CN104055935B - It is a kind of to cooperate with the Chinese medicine composition for improving immunity - Google Patents
It is a kind of to cooperate with the Chinese medicine composition for improving immunity Download PDFInfo
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- CN104055935B CN104055935B CN201410324415.4A CN201410324415A CN104055935B CN 104055935 B CN104055935 B CN 104055935B CN 201410324415 A CN201410324415 A CN 201410324415A CN 104055935 B CN104055935 B CN 104055935B
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Abstract
The present invention relates to the Chinese medicine composition that a kind of collaboration improves immunity, the composition of technical solution of the present invention is using Radix Codonopsis, the Radix Astragali, ganoderma lucidum, the fruit of Chinese wolfberry and jujube as main active.The Chinese medicine composition have effects that strengthen body immunity, it is evident in efficacy, action temperature and.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition that there is collaboration to improve body immunity.
Technical background
With the continuous social and economic development, the increasingly raising of people's living standard, people to health degree of concern by
It is cumulative to add.We receive many outside threats, including air pollution, environmental pollution, operating pressure, economy at everyone health
Pressure, bacterial virus, improper diet etc..Furthermore, due to city work, the change of rhythm of life, it is easy to make one to produce slowly
Fatigue, i.e. sub-health state, all these unfavorable healthy factors, it will usually make us it is spiritual can not concentrate, memory loss,
Often indolent and listless, aging ahead of time.Therefore autoimmunity is improved, the ability of the various unfavorable health factors of enhancing confrontation is most important.
The health products species for being used to strengthen immunity of organisms at present on the market is various, but action effect is uneven.
The content of the invention
Strengthen the Chinese medicine composition of immunity of organisms it is an object of the invention to provide a kind of.By with Radix Codonopsis, the Radix Astragali, spirit
Sesame, the fruit of Chinese wolfberry and jujube are main Chinese medicine, by mutual synergistic function, to strengthen immune effect.
In order to solve the above technical problems, the present invention provides a kind of health products that there is collaboration to improve body immunity combination
Thing, raw material of the said composition comprising following weight parts is constituted：Radix Codonopsis, the Radix Astragali, ganoderma lucidum, the fruit of Chinese wolfberry and jujube, the weight of each component
Number is followed successively by 1~65 part, 1~65 part, 1~60 part, 1~70 part and 1~65 part；It is preferred that in described composition：Radix Codonopsis, Huang
Stilbene, ganoderma lucidum, the parts by weight of the fruit of Chinese wolfberry and jujube are followed successively by 1~40 part, 1~40 part, 1~20 part, 1~45 part and 1~40 part；
Further preferably in described composition：Radix Codonopsis, the Radix Astragali, ganoderma lucidum, the parts by weight of the fruit of Chinese wolfberry and jujube be followed successively by 1~10 part, 1
~10 parts, 1~5 part, 1~15 part and 1~10 part.In most preferably described composition：
Radix Codonopsis, the Radix Astragali, ganoderma lucidum, the parts by weight of the fruit of Chinese wolfberry and jujube be followed successively by 2~5 parts, 2~5 parts, 1~3 part, 5~10
Part and 2~5 parts.
Radix Codonopsis described in technical solution of the present invention is Campanulaceae Radix Codonopsis, codonopsis pilosula var. modesta, radix codonpsis tangshen, pipe flower Radix Codonopsis, ball
The root of flower Radix Codonopsis, emblem hair Radix Codonopsis.Described Radix Codonopsis includes Radix Codonopsis essence after Radix Codonopsis extract, ground crushing after processing is refined
Various forms in powder either Radix Codonopsis growth course.
The Radix Astragali described in technical solution of the present invention is a kind of Papillionoideae, the plant of Astragalus, and the described Radix Astragali is included
Various forms after processing is refined after Astragalus Root P.E, ground crushing in Radix Astragali fine powder either Radix Astragali growth course.
Ganoderma lucidum described in technical solution of the present invention is a kind of Polyporaceae category, the plant of Ganoderma, and described ganoderma lucidum includes
Various forms after processing is refined after Ganodenna Lucidum P.E, ground crushing in ganoderma lucidum essence powder either ganoderma lucidum growth course.
The fruit of Chinese wolfberry described in technical solution of the present invention is the ripening fruits of matrimony vine of solanaceae plant or lycium barbarum, described Chinese holly
Qi includes various in medlar fine powder either matrimony vine growth course after wolfberry fruit extract, ground crushing after processing is refined
Form.
Jujube described in technical solution of the present invention is Rhamnaceae, the ripening fruits of zizyphus, and described jujube is included by adding
Various forms after work is refined after Fructus Jujubae extract, ground crushing in jujube fine powder either jujube growth course.
Composition described in technical solution of the present invention, which is used to prepare to have, to be improved in immunity health medicine.
The composition of the present invention, can directly pulverize or by this area conventional extraction techniques such as water extraction and alcohol precipitation method or
The Hydrolysis kinetics of ethanol extract from water precipitation as the composition for the treatment of active component.The active component can with it is pharmaceutically acceptable
Carrier or excipient composition various pharmaceutical formulations are made, be such as in how granular tablet, granule, capsule, or oral liquid etc..
According to needs are used, composition of the invention can also be processed into sustained release preparation or quick releasing formulation.Wherein described pharmacy can connect
The carrier or excipient received are selected according to different formulations.These carriers used or excipient are for the common of pharmaceutical field
Technical staff may decide that.
The preparation method of oral liquid, can with but be not only limited to following one kind, after such as active principle is mixed, add water pan-fried
Boil, decoction liquor is filtered, obtain solution, resulting solution is concentrated to give medicinal extract, then gained medicinal extract is dissolved in medicinal extract weight 5-10
The concentration of times weight is in the ethanol water according to weight meter 95%, stirring mixing, quantitative separating obtains oral liquid formulations.
The preparation method of tablet is that active principle mixture sieves, and is crushed, fully in the auxiliary agent conventional with preparing tablet
After well mixed, 40-80 eye mesh screens are crossed, it is by tabletting that the direct machine of dry powder is tabletted.
The preparation technology of capsule preparations can be that active principle mixture sieves, in the auxiliary agent conventional with preparing tablet
Crush, be sufficiently mixed it is uniform after, cross 40-80 eye mesh screens, by granulation, dry, fill capsule after the process such as whole grain, polish, packaging, i.e.,
Obtain finished product.
The definition of " collaboration is improved " can be understood as after several medicinal material combinations in the present invention, and its drug effect is relative to exclusive use
When raising；Drug effect is more lasting；Composition produces unexpected effect in new preventing and treating or healthcare field.Inventor passes through
Experiment finds that composition of the invention has effects that to improve body immunity, and these single doses pass through a certain proportion of composition
Afterwards to human body act on beneficial effect be single dose it is incomparable.
Beneficial effects of the present invention：
Pharmaceutical composition of the present invention has invigorating qi for consolidating superficies, improves immunity of organisms effect, and medicine of the present invention is not not warm dry, tool
Have strengthen immunity, it is evident in efficacy, action temperature and, have no toxic side effect.The simple production process of the medicine, be easy to take, curative effect
Significantly, it is a kind of preferable medicine for improving human immunity.
Embodiment：
With reference to embodiment, the invention will be further described, but the Protection Code scope not limited to this of the present invention：
Embodiment 1：
Radix Codonopsis 10g, 5g Radix Astragali, 3g ganoderma lucidums, the 8g fruits of Chinese wolfberry and 8g jujubes
The component described in embodiment 1 is weighed, following methods are respectively adopted and prepare capsule preparations.The system of capsule preparations
Preparation Method：Component is soaked 40 minutes, the water surface is higher than raw material, it is 8 times of total dose to add water inventory, and small fire is boiled after boiling
State, maintains liquid level higher than raw material Chinese medicine height, decocts 2 hours, filter to take filtrate, add 6 times of water of total dose, small after boiling
Fire boiling state, maintains liquid level higher than raw material Chinese medicine height, decocts 2 hours, filtering merges filtrate twice, through (the pressure that is concentrated under reduced pressure
0.06MPa, 65 DEG C of temperature) to dry cream, crush, through 300 mesh sieves, add the magnesium stearate of gross weight 2%, load capsule.
Embodiment 2：
Radix Codonopsis 1g, 10g Radix Astragali, 1g ganoderma lucidums, the 15g fruits of Chinese wolfberry and 10g jujubes
Weigh the Chinese medicine of embodiment 2 and be dried and crushed into coarse powder, carried by solvent of 50-60% ethanol in 60-70 DEG C of backflow
Take, extract solution is after ethanol of going out, and low temperature is condensed into thick medicinal extract, dry, pulverize into fine powder, sieve, mix, granulation is pressed into
Tablet.
Embodiment 3：
Radix Codonopsis 5g, 1g Radix Astragali, 5g ganoderma lucidums, the 1g fruits of Chinese wolfberry and 1g jujubes
Weigh the Chinese medicine of embodiment 3 and be dried and crushed into fine powder, sieve, mix, load hard by softgel shell, be made in the present invention
Drug composition.
Embodiment 4：
Radix Codonopsis 2g, 5g Radix Astragali, 3g ganoderma lucidums, the 10g fruits of Chinese wolfberry and 5g jujubes
Each component in embodiment 4 is weighed, after said components are mixed, adds water to cook, decoction liquor is filtered, obtain solution,
Resulting solution is concentrated to give medicinal extract, the concentration that then gained medicinal extract is dissolved in 5-10 times of weight of medicinal extract weight is according to weight meter
In 95% ethanol water, stirring mixing, quantitative separating obtains oral liquid formulations.
Embodiment 5：
Radix Codonopsis 5g, 2g Radix Astragali, 1g ganoderma lucidums, the 5g fruits of Chinese wolfberry and 2g jujubes
Each component in embodiment 5 is weighed, above-mentioned Chinese medicine is dried and crushed into fine powder, is sieved, is mixed, loads hard by capsule
Shell, is made the Chinese medicine composition of the present invention.
Test example 1：The present invention is to improving the clinical efficacy of immune function of human body
1st, patient：Elderly patients, suffer from a variety of chronic diseases.
2nd, method of administration and the course for the treatment of：
The oral embodiment of the present invention 1, embodiment 2, embodiment 3, embodiment 4, embodiment 5；Control：Radix Codonopsis；The Radix Astragali；Spirit
Sesame；Radix Codonopsis+the Radix Astragali+the fruit of Chinese wolfberry+jujube (1：1：1：1)；Ganoderma lucidum+the fruit of Chinese wolfberry+Radix Astragali (1：1：1)；The fruit of Chinese wolfberry+jujube (1：1)
Adult：Each 5g, 3 times a day.
Above patient is with one month for a course for the treatment of, and it treats the 1-3 course for the treatment of.
3rd, observational technique：
Enter promoting circulation of blood, urine, feces routine test and the heart, pulmonary function test, and observe：Heating, aversion to cold, sniffle, pharyngeal disease
Shape and systemic conditions and temperature of having a medical check-up, pharyngeal tonsils, the change such as tongue picture pulse condition carry out therapeutic evaluation respectively.
4th, therapeutic evaluation
The prescription of the present invention of table 1 improves the clinical observation of immune function of human body
| Composition | Number of cases | It is obviously improved | Improve | It is invalid | Total improvement rate % |
| Embodiment 1 | 132 | 101 | 15 | 16 | 87.9 |
| Embodiment 2 | 145 | 113 | 12 | 20 | 86.2 |
| Embodiment 3 | 119 | 94 | 13 | 12 | 89.9 |
| Embodiment 4 | 136 | 110 | 12 | 14 | 89.7 |
| Embodiment 5 | 151 | 118 | 13 | 20 | 86.8 |
| Radix Codonopsis | 39 | 5 | 15 | 19 | 51.3 |
| The Radix Astragali | 45 | 6 | 19 | 20 | 55.6 |
| Ganoderma lucidum | 79 | 10 | 34 | 35 | 55.7 |
| Radix Codonopsis+the Radix Astragali+the fruit of Chinese wolfberry+jujube | 68 | 22 | 28 | 18 | 73.5 |
| Ganoderma lucidum+the fruit of Chinese wolfberry+Radix Astragali | 83 | 30 | 29 | 24 | 71.1 |
| The fruit of Chinese wolfberry+jujube | 61 | 16 | 25 | 20 | 67.2 |
From table 1 it follows that the composition of technical solution of the present invention has effects that to improve body immunity, these lists
Agent by after a certain proportion of composition to human body act on beneficial effect be single dose it is incomparable.
Claims (5)
1. a kind of Chinese medicine composition for improving immunity, it is characterised in that：Said composition is made up of the raw material of following weight parts：Party
Ginseng, the Radix Astragali, ganoderma lucidum, the fruit of Chinese wolfberry and jujube, the parts by weight of each component be followed successively by 1 ~ 40 part, 1 ~ 40 part, 1 ~ 20 part, 1 ~ 45 part and
1 ~ 40 part.
2. the Chinese medicine composition according to claim 1 for improving immunity, it is characterised in that：Radix Codonopsis, the Radix Astragali, ganoderma lucidum, Chinese holly
The parts by weight of matrimony vine and jujube are followed successively by 1 ~ 10 part, 1 ~ 10 part, 1 ~ 5 part, 1 ~ 15 part and 1 ~ 10 part.
3. the Chinese medicine composition according to claim 2 for improving immunity, it is characterised in that：Radix Codonopsis, the Radix Astragali, ganoderma lucidum, Chinese holly
The parts by weight of matrimony vine and jujube are followed successively by 2 ~ 5 parts, 2 ~ 5 parts, 1 ~ 3 part, 5 ~ 10 parts and 2 ~ 5 parts.
4. the Chinese medicine composition of the raising immunity according to claim any one of 1-3, it is characterised in that：Described combination
Thing is the preparation of peroral dosage form.
5. the composition described in claim any one of 1-3 is being prepared with the purposes in improving immunity health medicine.
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105851387A (en) * | 2016-05-04 | 2016-08-17 | 叶阿彬 | Preparation process of compound lucid ganoderma and red date tea |
| WO2019024013A1 (en) * | 2017-08-02 | 2019-02-07 | 江苏安惠生物科技有限公司 | Liver-protecting healthcare capsule for enhanced immunity |
| CN108567854A (en) * | 2017-10-11 | 2018-09-25 | 山西中医药大学 | Join Ling oral liquid and preparation method thereof |
| CN113455567A (en) * | 2021-06-25 | 2021-10-01 | 山西振东五和健康科技股份有限公司 | Lucid ganoderma, ginseng and astragalus root tea substitute and preparation method thereof |
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| CN101455391A (en) * | 2008-11-27 | 2009-06-17 | 成都润馨堂药业有限公司 | Nutrient health-care food capable of immunomodulating and preparation method thereof |
| CN103656121A (en) * | 2013-12-06 | 2014-03-26 | 山东中大药业有限公司 | Immunity-improving traditional Chinese medicine composition and preparation method thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101455391A (en) * | 2008-11-27 | 2009-06-17 | 成都润馨堂药业有限公司 | Nutrient health-care food capable of immunomodulating and preparation method thereof |
| CN103656121A (en) * | 2013-12-06 | 2014-03-26 | 山东中大药业有限公司 | Immunity-improving traditional Chinese medicine composition and preparation method thereof |
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| 中药增强免疫剂最新研究成果发布;胡元亮;《北方牧业》;20091030;第30页左栏第1，4,5段 * |
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