CN103712125A - 光源模块以及分析样品的分析仪器 - Google Patents

光源模块以及分析样品的分析仪器 Download PDF

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Publication number
CN103712125A
CN103712125A CN201310454368.0A CN201310454368A CN103712125A CN 103712125 A CN103712125 A CN 103712125A CN 201310454368 A CN201310454368 A CN 201310454368A CN 103712125 A CN103712125 A CN 103712125A
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CN
China
Prior art keywords
light
light source
source module
led
analytical instrument
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201310454368.0A
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English (en)
Chinese (zh)
Inventor
F.德雷尔
A.弗兰
J.维茨雷克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Priority to CN201711038060.2A priority Critical patent/CN107883204A/zh
Publication of CN103712125A publication Critical patent/CN103712125A/zh
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F21LIGHTING
    • F21KNON-ELECTRIC LIGHT SOURCES USING LUMINESCENCE; LIGHT SOURCES USING ELECTROCHEMILUMINESCENCE; LIGHT SOURCES USING CHARGES OF COMBUSTIBLE MATERIAL; LIGHT SOURCES USING SEMICONDUCTOR DEVICES AS LIGHT-GENERATING ELEMENTS; LIGHT SOURCES NOT OTHERWISE PROVIDED FOR
    • F21K9/00Light sources using semiconductor devices as light-generating elements, e.g. using light-emitting diodes [LED] or lasers
    • F21K9/20Light sources comprising attachment means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F21LIGHTING
    • F21KNON-ELECTRIC LIGHT SOURCES USING LUMINESCENCE; LIGHT SOURCES USING ELECTROCHEMILUMINESCENCE; LIGHT SOURCES USING CHARGES OF COMBUSTIBLE MATERIAL; LIGHT SOURCES USING SEMICONDUCTOR DEVICES AS LIGHT-GENERATING ELEMENTS; LIGHT SOURCES NOT OTHERWISE PROVIDED FOR
    • F21K9/00Light sources using semiconductor devices as light-generating elements, e.g. using light-emitting diodes [LED] or lasers
    • F21K9/60Optical arrangements integrated in the light source, e.g. for improving the colour rendering index or the light extraction
    • F21K9/61Optical arrangements integrated in the light source, e.g. for improving the colour rendering index or the light extraction using light guides
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F21LIGHTING
    • F21VFUNCTIONAL FEATURES OR DETAILS OF LIGHTING DEVICES OR SYSTEMS THEREOF; STRUCTURAL COMBINATIONS OF LIGHTING DEVICES WITH OTHER ARTICLES, NOT OTHERWISE PROVIDED FOR
    • F21V23/00Arrangement of electric circuit elements in or on lighting devices
    • F21V23/003Arrangement of electric circuit elements in or on lighting devices the elements being electronics drivers or controllers for operating the light source, e.g. for a LED array
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F21LIGHTING
    • F21YINDEXING SCHEME ASSOCIATED WITH SUBCLASSES F21K, F21L, F21S and F21V, RELATING TO THE FORM OR THE KIND OF THE LIGHT SOURCES OR OF THE COLOUR OF THE LIGHT EMITTED
    • F21Y2115/00Light-generating elements of semiconductor light sources
    • F21Y2115/10Light-emitting diodes [LED]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N2021/0106General arrangement of respective parts
    • G01N2021/015Apparatus with interchangeable optical heads or interchangeable block of optics and detector
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N2021/6417Spectrofluorimetric devices
    • G01N2021/6419Excitation at two or more wavelengths
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/02Mechanical
    • G01N2201/024Modular construction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/062LED's
    • G01N2201/0627Use of several LED's for spectral resolution
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/08Optical fibres; light guides
    • G01N2201/0806Light rod

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN201310454368.0A 2012-10-01 2013-09-29 光源模块以及分析样品的分析仪器 Pending CN103712125A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711038060.2A CN107883204A (zh) 2012-10-01 2013-09-29 光源模块以及分析样品的分析仪器

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12186864.0 2012-10-01
EP12186864.0A EP2713154B1 (en) 2012-10-01 2012-10-01 Light source module and method for modifying an analytical instrument for analyzing a sample

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201711038060.2A Division CN107883204A (zh) 2012-10-01 2013-09-29 光源模块以及分析样品的分析仪器

Publications (1)

Publication Number Publication Date
CN103712125A true CN103712125A (zh) 2014-04-09

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CN201310454368.0A Pending CN103712125A (zh) 2012-10-01 2013-09-29 光源模块以及分析样品的分析仪器
CN201711038060.2A Pending CN107883204A (zh) 2012-10-01 2013-09-29 光源模块以及分析样品的分析仪器

Family Applications After (1)

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Country Status (5)

Country Link
US (2) US20140093948A1 (https=)
EP (1) EP2713154B1 (https=)
JP (1) JP6210813B2 (https=)
CN (2) CN103712125A (https=)
ES (1) ES2776481T3 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
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CN106442439A (zh) * 2016-08-31 2017-02-22 马东阁 一种oled膀胱检测设备及方法
CN106442489A (zh) * 2016-08-31 2017-02-22 马东阁 一种oled尿液分析设备
CN109358000A (zh) * 2018-10-23 2019-02-19 福建信息职业技术学院 一种双驼峰型光谱的发光装置及输出多种单色光的方法
CN110132931A (zh) * 2019-06-17 2019-08-16 北京百康芯生物科技有限公司 导光棒传光无透镜照明成像装置及微流控芯片检测系统

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EP3208604B1 (en) 2016-02-22 2019-07-10 F. Hoffmann-La Roche AG Optics for analysis of microwells
MX391374B (es) 2016-05-11 2025-03-21 Nova Biomedical Corp Sensor so2 de sangre entera.
CN107005656B (zh) * 2016-05-30 2019-12-27 深圳市大疆创新科技有限公司 可移动设备及其控制方法和装置、控制终端及拍摄设备
CN109478782B (zh) * 2016-07-21 2023-08-29 西门子医疗保健诊断公司 用于模块化ivd分析器容器推进器子系统的冗余功率管理
US10295136B2 (en) * 2016-11-07 2019-05-21 Lumileds Llc Light emission assembly with beam shaping structure
EP3336495B1 (en) * 2016-12-16 2024-02-14 F. Hoffmann-La Roche AG Characterizing the emission properties of samples
US10386232B2 (en) 2017-12-15 2019-08-20 Horiba Instruments Incorporated Compact spectroscopic optical instrument
CN109406454B (zh) * 2018-09-11 2021-01-15 江苏大学 一种改进的z扫描装置
US12228743B2 (en) * 2019-02-13 2025-02-18 Uniogen Oy Test strip reader device and a method for detecting a test result
CN111024137B (zh) * 2019-12-27 2021-07-16 中国科学院长春光学精密机械与物理研究所 一种线性测量系统
GB202010028D0 (en) * 2020-06-30 2020-08-12 Ams Int Ag Apparatus for determining the presence or concentration of target molecules
JP7605962B2 (ja) * 2020-08-05 2024-12-24 ライカ マイクロシステムズ シーエムエス ゲゼルシャフト ミット ベシュレンクテル ハフツング 蛍光顕微鏡における照明調整方法および対応する蛍光顕微鏡
EP4092466A1 (en) * 2021-05-21 2022-11-23 Leica Microsystems CMS GmbH Method for obtaining an operating value of an illumination parameter for examining a fluorescent sample, method for examining a fluorescent sample, microscope system and computer program
WO2025175014A1 (en) * 2024-02-15 2025-08-21 Roche Sequencing Solutions, Inc. Techniques for synthesizing a macromolecule from a sample

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WO2009001390A1 (en) * 2007-06-28 2008-12-31 Gian Luca Ferri Adjustable multi-band excitation and visualization / imaging system for simultaneous viewing multiple fluorescence
WO2010134104A1 (en) * 2009-05-20 2010-11-25 Universita' Degli Studi Di Cagliari Modular multi-band fluorescence excitation system.

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US20070183931A1 (en) * 2006-02-08 2007-08-09 Stock Daniel M Multimode reader
WO2009001390A1 (en) * 2007-06-28 2008-12-31 Gian Luca Ferri Adjustable multi-band excitation and visualization / imaging system for simultaneous viewing multiple fluorescence
WO2010134104A1 (en) * 2009-05-20 2010-11-25 Universita' Degli Studi Di Cagliari Modular multi-band fluorescence excitation system.

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106442439A (zh) * 2016-08-31 2017-02-22 马东阁 一种oled膀胱检测设备及方法
CN106442489A (zh) * 2016-08-31 2017-02-22 马东阁 一种oled尿液分析设备
CN109358000A (zh) * 2018-10-23 2019-02-19 福建信息职业技术学院 一种双驼峰型光谱的发光装置及输出多种单色光的方法
CN110132931A (zh) * 2019-06-17 2019-08-16 北京百康芯生物科技有限公司 导光棒传光无透镜照明成像装置及微流控芯片检测系统
CN110132931B (zh) * 2019-06-17 2024-08-20 北京百康芯生物科技有限公司 导光棒传光无透镜照明成像装置及微流控芯片检测系统

Also Published As

Publication number Publication date
EP2713154A1 (en) 2014-04-02
EP2713154B1 (en) 2020-01-08
JP2014089180A (ja) 2014-05-15
US20140093948A1 (en) 2014-04-03
CN107883204A (zh) 2018-04-06
US20200056985A1 (en) 2020-02-20
ES2776481T3 (es) 2020-07-30
JP6210813B2 (ja) 2017-10-11

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Application publication date: 20140409