CN104524203A - Traditional Chinese medicine preparation for treating gastrointestinal hemorrhage and preparation method of traditional Chinese medicine preparation - Google Patents
Traditional Chinese medicine preparation for treating gastrointestinal hemorrhage and preparation method of traditional Chinese medicine preparation Download PDFInfo
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- CN104524203A CN104524203A CN201410757722.1A CN201410757722A CN104524203A CN 104524203 A CN104524203 A CN 104524203A CN 201410757722 A CN201410757722 A CN 201410757722A CN 104524203 A CN104524203 A CN 104524203A
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Abstract
The invention relates to a traditional Chinese medicine preparation and a preparation method thereof and particularly relates to a traditional Chinese medicine preparation for treating gastrointestinal hemorrhage and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from the following traditional Chinese medicine raw materials in parts by weight: 20-30 parts of bletilla striata, 20-30 parts of astragalus, 20-30 parts of coptis chinensis, 20-30 parts of salvia miltiorrhiza, 20-30 parts of rheum officinale, 15-20 parts of angelica sinensis, 15-20 parts of herba patriniae, 15-20 parts of radix dipsaci, 15-20 parts of rhizoma corydalis, 10-15 parts of polygonum cuspidatum, 5-10 parts of trogopterus dung, 10-15 parts of sanguisorba officinalis, 5-10 parts of green tangerine peel, 3-5 parts of immature bitter oranges, 3-5 parts of cyperus rotundus and 3-5 parts of panax pseudoginseng. The traditional Chinese medicine preparation has the advantage that the adopted traditional Chinese medicines conform to the regulation of the China Pharmacopoeia so as to be safe and reliable. All the traditional Chinese medicines are matched so as to achieve the effects of stopping bleeding and relieving pain, resisting to gastric ulcer and the like. The traditional Chinese medicine preparation has the characteristics of exact curative effect, high effect taking speed, high cure rate, no side effects and the like when being used for treating gastrointestinal hemorrhage.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, be specifically related to a kind of Chinese medicine preparation for the treatment of digestive tract hemorrhage and preparation method thereof.
Background technology
Digestive tract hemorrhage is common clinical, often because of comparatively urgency and diagnose and unclearly jeopardize patient vitals of falling ill.Digestive tract hemorrhage is divided into upper gastrointestinal hemorrhage and lower digestive tract hemorrhage usually.Upper gastrointestinal hemorrhage refers to that the digestive tract that petechia is positioned at more than Qu Shi ligament comprises the hemorrhage of the positions such as esophagus, stomach and duodenum.Lower digestive tract hemorrhage refers to the digestive tract hemorrhage occurring in below Qu Shi ligament, comprises small intestinal, coton and rectal.
The character of hemorrhage pathological changes, position, blood loss and speed are depended in the clinical manifestation of digestive tract hemorrhage, also have relation with the systemic conditions such as age, cardiorenal function of patient.
Cause hemorrhage, treatment for esophageal varices bleeding, avulsion mucous syndrome, vascular lesion and tumor etc. that the reason of upper gastrointestinal hemorrhage has esophagus, stomach and duodenal ulcer and mucosal erosion to cause usually.The diverticulitis of lower digestive tract intestinal, angiodysplasia, tumor account for, inflammation accounts for and optimum anorectal disease to cause the common cause of lower digestive tract hemorrhage to have.Acute majority of bleeding profusely shows as hematemesis, and chronic small amount bleeding is then with fecal occult blood positive performance.
For the patient of digestive tract hemorrhage, observation expression and limb skin are cold wet or warm, and recording blood pressure, pulse, amount of bleeding and urine volume per hour keep vein energy circuit also to measure central venous pressure.Keep patient respiration road unobstructed, avoid occurring surprisingly during hematemesis.
If a kind of medicine safely and effectively can be invented help patient treatment disease and will improve the therapeutic effect of digestive tract hemorrhage widely.
Summary of the invention
According to above the deficiencies in the prior art, the present invention proposes a kind of Chinese medicine preparation for the treatment of digestive tract hemorrhage and preparation method thereof, and it is evident in efficacy, safe and reliable, have no side effect, and has wide potential applicability in clinical practice.
A kind of Chinese medicine preparation for the treatment of digestive tract hemorrhage of the present invention, according to weight parts, be prepared from by following raw material of Chinese medicine: the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 ~ 30 parts, the Radix Astragali 20 ~ 30 parts, Rhizoma Coptidis 20 ~ 30 parts, Radix Salviae Miltiorrhizae 20 ~ 30 parts, Radix Et Rhizoma Rhei 20 ~ 30 parts, Radix Angelicae Sinensis 15 ~ 20 parts, Herba Patriniae 15 ~ 20 parts, Radix Dipsaci 15 ~ 20 parts, Rhizoma Corydalis 15 ~ 20 parts, Rhizoma Polygoni Cuspidati 10 ~ 15 parts, Oletum Trogopterori 5 ~ 10 parts, Radix Sanguisorbae 10 ~ 15 parts, 5 ~ 10 parts, Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus 3 ~ 5 parts, Rhizoma Cyperi 3 ~ 5 parts and Radix Notoginseng 3 ~ 5 parts.
Wherein, preferred version is as follows:
According to weight parts, be prepared from by following raw material of Chinese medicine: the Pseudobulbus Bletillae (Rhizoma Bletillae) 25 parts, the Radix Astragali 25 parts, Rhizoma Coptidis 25 parts, Radix Salviae Miltiorrhizae 25 parts, Radix Et Rhizoma Rhei 25 parts, Radix Angelicae Sinensis 18 parts, Herba Patriniae 18 parts, Radix Dipsaci 18 parts, Rhizoma Corydalis 18 parts, Rhizoma Polygoni Cuspidati 12 parts, Oletum Trogopterori 8 parts, Radix Sanguisorbae 12 parts, 8 parts, Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus 4 parts, Rhizoma Cyperi 4 parts and Radix Notoginseng 4 parts.
A kind of preparation method for the treatment of the Chinese medicine preparation of digestive tract hemorrhage of the present invention, prepare in accordance with the following methods: take raw material of Chinese medicine according to formula and join in container, add water and cover powder immersion 10 ~ 20 minutes, add water again and do not have powder 3 ~ 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 ~ 30 minutes to boiling, get filtrate; And then add water and do not have powder 3 ~ 5 centimetres, decoct with high heat and uses slow fire boiling again instead 15 ~ 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
When taking, each 300ml, one day twice.
Pharmacology analysis:
The Pseudobulbus Bletillae (Rhizoma Bletillae): bitter, sweet, puckery, is slightly cold.Return lung, liver, stomach warp.Astringing to arrest bleeding, detumescence and promoting granulation.Cure mainly interior traumatic hemorrhage, spit blood for hemoptysis, traumatic hemorrhage, sore swollen toxin, chapped skin; Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
The Radix Astragali: sweet, tepor.Return lung, spleen, liver, kidney channel.Invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, diuresis, granulation promoting., chronic diarrhea proctoptosis, spontaneous perspiration, edema weak for the deficiency of vital energy, sub-official prolapsus, chronic nephritis proteinuria, diabetes, open sore part disunion of a specified duration.
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
Radix Salviae Miltiorrhizae: bitter, is slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Radix Et Rhizoma Rhei: bitter, cold.Return spleen, stomach, large intestine, liver, pericardium channel.Purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.
Radix Angelicae Sinensis: sweet in the mouth, temperature.Return liver, the heart, spleen channel.Enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.The all cards of main blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Herba Patriniae: pungent, bitter, cool.Enter stomach, large intestine, Liver Channel.Heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood circulation promoting competent silt.For acute appendicitis, lung abscess and sore and toxic, the stagnant caused breast abdomen pain of the excess-heat stasis of blood, the diseases such as the stagnant stomachache of the stasis of blood in puerperal.
Radix Dipsaci: bitter, pungent, tepor.Enter liver, kidney channel.Invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating.Control aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer swells.
Rhizoma Corydalis: pungent, bitter, temperature.Return liver, spleen channel.Invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
Rhizoma Polygoni Cuspidati: micro-hardship, is slightly cold.Return liver, gallbladder, lung meridian.Expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea, lump in the abdomen, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus, cough with copious phlegm.
Oletum Trogopterori: bitter sweet, temperature.Enter liver, spleen channel.Promoting the circulation of blood pain relieving is used in life.Control all pains of trusted subordinate's vim and vigour, women's amenorrhea, postnatal blood stasis is had a pain; External treatment Serpentis, scorpion, centipete bite.Stir-fry is stopped blooding.Control metrorrhagia, menorrhagia, leucorrhea with bloody discharge is without cease.
Radix Sanguisorbae: bitter, sour, puckery, is slightly cold.Enter liver, large intestine channel.Blood on removing heat from blood, heat-clearing and toxic substances removing.Control haematemesis, epistaxis, dysentery, metrorrhagia, hemorrhoidal hamorrhage, anal fistula, carbuncle, eczema, incised wound, burn.
Pericarpium Citri Reticulatae Viride: bitter, pungent, temperature.Return liver, gallbladder, stomach warp.Soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.For distending pain in the chest and hypochondrium, hernia, nodule in the breast, acute mastitis, abdominal pain due to retention of food.
Fructus Aurantii Immaturus: bitter; Pungent; Cold.Return spleen; Stomach; Liver; Heart channel.Effect: stop in stagnant; Feeling of fullness distending pain; Constipation; Heavy after dysentery; Blocked-up chest; Gastroptosis; Uterine prolapse; Proctoptosis.
Rhizoma Cyperi: pungent, micro-hardship, micro-sweet is flat.Return liver, spleen, tri-jiao channel.Promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Radix Notoginseng: be mainly distributed in the ground such as Yunnan, Guangxi, Jiangxi, Sichuan.Radix Notoginseng is used as medicine with its root, and it is warm in nature, acrid in the mouth, has significant blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain effect, has the good reputation of " Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) ", " southern part of the country SHENCAO ".Excavating in season in winter in spring two because being everlasting, being divided into again " spring seven " and " winter seven ".Because Radix Notoginseng is all panax species, and its effective active matter higher than with more than Radix Ginseng, be therefore called " king in ginseng " by modern Chinese medicine medicine scholar again.Record in Qing Dynasty's pharmaceutical texts supplementary Amplifications of the Compendium of Materia Medica: " ginseng qi-tonifying the first, Radix Notoginseng enriches blood the first, taste with and merit also etc., therefore claiming Panax pseudoginseng, is the most precious person in Chinese medicine." become famous Chinese patent medicine " YUNNAN BAIYAO " at home and abroad and " Pien Tze Huang ", be namely that primary raw material is made with Radix Notoginseng.Cure mainly spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
The invention has the advantages that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.All medicine phases and have hemostasis and pain-relieving, the effects such as anti-gastric-ulcer, treatment digestive tract hemorrhage has that determined curative effect, instant effect, cure rate are high, the feature such as have no side effect.
Outcome measure:
1, case selection:
As the Chinese medicine preparation for the treatment of digestive tract hemorrhage, select Diagnosing Gastrointestinal Bleeding 180 example to carry out clinical observation, wherein man 92 example, women 88 example, age 25-60 year, 42.3 years old mean age, course of disease 1-3 month.Take Chinese medicine preparation of the present invention, oral, each 300ml, every day 2 times 5 days is a course for the treatment of, and taking 3 to 5 courses for the treatment of continuously can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
2, criterion of therapeutical effect:
Cure: the symptom digestive tract hemorrhage transference cure such as to spit blood, have blood in stool, digestive tract recovers normal function.
Take a turn for the better: above-mentioned symptom is alleviated to some extent.
Invalid: symptom is unchanged.
3, therapeutic outcome: cure 123 examples, take a turn for the better 50 examples, and invalid 7 examples, cure rate is 68.3%, and total effective rate is 96.1%.
4, model case citing:
(1) Xing, man, 56 years old, peasant, people from Qingdao.Start to occur epigastrium pain without obvious inducement before patient admits, in paroxysmal dull pain, about 10 minutes at every turn, without radiating pain, separate melena 1 time, amount is few, be about 100 grams, do not give attention, after again there is melena 3 times, amount is the same, and without fear of cold heating, random thoughts are felt sick, without vomiting, have dizziness headache, weak, diagnosis and treatment of being admitted to hospital are upper gastrointestinal hemorrhage.Patient takes 2 courses for the treatment of of Chinese medicine preparation of the present invention, and conditions of patients obviously alleviates, and continues to take 2 courses for the treatment of, and conditions of patients is fully recovered, and follows up a case by regular visits to and has no recurrence.
(2) Wei, female, 44 years old, reporter, people from Qingdao.Row's cerise hemafecia is there is repeatedly in patient without obvious inducement, row gastroscope of being admitted to hospital prompting pyloric cap is to kiss property ulcer, and have a blood test Lactoferrin 46g/l, occurs that vomiting cerise gastric content is about 500ml, containing food and sludged blood, companion row hemafecia, about 2000ml, companion is dizzy, malaise, after give red cells transfusion 2 unit, suit the medicine to the illness Supporting Therapy (specifically not quite clear), less effective.Rear doctor gives after Chinese medicine preparation of the present invention takes, and taking a turn for the better appears in second day state of an illness, and after taking 4 courses for the treatment of, patient returns to one's perfect health.
Detailed description of the invention
The present invention will be further described by the following examples.
Embodiment 1:
A kind of Chinese medicine preparation for the treatment of digestive tract hemorrhage, according to weight parts, be prepared from by following raw material of Chinese medicine: the Pseudobulbus Bletillae (Rhizoma Bletillae) 25 parts, the Radix Astragali 25 parts, Rhizoma Coptidis 25 parts, Radix Salviae Miltiorrhizae 25 parts, Radix Et Rhizoma Rhei 25 parts, Radix Angelicae Sinensis 18 parts, Herba Patriniae 18 parts, Radix Dipsaci 18 parts, Rhizoma Corydalis 18 parts, Rhizoma Polygoni Cuspidati 12 parts, Oletum Trogopterori 8 parts, Radix Sanguisorbae 12 parts, 8 parts, Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus 4 parts, Rhizoma Cyperi 4 parts and Radix Notoginseng 4 parts.
Embodiment 2:
According to the formula of embodiment 1, the Chinese medicine preparation of preparation treatment digestive tract hemorrhage in accordance with the following methods: take raw material of Chinese medicine according to formula and join in container, add water and cover powder and soak 20 minutes, add water again and do not have powder 5 centimetres, decoct with high heat and use slow fire boiling again instead 30 minutes to boiling, get filtrate; And then add water and do not have powder 5 centimetres, decoct with high heat and uses slow fire boiling again instead 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
When taking, each 300ml, one day twice.
Claims (3)
1. treat the Chinese medicine preparation of digestive tract hemorrhage for one kind, it is characterized in that according to weight parts, be prepared from by following raw material of Chinese medicine: the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 ~ 30 parts, the Radix Astragali 20 ~ 30 parts, Rhizoma Coptidis 20 ~ 30 parts, Radix Salviae Miltiorrhizae 20 ~ 30 parts, Radix Et Rhizoma Rhei 20 ~ 30 parts, Radix Angelicae Sinensis 15 ~ 20 parts, Herba Patriniae 15 ~ 20 parts, Radix Dipsaci 15 ~ 20 parts, Rhizoma Corydalis 15 ~ 20 parts, Rhizoma Polygoni Cuspidati 10 ~ 15 parts, Oletum Trogopterori 5 ~ 10 parts, Radix Sanguisorbae 10 ~ 15 parts, 5 ~ 10 parts, Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus 3 ~ 5 parts, Rhizoma Cyperi 3 ~ 5 parts and Radix Notoginseng 3 ~ 5 parts.
2. a kind of Chinese medicine preparation for the treatment of digestive tract hemorrhage according to claim 1, it is characterized in that according to weight parts, be prepared from by following raw material of Chinese medicine: the Pseudobulbus Bletillae (Rhizoma Bletillae) 25 parts, the Radix Astragali 25 parts, Rhizoma Coptidis 25 parts, Radix Salviae Miltiorrhizae 25 parts, Radix Et Rhizoma Rhei 25 parts, Radix Angelicae Sinensis 18 parts, Herba Patriniae 18 parts, Radix Dipsaci 18 parts, Rhizoma Corydalis 18 parts, Rhizoma Polygoni Cuspidati 12 parts, Oletum Trogopterori 8 parts, Radix Sanguisorbae 12 parts, 8 parts, Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus 4 parts, Rhizoma Cyperi 4 parts and Radix Notoginseng 4 parts.
3. the preparation method of the Chinese medicine preparation of a treatment digestive tract hemorrhage according to claim 1, it is characterized in that preparing in accordance with the following methods: take raw material of Chinese medicine according to formula and join in container, add water and cover powder immersion 10 ~ 20 minutes, add water again and do not have powder 3 ~ 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 ~ 30 minutes to boiling, get filtrate; And then add water and do not have powder 3 ~ 5 centimetres, decoct with high heat and uses slow fire boiling again instead 15 ~ 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105031388A (en) * | 2015-09-15 | 2015-11-11 | 徐玉田 | Medicine for treating alimentary tract hemorrhage and preparing method |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101940720A (en) * | 2010-09-10 | 2011-01-12 | 重庆市南川区金佛山中药材品种培育研究所 | Traditional Chinese herbal medicine for treating peptic ulcer (blood stasis obstructing the collaterals) |
| CN104027752A (en) * | 2013-03-05 | 2014-09-10 | 范德润 | Traditional Chinese medicine preparation for treating upper gastrointestinal hemorrhage |
| CN104069360A (en) * | 2014-06-30 | 2014-10-01 | 咸洪震 | Traditional Chinese medicinal preparation for treating gastrointestinal hemorrhage and preparation method thereof |
-
2014
- 2014-12-10 CN CN201410757722.1A patent/CN104524203A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101940720A (en) * | 2010-09-10 | 2011-01-12 | 重庆市南川区金佛山中药材品种培育研究所 | Traditional Chinese herbal medicine for treating peptic ulcer (blood stasis obstructing the collaterals) |
| CN104027752A (en) * | 2013-03-05 | 2014-09-10 | 范德润 | Traditional Chinese medicine preparation for treating upper gastrointestinal hemorrhage |
| CN104069360A (en) * | 2014-06-30 | 2014-10-01 | 咸洪震 | Traditional Chinese medicinal preparation for treating gastrointestinal hemorrhage and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105031388A (en) * | 2015-09-15 | 2015-11-11 | 徐玉田 | Medicine for treating alimentary tract hemorrhage and preparing method |
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Application publication date: 20150422 |