CN103721156B - A kind of Chinese medicine preparation and preparation method for the treatment of digestive tract hemorrhage - Google Patents
A kind of Chinese medicine preparation and preparation method for the treatment of digestive tract hemorrhage Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine preparation and preparation method for the treatment of digestive tract hemorrhage, the raw material making described Chinese medicine preparation effective ingredient consists of: Fructus Aurantii, Semen Euphorbiae, Herba Melastomatis Dodecandri, Cuculus polioephalus, Fructus Piperis Longi, Endoconcha Sepiae, coriander, Radix Gossampini, Rhizoma Cyperi, Rhizoma Alpiniae Officinarum, Folium Callicarpae Formosanae, Coniogramme japonica (Thunb.) Diels, Radix Hemsleyae Macrospermae, Rhizoma Corydalis, Semen Alpiniae Katsumadai and Concha Arcae; Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and modern medicine research theory, and adopt modern advanced medical pharmaceutical technology to make, there is effect of clearing away heat and cooling blood, astringing to arrest bleeding, dispelling cold and absorbing clot, for digestive tract hemorrhage such as esophagus, stomach, intestine and small intestine and duodenums that a variety of causes causes, there is remarkable result, long action time, short treating period instant effect, safe without toxic side effect, can be widely used in the clinical treatment of digestive tract hemorrhage.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of Chinese medicine preparation and preparation method for the treatment of digestive tract hemorrhage.
Background technology
Digestive tract hemorrhage is common clinical, often because of comparatively urgency and diagnose and unclearly jeopardize patient vitals of falling ill.Digestive tract hemorrhage is divided into upper gastrointestinal hemorrhage and lower digestive tract hemorrhage usually.Upper gastrointestinal hemorrhage refers to that the digestive tract that petechia is positioned at more than Qu Shi ligament comprises the hemorrhage of the positions such as esophagus, stomach and duodenum.Lower digestive tract hemorrhage refers to the digestive tract hemorrhage occurring in below Qu Shi ligament, comprises small intestinal, coton and rectal.
The character of hemorrhage pathological changes, position, blood loss and speed are depended in the clinical manifestation of digestive tract hemorrhage, also have relation with the systemic conditions such as age, cardiorenal function of patient.
Cause hemorrhage, treatment for esophageal varices bleeding, avulsion mucous syndrome, vascular lesion and tumor etc. that the reason of upper gastrointestinal hemorrhage has esophagus, stomach and duodenal ulcer and mucosal erosion to cause usually.The diverticulitis of lower digestive tract intestinal, angiodysplasia, tumor account for, inflammation accounts for and optimum anorectal disease to cause the common cause of lower digestive tract hemorrhage to have.Acute majority of bleeding profusely shows as hematemesis, and chronic small amount bleeding is then with fecal occult blood positive performance.
For the patient of digestive tract hemorrhage, observation expression and limb skin are cold wet or warm, and recording blood pressure, pulse, amount of bleeding and urine volume per hour keep vein energy circuit also to measure central venous pressure.Keep patient respiration road unobstructed, avoid occurring surprisingly during hematemesis.
If a kind of medicine safely and effectively can be invented help patient treatment disease and will improve the therapeutic effect of digestive tract hemorrhage widely.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of digestive tract hemorrhage, selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and modern medicine research theory, and adopt modern advanced medical pharmaceutical technology to make, there is effect of clearing away heat and cooling blood, astringing to arrest bleeding, dispelling cold and absorbing clot, for digestive tract hemorrhage such as esophagus, stomach, intestine and small intestine and duodenums that a variety of causes causes, there is remarkable result, long action time, short treating period instant effect, safe without toxic side effect, can be widely used in the clinical treatment of digestive tract hemorrhage.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for digestive tract hemorrhage, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fructus Aurantii 46-74 part Semen Euphorbiae 46-74 part Herba Melastomatis Dodecandri 46-74 part Cuculus polioephalus 44-70 part
Fructus Piperis Longi 44-70 part Endoconcha Sepiae 44-70 part coriander 40-68 part Radix Gossampini 40-68 part
Rhizoma Cyperi 40-68 part Rhizoma Alpiniae Officinarum 38-65 part Folium Callicarpae Formosanae 38-65 part Coniogramme japonica (Thunb.) Diels 38-65 part
Radix Hemsleyae Macrospermae 35-60 part Rhizoma Corydalis 35-60 part Semen Alpiniae Katsumadai 33-55 part Concha Arcae 33-55 part.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fructus Aurantii 67 parts of Semen Euphorbiaes 67 parts of Herba Melastomatis Dodecandri 67 portions of Cuculus polioephalus 62 parts
Fructus Piperis Longi 62 portions of Endoconcha Sepiaes 62 parts of corianders 60 parts of Radix Gossampinis 60 parts
Rhizoma Cyperi 60 portions of Rhizoma Alpiniae Officinarums 58 portions of Folium Callicarpae Formosanaes 58 parts of Coniogramme japonica (Thunb.) Dielss 58 parts
Radix Hemsleyae Macrospermae 50 parts of Rhizoma Corydalis 50 parts of Semen Alpiniae Katsumadai 48 parts of Concha Arcaes 48 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fructus Aurantii 60 parts of Semen Euphorbiaes 60 parts of Herba Melastomatis Dodecandri 60 portions of Cuculus polioephalus 56 parts
Fructus Piperis Longi 56 portions of Endoconcha Sepiaes 56 parts of corianders 54 parts of Radix Gossampinis 54 parts
Rhizoma Cyperi 54 portions of Rhizoma Alpiniae Officinarums 53 portions of Folium Callicarpae Formosanaes 53 parts of Coniogramme japonica (Thunb.) Dielss 53 parts
Radix Hemsleyae Macrospermae 45 parts of Rhizoma Corydalis 45 parts of Semen Alpiniae Katsumadai 43 parts of Concha Arcaes 43 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fructus Aurantii 53 parts of Semen Euphorbiaes 53 parts of Herba Melastomatis Dodecandri 53 portions of Cuculus polioephalus 50 parts
Fructus Piperis Longi 50 portions of Endoconcha Sepiaes 50 parts of corianders 47 parts of Radix Gossampinis 47 parts
Rhizoma Cyperi 47 portions of Rhizoma Alpiniae Officinarums 45 portions of Folium Callicarpae Formosanaes 45 parts of Coniogramme japonica (Thunb.) Dielss 45 parts
Radix Hemsleyae Macrospermae 40 parts of Rhizoma Corydalis 40 parts of Semen Alpiniae Katsumadai 38 parts of Concha Arcaes 38 parts.
Treat a preparation method for the Chinese medicine preparation of digestive tract hemorrhage, comprise following processing step:
(1) get Fructus Aurantii, Cuculus polioephalus, Rhizoma Alpiniae Officinarum, Rhizoma Corydalis and Semen Alpiniae Katsumadai decontamination, dry, be placed in mortar, grind into powder, cross 180 order fine powders, for subsequent use;
(2) get Semen Euphorbiae, Radix Gossampini and Folium Callicarpae Formosanae decontamination to clean, dry, add 80% alcoholic solution of 5 times amount, soak 2-4 hour, heating extraction 3 hours, reclaim ethanol, filter, under filtrate simmer down to 60 DEG C of environment, the thick paste of relative density 1.20 ~ 1.25, for subsequent use;
(3) get Herba Melastomatis Dodecandri, Fructus Piperis Longi, Endoconcha Sepiae, coriander, Rhizoma Cyperi, Coniogramme japonica (Thunb.) Diels, Radix Hemsleyae Macrospermae and Concha Arcae decontamination, clean and put into container, add the distilled water of 8-12 times amount, soak after 4-5 hour, boil 3-4 hour, extract; Again add 6-8 times amount distilled water, boil 2-3 hour, extract; Finally add 4-6 times amount distilled water, heated and boiled 1-2 hour, extract; Merge three extracting solution, filter, reserved filtrate, for subsequent use;
(4) by the fine powder obtained by above-mentioned steps (1)-(3) and thick paste mixing, utilize modern advanced pharmacy science and technology, make capsule, be the Chinese medicine preparation of described treatment digestive tract hemorrhage.
The property of medicine of the present invention's Chinese medicine used is as follows:
Fructus Aurantii: bitter in the mouth, pungent, sour, warm in nature; Return spleen, stomach warp.Regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention, gastroptosis, proctoptosis, uterine prolapse.
Semen Euphorbiae: acrid in the mouth, warm in nature, poisonous; Return Liver Channel, kidney channel, large intestine channel.To relieve oedema or abdominal distension through diuresis or purgation detumescence, removing blood stasis eliminating mass.For edema, phlegm retention, stagnant distension, constipation and anuresis, blood stasis amenorrhea; External treatment stubborn dermatitis, warty vegetation.Modern medicine study confirms, the growth of the daphnetin contained by Semen Euphorbiae to staphylococcus aureus, escherichia coli, shigella flexneri and bacillus pyocyaneus has inhibitory action.
Herba Melastomatis Dodecandri: sweet in the mouth, puckery, property is put down; Enter liver,kidney,spleen, lung four warp.Heat-clearing and toxic substances removing, expelling wind and removing dampness, tonifying blood and arresting bleeding.For preventing epidemic cerebrospinal meningitis, enteritis, dysentery, lung abscess, pelvic inflammatory disease, metrorrhagia, anemia, leucorrhea, lumbago and skelalgia, rheumatic ostalgia, traumatic hemorrhage, venom.
Cuculus polioephalus: sweet in the mouth, property is put down; GUIXIN warp.Nourish tonify deficiency, removing toxic substances parasite killing, promoting blood circulation and stopping pain.Cure mainly body after being ill empty, insufficiency of vital energy and blood, skin ulcer fistula, treating swelling and pain by traumatic injury, articular instability." Zhejiang conventional medical herbs among the people " carries: " detumescence hemostasis.”
Fructus Piperis Longi: acrid in the mouth, hot in nature; Return stomach, large intestine channel.Warming spleen and stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards pain relieving.For coldness and pain in the epigastrium, vomiting, has loose bowels, migraine; External treatment is had a toothache.Amplification on Canon of Materia Medica carries: " walk cold air in the intestines and stomach, vomiting, fullness in the chest and abdomen pain.”
Endoconcha Sepiae: salty in the mouth, puckery, warm in nature; Return spleen, kidney channel.Astringing to arrest bleeding, relieving leukorrhea by astringents, antacid sore.For acid regurgitation of having a stomachache, hematemesis and epistaxis, metrorrhagia is had blood in stool, emission and spermatorrhea, leucorrhea with red and white discharge, Peptic Ulcers; External treatment bleeding due to trauma, the many pus of skin ulcer." detailed outline " carries: " main woman's blood depletion is sick, impairing the liver, hemoptysis hematochezia, and treating malaria disappears wart.Grind deposited children's's chancre into powder, variola is smelly rotten, husband's erosion of vulva, and burn is got injured by a fall hemorrhage.Charred medicinal herb with its property retained, is coated with children's congenital deformity of the tongue, thrush with Ovum Gallus domesticus Flavus, applies glossoncus blood and goes out Ru Quan, control sore throat with Vermilion nasal insufflation with Pollen Typhae end, blows ear control Ting ear and have pus and deafness with Moschus.”
Coriander: acrid in the mouth, warm in nature; Enter lung, stomach warp.Deliver rash, stomach invigorating.For measles without adequate eruption, catch a cold lossless, dyspepsia, inappetence.
Radix Gossampini: acrid in the mouth, sweet, property is put down.Can wet and in, resolving depression of regulating the flow of vital energy.Cure mainly taste turbid damp not change, eat gastral cavity less vexed, diarrhoea or dysentery stomachache.Modern medicine study confirms, Radix Gossampini has the effect of liver heat removing and eyesight improving, makes people's life lengthening, physical and mental health.
Rhizoma Cyperi: acrid in the mouth, micro-hardship, property is put down; Enter liver, tri-jiao channel.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain.Li Gao: " control all gas, the stomachache and cholera is vomited and diarrhoea, kidney qi, bladder is cold, removing stagnancy of indigested food and making QI downward.”
Rhizoma Alpiniae Officinarum: acrid in the mouth, hot in nature; Return spleen, stomach warp.Warming spleen and stomach for dispelling cold, regulating QI to relieve pain.Cure mainly coldness and pain in the epigastrium, vomiting, eructation.Modern medicine study confirms, Rhizoma Alpiniae Officinarum water extract and ether extract have obvious choleretic effect and obvious analgesic activity.
Folium Callicarpae Formosanae: bitter in the mouth, puckery, property is put down.Hemostasis dissipating blood stasis, antiinflammatory.For epistaxis, spitting of blood, gastrointestinal hemorrhage, metrorrhagia, upper respiratory tract infection, tonsillitis, pneumonia, bronchitis; Traumatic hemorrhage is controlled in external, burn." illustrated handbook planted by middle traditional Chinese medicines " carries: " hemorrhage to esophageal vein, intestine gastric ulcer is hemorrhage, epistaxis, wound hemorrhage, pneumorrhagia and have tooth pulled out and hemorrhagely all have good effect.”
Coniogramme japonica (Thunb.) Diels: micro-pungent, the micro-hardship of taste, cool in nature, return Liver Channel.Expelling wind and removing dampness, loose blood and relieving pain, heat-clearing and toxic substances removing.Cure mainly rheumatic arthritis, abdominal pain due to blood stasis, amenorrhea, traumatic injury, conjunctival congestion and swelling pain, acute mastitis, various toxic swelling from the beginning of.
Radix Hemsleyae Macrospermae: bitter in the mouth, cold in nature, slightly poisonous.Heat-clearing and toxic substances removing, benefiting stomach and stopping pain.For stomachache, Peptic Ulcers, upper respiratory tract infection, bronchitis, pneumonia, bacillary dysentery, enteritis, urinary system infection, septicemia and other multi-infections." Kunming conventional medical herbs among the people " carries: " stomach invigorating, pain relieving, antiinflammatory, hemostasis.Control abdominal distention, dysentery, hepatitis, prostatitis, traumatic hemorrhage.”
Rhizoma Corydalis: acrid in the mouth, hardship, warm in nature, nontoxic; Enter pericardium, liver, spleen, lung meridian.Promoting blood circulation to remove blood stasis, regulating QI to relieve pain.Cure mainly all pains of trusted subordinate's waist knee joint, menoxenia, lump in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.Modern medicine study confirms, Rhizoma Corydalis can suppress gastric secretion and prevent and treat Peptic Ulcers, has protective effect to the intestines and stomach.
Semen Alpiniae Katsumadai: acrid in the mouth, warm in nature; Return spleen, stomach warp.Drying damp and strengthening spleen, stomach warming preventing or arresting vomiting.For internal retention of cold wetness, distension and fullness in the abdomen cold type of pain, belch vomiting, anorexia." detailed outline " carries: " control communicable subtropical diseases algid malaria, Sunstroke is told down and let out dysentery, dysphagia and regurgitation, feeling of fullness acid regurgitation, and phlegm retention is gathered, married woman's malignant histocytosis leukorrhagia, and except cold dampness, dissipating depression of QI dispelling the stagnated QI, kills ichthyosacrotoxin.”
Concha Arcae: salty in the mouth, property is put down; Return lung, stomach, Liver Channel.Expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache.For the long-pending knot of pertinacious phlegm, sticky difficulty is coughed up, goiter, scrofula, lump in the abdomen mass in the abdomen, stomachache pantothenic acid." medical center collection will " carries: " remove all accumulation of phlegm, accumulation of blood, air parcel, broken lump in the abdomen, attacks scrofula.”
The present invention compared with prior art, has following beneficial effect:
Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and modern medicine research theory, and adopt modern advanced medical pharmaceutical technology to make, there is effect of clearing away heat and cooling blood, astringing to arrest bleeding, dispelling cold and absorbing clot, for digestive tract hemorrhage such as esophagus, stomach, intestine and small intestine and duodenums that a variety of causes causes, there is remarkable result, long action time, short treating period instant effect, safe without toxic side effect, can be widely used in the clinical treatment of digestive tract hemorrhage.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Fructus Aurantii 72g Semen Euphorbiae 72g Herba Melastomatis Dodecandri 72g Cuculus polioephalus 68g
Fructus Piperis Longi 68g Endoconcha Sepiae 68g coriander 66g Radix Gossampini 66g
Rhizoma Cyperi 66g Rhizoma Alpiniae Officinarum 63g Folium Callicarpae Formosanae 63g Coniogramme japonica (Thunb.) Diels 63g
Radix Hemsleyae Macrospermae 55g Rhizoma Corydalis 55g Semen Alpiniae Katsumadai 53g Concha Arcae 53g.
The preparation method of Chinese medicine preparation of the present invention, comprises following processing step:
(1) get Fructus Aurantii, Cuculus polioephalus, Rhizoma Alpiniae Officinarum, Rhizoma Corydalis and Semen Alpiniae Katsumadai decontamination, dry, be placed in mortar, grind into powder, cross 180 order fine powders, for subsequent use;
(2) get Semen Euphorbiae, Radix Gossampini and Folium Callicarpae Formosanae decontamination to clean, dry, add 80% alcoholic solution of 5 times amount, soak 2-4 hour, heating extraction 3 hours, reclaim ethanol, filter, under filtrate simmer down to 60 DEG C of environment, the thick paste of relative density 1.20 ~ 1.25, for subsequent use;
(3) get Herba Melastomatis Dodecandri, Fructus Piperis Longi, Endoconcha Sepiae, coriander, Rhizoma Cyperi, Coniogramme japonica (Thunb.) Diels, Radix Hemsleyae Macrospermae and Concha Arcae decontamination, clean and put into container, add the distilled water of 8-12 times amount, soak after 4-5 hour, boil 3-4 hour, extract; Again add 6-8 times amount distilled water, boil 2-3 hour, extract; Finally add 4-6 times amount distilled water, heated and boiled 1-2 hour, extract; Merge three extracting solution, filter, reserved filtrate, for subsequent use;
(4) by the fine powder obtained by above-mentioned steps (1)-(3) and thick paste mixing, utilize modern advanced pharmacy science and technology, make capsule, be the Chinese medicine preparation of described treatment digestive tract hemorrhage.
Usage and dosage: oral, each 2, every day 3 times, within 5 days, be a course for the treatment of, 3 to 5 courses for the treatment of can fully recover; The person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Fructus Aurantii 67g Semen Euphorbiae 67g Herba Melastomatis Dodecandri 67g Cuculus polioephalus 62g
Fructus Piperis Longi 62g Endoconcha Sepiae 62g coriander 60g Radix Gossampini 60g
Rhizoma Cyperi 60g Rhizoma Alpiniae Officinarum 58g Folium Callicarpae Formosanae 58g Coniogramme japonica (Thunb.) Diels 58g
Radix Hemsleyae Macrospermae 50g Rhizoma Corydalis 50g Semen Alpiniae Katsumadai 48g Concha Arcae 48g.
The present embodiment Chinese drugs agentia preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Fructus Aurantii 60g Semen Euphorbiae 60g Herba Melastomatis Dodecandri 60g Cuculus polioephalus 56g
Fructus Piperis Longi 56g Endoconcha Sepiae 56g coriander 54g Radix Gossampini 54g
Rhizoma Cyperi 54g Rhizoma Alpiniae Officinarum 53g Folium Callicarpae Formosanae 53g Coniogramme japonica (Thunb.) Diels 53g
Radix Hemsleyae Macrospermae 45g Rhizoma Corydalis 45g Semen Alpiniae Katsumadai 43g Concha Arcae 43g.
The present embodiment Chinese drugs agentia preparation method processing step and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Fructus Aurantii 53g Semen Euphorbiae 53g Herba Melastomatis Dodecandri 53g Cuculus polioephalus 50g
Fructus Piperis Longi 50g Endoconcha Sepiae 50g coriander 47g Radix Gossampini 47g
Rhizoma Cyperi 47g Rhizoma Alpiniae Officinarum 45g Folium Callicarpae Formosanae 45g Coniogramme japonica (Thunb.) Diels 45g
Radix Hemsleyae Macrospermae 40g Rhizoma Corydalis 40g Semen Alpiniae Katsumadai 38g Concha Arcae 38g.
The present embodiment Chinese drugs agentia preparation method processing step and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of digestive tract hemorrhage, select Diagnosing Gastrointestinal Bleeding 360 example to carry out clinical observation, patient is divided into two groups at random, treatment group 180 example, wherein man 92 example, women 88 example, age 25-60 year, 42.3 years old mean age, course of disease 1-3 month; Matched group 180 example, wherein man 90 example, women 90 example, age 26-60 year, 41.2 years old mean age, course of disease 1-3 month; Two groups of patient medical record are basically identical, without significant difference, have comparability, keep on a diet all on request for two groups.
2, medication is selected:
Treatment group person suffers from and takes Chinese medicine preparation of the present invention, and oral, each 2, every day 3 times 5 days is a course for the treatment of, and taking 3 to 5 courses for the treatment of continuously can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes stomach-recovering capsule, by specification use, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, Outcome measure:
Cure: the symptom digestive tract hemorrhage transference cure such as to spit blood, have blood in stool, digestive tract recovers normal function.
Take a turn for the better: above-mentioned symptom is alleviated to some extent.
Invalid: symptom is unchanged.
4, therapeutic outcome:
Treatment group: cure 123 examples, take a turn for the better 50 examples, and invalid 7 examples, cure rate is 68.3%, and total effective rate is 96.1%.
Matched group: cure 75 examples, take a turn for the better 53 examples, and invalid 52 examples, cure rate is 41.7%, and total effective rate is 71.1%.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
5, model case citing:
(1) certain is connected, man, 56 years old, peasant, Hunan people from Ningxiang.Start to occur epigastrium pain without obvious inducement before patient admits, in paroxysmal dull pain, about 10 minutes at every turn, without radiating pain, separate melena 1 time, amount is few, be about 100 grams, do not give attention, after again there is melena 3 times, amount is the same, and without fear of cold heating, random thoughts are felt sick, without vomiting, have dizziness headache, weak, diagnosis and treatment of being admitted to hospital are upper gastrointestinal hemorrhage.Patient takes 2 courses for the treatment of of Chinese medicine preparation of the present invention, and conditions of patients obviously alleviates, and continues to take 2 courses for the treatment of, and conditions of patients is fully recovered, and follows up a case by regular visits to and has no recurrence.
(2) Wei, female, 38 years old, remembers, Yinchuan of Ningxia Province people.Row's cerise hemafecia is there is repeatedly in patient without obvious inducement, row gastroscope of being admitted to hospital prompting pyloric cap is to kiss property ulcer, and have a blood test Lactoferrin 46g/l, occurs that vomiting cerise gastric content is about 500ml, containing food and sludged blood, companion row hemafecia, about 2000ml, companion is dizzy, malaise, after give red cells transfusion 2 unit, suit the medicine to the illness Supporting Therapy (specifically not quite clear), less effective.Rear doctor gives after Chinese medicine preparation of the present invention takes, and taking a turn for the better appears in second day state of an illness, and after taking 4 courses for the treatment of, patient returns to one's perfect health.
(3) in certain, man, 32 years old, workman, Shandong Zibo people.Patient suffers from diarrhoea because diet causes accidentally and suffers from abdominal pain, and defecating rare, is kermesinus or black watery stool, weak with dizziness, has no and alleviate after rest, and admission examination patient mind is clear, and neurolysis, cardiopulmonary are without exception, and abdomen is soft without tenderness and rebound tenderness, borborygmus 9 beats/min.Skin elasticity can, skin temperature is normal, routine blood test: HGB103g/l, remaining roughly normal, is digestive tract hemorrhage after diagnosing.After taking 4 courses for the treatment of of Chinese medicine preparation of the present invention, conditions of patients is fully recovered, and has no recurrence.
Claims (5)
1. treat a Chinese medicine preparation for digestive tract hemorrhage, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fructus Aurantii 46-74 part Semen Euphorbiae 46-74 part Herba Melastomatis Dodecandri 46-74 part Cuculus polioephalus 44-70 part
Fructus Piperis Longi 44-70 part Endoconcha Sepiae 44-70 part coriander 40-68 part Radix Gossampini 40-68 part
Rhizoma Cyperi 40-68 part Rhizoma Alpiniae Officinarum 38-65 part Folium Callicarpae Formosanae 38-65 part Coniogramme japonica (Thunb.) Diels 38-65 part
Radix Hemsleyae Macrospermae 35-60 part Rhizoma Corydalis 35-60 part Semen Alpiniae Katsumadai 33-55 part Concha Arcae 33-55 part.
2. a kind of Chinese medicine preparation for the treatment of digestive tract hemorrhage according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fructus Aurantii 67 parts of Semen Euphorbiaes 67 parts of Herba Melastomatis Dodecandri 67 portions of Cuculus polioephalus 62 parts
Fructus Piperis Longi 62 portions of Endoconcha Sepiaes 62 parts of corianders 60 parts of Radix Gossampinis 60 parts
Rhizoma Cyperi 60 portions of Rhizoma Alpiniae Officinarums 58 portions of Folium Callicarpae Formosanaes 58 parts of Coniogramme japonica (Thunb.) Dielss 58 parts
Radix Hemsleyae Macrospermae 50 parts of Rhizoma Corydalis 50 parts of Semen Alpiniae Katsumadai 48 parts of Concha Arcaes 48 parts.
3. a kind of Chinese medicine preparation for the treatment of digestive tract hemorrhage according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fructus Aurantii 60 parts of Semen Euphorbiaes 60 parts of Herba Melastomatis Dodecandri 60 portions of Cuculus polioephalus 56 parts
Fructus Piperis Longi 56 portions of Endoconcha Sepiaes 56 parts of corianders 54 parts of Radix Gossampinis 54 parts
Rhizoma Cyperi 54 portions of Rhizoma Alpiniae Officinarums 53 portions of Folium Callicarpae Formosanaes 53 parts of Coniogramme japonica (Thunb.) Dielss 53 parts
Radix Hemsleyae Macrospermae 45 parts of Rhizoma Corydalis 45 parts of Semen Alpiniae Katsumadai 43 parts of Concha Arcaes 43 parts.
4. a kind of Chinese medicine preparation for the treatment of digestive tract hemorrhage according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fructus Aurantii 53 parts of Semen Euphorbiaes 53 parts of Herba Melastomatis Dodecandri 53 portions of Cuculus polioephalus 50 parts
Fructus Piperis Longi 50 portions of Endoconcha Sepiaes 50 parts of corianders 47 parts of Radix Gossampinis 47 parts
Rhizoma Cyperi 47 portions of Rhizoma Alpiniae Officinarums 45 portions of Folium Callicarpae Formosanaes 45 parts of Coniogramme japonica (Thunb.) Dielss 45 parts
Radix Hemsleyae Macrospermae 40 parts of Rhizoma Corydalis 40 parts of Semen Alpiniae Katsumadai 38 parts of Concha Arcaes 38 parts.
5. as described in any one of claim 1-4, treat a preparation method for the Chinese medicine preparation of digestive tract hemorrhage, it is characterized in that: comprise following processing step:
(1) get Fructus Aurantii, Cuculus polioephalus, Rhizoma Alpiniae Officinarum, Rhizoma Corydalis and Semen Alpiniae Katsumadai decontamination, dry, be placed in mortar, grind into powder, cross 180 order fine powders, for subsequent use;
(2) get Semen Euphorbiae, Radix Gossampini and Folium Callicarpae Formosanae decontamination to clean, dry, add 80% alcoholic solution of 5 times amount, soak 2-4 hour, heating extraction 3 hours, reclaim ethanol, filter, under filtrate simmer down to 60 DEG C of environment, the thick paste of relative density 1.20 ~ 1.25, for subsequent use;
(3) get Herba Melastomatis Dodecandri, Fructus Piperis Longi, Endoconcha Sepiae, coriander, Rhizoma Cyperi, Coniogramme japonica (Thunb.) Diels, Radix Hemsleyae Macrospermae and Concha Arcae decontamination, clean and put into container, add the distilled water of 8-12 times amount, soak after 4-5 hour, boil 3-4 hour, extract; Again add 6-8 times amount distilled water, boil 2-3 hour, extract; Finally add 4-6 times amount distilled water, heated and boiled 1-2 hour, extract; Merge three extracting solution, filter, reserved filtrate, for subsequent use;
(4) by the fine powder obtained by above-mentioned steps (1)-(3), thick paste and filtrate mixing, utilize modern advanced pharmacy science and technology, make capsule, be the Chinese medicine preparation of described treatment digestive tract hemorrhage.
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| CN1686308A (en) * | 2005-03-21 | 2005-10-26 | 李丰中 | Medicine for treating gastritis and gastrelcoma and its preparation method |
| CN1966036A (en) * | 2006-11-25 | 2007-05-23 | 李勇奇 | Chinese medicine for treating gastrointestinal disease and preparation method thereof |
| CN103083628A (en) * | 2011-11-01 | 2013-05-08 | 焦国荣 | Medicine composition for treating gastric and duodenal ulcer and preparation method thereof |
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| CN1686308A (en) * | 2005-03-21 | 2005-10-26 | 李丰中 | Medicine for treating gastritis and gastrelcoma and its preparation method |
| CN1966036A (en) * | 2006-11-25 | 2007-05-23 | 李勇奇 | Chinese medicine for treating gastrointestinal disease and preparation method thereof |
| CN103083628A (en) * | 2011-11-01 | 2013-05-08 | 焦国荣 | Medicine composition for treating gastric and duodenal ulcer and preparation method thereof |
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