CN103747814B - 减压治疗与清创系统以及方法 - Google Patents
减压治疗与清创系统以及方法 Download PDFInfo
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- CN103747814B CN103747814B CN201280040371.1A CN201280040371A CN103747814B CN 103747814 B CN103747814 B CN 103747814B CN 201280040371 A CN201280040371 A CN 201280040371A CN 103747814 B CN103747814 B CN 103747814B
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- A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
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- A—HUMAN NECESSITIES
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- A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
- Y10T137/0402—Cleaning, repairing, or assembling
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
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- Veterinary Medicine (AREA)
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- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Materials For Medical Uses (AREA)
- Surgical Instruments (AREA)
- External Artificial Organs (AREA)
Priority Applications (1)
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CN201711227173.7A CN107854737B (zh) | 2011-08-31 | 2012-08-17 | 减压治疗与清创系统以及方法 |
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US201161529510P | 2011-08-31 | 2011-08-31 | |
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PCT/US2012/051410 WO2013032745A1 (en) | 2011-08-31 | 2012-08-17 | Reduced-pressure treatment and debridement systems and methods |
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CN201711227173.7A Division CN107854737B (zh) | 2011-08-31 | 2012-08-17 | 减压治疗与清创系统以及方法 |
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CN103747814A CN103747814A (zh) | 2014-04-23 |
CN103747814B true CN103747814B (zh) | 2017-11-28 |
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JP (2) | JP5967675B2 (ja) |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103702646B (zh) * | 2011-06-24 | 2016-03-30 | 凯希特许有限公司 | 采用组织固定元件的减压敷件 |
EP2750729B1 (en) | 2011-08-31 | 2015-05-27 | KCI Licensing, Inc. | Reduced-pressure treatment and debridement systems and methods |
US10342891B2 (en) * | 2013-09-19 | 2019-07-09 | Medline Industries, Inc. | Wound dressing containing saccharide and collagen |
WO2015116823A1 (en) * | 2014-01-29 | 2015-08-06 | The Johns Hopkins University | System and method for wound imaging and debridement |
CN103876890B (zh) * | 2014-03-25 | 2016-05-25 | 深圳市博立生物材料有限公司 | 一种湿性敷料 |
CN111839658B (zh) * | 2014-05-09 | 2024-07-16 | 3M创新知识产权公司 | 用于与负压和流体滴注一起使用的破坏性敷件 |
US10898217B2 (en) | 2014-05-09 | 2021-01-26 | Kci Licensing, Inc. | Dressing providing apertures with multiple orifice sizes for negative-pressure therapy |
CN106456848B (zh) * | 2014-05-09 | 2020-03-06 | 凯希特许有限公司 | 与负压和流体滴注一起使用的清创敷件 |
USD832999S1 (en) * | 2015-05-05 | 2018-11-06 | Medaxis Ag | Pump for debridement by water jet |
CN105213107A (zh) * | 2015-08-24 | 2016-01-06 | 泰州市榕兴医疗用品股份有限公司 | 一种菠萝酶凝胶敷料 |
AU2016385411B2 (en) * | 2016-01-06 | 2021-10-14 | Solventum Intellectual Properties Company | System and methods for the treatment of wounds with dressing having closed cells |
JP7288901B2 (ja) * | 2017-10-24 | 2023-06-08 | スリーエム イノベイティブ プロパティズ カンパニー | 創傷清拭用の創傷包帯及びこれを使用したシステム |
JP2022518043A (ja) * | 2019-01-24 | 2022-03-11 | ケーシーアイ ライセンシング インコーポレイテッド | 可変密度のドレッシング |
DE102020212711A1 (de) | 2020-10-08 | 2022-04-14 | Fasciotens Gmbh | Durchführungselement zur abgedichteten Durchführung eines Fadens durch eine Folie zur Verwendung bei einer Unterdruck-Wundtherapie sowie Folie zur Anwendung bei einer Unterdruck-Wundtherapie |
CN115475049A (zh) * | 2022-09-23 | 2022-12-16 | 长沙海润生物技术有限公司 | 一种负压引流联合ph检测清创敷料及其应用方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101257875A (zh) * | 2005-09-06 | 2008-09-03 | 泰科保健集团有限合伙公司 | 具有微型泵的独立伤口敷料 |
CN102089017A (zh) * | 2008-05-30 | 2011-06-08 | 凯希特许有限公司 | 透明减压敷料和系统 |
Family Cites Families (149)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1355846A (en) | 1920-02-06 | 1920-10-19 | David A Rannells | Medical appliance |
US2547758A (en) | 1949-01-05 | 1951-04-03 | Wilmer B Keeling | Instrument for treating the male urethra |
US2632443A (en) | 1949-04-18 | 1953-03-24 | Eleanor P Lesher | Surgical dressing |
GB692578A (en) | 1949-09-13 | 1953-06-10 | Minnesota Mining & Mfg | Improvements in or relating to drape sheets for surgical use |
US2682873A (en) | 1952-07-30 | 1954-07-06 | Johnson & Johnson | General purpose protective dressing |
NL189176B (nl) | 1956-07-13 | 1900-01-01 | Hisamitsu Pharmaceutical Co | Pleister op basis van een synthetische rubber. |
US2969057A (en) | 1957-11-04 | 1961-01-24 | Brady Co W H | Nematodic swab |
US3066672A (en) | 1960-09-27 | 1962-12-04 | Jr William H Crosby | Method and apparatus for serial sampling of intestinal juice |
US3367332A (en) | 1965-08-27 | 1968-02-06 | Gen Electric | Product and process for establishing a sterile area of skin |
US3520300A (en) | 1967-03-15 | 1970-07-14 | Amp Inc | Surgical sponge and suction device |
US3568675A (en) | 1968-08-30 | 1971-03-09 | Clyde B Harvey | Fistula and penetrating wound dressing |
US3682180A (en) | 1970-06-08 | 1972-08-08 | Coilform Co Inc | Drain clip for surgical drain |
BE789293Q (fr) | 1970-12-07 | 1973-01-15 | Parke Davis & Co | Pansement medico-chirugical pour brulures et lesions analogues |
US3826254A (en) | 1973-02-26 | 1974-07-30 | Verco Ind | Needle or catheter retaining appliance |
DE2527706A1 (de) | 1975-06-21 | 1976-12-30 | Hanfried Dr Med Weigand | Einrichtung zum einleiten von kontrastmittel in einen kuenstlichen darmausgang |
DE2640413C3 (de) | 1976-09-08 | 1980-03-27 | Richard Wolf Gmbh, 7134 Knittlingen | Katheter-Überwachungsgerät |
NL7710909A (nl) | 1976-10-08 | 1978-04-11 | Smith & Nephew | Samengestelde hechtstrook. |
GB1562244A (en) | 1976-11-11 | 1980-03-05 | Lock P M | Wound dressing materials |
US4080970A (en) | 1976-11-17 | 1978-03-28 | Miller Thomas J | Post-operative combination dressing and internal drain tube with external shield and tube connector |
US4139004A (en) | 1977-02-17 | 1979-02-13 | Gonzalez Jr Harry | Bandage apparatus for treating burns |
US4184510A (en) | 1977-03-15 | 1980-01-22 | Fibra-Sonics, Inc. | Valued device for controlling vacuum in surgery |
US4165748A (en) | 1977-11-07 | 1979-08-28 | Johnson Melissa C | Catheter tube holder |
US4245637A (en) | 1978-07-10 | 1981-01-20 | Nichols Robert L | Shutoff valve sleeve |
SE414994B (sv) | 1978-11-28 | 1980-09-01 | Landstingens Inkopscentral | Venkateterforband |
US4382441A (en) | 1978-12-06 | 1983-05-10 | Svedman Paul | Device for treating tissues, for example skin |
US4266545A (en) | 1979-04-06 | 1981-05-12 | Moss James P | Portable suction device for collecting fluids from a closed wound |
US4284079A (en) | 1979-06-28 | 1981-08-18 | Adair Edwin Lloyd | Method for applying a male incontinence device |
US4261363A (en) | 1979-11-09 | 1981-04-14 | C. R. Bard, Inc. | Retention clips for body fluid drains |
US4569348A (en) | 1980-02-22 | 1986-02-11 | Velcro Usa Inc. | Catheter tube holder strap |
EP0035583B1 (de) | 1980-03-11 | 1985-08-14 | Schmid, Eduard, Dr.Dr.med. | Hauttransplantations-Druckverband |
US4297995A (en) | 1980-06-03 | 1981-11-03 | Key Pharmaceuticals, Inc. | Bandage containing attachment post |
US4333468A (en) | 1980-08-18 | 1982-06-08 | Geist Robert W | Mesentery tube holder apparatus |
US4465485A (en) | 1981-03-06 | 1984-08-14 | Becton, Dickinson And Company | Suction canister with unitary shut-off valve and filter features |
US4392853A (en) | 1981-03-16 | 1983-07-12 | Rudolph Muto | Sterile assembly for protecting and fastening an indwelling device |
US4373519A (en) | 1981-06-26 | 1983-02-15 | Minnesota Mining And Manufacturing Company | Composite wound dressing |
US4392858A (en) | 1981-07-16 | 1983-07-12 | Sherwood Medical Company | Wound drainage device |
US4419097A (en) | 1981-07-31 | 1983-12-06 | Rexar Industries, Inc. | Attachment for catheter tube |
AU550575B2 (en) | 1981-08-07 | 1986-03-27 | Richard Christian Wright | Wound drainage device |
SE429197B (sv) | 1981-10-14 | 1983-08-22 | Frese Nielsen | Anordning for behandling av sar |
DE3146266A1 (de) | 1981-11-21 | 1983-06-01 | B. Braun Melsungen Ag, 3508 Melsungen | Kombinierte vorrichtung fuer eine medizinische saugdrainage |
US4551139A (en) | 1982-02-08 | 1985-11-05 | Marion Laboratories, Inc. | Method and apparatus for burn wound treatment |
US4475909A (en) | 1982-05-06 | 1984-10-09 | Eisenberg Melvin I | Male urinary device and method for applying the device |
EP0100148B1 (en) | 1982-07-06 | 1986-01-08 | Dow Corning Limited | Medical-surgical dressing and a process for the production thereof |
NZ206837A (en) | 1983-01-27 | 1986-08-08 | Johnson & Johnson Prod Inc | Thin film adhesive dressing:backing material in three sections |
US4548202A (en) | 1983-06-20 | 1985-10-22 | Ethicon, Inc. | Mesh tissue fasteners |
US4540412A (en) | 1983-07-14 | 1985-09-10 | The Kendall Company | Device for moist heat therapy |
US4543100A (en) | 1983-11-01 | 1985-09-24 | Brodsky Stuart A | Catheter and drain tube retainer |
US4525374A (en) | 1984-02-27 | 1985-06-25 | Manresa, Inc. | Treating hydrophobic filters to render them hydrophilic |
GB2157958A (en) | 1984-05-03 | 1985-11-06 | Ernest Edward Austen Bedding | Ball game net support |
US4897081A (en) | 1984-05-25 | 1990-01-30 | Thermedics Inc. | Percutaneous access device |
US5215522A (en) | 1984-07-23 | 1993-06-01 | Ballard Medical Products | Single use medical aspirating device and method |
GB8419745D0 (en) | 1984-08-02 | 1984-09-05 | Smith & Nephew Ass | Wound dressing |
US4872450A (en) | 1984-08-17 | 1989-10-10 | Austad Eric D | Wound dressing and method of forming same |
US4655754A (en) | 1984-11-09 | 1987-04-07 | Stryker Corporation | Vacuum wound drainage system and lipids baffle therefor |
US4826494A (en) | 1984-11-09 | 1989-05-02 | Stryker Corporation | Vacuum wound drainage system |
US4605399A (en) | 1984-12-04 | 1986-08-12 | Complex, Inc. | Transdermal infusion device |
US5037397A (en) | 1985-05-03 | 1991-08-06 | Medical Distributors, Inc. | Universal clamp |
US4640688A (en) | 1985-08-23 | 1987-02-03 | Mentor Corporation | Urine collection catheter |
US4710165A (en) | 1985-09-16 | 1987-12-01 | Mcneil Charles B | Wearable, variable rate suction/collection device |
US4758220A (en) | 1985-09-26 | 1988-07-19 | Alcon Laboratories, Inc. | Surgical cassette proximity sensing and latching apparatus |
US4733659A (en) | 1986-01-17 | 1988-03-29 | Seton Company | Foam bandage |
EP0256060A1 (en) | 1986-01-31 | 1988-02-24 | OSMOND, Roger L. W. | Suction system for wound and gastro-intestinal drainage |
US4838883A (en) | 1986-03-07 | 1989-06-13 | Nissho Corporation | Urine-collecting device |
JPS62281965A (ja) | 1986-05-29 | 1987-12-07 | テルモ株式会社 | カテ−テルおよびカテ−テル用固定部材 |
GB8621884D0 (en) | 1986-09-11 | 1986-10-15 | Bard Ltd | Catheter applicator |
GB2195255B (en) | 1986-09-30 | 1991-05-01 | Vacutec Uk Limited | Apparatus for vacuum treatment of an epidermal surface |
US4743232A (en) | 1986-10-06 | 1988-05-10 | The Clinipad Corporation | Package assembly for plastic film bandage |
DE3634569A1 (de) | 1986-10-10 | 1988-04-21 | Sachse Hans E | Kondomkatheter, ein harnroehrenkatheter zur verhinderung von aufsteigenden infektionen |
JPS63135179A (ja) | 1986-11-26 | 1988-06-07 | 立花 俊郎 | 薬物の経皮投与具 |
GB8628564D0 (en) | 1986-11-28 | 1987-01-07 | Smiths Industries Plc | Anti-foaming agent suction apparatus |
GB8706116D0 (en) | 1987-03-14 | 1987-04-15 | Smith & Nephew Ass | Adhesive dressings |
US4787888A (en) | 1987-06-01 | 1988-11-29 | University Of Connecticut | Disposable piezoelectric polymer bandage for percutaneous delivery of drugs and method for such percutaneous delivery (a) |
US4863449A (en) | 1987-07-06 | 1989-09-05 | Hollister Incorporated | Adhesive-lined elastic condom cathether |
US5176663A (en) | 1987-12-02 | 1993-01-05 | Pal Svedman | Dressing having pad with compressibility limiting elements |
US4906240A (en) | 1988-02-01 | 1990-03-06 | Matrix Medica, Inc. | Adhesive-faced porous absorbent sheet and method of making same |
US4985019A (en) | 1988-03-11 | 1991-01-15 | Michelson Gary K | X-ray marker |
GB8812803D0 (en) | 1988-05-28 | 1988-06-29 | Smiths Industries Plc | Medico-surgical containers |
US4919654A (en) | 1988-08-03 | 1990-04-24 | Kalt Medical Corporation | IV clamp with membrane |
US5000741A (en) | 1988-08-22 | 1991-03-19 | Kalt Medical Corporation | Transparent tracheostomy tube dressing |
EP0379416B1 (fr) | 1989-01-16 | 1995-03-08 | Roussel-Uclaf | Dérivés d'azabicycloheptène et leurs sels, leur procédé de préparation, leur application comme médicaments et les compositions les renfermant |
GB8906100D0 (en) | 1989-03-16 | 1989-04-26 | Smith & Nephew | Laminates |
US5100396A (en) | 1989-04-03 | 1992-03-31 | Zamierowski David S | Fluidic connection system and method |
US5527293A (en) | 1989-04-03 | 1996-06-18 | Kinetic Concepts, Inc. | Fastening system and method |
US4969880A (en) | 1989-04-03 | 1990-11-13 | Zamierowski David S | Wound dressing and treatment method |
US5261893A (en) | 1989-04-03 | 1993-11-16 | Zamierowski David S | Fastening system and method |
US5358494A (en) | 1989-07-11 | 1994-10-25 | Svedman Paul | Irrigation dressing |
JP2719671B2 (ja) | 1989-07-11 | 1998-02-25 | 日本ゼオン株式会社 | 創傷被覆材 |
US5232453A (en) | 1989-07-14 | 1993-08-03 | E. R. Squibb & Sons, Inc. | Catheter holder |
GB2235877A (en) | 1989-09-18 | 1991-03-20 | Antonio Talluri | Closed wound suction apparatus |
US5134994A (en) | 1990-02-12 | 1992-08-04 | Say Sam L | Field aspirator in a soft pack with externally mounted container |
US5092858A (en) | 1990-03-20 | 1992-03-03 | Becton, Dickinson And Company | Liquid gelling agent distributor device |
JP2941918B2 (ja) | 1990-09-19 | 1999-08-30 | テルモ株式会社 | 秤量装置 |
US5149331A (en) | 1991-05-03 | 1992-09-22 | Ariel Ferdman | Method and device for wound closure |
US5278100A (en) | 1991-11-08 | 1994-01-11 | Micron Technology, Inc. | Chemical vapor deposition technique for depositing titanium silicide on semiconductor wafers |
US5636643A (en) | 1991-11-14 | 1997-06-10 | Wake Forest University | Wound treatment employing reduced pressure |
US5645081A (en) | 1991-11-14 | 1997-07-08 | Wake Forest University | Method of treating tissue damage and apparatus for same |
US5279550A (en) | 1991-12-19 | 1994-01-18 | Gish Biomedical, Inc. | Orthopedic autotransfusion system |
US5167613A (en) | 1992-03-23 | 1992-12-01 | The Kendall Company | Composite vented wound dressing |
FR2690617B1 (fr) | 1992-04-29 | 1994-06-24 | Cbh Textile | Pansement adhesif transparent. |
DE4306478A1 (de) | 1993-03-02 | 1994-09-08 | Wolfgang Dr Wagner | Drainagevorrichtung, insbesondere Pleuradrainagevorrichtung, und Drainageverfahren |
US6241747B1 (en) | 1993-05-03 | 2001-06-05 | Quill Medical, Inc. | Barbed Bodily tissue connector |
US5342376A (en) | 1993-05-03 | 1994-08-30 | Dermagraphics, Inc. | Inserting device for a barbed tissue connector |
US5344415A (en) | 1993-06-15 | 1994-09-06 | Deroyal Industries, Inc. | Sterile system for dressing vascular access site |
US5437651A (en) | 1993-09-01 | 1995-08-01 | Research Medical, Inc. | Medical suction apparatus |
US5549584A (en) | 1994-02-14 | 1996-08-27 | The Kendall Company | Apparatus for removing fluid from a wound |
US5556375A (en) | 1994-06-16 | 1996-09-17 | Hercules Incorporated | Wound dressing having a fenestrated base layer |
US5607388A (en) | 1994-06-16 | 1997-03-04 | Hercules Incorporated | Multi-purpose wound dressing |
US5664270A (en) | 1994-07-19 | 1997-09-09 | Kinetic Concepts, Inc. | Patient interface system |
WO1996005873A1 (en) | 1994-08-22 | 1996-02-29 | Kinetic Concepts Inc. | Wound drainage equipment |
DE29504378U1 (de) | 1995-03-15 | 1995-09-14 | MTG Medizinisch, technische Gerätebau GmbH, 66299 Friedrichsthal | Elektronisch geregelte Niedervakuumpumpe für die Thorax- und Wunddrainage |
GB9523253D0 (en) | 1995-11-14 | 1996-01-17 | Mediscus Prod Ltd | Portable wound treatment apparatus |
US6135116A (en) | 1997-07-28 | 2000-10-24 | Kci Licensing, Inc. | Therapeutic method for treating ulcers |
AU755496B2 (en) | 1997-09-12 | 2002-12-12 | Kci Licensing, Inc. | Surgical drape and suction head for wound treatment |
GB9719520D0 (en) | 1997-09-12 | 1997-11-19 | Kci Medical Ltd | Surgical drape and suction heads for wound treatment |
US6071267A (en) | 1998-02-06 | 2000-06-06 | Kinetic Concepts, Inc. | Medical patient fluid management interface system and method |
US6488643B1 (en) | 1998-10-08 | 2002-12-03 | Kci Licensing, Inc. | Wound healing foot wrap |
US6287316B1 (en) | 1999-03-26 | 2001-09-11 | Ethicon, Inc. | Knitted surgical mesh |
US7799004B2 (en) | 2001-03-05 | 2010-09-21 | Kci Licensing, Inc. | Negative pressure wound treatment apparatus and infection identification system and method |
US6856821B2 (en) | 2000-05-26 | 2005-02-15 | Kci Licensing, Inc. | System for combined transcutaneous blood gas monitoring and vacuum assisted wound closure |
US6991643B2 (en) | 2000-12-20 | 2006-01-31 | Usgi Medical Inc. | Multi-barbed device for retaining tissue in apposition and methods of use |
EP1257313B1 (en) | 2000-02-24 | 2004-05-12 | Venetec International, Inc. | Universal catheter anchoring system |
US6540705B2 (en) | 2001-02-22 | 2003-04-01 | Core Products International, Inc. | Ankle brace providing upper and lower ankle adjustment |
US20030091601A1 (en) * | 2001-11-13 | 2003-05-15 | Abat Inc. | Use of topical arginine to enhance wound healing |
US7846141B2 (en) | 2002-09-03 | 2010-12-07 | Bluesky Medical Group Incorporated | Reduced pressure treatment system |
EP2298338B1 (en) * | 2002-09-16 | 2012-08-22 | Agennix Incorporated | Lactoferrin compositions and methods of treatment of skin wounds |
GB0224986D0 (en) | 2002-10-28 | 2002-12-04 | Smith & Nephew | Apparatus |
US6949899B2 (en) | 2003-07-22 | 2005-09-27 | Sunonwealth Electric Machine Industry Co., Ltd. | Brushless DC motor having an AC power control device |
GB0325120D0 (en) | 2003-10-28 | 2003-12-03 | Smith & Nephew | Apparatus with actives |
GB0325126D0 (en) | 2003-10-28 | 2003-12-03 | Smith & Nephew | Apparatus with heat |
US20050208095A1 (en) * | 2003-11-20 | 2005-09-22 | Angiotech International Ag | Polymer compositions and methods for their use |
US7909805B2 (en) | 2004-04-05 | 2011-03-22 | Bluesky Medical Group Incorporated | Flexible reduced pressure treatment appliance |
US8529548B2 (en) | 2004-04-27 | 2013-09-10 | Smith & Nephew Plc | Wound treatment apparatus and method |
SG155222A1 (en) * | 2004-08-13 | 2009-09-30 | Genentech Inc | Thiazole based inhibitors of atp-utilizing enzymes |
CA2923372C (en) * | 2005-09-07 | 2019-07-30 | Smith & Nephew, Inc. | Self contained wound dressing apparatus |
DK1965763T3 (da) * | 2005-12-27 | 2020-02-10 | Univ Ramot | Stabile enzympræparater og fremgangsmåder til anvendelse heraf |
EP2081629A4 (en) * | 2006-09-28 | 2014-06-25 | Puricore Inc | DEVICE AND METHOD FOR THE TREATMENT OF WOUNDS, CAVITIES AND BONE |
WO2008088922A2 (en) * | 2007-01-19 | 2008-07-24 | Genentech, Inc. | Prevention of hydrogel viscosity loss |
US8034573B2 (en) * | 2007-11-05 | 2011-10-11 | Kci Licensing Inc. | Identification of tissue for debridement |
US8021347B2 (en) | 2008-07-21 | 2011-09-20 | Tyco Healthcare Group Lp | Thin film wound dressing |
US8007481B2 (en) | 2008-07-17 | 2011-08-30 | Tyco Healthcare Group Lp | Subatmospheric pressure mechanism for wound therapy system |
US8784790B2 (en) * | 2008-06-12 | 2014-07-22 | Medtronic Xomed, Inc. | Method for treating chronic wounds with an extracellular polymeric substance solvating system |
US8216198B2 (en) | 2009-01-09 | 2012-07-10 | Tyco Healthcare Group Lp | Canister for receiving wound exudate in a negative pressure therapy system |
US8251979B2 (en) | 2009-05-11 | 2012-08-28 | Tyco Healthcare Group Lp | Orientation independent canister for a negative pressure wound therapy device |
US20100260824A1 (en) | 2008-08-28 | 2010-10-14 | Tyco Healthcare Group Lp | Antimicrobial Foam Compositions, Articles and Methods |
US8486032B2 (en) * | 2008-12-24 | 2013-07-16 | Kci Licensing, Inc. | Reduced-pressure treatment systems and methods employing debridement mechanisms |
WO2010132605A1 (en) * | 2009-05-13 | 2010-11-18 | Protein Delivery Solutions, Llc | Pharmaceutical system for trans-membrane delivery |
US9421309B2 (en) * | 2009-06-02 | 2016-08-23 | Kci Licensing, Inc. | Reduced-pressure treatment systems and methods employing hydrogel reservoir members |
WO2013009614A2 (en) | 2011-07-08 | 2013-01-17 | The Cleveland Clinic Foundation | System and method for wound healing |
EP2750729B1 (en) | 2011-08-31 | 2015-05-27 | KCI Licensing, Inc. | Reduced-pressure treatment and debridement systems and methods |
-
2012
- 2012-08-17 EP EP12750972.7A patent/EP2750729B1/en active Active
- 2012-08-17 CN CN201711227173.7A patent/CN107854737B/zh active Active
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- 2012-08-17 EP EP15168884.3A patent/EP2957304B1/en active Active
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- 2016-06-29 JP JP2016128285A patent/JP6282693B2/ja active Active
-
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Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101257875A (zh) * | 2005-09-06 | 2008-09-03 | 泰科保健集团有限合伙公司 | 具有微型泵的独立伤口敷料 |
CN102089017A (zh) * | 2008-05-30 | 2011-06-08 | 凯希特许有限公司 | 透明减压敷料和系统 |
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WO2013032745A1 (en) | 2013-03-07 |
AU2012301427A1 (en) | 2014-02-13 |
JP6282693B2 (ja) | 2018-02-21 |
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AU2012301427B2 (en) | 2017-03-02 |
EP2957304A1 (en) | 2015-12-23 |
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CA2842958A1 (en) | 2013-03-07 |
US10172984B2 (en) | 2019-01-08 |
CA2842958C (en) | 2020-07-28 |
EP2750729A1 (en) | 2014-07-09 |
US20190192749A1 (en) | 2019-06-27 |
EP2957304B1 (en) | 2017-02-15 |
US11529453B2 (en) | 2022-12-20 |
CN107854737B (zh) | 2021-03-26 |
CN107854737A (zh) | 2018-03-30 |
JP5967675B2 (ja) | 2016-08-10 |
US20130053793A1 (en) | 2013-02-28 |
CN103747814A (zh) | 2014-04-23 |
EP2750729B1 (en) | 2015-05-27 |
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