CN103690889A - Traditional Chinese medicine decoction for treating stomach cancer - Google Patents
Traditional Chinese medicine decoction for treating stomach cancer Download PDFInfo
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- CN103690889A CN103690889A CN201310705970.7A CN201310705970A CN103690889A CN 103690889 A CN103690889 A CN 103690889A CN 201310705970 A CN201310705970 A CN 201310705970A CN 103690889 A CN103690889 A CN 103690889A
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Abstract
The invention discloses traditional Chinese medicine decoction for treating stomach cancer, belonging to the field of traditional Chinese medicines. The traditional Chinese medicine decoction for treating stomach cancer is prepared from the following bulk drugs by weight: 10 g of frankincense, 10 g of cinnamon, 15 g of selfheal, 15 g of agilawood, 15 g of radix ophiopogonis, 15 g of curcuma zedoary, 15 g of myrrh, 15 g of astragalus membranaceus, 15 g of the root of red-rooted salvia, 15 g of glossy privet fruit, 15 g of schisandra chinensis, 15 g of Chinese angelica, 15 g of root of common peony, 15 g of the rhizome of chuanxiong, 10 g of corydalis tuber, 10 g of rehmannia, 10 g of lucid ganoderma, 10 g of oldenlandia diffusa, 10 g of radix polygonati officinalis, 10 g of moutan bark, 10 g of edible tulip, 10 g of immature bitter orange, 10 g of lithospermum, and 5 g of musk. The traditional Chinese medicine decoction for treating stomach cancer has the effects of supporting body resistance, reinforcing qi, nourishing blood, promoting circulation, removing stasis, clearing heat and removing toxicity and is capable of effectively controlling metastasis of primary lesion and continuous diffusion of metastatic lesion and obviously relieving stomach cancer clinical symptoms; the traditional Chinese medicine decoction for treating stomach cancer has obvious curative effect on treatment of stomach cancer.
Description
Technical field
The present invention relates to a kind of Chinese medicine decoction for the treatment of gastric cancer, belong to technical field of Chinese medicines.
Background technology
Gastric cancer is the malignant tumor that is derived from gastric epithelial cell, the first place that occupies all kinds of tumors at its sickness rate of China, approximately there are every year 170000 people to die from gastric cancer, almost approach 1/4 of whole mortality of malignant tumors numbers, the early stage normal non-evident sympton of gastric cancer, after progress that sb.'s illness took a turn for the worse, can engender epigastrium feeling of repletion, sense of heaviness, anorexia, stomachache, nausea,vomiting,diarrhea, become thin, anemia, edema, heating etc., cancerous protuberance diffusion transfer can cause the transfer of ascites, hepatomegaly, jaundice and lung, brain, the heart, prostate, ovary, bone marrow etc. and occur corresponding symptom.The generation of gastric cancer is mainly that food is relevant with dietary, also relevant with the factor such as heredity, body constitution.
Doctor trained in Western medicine has operative treatment, radiotherapy, medicine chemotherapy, immunization therapy etc. to gastric cancer conventional therapy at present, and above Therapeutic Method can only temporarily be controlled the state of an illness, can cause the sequela such as intraperitoneal pus infections or extensive adhesion after some operation in patients, and patient's prognosis effect is not good enough.Chinese traditional treatment gastric cancer is occupied critical role in curing gastric cancer, but existing treatment by Chinese herbs effect is obvious not, takes effect slower, to such an extent as to a large amount of patients received treatment of Chinese herbs on one side, on one side cancer metastasis diffusion, greatly shortened patient's life time.
Summary of the invention
The present invention has overcome above-mentioned the deficiencies in the prior art, and a kind of hypertensive Chinese medicine composition for the treatment of is provided, can benefiting QI for activating blood circulation, nourishing yin and dispelling wind-evil, improve the adverse effect that primary disease brings patient.
Technical scheme of the present invention is: a kind of Chinese medicine decoction for the treatment of gastric cancer, it is characterized in that, by the crude drug of following weight, made: 10 grams of Olibanums, 10 grams of Cortex Cinnamomis, 15 grams of Spica Prunellaes, 15 grams of Lignum Aquilariae Resinatum, 15 grams of Radix Ophiopogonis, 15 grams of Rhizoma Curcumae, 15 grams of Myrrhas, 15 grams of the Radixs Astragali, 15 grams of Radix Salviae Miltiorrhizaes, 15 grams of Fructus Ligustri Lucidi, 15 grams of Fructus Schisandrae Chinensis, 15 grams of Radix Angelicae Sinensis, 15 grams of Radix Paeoniae Rubra, 15 grams of Rhizoma Chuanxiongs, 10 grams of Rhizoma Corydalis, 10 grams of Radix Rehmanniae, 10 grams of Ganodermas, 10 grams of Herba Hedyotidis Diffusaes, 10 grams of Rhizoma Polygonati Odorati, 10 grams of Cortex Moutans, 10 grams of Pseudobulbus Cremastrae Seu Pleioness, 10 grams of Fructus Aurantii Immaturuss, 10 grams of Radix Arnebiae (Radix Lithospermi)s, 5 grams, Moschus.
Preparation and instructions of taking: first above-mentioned raw materials is soaked in water 2 hours, decocting in water 30 minutes, pours out medicinal liquid; Add again decocting in water 30 minutes, pour out medicinal liquid; Twice medicinal liquid amalgamation rises, and cools completely, and respectively at half an hour before breakfast, within after supper two hours, takes.Serveing on 20 days is a course for the treatment of.
The pharmacological action of each Chinese medicine:
Olibanum: regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Cortex Cinnamomi: complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation.Control decline of the fire from the gate of life, cold extremities faint pulse, YANG-depletion collapse, stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea and mass in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower.
Spica Prunellae: pungent, bitter, cold.Return liver, gallbladder meridian.Function with cure mainly: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, and goiter, acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Lignum Aquilariae Resinatum: arduous, temperature.Enter kidney, spleen, stomach warp.Sending down the abnormal ascending QI warming middle-JIAO, warming the kidney improving inspiration by invigorating kidney-QI.Control QI rising in reverse order and pant, vomiting singultus, abdominal distention, waist knee joint cold caused by deficiency, large intestine constipation due to insufficiency, urine qi stranguria, man's cold sperm.
Radix Ophiopogonis: sweet, micro-hardship, is slightly cold.GUIXIN, lung, stomach warp.YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria.
Rhizoma Curcumae: toil, temperature.Enter liver, spleen channel.Removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.For abdominal pain due to blood stasis, hepatosplenomegaly, trusted subordinate's distending pain, gather women's blood stasis amenorrhea, the traumatic injury eating accumulation of having a pain.
Myrrha: hardship, pungent, flat, nontoxic.Liver, spleen, the heart, kidney channel.The analgesic therapy of invigorating blood circulation, detumescence and promoting granulation, cures mainly traumatic injury, incised wound, muscles and bones, all pains of trusted subordinate, lump in the abdomen, amenorrhea, ulcer sore pain, skin infection does not close up after bursting for a long time.
The Radix Astragali: sweet, temperature.Return lung, spleen channel.Function with cure mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Radix Salviae Miltiorrhizae: hardship, is slightly cold.GUIXIN, Liver Channel.Function with cure mainly: blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, the relieving restlessness that clears away heart-fire, removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, and dysphoria and insomnia, menoxenia, dysmenorrhea amenorrhea, skin infection swells and ache.
Fructus Ligustri Lucidi: sweet, bitter, cold.Return liver, kidney channel.Nourishing the liver and kidney, improving eyesight black hair.For the hepatic and renal YIN deficiency, vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision, interior-heat is quenched one's thirst, osteopyrexia and fever.
Fructus Schisandrae Chinensis: sour, sweet, temperature.Lung, the heart, kidney channel.Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, palpitation and insomnia.
Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.
Radix Paeoniae Rubra: hardship, is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.For heat, enter nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, mass in the abdomen stomachache, injury from falling down, carbuncle skin infection etc.
Rhizoma Chuanxiong: acrid in the mouth, temperature.Enter liver, gallbladder meridian.Activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Control air-cooled headache revolve dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Rhizoma Corydalis: arduous, temperature.Enter liver, stomach warp.Invigorate blood circulation, dissipating blood stasis, regulates the flow of vital energy, pain relieving.Control all pains of trusted subordinate's waist knee joint, menoxenia ， mass in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.
Radix Rehmanniae: sweet, tepor.Return liver, kidney channel.Function with cure mainly: the YIN nourishing of enriching blood, beneficial essence is filled out marrow.For blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat seminal emission, interior-heat is quenched one's thirst, dizzy, tinnitus, early whitening of beard and hair.
Ganoderma: sweet, flat.GUIXIN, lung, liver, kidney channel.There is the effect of antitumor and protecting liver and detoxication.
Herba Hedyotidis Diffusae: bitter sweet, cold.Nontoxic, enter heart channel, Liver Channel, spleen channel.Effect: heat-clearing and toxic substances removing; Dampness removing.Cure mainly: dyspnea and cough due to lung-heat; Laryngopharynx swelling and pain; Intestinal carbuncle; Furuncle and phyma skin infection; Venom; The puckery pain of pyretic stranguria; Edema; Dysentery; Intestinal is scorching; Jaundice due to damp-heat; Be good at treatment kinds cancer.
Rhizoma Polygonati Odorati: sweet, be slightly cold.Attach to the lung and stomach meridians.Function with cure mainly: nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.For lung stomach-Yin wound, cough caused by dryness-heat, dry throat and mouth, interior-heat is quenched one's thirst.
Cortex Moutan: bitter in the mouth, pungent, cold nature, GUIXIN, liver, kidney channel.The merit with clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.Modern study shows, the effect that Cortex Moutan has antiinflammatory, analgesia, stops blooding, protects the liver.
Pseudobulbus Cremastrae Seu Pleiones: sweet, micro-pungent, cold.Enter liver, spleen channel.Detumescence, eliminating stagnation, reduces phlegm, removing toxic substances.Control carbuncle furuncle swollen, scrofula, sore throat swells and ache, Serpentis, worm, mad dog wound.
Fructus Aurantii Immaturus: bitter, pungent, sour, be slightly cold.Return spleen, stomach warp.Function with cure mainly: dispelling the stagnated QI removing food stagnancy, the loose painful abdominal mass of reducing phlegm.In stagnant, stop, feeling of fullness distending pain, heavy after dysentery, constipation, the stagnant vapour lock of expectorant, the thoracic obstruction, blocked-up chest, visceroptosis.
Radix Arnebiae (Radix Lithospermi): sweet, salty, cold.GUIXIN, Liver Channel.Function with cure mainly: removing heat from blood, invigorate blood circulation, removing toxic substances rash.For heat in blood poison, contain, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.
Moschus: pungent, temperature.Enter the heart, spleen, Liver Channel.Have one's ideas straightened out, ward off dirty, dredging collateral, dissipating blood stasis.Control apoplexy, syncope due to accumulation of phlegm, infantile convulsion, attacked by pestiferous factors is unhappy, trusted subordinate's sudden pain ， mass in the abdomen hypochondriac lump, traumatic injury, swollen ulcer drug.
The present invention is by after above drug regimen; drug effect has synergism, plays the effect of the body resistance strengthening and constitution consolidating, benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, effectively controls the transfer of primary lesion and the continuation of metastatic lesion diffusion; obviously alleviate gastric cancer clinical symptoms, the protection heart, liver, renal function.Be applied to can effectively control in the treatment of gastric cancer patient's self health, treatment gastric cancer is evident in efficacy.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
One, clinical observation
1, clinical data: be selected from the outpatient service in December, 2011 to 2013 year March and inpatient totally 138 examples, wherein early gastric cancer 49 examples.Age is 37-72 year, average 57.5 years old.
2, diagnostic criteria: be foundation to the regulation of the precancerous lesion of gastric cancer in the < < China common cancer diagnosis and treatment standard > > (the 4th gastric cancer) that publish nineteen ninety according to China.
3, Therapeutic Method: take medicine of the present invention, decocting boils, takes at twice sooner or later.It within 1 month, is 1 course for the treatment of.
4, efficacy assessment standard: the standard according to Ministry of Public Health version < < China common cancer diagnosis and treatment standard > > in 1991 formulation, is divided into:
1. alleviate completely (CR), visible tumor disappears, and continues more than one month;
2. partial rcsponse (PR), two maximum orthogonal diameter products of tumor dwindle more than 50%, and keep more than 1 month;
3. stable (SD), two maximum orthogonal diameter products of tumor dwindle less than 50%, increase and are no more than 25%, and continue more than one month;
4. ((PD), the orthogonal diameter product of two maximums of tumor increases over 25% in deterioration.
5, therapeutic outcome: alleviate 103 examples completely, partial rcsponse 14 examples, stablize 12 examples, worsens 9 examples.Effective percentage (CR+PR) is 84.8%, and coefficient of stabilization (CR+PR+SD) is 93.5%.In early stage 49 routine early hepatocarcinomas, there are 44 examples to cure (tumor all disappears, and follows up a case by regular visits to not recurrence in 1 year) simultaneously.
6, toxic and side effects analysis
In the 138 routine patients that observe, take after Chinese medicine of the present invention, 2 routine laxativeness, the probability that occurs side reaction is only 1.45%, through disposing to the ill side reaction, disappears, all the other are without any side effects.
In sum, the present invention is used for the treatment of the Chinese medicine decoction of gastric cancer, through clinical trial, shows that it can effectively suppress gastric cancer development, improves patient's symptom, sign, and without obvious toxic-side effects.
Two, model case
Case 1: poplar, female, 72 years old.Patient's symptom is that stomach is vexed swollen, and dyspepsia is sometimes felt sick, vomitted, and is difficult to swallow during feed.Within one month, get off, obviously become thin, in hospital, be diagnosed as on inspection gastric cancer late period, tumor size differs, and the diameter 3.3cmx2.8cm of maximum tumor, because patient is advanced in age, is not suitable for operative treatment, accepts treatment by Chinese herbs of the present invention afterwards.After the course for the treatment of, stomach discomfort symptom obviously alleviates, and have a meal and also more and more can eat, sleep, people is also spiritual.After the 5th of the patient medicine course for the treatment of is eaten up, sensation health is solid as before disease, and body weight has also increased.And serve on two the course for the treatment of medicine.Through hospital, check: indices is normal, tumor disappears comprehensively.The recurrence of following up a case by regular visits to that so far there are no.
Case 2: Zhang, man, 58 years old.Patient is old gastropathy throughout the year, and health is always weaker, and flatulence stomachache is recently serious, the anorexia of feeling sick.Think it has been gastrointestinal sick offender always, by eating the stomach medicine of a little anti-inflammatory analgetics, maintain.Pain increased the weight of afterwards, and health is obvious thin and weak.Through hospital, be diagnosed as gastric cancer late period, the maximum tumor 3.5CMX3.3CM of stomach.Hospital considers that patient body situation is poor, and operation risk is very large.Started afterwards to take this patent Drug therapy.After the course for the treatment of, the phenomenons such as various pain symptoms and nauseating anorexia are greatly improved; After three courses for the treatment of, the maximum tumor of stomach is contracted to 1.8CMX1.5CM by 3.5CMX3.3CM.This patient take six the course for the treatment of medicine on inspection later, stomach size tumor all disappears.Take altogether eight the course for the treatment of medicine, thoroughly cured.
The specific embodiment
Embodiment 1: a kind of Chinese medicine decoction for the treatment of gastric cancer, by the crude drug of following weight, made: 10 grams of Olibanums, 10 grams of Cortex Cinnamomis, 15 grams of Spica Prunellaes, 15 grams of Lignum Aquilariae Resinatum, 15 grams of Radix Ophiopogonis, 15 grams of Rhizoma Curcumae, 15 grams of Myrrhas, 15 grams of the Radixs Astragali, 15 grams of Radix Salviae Miltiorrhizaes, 15 grams of Fructus Ligustri Lucidi, 15 grams of Fructus Schisandrae Chinensis, 15 grams of Radix Angelicae Sinensis, 15 grams of Radix Paeoniae Rubra, 15 grams of Rhizoma Chuanxiongs, 10 grams of Rhizoma Corydalis, 10 grams of Radix Rehmanniae, 10 grams of Ganodermas, 10 grams of Herba Hedyotidis Diffusaes, 10 grams of Rhizoma Polygonati Odorati, 10 grams of Cortex Moutans, 10 grams of Pseudobulbus Cremastrae Seu Pleioness, 10 grams of Fructus Aurantii Immaturuss, 10 grams of Radix Arnebiae (Radix Lithospermi)s, 5 grams, Moschus.
Preparation and instructions of taking: first above-mentioned raw materials is soaked in water 2 hours, decocting in water 30 minutes, pours out medicinal liquid; Add again decocting in water 30 minutes, pour out medicinal liquid; Twice medicinal liquid amalgamation rises, and cools completely, and respectively at half an hour before breakfast, within after supper two hours, takes.Serveing on 20 days is a course for the treatment of.
Claims (1)
1. a Chinese medicine decoction for the treatment of gastric cancer, it is characterized in that, by the crude drug of following weight, made: 10 grams of Olibanums, 10 grams of Cortex Cinnamomis, 15 grams of Spica Prunellaes, 15 grams of Lignum Aquilariae Resinatum, 15 grams of Radix Ophiopogonis, 15 grams of Rhizoma Curcumae, 15 grams of Myrrhas, 15 grams of the Radixs Astragali, 15 grams of Radix Salviae Miltiorrhizaes, 15 grams of Fructus Ligustri Lucidi, 15 grams of Fructus Schisandrae Chinensis, 15 grams of Radix Angelicae Sinensis, 15 grams of Radix Paeoniae Rubra, 15 grams of Rhizoma Chuanxiongs, 10 grams of Rhizoma Corydalis, 10 grams of Radix Rehmanniae, 10 grams of Ganodermas, 10 grams of Herba Hedyotidis Diffusaes, 10 grams of Rhizoma Polygonati Odorati, 10 grams of Cortex Moutans, 10 grams of Pseudobulbus Cremastrae Seu Pleioness, 10 grams of Fructus Aurantii Immaturuss, 10 grams of Radix Arnebiae (Radix Lithospermi)s, 5 grams, Moschus.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104083643A (en) * | 2014-07-24 | 2014-10-08 | 黄武 | Traditional Chinese medicinal composition for treating tumors, early and mid-term cancers and preparation method of traditional Chinese medicinal composition |
| CN105726816A (en) * | 2016-03-31 | 2016-07-06 | 广州暨南生物医药研究开发基地有限公司 | Traditional Chinese medicine composition containing folium artemisiae argyi for treating stomach cancer and preparation method of traditional Chinese medicine composition |
| CN106138790A (en) * | 2015-04-01 | 2016-11-23 | 刘大仟 | A kind of Chinese medicine composition treating gastric cancer |
| CN106620263A (en) * | 2016-10-17 | 2017-05-10 | 南宁多灵生物科技有限公司 | Traditional Chinese medicine for treating gastric cancer |
-
2013
- 2013-12-19 CN CN201310705970.7A patent/CN103690889B/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| 那坤等: "中医药治疗胃癌前病变的研究进展", 《中国中医基础医学杂志》, vol. 19, no. 8, 31 August 2013 (2013-08-31), pages 980 - 982 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104083643A (en) * | 2014-07-24 | 2014-10-08 | 黄武 | Traditional Chinese medicinal composition for treating tumors, early and mid-term cancers and preparation method of traditional Chinese medicinal composition |
| CN106138790A (en) * | 2015-04-01 | 2016-11-23 | 刘大仟 | A kind of Chinese medicine composition treating gastric cancer |
| CN105726816A (en) * | 2016-03-31 | 2016-07-06 | 广州暨南生物医药研究开发基地有限公司 | Traditional Chinese medicine composition containing folium artemisiae argyi for treating stomach cancer and preparation method of traditional Chinese medicine composition |
| CN106620263A (en) * | 2016-10-17 | 2017-05-10 | 南宁多灵生物科技有限公司 | Traditional Chinese medicine for treating gastric cancer |
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