CN103667304B - 核酸 - Google Patents
核酸 Download PDFInfo
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- CN103667304B CN103667304B CN201310487984.6A CN201310487984A CN103667304B CN 103667304 B CN103667304 B CN 103667304B CN 201310487984 A CN201310487984 A CN 201310487984A CN 103667304 B CN103667304 B CN 103667304B
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2318/00—Antibody mimetics or scaffolds
- C07K2318/10—Immunoglobulin or domain(s) thereof as scaffolds for inserted non-Ig peptide sequences, e.g. for vaccination purposes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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| GB201214007D0 (en) | 2012-08-07 | 2012-09-19 | Scancell Ltd | Anti-tumour immune responses to modified self-epitopes |
| EP3253419A1 (en) | 2015-02-02 | 2017-12-13 | The University of Birmingham | Targeting moiety peptide epitope complexes having a plurality of t-cell epitopes |
| WO2017210149A1 (en) * | 2016-05-31 | 2017-12-07 | Igc Bio, Inc. | Compositions and methods for generating an antibody library |
| US11419928B2 (en) | 2017-10-25 | 2022-08-23 | The Johns Hopkins University | Methods and compositions for treating cancer |
| GB201815041D0 (en) | 2018-09-14 | 2018-10-31 | Scancell Ltd | Epitopes |
| WO2021195089A1 (en) | 2020-03-23 | 2021-09-30 | Sorrento Therapeutics, Inc. | Fc-coronavirus antigen fusion proteins, and nucleic acids, vectors, compositions and methods of use thereof |
| CN111423504B (zh) * | 2020-04-17 | 2021-03-26 | 安徽高安生物医学科技有限公司 | 黑色素瘤特异性抗原肽、肽复合物以及人工抗原呈递细胞 |
| BR112023002195A2 (pt) | 2020-08-26 | 2023-03-14 | Scancell Ltd | Ácido nucleico que codifica um polipeptídeo, vetor, peptídeo, e composição de vacina |
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| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
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| EP1181320B1 (en) * | 1999-04-27 | 2011-03-09 | Nevagen LLC | Somatic transgene immunization and related methods |
| US7067110B1 (en) * | 1999-07-21 | 2006-06-27 | Emd Lexigen Research Center Corp. | Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
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| EP2134357A2 (en) | 2009-12-23 |
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| WO2008116937A2 (en) | 2008-10-02 |
| PL2134357T3 (pl) | 2018-03-30 |
| CN101678092B (zh) | 2014-04-02 |
| CN103667304A (zh) | 2014-03-26 |
| KR20150013357A (ko) | 2015-02-04 |
| EP2193803B1 (en) | 2011-10-19 |
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| WO2008116937A3 (en) | 2009-01-22 |
| ATE529128T1 (de) | 2011-11-15 |
| PT2193803E (pt) | 2012-01-16 |
| BRPI0808599A2 (pt) | 2019-01-08 |
| EP2134357B1 (en) | 2017-05-31 |
| JP5415399B2 (ja) | 2014-02-12 |
| ZA200907242B (en) | 2010-11-24 |
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| CN101678092A (zh) | 2010-03-24 |
| AU2008231723B2 (en) | 2013-05-16 |
| KR20160091458A (ko) | 2016-08-02 |
| AU2008231723A1 (en) | 2008-10-02 |
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