extracts, 5～20 parts of glycyrrhizic acids, 20～35 parts of bee glue powders, 20～60 parts of matrimony vines, 1～10 part of low-substituted hydroxypropyl cellulose, 1～10 part of Ac-Di-Sol, 0.5～10 part of dolomol, pulverizes through pulverizer, obtains the mixing fine powders of various materials;
(2) coating agent masterbatch:
Get 5～20 parts of hydroxypropyl methylcelluloses, 20～30 parts of polyethylene glycol, 5～10 parts of talcum powder, 20～30 parts of titanium dioxides, 15～30 parts of iron oxide browns, 50～75 parts of maltitols;
(3) mix:
By step (1) gained mixing fine powders pour in mixer, stir 40～50 minutes, it is evenly distributed;
(4) compressing tablet:
The fine powder mixture of step (3) is inserted in tablet press machine and carried out compressing tablet, and controlling compressing tablet pressure is 0.2～0.5MPa, and monolithic is heavily 0.5～0.7g;
(5) dressing:
Get the masterbatch of step (2) and pour in pure water, stir, make suspendible coating solution, then utilize efficient atresia seed-coating machine to carry out film coating to the tablet of step (4) gained, make matrimony vine liver-protecting tablet finished product.
The each ingredients weight parts of above-mentioned anti-liver sheet masterbatch is as follows:
The particle diameter of the mixing fine powders of above-mentioned steps (1) is between 60～90 orders.
Applicant's statement, person of ordinary skill in the field is on the basis of above-described embodiment, by the concrete content point value of above-described embodiment component, combined with the technical scheme of summary of the invention part, thereby the new number range producing, also be one of record scope of the present invention, the application, for making description simple and clear, is no longer enumerated these number ranges.
Claims (2)
1. a preparation method for matrimony vine liver-protecting tablet, is characterized in that comprising the steps:
(1) anti-liver sheet masterbatch is granulated:
Get 15～40 parts of kudzu root extracts, 5～20 parts of glycyrrhizic acids, 20～35 parts of bee glue powders, 20～60 parts of matrimony vines, 1～10 part of low-substituted hydroxypropyl cellulose, 1～10 part of Ac-Di-Sol, 0.5～10 part of dolomol, pulverizes through pulverizer, obtains the mixing fine powders of various materials;
(2) coating agent masterbatch:
Get 15 parts of hydroxypropyl methylcelluloses, 30 parts of polyethylene glycol, 10 parts of talcum powder, 25 parts of titanium dioxides, 25 parts of iron oxide browns, 60 parts of maltitols;
(3) mix:
By step (1) gained mixing fine powders pour in mixer, stir 40～50 minutes, it is evenly distributed;
(4) compressing tablet:
The fine powder mixture of step (3) is inserted in tablet press machine and carried out compressing tablet, and controlling compressing tablet pressure is 0.2～0.5MPa, and monolithic is heavily 0.5～0.7g;
(5) dressing:
Get the masterbatch of step (2) and pour in pure water, stir, make suspendible coating solution, then utilize efficient atresia seed-coating machine to carry out film coating to the tablet of step (4) gained, make matrimony vine liver-protecting tablet finished product.
2. preparation method's method of a kind of matrimony vine liver-protecting tablet as claimed in claim 1, is characterized in that: the particle diameter of the mixing fine powders described in step (1) is between 60～90 orders.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310572437.8A CN103750291A (en) | 2013-11-13 | 2013-11-13 | Preparation method of Chinese wolfberry tablet for liver protection |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310572437.8A CN103750291A (en) | 2013-11-13 | 2013-11-13 | Preparation method of Chinese wolfberry tablet for liver protection |
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| CN103750291A true CN103750291A (en) | 2014-04-30 |
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| CN201310572437.8A Pending CN103750291A (en) | 2013-11-13 | 2013-11-13 | Preparation method of Chinese wolfberry tablet for liver protection |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105410569A (en) * | 2015-12-08 | 2016-03-23 | 广东省农业科学院蚕业与农产品加工研究所 | Preparation method of mulberry drink with protective effect on alcoholic liver injury |
| CN105707397A (en) * | 2016-04-15 | 2016-06-29 | 济南银中容和堂药业有限公司 | Heathy vitamin candy |
| CN108925976A (en) * | 2017-05-24 | 2018-12-04 | 重庆戴贺李生物科技有限公司 | A kind of coating and preparation method for keeping lycium ruthenicum piece anthocyanidin bioactivity stable |
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| CN101744865A (en) * | 2008-12-18 | 2010-06-23 | 山东福田药业有限公司 | Preparation method of xylitol liver-protecting tablet |
| CN102578671A (en) * | 2012-03-20 | 2012-07-18 | 牟一心 | Alcoholism-relieving liver-protecting botanical nutritional beverage and making method thereof |
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2013
- 2013-11-13 CN CN201310572437.8A patent/CN103750291A/en active Pending
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| CN101223988A (en) * | 2008-02-03 | 2008-07-23 | 王东桥 | Healthy drink for anti-alcoholic, protecting liver, invigorating the spleen and nourishing stomach and preparing method thereof |
| CN101744865A (en) * | 2008-12-18 | 2010-06-23 | 山东福田药业有限公司 | Preparation method of xylitol liver-protecting tablet |
| CN102578671A (en) * | 2012-03-20 | 2012-07-18 | 牟一心 | Alcoholism-relieving liver-protecting botanical nutritional beverage and making method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105410569A (en) * | 2015-12-08 | 2016-03-23 | 广东省农业科学院蚕业与农产品加工研究所 | Preparation method of mulberry drink with protective effect on alcoholic liver injury |
| CN105410569B (en) * | 2015-12-08 | 2018-07-24 | 广东省农业科学院蚕业与农产品加工研究所 | A kind of preparation method to mulberry beverage of the alcoholic liver injury with protective effect |
| CN105707397A (en) * | 2016-04-15 | 2016-06-29 | 济南银中容和堂药业有限公司 | Heathy vitamin candy |
| CN108925976A (en) * | 2017-05-24 | 2018-12-04 | 重庆戴贺李生物科技有限公司 | A kind of coating and preparation method for keeping lycium ruthenicum piece anthocyanidin bioactivity stable |
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Application publication date: 20140430 |