CN103721156A - Traditional Chinese medicine preparation for treating gastrointestinal bleeding and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for treating gastrointestinal bleeding and preparation method thereof Download PDF

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CN103721156A
CN103721156A CN201410012293.5A CN201410012293A CN103721156A CN 103721156 A CN103721156 A CN 103721156A CN 201410012293 A CN201410012293 A CN 201410012293A CN 103721156 A CN103721156 A CN 103721156A
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rhizoma
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CN103721156B (en
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王玉霞
鲁守东
李克波
王永雪
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Buck (Tangshan) Biotechnology Co., Ltd.
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王玉霞
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Abstract

The invention relates to a traditional Chinese medicine preparation for treating gastrointestinal bleeding and a preparation method thereof. Active ingredients of the traditional Chinese medicine preparation are prepared from the following raw materials: fructus aurantii, moleplant seed, Herba Melastomatis Dodecandri, Rhododendron, fructus piperis longi, cuttlebone, Chinese parsley, root of common bombax, Cyperus rotundus, rhizoma galangae, folium callicarpae pedunculalae, bamboo fern, hemsleya amabilis, corydalis tuber, Alpinia katsumadai and concha arcae. The traditional Chinese medicine preparation provided by the invention is suitable in compatibility of selected medicinal materials, conforms to the theory of traditional Chinese medicine and modern medicine research, is prepared by adopting the modern advanced medical and pharmaceutical technologies, has the efficacies of removing heat to cool blood, astringing to stop bleeding, and dispelling cold and blood stasis, has a significant effect on esophagus, stomach, large intestine and small intestine, dodecadactylon and other gastrointestinal bleeding caused by various reasons, is long in acting time, short in course of treatment, quick in effect, and safe without toxic or side effects, and can be widely applied to the clinical treatment of the gastrointestinal bleeding.

Description

A kind of Chinese medicine preparation and preparation method for the treatment of digestive tract hemorrhage
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of Chinese medicine preparation and preparation method for the treatment of digestive tract hemorrhage.
Background technology
Digestive tract hemorrhage is common clinical, often because falling ill urgency and diagnose the unclear patient's of jeopardizing life.Digestive tract hemorrhage is divided into upper gastrointestinal hemorrhage and lower digestive tract hemorrhage conventionally.Upper gastrointestinal hemorrhage refers to that the digestive tract that petechia is positioned at more than Qu Shi ligament comprises the hemorrhage of the positions such as esophagus, stomach and duodenum.Lower digestive tract hemorrhage refers to the digestive tract hemorrhage occurring in below Qu Shi ligament, comprises small intestinal, coton and rectal.
Character, position, blood loss and the speed of hemorrhage pathological changes is depended in the clinical manifestation of digestive tract hemorrhage, also has relation with systemic conditions such as age of patient, cardiorenal functions.
That the reason that causes upper gastrointestinal hemorrhage has that esophagus, stomach and duodenal ulcer and mucosal erosion cause conventionally is hemorrhage, treatment for esophageal varices bleeding, avulsion mucous syndrome, vascular lesion and tumor etc.Cause the common cause of lower digestive tract hemorrhage to have that diverticulitis, angiodysplasia, the tumor of lower digestive tract intestinal account for, inflammation accounts for and optimum anorectal disease.The acute majority of bleeding profusely shows as hematemesis, and chronic small amount bleeding is with the positive performance of feces occult blood.
For the patient of digestive tract hemorrhage, it is cold wet or warm observing expression and limb skin, and recording blood pressure, pulse, amount of bleeding and urine amount per hour, keep vein energy circuit and measure central venous pressure.Keep patient respiration road unobstructed, while avoiding hematemesis, occur unexpected.
If can invent a kind of medicine safely and effectively helps patient treatment disease and will improve widely the therapeutic effect of digestive tract hemorrhage.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of digestive tract hemorrhage, the selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meet Chinese medicine and modern medicine research theory, and adopt modern advanced medical pharmaceutical technology to make, the effect with clearing away heat and cooling blood, astringing to arrest bleeding, dispelling cold and absorbing clot, the digestive tract hemorrhage such as the esophagus causing for a variety of causes, stomach, intestine and small intestine and duodenum have remarkable result, long action time, short treating period instant effect, safe without toxic side effect, can be widely used in the clinical treatment of digestive tract hemorrhage.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for digestive tract hemorrhage, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fructus Aurantii 46-74 part Semen Euphorbiae 46-74 part Herba Melastomatis Dodecandri 46-74 part Cuculus polioephalus 44-70 part
Fructus Piperis Longi 44-70 part Endoconcha Sepiae 44-70 part coriander 40-68 part Radix Gossampini 40-68 part
Rhizoma Cyperi 40-68 part Rhizoma Alpiniae Officinarum 38-65 part Folium Callicarpae Formosanae 38-65 part Coniogramme japonica (Thunb.) Diels 38-65 part
Radix Hemsleyae Macrospermae 35-60 part Rhizoma Corydalis 35-60 part Semen Alpiniae Katsumadai 33-55 part Concha Arcae 33-55 part.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
62 parts of 67 portions of Cuculus polioephalus of 67 parts of Herba Melastomatis Dodecandri of 67 parts of Semen Euphorbiaes of Fructus Aurantii
60 parts of 60 parts of Radix Gossampinis of 62 parts of corianders of 62 portions of Endoconcha Sepiaes of Fructus Piperis Longi
58 parts of 58 parts of Coniogramme japonica (Thunb.) Dielss of 58 portions of Folium Callicarpae Formosanaes of 60 portions of Rhizoma Alpiniae Officinarums of Rhizoma Cyperi
48 parts of 48 parts of Concha Arcaes of 50 parts of Semen Alpiniae Katsumadai of 50 parts of Rhizoma Corydalis of Radix Hemsleyae Macrospermae.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
56 parts of 60 portions of Cuculus polioephalus of 60 parts of Herba Melastomatis Dodecandri of 60 parts of Semen Euphorbiaes of Fructus Aurantii
54 parts of 54 parts of Radix Gossampinis of 56 parts of corianders of 56 portions of Endoconcha Sepiaes of Fructus Piperis Longi
53 parts of 53 parts of Coniogramme japonica (Thunb.) Dielss of 53 portions of Folium Callicarpae Formosanaes of 54 portions of Rhizoma Alpiniae Officinarums of Rhizoma Cyperi
43 parts of 43 parts of Concha Arcaes of 45 parts of Semen Alpiniae Katsumadai of 45 parts of Rhizoma Corydalis of Radix Hemsleyae Macrospermae.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
50 parts of 53 portions of Cuculus polioephalus of 53 parts of Herba Melastomatis Dodecandri of 53 parts of Semen Euphorbiaes of Fructus Aurantii
47 parts of 47 parts of Radix Gossampinis of 50 parts of corianders of 50 portions of Endoconcha Sepiaes of Fructus Piperis Longi
45 parts of 45 parts of Coniogramme japonica (Thunb.) Dielss of 45 portions of Folium Callicarpae Formosanaes of 47 portions of Rhizoma Alpiniae Officinarums of Rhizoma Cyperi
38 parts of 38 parts of Concha Arcaes of 40 parts of Semen Alpiniae Katsumadai of 40 parts of Rhizoma Corydalis of Radix Hemsleyae Macrospermae.
Treat a preparation method for the Chinese medicine preparation of digestive tract hemorrhage, comprise following processing step:
(1) get Fructus Aurantii, Cuculus polioephalus, Rhizoma Alpiniae Officinarum, Rhizoma Corydalis and Semen Alpiniae Katsumadai decontamination, dry, be placed in mortar, grind into powder, cross 180 order fine powders, standby;
(2) get Semen Euphorbiae, Radix Gossampini and Folium Callicarpae Formosanae decontamination and clean, dry, add 80% alcoholic solution of 5 times of amounts, soak 2-4 hour, heating extraction 3 hours, reclaims ethanol, filters, and under 60 ℃ of environment of filtrate simmer down to, the thick paste of relative density 1.20~1.25, standby;
(3) get Herba Melastomatis Dodecandri, Fructus Piperis Longi, Endoconcha Sepiae, coriander, Rhizoma Cyperi, Coniogramme japonica (Thunb.) Diels, Radix Hemsleyae Macrospermae and Concha Arcae decontamination, clean and put into container, the distilled water that adds 8-12 doubly to measure, soaked after 4-5 hour, boiled 3-4 hour, extracted; Again add 6-8 doubly to measure distilled water, boil 2-3 hour, extract; Finally add 4-6 doubly to measure distilled water, heated and boiled 1-2 hour, extracts; Merge three times extracting solution, filter, reserved filtrate, standby;
(4) above-mentioned steps (1)-(3) prepared fine powder and thick paste are mixed, utilize modern advanced pharmacy science and technology, make capsule, be the Chinese medicine preparation of described treatment digestive tract hemorrhage.
The property of medicine of the present invention's Chinese medicine used is as follows:
Fructus Aurantii: bitter in the mouth, pungent, sour, warm in nature; Return spleen, stomach warp.Regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention, gastroptosis, proctoptosis, uterine prolapse.
Semen Euphorbiae: acrid in the mouth, warm in nature, poisonous; Return Liver Channel, kidney channel, large intestine channel.The detumescence of relieving oedema or abdominal distension through diuresis or purgation, removing blood stasis eliminating mass.For edema, phlegm retention, stagnant distension, constipation and anuresis, blood stasis amenorrhea; External treatment stubborn dermatitis, warty vegetation.Modern medicine study confirmation, the contained daphnetin of Semen Euphorbiae has inhibitory action to the growth of staphylococcus aureus, escherichia coli, shigella flexneri and bacillus pyocyaneus.
Herba Melastomatis Dodecandri: sweet in the mouth, puckery, property is flat; Enter liver,kidney,spleen, lung four warps.Heat-clearing and toxic substances removing, expelling wind and removing dampness, tonifying blood and arresting bleeding.Be used for preventing epidemic cerebrospinal meningitis, enteritis, dysentery, lung abscess, pelvic inflammatory disease, metrorrhagia, anemia, leucorrhea, lumbago and skelalgia, rheumatic ostalgia, traumatic hemorrhage, venom.
Cuculus polioephalus: sweet in the mouth, property is flat; GUIXIN warp.Nourish tonify deficiency, removing toxic substances parasite killing, promoting blood circulation and stopping pain.Cure mainly body void after being ill, insufficiency of vital energy and blood, skin ulcer fistula, treating swelling and pain by traumatic injury, articular instability.< < Zhejiang conventional medical herbs > > among the people carries: " detumescence hemostasis.”
Fructus Piperis Longi: acrid in the mouth, hot in nature; Return stomach, large intestine channel.Warming spleen and stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards pain relieving.For coldness and pain in the epigastrium, vomiting, has loose bowels, migraine; External treatment toothache.< < Amplification on Materia Medica > > carries: " walk cold air in the intestines and stomach, vomiting, fullness in the chest and abdomen pain.”
Endoconcha Sepiae: salty in the mouth, puckery, warm in nature; Return spleen, kidney channel.Astringing to arrest bleeding, relieving leukorrhea by astringents, antacid sore.Be used for the acid regurgitation of having a stomachache, hematemesis and epistaxis, metrorrhagia is had blood in stool, emission and spermatorrhea, leucorrhea with red and white discharge, Peptic Ulcers; External treatment bleeding due to trauma, the many pus of skin ulcer.< < detailed outline > > carries: " main woman's blood depletion is sick, impairing the liver, hemoptysis hematochezia, the treating malaria wart that disappears.Grind into powder and apply children's's chancre, variola is smelly rotten, husband's erosion of vulva, and burn, gets injured by a fall hemorrhage.Charred medicinal herb with its property retained, is coated with children's's congenital deformity of the tongue, thrush with Ovum Gallus domesticus Flavus, applies glossoncus blood go out Ru Quan with Pollen Typhae end, with Vermilion nasal insufflation, controls sore throat, blows ear control Ting ear and have pus and deafness with Moschus.”
Coriander: acrid in the mouth, warm in nature; Enter lung, stomach warp.Deliver rash, stomach invigorating.For measles without adequate eruption, catch a cold lossless, dyspepsia, inappetence.
Radix Gossampini: acrid in the mouth, sweet, property is flat.Can be wet and in, the resolving depression of regulating the flow of vital energy.Cure mainly taste turbid damp and do not change, eat less gastral cavity vexed, diarrhoea or dysentery stomachache.Modern medicine study confirmation, Radix Gossampini has the effect of liver heat removing and eyesight improving, makes people's life lengthening, physical and mental health.
Rhizoma Cyperi: acrid in the mouth, micro-hardship, property is flat; Enter liver, tri-jiao channel.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache.Li Gao: " control all gas, and cholera vomiting and diarrhoea stomachache, kidney qi, bladder is cold, removing stagnancy of indigested food and making QI downward.”
Rhizoma Alpiniae Officinarum: acrid in the mouth, hot in nature; Return spleen, stomach warp.Warming spleen and stomach for dispelling cold, regulating QI to relieve pain.Cure mainly coldness and pain in the epigastrium, vomiting, eructation.Modern medicine study confirmation, Rhizoma Alpiniae Officinarum water extract and ether extract have obvious choleretic effect and obvious analgesic activity.
Folium Callicarpae Formosanae: bitter in the mouth, puckery, property is flat.Hemostasis dissipating blood stasis, antiinflammatory.For epistaxis, spitting of blood, gastrointestinal hemorrhage, metrorrhagia, upper respiratory tract infection, tonsillitis, pneumonia, bronchitis; Traumatic hemorrhage is controlled in external, burn.In < <, traditional Chinese medicines are planted illustrated handbook > > and are carried: " hemorrhage to esophageal vein, intestine gastric ulcer is hemorrhage, epistaxis, wound hemorrhage, pneumorrhagia and the hemorrhage good effect that all has of having tooth pulled out.”
Coniogramme japonica (Thunb.) Diels: micro-pungent, the micro-hardship of taste, cool in nature, return Liver Channel.Expelling wind and removing dampness, loose blood and relieving pain, heat-clearing and toxic substances removing.Cure mainly rheumatic arthritis, abdominal pain due to blood stasis, amenorrhea, traumatic injury, conjunctival congestion and swelling pain, acute mastitis, various toxic swellings from the beginning of.
Radix Hemsleyae Macrospermae: bitter in the mouth, cold in nature, slightly poisonous.Heat-clearing and toxic substances removing, benefiting stomach and stopping pain.For stomachache, Peptic Ulcers, upper respiratory tract infection, bronchitis, pneumonia, bacillary dysentery, enteritis, urinary system infection, septicemia and other multi-infections.< < Kunming conventional medical herbs > > among the people carries: " stomach invigorating, pain relieving, antiinflammatory, hemostasis.Control abdominal distention, dysentery, hepatitis, prostatitis, traumatic hemorrhage.”
Rhizoma Corydalis: acrid in the mouth, hardship, warm in nature, nontoxic; Enter pericardium, liver, spleen, lung meridian.Promoting blood circulation to remove blood stasis, regulating QI to relieve pain.Cure mainly all pains of trusted subordinate's waist knee joint, menoxenia, lump in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.Modern medicine study confirmation, Rhizoma Corydalis can suppress gastric secretion and prevent and treat Peptic Ulcers, and the intestines and stomach is had to protective effect.
Semen Alpiniae Katsumadai: acrid in the mouth, warm in nature; Return spleen, stomach warp.Drying damp and strengthening spleen, stomach warming preventing or arresting vomiting.For internal retention of cold wetness, distension and fullness in the abdomen cold type of pain, belch vomiting, anorexia.< < detailed outline > > carries: " control communicable subtropical diseases algid malaria, Sunstroke is told down and let out dysentery, dysphagia and regurgitation; feeling of fullness acid regurgitation, and phlegm retention is gathered, married woman's malignant histocytosis leukorrhagia; except cold dampness, dissipating depression of QI dispelling the stagnated QI, kills ichthyosacrotoxin.”
Concha Arcae: salty in the mouth, property is flat; Return lung, stomach, Liver Channel.Expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache.For the long-pending knot of pertinacious phlegm, sticky difficulty is coughed up, goiter, scrofula, lump in the abdomen mass in the abdomen, stomachache pantothenic acid.< < medical center collection wants > > to carry: " remove all accumulation of phlegm, accumulation of blood, air parcel, broken lump in the abdomen, attacks scrofula.”
The present invention compared with prior art, has following beneficial effect:
The selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meet Chinese medicine and modern medicine research theory, and adopt modern advanced medical pharmaceutical technology to make, the effect with clearing away heat and cooling blood, astringing to arrest bleeding, dispelling cold and absorbing clot, the digestive tract hemorrhage such as the esophagus causing for a variety of causes, stomach, intestine and small intestine and duodenum have remarkable result, long action time, short treating period instant effect, safe without toxic side effect, can be widely used in the clinical treatment of digestive tract hemorrhage.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Fructus Aurantii 72g Semen Euphorbiae 72g Herba Melastomatis Dodecandri 72g Cuculus polioephalus 68g
Fructus Piperis Longi 68g Endoconcha Sepiae 68g coriander 66g Radix Gossampini 66g
Rhizoma Cyperi 66g Rhizoma Alpiniae Officinarum 63g Folium Callicarpae Formosanae 63g Coniogramme japonica (Thunb.) Diels 63g
Radix Hemsleyae Macrospermae 55g Rhizoma Corydalis 55g Semen Alpiniae Katsumadai 53g Concha Arcae 53g.
The preparation method of Chinese medicine preparation of the present invention, comprises following processing step:
(1) get Fructus Aurantii, Cuculus polioephalus, Rhizoma Alpiniae Officinarum, Rhizoma Corydalis and Semen Alpiniae Katsumadai decontamination, dry, be placed in mortar, grind into powder, cross 180 order fine powders, standby;
(2) get Semen Euphorbiae, Radix Gossampini and Folium Callicarpae Formosanae decontamination and clean, dry, add 80% alcoholic solution of 5 times of amounts, soak 2-4 hour, heating extraction 3 hours, reclaims ethanol, filters, and under 60 ℃ of environment of filtrate simmer down to, the thick paste of relative density 1.20~1.25, standby;
(3) get Herba Melastomatis Dodecandri, Fructus Piperis Longi, Endoconcha Sepiae, coriander, Rhizoma Cyperi, Coniogramme japonica (Thunb.) Diels, Radix Hemsleyae Macrospermae and Concha Arcae decontamination, clean and put into container, the distilled water that adds 8-12 doubly to measure, soaked after 4-5 hour, boiled 3-4 hour, extracted; Again add 6-8 doubly to measure distilled water, boil 2-3 hour, extract; Finally add 4-6 doubly to measure distilled water, heated and boiled 1-2 hour, extracts; Merge three times extracting solution, filter, reserved filtrate, standby;
(4) above-mentioned steps (1)-(3) prepared fine powder and thick paste are mixed, utilize modern advanced pharmacy science and technology, make capsule, be the Chinese medicine preparation of described treatment digestive tract hemorrhage.
Usage and dosage: oral, each 2 every day 3 times, 5 days is a course for the treatment of, and can fully recover 3 to 5 courses for the treatment of; The person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Fructus Aurantii 67g Semen Euphorbiae 67g Herba Melastomatis Dodecandri 67g Cuculus polioephalus 62g
Fructus Piperis Longi 62g Endoconcha Sepiae 62g coriander 60g Radix Gossampini 60g
Rhizoma Cyperi 60g Rhizoma Alpiniae Officinarum 58g Folium Callicarpae Formosanae 58g Coniogramme japonica (Thunb.) Diels 58g
Radix Hemsleyae Macrospermae 50g Rhizoma Corydalis 50g Semen Alpiniae Katsumadai 48g Concha Arcae 48g.
The present embodiment Chinese drugs agentia preparation method processing step and usage and dosage are identical with embodiment 1.
Embodiment 3
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Fructus Aurantii 60g Semen Euphorbiae 60g Herba Melastomatis Dodecandri 60g Cuculus polioephalus 56g
Fructus Piperis Longi 56g Endoconcha Sepiae 56g coriander 54g Radix Gossampini 54g
Rhizoma Cyperi 54g Rhizoma Alpiniae Officinarum 53g Folium Callicarpae Formosanae 53g Coniogramme japonica (Thunb.) Diels 53g
Radix Hemsleyae Macrospermae 45g Rhizoma Corydalis 45g Semen Alpiniae Katsumadai 43g Concha Arcae 43g.
The present embodiment Chinese drugs agentia preparation method processing step and usage and dosage are identical with embodiment 1.
Embodiment 4
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Fructus Aurantii 53g Semen Euphorbiae 53g Herba Melastomatis Dodecandri 53g Cuculus polioephalus 50g
Fructus Piperis Longi 50g Endoconcha Sepiae 50g coriander 47g Radix Gossampini 47g
Rhizoma Cyperi 47g Rhizoma Alpiniae Officinarum 45g Folium Callicarpae Formosanae 45g Coniogramme japonica (Thunb.) Diels 45g
Radix Hemsleyae Macrospermae 40g Rhizoma Corydalis 40g Semen Alpiniae Katsumadai 38g Concha Arcae 38g.
The present embodiment Chinese drugs agentia preparation method processing step and usage and dosage are identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of digestive tract hemorrhage, select Diagnosing Gastrointestinal Bleeding 360 examples to carry out clinical observation, patient is divided into two groups at random, treatment group 180 examples, male 92 examples wherein, women's 88 examples, age 25-60 year, 42.3 years old mean age, course of disease 1-3 month; Matched group 180 examples, male 90 examples wherein, women's 90 examples, age 26-60 year, 41.2 years old mean age, course of disease 1-3 month; Two groups of patient medical record are basically identical, without significant difference, have comparability, all keep on a diet on request for two groups.
2, medication is selected:
Treatment group person's trouble is taken Chinese medicine preparation of the present invention, and oral, each 2 every day 3 times, 5 days is a course for the treatment of, takes continuously 3 to 5 courses for the treatment of and can fully recover, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Matched group is taken stomach-recovering capsule, by specification use, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
3, curative effect judgement:
Cure: the symptom digestive tract hemorrhage transference cure such as spit blood, have blood in stool, digestive tract recovers normal function.
Take a turn for the better: above-mentioned symptom is alleviated to some extent.
Invalid: symptom is unchanged.
4, therapeutic outcome:
Treatment group: cure 123 examples, 50 examples that take a turn for the better, invalid 7 examples, cure rate is 68.3%, total effective rate is 96.1%.
Matched group: cure 75 examples, 53 examples that take a turn for the better, invalid 52 examples, cure rate is 41.7%, total effective rate is 71.1%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
5, model case is for example:
(1) connect certain, man, 56 years old, peasant, Hunan people from Ningxiang.Before patient is admitted to hospital, without obvious inducement, start to occur epigastrium pain, be paroxysmal dull pain, each approximately 10 minutes, without radiating pain, separate melena 1 time, amount is few, be about 100 grams, do not give attention, after again there is melena 3 times, amount is the same, and without fear of cold heating, random thoughts are felt sick, without vomiting, have dizziness headache, weak, the diagnosis and treatment of being admitted to hospital are upper gastrointestinal hemorrhage.Patient takes 2 courses for the treatment of of Chinese medicine preparation of the present invention, and conditions of patients obviously alleviates, and continues to take 2 courses for the treatment of, and conditions of patients recovery from illness, follows up a case by regular visits to and have no recurrence.
(2) Wei, female, 38 years old, is remembering Yinchuan of Ningxia Province people.Without obvious inducement, there is row's cerise hemafecia repeatedly in patient, the row gastroscope of being admitted to hospital prompting pyloric cap is to kiss ulcer, and the about 500ml of vomiting cerise gastric content, appears in the Lactoferrin 46g/l that has a blood test, containing food and sludged blood, companion row hemafecia, approximately 2000ml, accompanies dizzy, malaise, after give red cells transfusion 2 units, the Supporting Therapy (specifically not quite clear) of suiting the medicine to the illness, effect is not good enough.After rear doctor gives Chinese medicine preparation of the present invention and takes, taking a turn for the better appears in the second day state of an illness, takes after 4 courses for the treatment of, and patient returns to one's perfect health.
(3) in certain, man, 32 years old, workman, Shandong Zibo people.Patient, because diet causes diarrhoea stomachache accidentally, defecates rare, for kermesinus or black watery stool, weak with dizziness, after rest, has no and alleviates, and admission examination patient mind is clear, neurolysis, and cardiopulmonary are without extremely, and abdomen is soft without tenderness and rebound tenderness, 9 beats/min of borborygmus.Skin elasticity can, skin temperature is normal, routine blood test: HGB103g/l is remaining roughly normal, is digestive tract hemorrhage after diagnosing.Take Chinese medicine preparation of the present invention after 4 courses for the treatment of, conditions of patients recovery from illness, has no recurrence.

Claims (5)

1. a Chinese medicine preparation for the treatment of digestive tract hemorrhage, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Fructus Aurantii 46-74 part Semen Euphorbiae 46-74 part Herba Melastomatis Dodecandri 46-74 part Cuculus polioephalus 44-70 part
Fructus Piperis Longi 44-70 part Endoconcha Sepiae 44-70 part coriander 40-68 part Radix Gossampini 40-68 part
Rhizoma Cyperi 40-68 part Rhizoma Alpiniae Officinarum 38-65 part Folium Callicarpae Formosanae 38-65 part Coniogramme japonica (Thunb.) Diels 38-65 part
Radix Hemsleyae Macrospermae 35-60 part Rhizoma Corydalis 35-60 part Semen Alpiniae Katsumadai 33-55 part Concha Arcae 33-55 part.
2. a kind of Chinese medicine preparation for the treatment of digestive tract hemorrhage according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
62 parts of 67 portions of Cuculus polioephalus of 67 parts of Herba Melastomatis Dodecandri of 67 parts of Semen Euphorbiaes of Fructus Aurantii
60 parts of 60 parts of Radix Gossampinis of 62 parts of corianders of 62 portions of Endoconcha Sepiaes of Fructus Piperis Longi
58 parts of 58 parts of Coniogramme japonica (Thunb.) Dielss of 58 portions of Folium Callicarpae Formosanaes of 60 portions of Rhizoma Alpiniae Officinarums of Rhizoma Cyperi
48 parts of 48 parts of Concha Arcaes of 50 parts of Semen Alpiniae Katsumadai of 50 parts of Rhizoma Corydalis of Radix Hemsleyae Macrospermae.
3. a kind of Chinese medicine preparation for the treatment of digestive tract hemorrhage according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
56 parts of 60 portions of Cuculus polioephalus of 60 parts of Herba Melastomatis Dodecandri of 60 parts of Semen Euphorbiaes of Fructus Aurantii
54 parts of 54 parts of Radix Gossampinis of 56 parts of corianders of 56 portions of Endoconcha Sepiaes of Fructus Piperis Longi
53 parts of 53 parts of Coniogramme japonica (Thunb.) Dielss of 53 portions of Folium Callicarpae Formosanaes of 54 portions of Rhizoma Alpiniae Officinarums of Rhizoma Cyperi
43 parts of 43 parts of Concha Arcaes of 45 parts of Semen Alpiniae Katsumadai of 45 parts of Rhizoma Corydalis of Radix Hemsleyae Macrospermae.
4. a kind of Chinese medicine preparation for the treatment of digestive tract hemorrhage according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
50 parts of 53 portions of Cuculus polioephalus of 53 parts of Herba Melastomatis Dodecandri of 53 parts of Semen Euphorbiaes of Fructus Aurantii
47 parts of 47 parts of Radix Gossampinis of 50 parts of corianders of 50 portions of Endoconcha Sepiaes of Fructus Piperis Longi
45 parts of 45 parts of Coniogramme japonica (Thunb.) Dielss of 45 portions of Folium Callicarpae Formosanaes of 47 portions of Rhizoma Alpiniae Officinarums of Rhizoma Cyperi
38 parts of 38 parts of Concha Arcaes of 40 parts of Semen Alpiniae Katsumadai of 40 parts of Rhizoma Corydalis of Radix Hemsleyae Macrospermae.
5. as described in claim 1-4 any one, treat a preparation method for the Chinese medicine preparation of digestive tract hemorrhage, it is characterized in that: comprise following processing step:
(1) get Fructus Aurantii, Cuculus polioephalus, Rhizoma Alpiniae Officinarum, Rhizoma Corydalis and Semen Alpiniae Katsumadai decontamination, dry, be placed in mortar, grind into powder, cross 180 order fine powders, standby;
(2) get Semen Euphorbiae, Radix Gossampini and Folium Callicarpae Formosanae decontamination and clean, dry, add 80% alcoholic solution of 5 times of amounts, soak 2-4 hour, heating extraction 3 hours, reclaims ethanol, filters, and under 60 ℃ of environment of filtrate simmer down to, the thick paste of relative density 1.20~1.25, standby;
(3) get Herba Melastomatis Dodecandri, Fructus Piperis Longi, Endoconcha Sepiae, coriander, Rhizoma Cyperi, Coniogramme japonica (Thunb.) Diels, Radix Hemsleyae Macrospermae and Concha Arcae decontamination, clean and put into container, the distilled water that adds 8-12 doubly to measure, soaked after 4-5 hour, boiled 3-4 hour, extracted; Again add 6-8 doubly to measure distilled water, boil 2-3 hour, extract; Finally add 4-6 doubly to measure distilled water, heated and boiled 1-2 hour, extracts; Merge three times extracting solution, filter, reserved filtrate, standby;
(4) above-mentioned steps (1)-(3) prepared fine powder and thick paste are mixed, utilize modern advanced pharmacy science and technology, make capsule, be the Chinese medicine preparation of described treatment digestive tract hemorrhage.
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CN105456536A (en) * 2016-01-25 2016-04-06 闵卫 Drug for treating hematemesis

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CN1686308A (en) * 2005-03-21 2005-10-26 李丰中 Medicine for treating gastritis and gastrelcoma and its preparation method
CN1966036A (en) * 2006-11-25 2007-05-23 李勇奇 Chinese medicine for treating gastrointestinal disease and preparation method thereof
CN103083628A (en) * 2011-11-01 2013-05-08 焦国荣 Medicine composition for treating gastric and duodenal ulcer and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN1686308A (en) * 2005-03-21 2005-10-26 李丰中 Medicine for treating gastritis and gastrelcoma and its preparation method
CN1966036A (en) * 2006-11-25 2007-05-23 李勇奇 Chinese medicine for treating gastrointestinal disease and preparation method thereof
CN103083628A (en) * 2011-11-01 2013-05-08 焦国荣 Medicine composition for treating gastric and duodenal ulcer and preparation method thereof

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* Cited by examiner, † Cited by third party
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CN105456536A (en) * 2016-01-25 2016-04-06 闵卫 Drug for treating hematemesis

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