CN103638412B

CN103638412B - Multiple-effect Chinese medicinal formulae of a kind of quick elimination pulmonary persistent ailment and preparation method thereof

Info

Publication number: CN103638412B
Application number: CN201310685598.8A
Authority: CN
Inventors: 王文兮
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-12-16
Filing date: 2013-12-16
Publication date: 2016-04-27
Anticipated expiration: 2033-12-16
Also published as: CN103638412A

Abstract

The present invention relates to multiple-effect Chinese medicinal formulae of a kind of quick elimination respiratory tract persistent ailment and preparation method thereof, this prescription with Cordyceps, Bulbus Fritillariae Cirrhosae, Gecko, Fructus Schisandrae Chinensis, Cornu Bubali silk and Margarita altogether for monarch drug, be the first general plan with reinforcement and elimination in combination, be aided with the power of the giving consideration to both the incidental and fundamental of two groups of ministerial drugs, it is basic that respiratory tract persistent ailments are eliminated on points three tunnels, fast and multiple-effect.Prescription treatment bronchial asthma total effective rate of the present invention is 83%; Emphysema total effective rate is 86%; Bronchitis is 89%; Serious symptom cough is 91%.

Description

Multiple-effect Chinese medicinal formulae of a kind of quick elimination pulmonary persistent ailment and preparation method thereof

Technical field

The invention belongs to technical field of Chinese medicine, in particular to a kind of multiple-effect Chinese medicinal formulae and preparation method thereof of quick elimination respiratory tract persistent ailment.

Background technology

Pulmonary's persistent ailment, the most lasting with asthma, recurrent exerbation, is continuous and does not heal.Change according to the season and the change of circumstances also make disease show effect or increase the weight of.Belong to respiratory anaphylactic disease, the traditional Chinese medical science belongs to heavy breathing, breathes heavily ' phlegm retention ' category.Its pathology principal element is ' expectorant ', and by affection of exogenous wind-cold, latent phlegm is at lung, and overwork, feelings will loses inducements and falling ill such as supporting.It has been generally acknowledged that morbidity has its source in lung and kidney, lung governing qi, kidney improving inspiration by invigorating kidney-QI, gas comes from as at all for lung.Be divided into again spleen-deficient, deficiency of the lung type, renal deficiency type and partially cold type and partial heat type.Once simulataneous insufficiency and excessive, multi viscera is deficient, is rather thorny disease.Now mostly be symptomatic treatment in acute condition, when sick, multiplex hormone controls, and relieving the primary symptom in a chronic case is had no way of doing it, if chance typing is improper, and the situations such as treatment delay, prognosis mala.Patient is agonizing especially.

Summary of the invention

The object of the present invention is to provide multiple-effect Chinese medicinal formulae of a kind of quick elimination respiratory tract persistent ailment and preparation method thereof.This Chinese medicinal formulae is secret prescription handed down in the family from generation to generation, and asthmatic patient can make wheezing sound eliminate fast after taking, and makes asthma be effectively suppressed simultaneously.In addition, look for another way due to dialectical, therefore other pulmonary's persistent ailments such as emphysema, serious symptom cough and acute/chronic bronchitis also have immediate effect.

The object of the present invention is achieved like this:

A kind of multiple-effect Chinese medicinal formulae of quick elimination respiratory tract persistent ailment, the consumption of each traditional Chinese medicinal material raw materials component of this prescription is: Cordyceps 1-2g, Gecko a pair, Bulbus Fritillariae Cirrhosae 10-15g, Fructus Schisandrae Chinensis 10-15g, Cornu Bubali silk 30-45g, Margarita 0.5-1g, fruit-rind of Chinese trichosanthes 15-25g, Semen Armeniacae Amarum 10-15g, Radix Asteris 15-20g, Radix Stemonae 15-20g, Exocarpium Citri Rubrum 10-15g, Vascular aurantii 10-15g, Folium Eriobotryae 15-20g, Radix Adenophorae (Radix Glehniae) 10-15g, Bulbus Lilii 15-20g, Flos Lonicerae 15-20g, Radix Scutellariae 10-15g, Fructus Forsythiae 15-25g, Radix Bupleuri 10-15g, Rhizoma Pinelliae Preparatum 5-10g, Placenta Hominis 10-15g, Gypsum Fibrosum 15-30g, Radix Platycodonis 5-10g.

In a most preferred embodiment of the present invention, the consumption eliminating each traditional Chinese medicinal material raw materials component in the multiple-effect Chinese medicinal formulae of respiratory tract persistent ailment as mentioned above is fast: Cordyceps 2g, Gecko a pair, Bulbus Fritillariae Cirrhosae 15g, Fructus Schisandrae Chinensis 15g, Cornu Bubali silk 45g, Margarita 1g, fruit-rind of Chinese trichosanthes 25g, Semen Armeniacae Amarum 15g, Radix Asteris 20g, Radix Stemonae 20g, Exocarpium Citri Rubrum 15g, Vascular aurantii 15g, Folium Eriobotryae 20g, Radix Adenophorae (Radix Glehniae) 15g, Bulbus Lilii 20g, Flos Lonicerae 20g, Radix Scutellariae 15g, Fructus Forsythiae 25g, Radix Bupleuri 15g, Rhizoma Pinelliae Preparatum 10g, Placenta Hominis 15g, Gypsum Fibrosum 30g, Radix Platycodonis 10g.

The Gecko that the present invention relates to is the entirety of Gekkonidae animal Gecko removing internal organs.Cornu Bubali silk is the angle of Babalus bubalis L., makes Cornu Bubali silk after riving.The fruit-rind of Chinese trichosanthes is the peel of cucurbitaceous plant Fructus Trichosanthis or trichosanthes rosthornii Harms etc.Radix Asteris and Radix Asteris are a kind of common feverfews, nourishing the lung to keep the adverse QI downward; Preventing phlegm from forming and stopping coughing.Exocarpium Citri Rubrum is the dry outside rind of rutaceae orange CitrusreticulataBlanco and variety thereof.Vascular aurantii has another name called Fructus Citri tangerinae silk, Fructus Citri tangerinae muscle, is the grain in the peel of rutaceae orange CitrusreticulataBlanco.Radix Adenophorae (Radix Glehniae) formal name used at school (Adenophorastricta), Campanulaceae, is used as medicine with root, clearing away heat and nourishing YIN, and nourishing the lung to arrest cough cures mainly tracheitis, pertussis, cough due to lung-heat, coughs up phlegm yellow thick.Bulbus Lilii selects the dry meat scale leaf of liliaceous plant tiger lily LiliumlancifoliumThunb..Folium Eriobotryae selects the dried leaves of dicotyledon Rosaceae Rosaceae Folium Eriobotryae Eriobotryajaponica (Thunb.) Lindl..The dry root of labiate Radix Scutellariae ScutellariabaicalensisGeorgi selected by Radix Scutellariae.Flos Lonicerae is selected from the dry flower of caprifoliaceae plant Radix Ophiopogonis (LonicerajaponicaThunb).Fructus Forsythiae is selected from Oleaceae (Oleaceae) Forsythia (Forsythia) plant Fructus Forsythiae (Forsythiasuspensa(Thunb.) Vahl) dry fruit.The dry root of umbelliferae bupleurum or Radix Bupeuri Scorzonerfolii. selected by Radix Bupleuri.Rhizoma Pinelliae Preparatum is the tuber of the aroid Rhizoma Pinelliae (Pinelliaternata (Thunb) Breit.).The dry Placenta Hominis that Placenta Hominis selects healthy puerpera to give birth to.The root of dicotyledon campanulaceae Campanulaceae Radix Platycodonis Platycodongrandiflorum (Jacq.) A.DC. selected by Radix Platycodonis.

The multiple-effect Chinese medicinal formulae of quick elimination respiratory tract persistent ailment of the present invention, is applicable to treatment asthma, emphysema, serious symptom cough and acute/chronic bronchitis.Especially be more suitable for treating asthma.

The preparation method of the multiple-effect Chinese medicinal formulae of quick elimination respiratory tract persistent ailment of the present invention, the method is that after described traditional Chinese medicinal material raw materials grouping being decocted, all decocting liquids are obtained by mixing Chinese medicinal formulae, and described grouping decocts and comprises: Cordyceps list is decocted by (1); (2) by Margarita levigation end with Cornu Bubali silk, Bulbus Fritillariae Cirrhosae together with slow fire boiling; (3) Fructus Schisandrae Chinensis is decocted with the Gecko removing eyes; (4) after Placenta Hominis and Gypsum Fibrosum being soaked 1 hour, upper big fire is boiled, then is decocted first 10 minutes with slow fire; (5) by the fruit-rind of Chinese trichosanthes, Semen Armeniacae Amarum, Radix Asteris, the Radix Stemonae, Radix Adenophorae (Radix Glehniae), Exocarpium Citri Rubrum, Vascular aurantii, Folium Eriobotryae, Bulbus Lilii, Radix Scutellariae, Fructus Forsythiae, Radix Bupleuri and Rhizoma Pinelliae Preparatum mixing, after adding water boil, big fire decocts; (6) by Flos Lonicerae and Radix Platycodonis mixing, big fire decocts.This preparation method has as much as possible retains original property of medicine and by strengthening with boiling and play the feature of the property of medicine.

The present invention is with Cordyceps, Bulbus Fritillariae Cirrhosae, Gecko, Fructus Schisandrae Chinensis, Cornu Bubali silk and Margarita altogether for monarch drug, and Cordyceps is warm in nature, returns spleen kidney, can protect lung qi, the kidney invigorating and essence nourishing.Cordyceps and Cordyceps decoct have dilating effect to bronchial smooth muscle, can increase the phenol red excretion of trachea, have phlegm-dispelling functions; Bulbus Fritillariae Cirrhosae cold nature, returns lung.There are clearing heat and moistening lung, preventing phlegm from forming and stopping coughing, the functions such as resolving depression eliminating stagnation.Bulbus Fritillariae Cirrhosae and contained alkaloid thereof have obvious eliminating phlegm and relieving cough effect.Total alkaloids draws to acetylcholine and histamine the Cavia porcellus breathed heavily significant antiasthmatic effect; The immunologic function of Gecko energy enhancing body, can anoxia enduring.There is spasmolytic the effect such as to relieving asthma.Three is that monarch drug is first, solves spasmolytic effect of lung, renal function and bronchial smooth muscle.Have deficiency of vital energy person again, add Fructus Schisandrae Chinensis QI invigorating improving inspiration by invigorating kidney-QI, power is distinguished.Be that multiple miscellaneous diseases also can dual-purpose wonderful.Cornu Bubali silk 5 is all its latent heat of town with Margarita, separates its pyretic toxicity.Gather the reason of monarch drug altogether.

Ministerial drug first group is: the fruit-rind of Chinese trichosanthes, Semen Armeniacae Amarum, Radix Asteris, the Radix Stemonae, Radix Adenophorae (Radix Glehniae), Exocarpium Citri Rubrum, Vascular aurantii, Folium Eriobotryae and Bulbus Lilii, for pulmonary's antiinflammatory, relieving cough and asthma, reduce phlegm, eliminating stagnation, lung moistening key medicine.Semen Armeniacae Amarum 5 with the Radix Stemonae, the fruit-rind of Chinese trichosanthes, Radix Asteris can relieving cough and asthma, the fruit-rind of Chinese trichosanthes, can removing heat from the lung and dissipating phlegm, promoting the circulation of QI relieving stuffiness of the chest by dispersing aggregation of pathogens.The Radix Stemonae, its ethanol immersion has antibacterial action to Staphylococcus aureus and Staphylococcus albus, beta hemolytic streptococcus.Be sedation to respiratory center, thus reach antitussive and antiasthmatic effect.Radix Asteris, no matter diseases caused by exogenous pathogenic factor, internal injury all can be used.The strongly fragrant lung of wind and cold, cough is more than, and expectoration is not well all can be used.Exocarpium Citri Rubrum compatibility Vascular aurantii has drying dampness to eliminate phlegm, the merit of regulating qi and dredging collateral.

Flos Lonicerae, Radix Scutellariae, Fructus Forsythiae, Radix Bupleuri, Rhizoma Pinelliae Preparatum are second group of ministerial drug, except Flos Lonicerae, Radix Scutellariae, Fructus Forsythiae anti-inflammation, outside heat-clearing and toxic substances removing, and Radix Bupleuri compatibility Rhizoma Pinelliae Preparatum liver and gall of supervising the cooking are strongly fragrant through it, reconciling superficies and interior, elevate a turnable ladder yang-energy.Dialectical further, multiple upper respiratory tract persistent ailment is not only the disease of spleen kidney, lung kidney, more has the suspicion of few sun.

Ministerial drug of the present invention why two groups of appearance, are rule for the treatment of of surpassing our predecessors, not only in resolving phlegm and relieving asthma, antitussive eliminating stagnation is made an effort, also will set about on heat-clearing and toxic substances removing, anti-inflammation, the half exterior and half interior of the merit of few sun, makes respiratory tract sensible, smooth and easy naturally reasonable up and down in addition.Also persistent ailment and not Liu Tadao is thoroughly being removed, therefore quick-acting and multiple-effect.

Radix Adenophorae (Radix Glehniae) group medicine Folium Eriobotryae, Bulbus Lilii, get the use of yin nourishing lung benefiting, the allergic asthma that Bulbus Lilii causes antihistamine and sedation; Its aqueous extract is strong, resisting oxygen lack in addition, has obvious effect to the weak transient anoxia that bronchial asthma causes.The method that tripartite keeps fit for respiratory tract persistent ailment, adjuvant drug is first-selected; Take second place, separately help Placenta Hominis, Gypsum Fibrosum, the oiliness not dry benefiting qi and nourishing blood of Placenta Hominis, in love product, not only having immunization also can enhancing body resistance, and anti-allergic effects.And Gypsum Fibrosum can clearing away heat-fire, the two one is mended one and lets out the also wonderful of assistant.Mainly with consumption with the passing of time, recurrent exerbation, prolong silk floss more not famous, the tonification of Placenta Hominis, without scorching anxiety, condition separately has joining of Gypsum Fibrosum to chronic respiratory persistent ailment, brings out the best in each other undoubtedly.Only Radix Platycodonis draws all medicines to the part of the body cavity above the diaphragm housing the heart and lungs, Shi Zheye.

So far, elimination upper respiratory tract persistent ailment prescription set forth in the present invention, with quick, multiple-effect for invention feature, the maximum course of disease of asthma disease is more than 40 year, and the age is 92 years old, and minimum patient is trimestral baby, and from falling ill to using, this prescription healing time is for more than the moon.Among most of patients have and use hormone history.Infant group eczema infant person is many, for the course of disease is long, refractory more, recurrent is common, because of the many relatively weakness of the spleen and stomach of its ferritic, also due to eating and drinking without temperance, lose the day after tomorrow caused by supporting, therefore the product separately adding removing food stagnancy antitussive in infant group are dealt with problems arising from an accident, and can reach healing object.Except this, middle aged group of feature is debating of negative and positive.Extremely cloudy and positive, the road of negative and positive accommodation nothing more than.Three groups of asthmatic patients total effective rate after taking this prescription is 83%; Emphysema total effective rate is 86%; Bronchitis is 89%; Serious symptom cough is 91%.As can be seen here, lung kidney, the spleen kidney opinion person of controlling in the past, then be aided with the opinion of few sun.Side is comprehensive.Grab its key, at one stroke.

Detailed description of the invention

Be below specific embodiments of the invention, technical scheme of the present invention is done to describing further, but protection scope of the present invention be not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.

Embodiment one, Kong Yuda, in October, 2007 is raw, in February, 2008 morbidity, from the beginning of just cough, then starts to occur wheezing sound within three days, and remaining bimester of suffering from eczema before this boy baby, by Harbin, children's hospital is diagnosed as allergic asthma.Prescription consumption is: Cordyceps 1g, Gecko a pair, Bulbus Fritillariae Cirrhosae 10g, Fructus Schisandrae Chinensis 10g, Cornu Bubali silk 30g, Margarita 0.5g, fruit-rind of Chinese trichosanthes 15g, Semen Armeniacae Amarum 10g, Radix Asteris 15g, Radix Stemonae 15g, Exocarpium Citri Rubrum 10g, Vascular aurantii 10g, Folium Eriobotryae 15g, Radix Adenophorae (Radix Glehniae) 10g, Bulbus Lilii 15g, Flos Lonicerae 15g, Radix Scutellariae 10g, Fructus Forsythiae 15g, Radix Bupleuri 10g, Rhizoma Pinelliae Preparatum 5g, Placenta Hominis 10g, Gypsum Fibrosum 15g, Radix Platycodonis 5g.Decocting extracting juice 100mL, sub-service sooner or later, potion on the one.By taking the recovery from illness in 45 days of this prescription.

Embodiment two, Zhang, 65 years old, premorbid had the smoking history in more than 30 years, can not independent ambulation, dyspnea during morbidity.AC125 index reaches more than 1000, admitted to hospital by Wuhan Concord Hospital Pneumology Department, and notified preparation funeral affairs, taking the party's agent dose is: Cordyceps 2g, Gecko a pair, Bulbus Fritillariae Cirrhosae 15g, Fructus Schisandrae Chinensis 15g, Cornu Bubali silk 45g, Margarita 1g, fruit-rind of Chinese trichosanthes 25g, Semen Armeniacae Amarum 15g, Radix Asteris 20g, Radix Stemonae 20g, Exocarpium Citri Rubrum 15g, Vascular aurantii 15g, Folium Eriobotryae 20g, Radix Adenophorae (Radix Glehniae) 15g, Bulbus Lilii 20g, Flos Lonicerae 20g, Radix Scutellariae 15g, Fructus Forsythiae 25g, Radix Bupleuri 15g, Rhizoma Pinelliae Preparatum 10g, Placenta Hominis 15g, Gypsum Fibrosum 30g, Radix Platycodonis 10g.Decocting extracting juice 600-800mL, sub-service sooner or later, potion on the one.Remaining and heal the bimester of taking this prescription.

Embodiment three, Zhang Shuzhen, female, 93 years old, in Harbin, First Hospital is diagnosed as bronchitis, and find that there is mycoplasma infection, suffer from diabetes simultaneously, the state of an illness was not effectively controlled in 20 days in hospital, taking the party's agent dose is: Cordyceps 2g, Gecko a pair, Bulbus Fritillariae Cirrhosae 12g, Fructus Schisandrae Chinensis 12g, Cornu Bubali silk 40g, Margarita 1g, fruit-rind of Chinese trichosanthes 18g, Semen Armeniacae Amarum 12g, Radix Asteris 15g, Radix Stemonae 20g, Exocarpium Citri Rubrum 12g, Vascular aurantii 12g, Folium Eriobotryae 15g, Radix Adenophorae (Radix Glehniae) 15g, Bulbus Lilii 15g, Flos Lonicerae 20g, Radix Scutellariae 15g, Fructus Forsythiae 20g, Radix Bupleuri 15g, Rhizoma Pinelliae Preparatum 8g, Placenta Hominis 12g, Gypsum Fibrosum 20g, Radix Platycodonis 8g.Decocting extracting juice about 500mL, sub-service sooner or later, potion on the one.By taking the recovery from illness in month of this prescription.

Claims

1. eliminate the multiple-effect Chinese drugs agentia of respiratory tract persistent ailment fast for one kind, it is characterized in that: the consumption of each traditional Chinese medicinal material raw materials component of this medicament is: Cordyceps 1-2g, Gecko a pair, Bulbus Fritillariae Cirrhosae 10-15g, Fructus Schisandrae Chinensis 10-15g, Cornu Bubali silk 30-45g, Margarita 0.5-1g, fruit-rind of Chinese trichosanthes 15-25g, Semen Armeniacae Amarum 10-15g, Radix Asteris 15-20g, Radix Stemonae 15-20g, Exocarpium Citri Rubrum 10-15g, Vascular aurantii 10-15g, Folium Eriobotryae 15-20g, Radix Adenophorae (Radix Glehniae) 10-15g, Bulbus Lilii 15-20g, Flos Lonicerae 15-20g, Radix Scutellariae 10-15g, Fructus Forsythiae 15-25g, Radix Bupleuri 10-15g, Rhizoma Pinelliae Preparatum 5-10g, Placenta Hominis 10-15g, Gypsum Fibrosum 15-30g, Radix Platycodonis 5-10g.

2. eliminate the multiple-effect Chinese drugs agentia of respiratory tract persistent ailment according to claim 1 fast, it is characterized in that: the consumption of each traditional Chinese medicinal material raw materials component of this medicament is: Cordyceps 2g, Gecko a pair, Bulbus Fritillariae Cirrhosae 15g, Fructus Schisandrae Chinensis 15g, Cornu Bubali silk 45g, Margarita 1g, fruit-rind of Chinese trichosanthes 25g, Semen Armeniacae Amarum 15g, Radix Asteris 20g, Radix Stemonae 20g, Exocarpium Citri Rubrum 15g, Vascular aurantii 15g, Folium Eriobotryae 20g, Radix Adenophorae (Radix Glehniae) 15g, Bulbus Lilii 20g, Flos Lonicerae 20g, Radix Scutellariae 15g, Fructus Forsythiae 25g, Radix Bupleuri 15g, Rhizoma Pinelliae Preparatum 10g, Placenta Hominis 15g, Gypsum Fibrosum 30g, Radix Platycodonis 10g.

3. according to claim 1 or 2, eliminate the multiple-effect Chinese drugs agentia of respiratory tract persistent ailment fast, it is characterized in that: described respiratory tract persistent ailment comprises asthma, emphysema, serious symptom cough and acute/chronic bronchitis.

4. eliminate the multiple-effect Chinese drugs agentia of respiratory tract persistent ailment according to claim 3 fast, it is characterized in that: described respiratory tract persistent ailment is asthma.

5. the preparation method of the multiple-effect Chinese drugs agentia of quick elimination respiratory tract persistent ailment according to claim 1, it is characterized in that the method is after described traditional Chinese medicinal material raw materials grouping being decocted, all decocting liquids are obtained by mixing Chinese drugs agentia, and described grouping decocts and comprises: Cordyceps list is decocted by (1); (2) by Margarita levigation end with Cornu Bubali silk, Bulbus Fritillariae Cirrhosae together with slow fire boiling; (3) Fructus Schisandrae Chinensis is decocted with the Gecko removing eyes; (4) after Placenta Hominis and Gypsum Fibrosum being soaked 1 hour, upper big fire is boiled, then is decocted first 10 minutes with slow fire; (5) by the fruit-rind of Chinese trichosanthes, Semen Armeniacae Amarum, Radix Asteris, the Radix Stemonae, Radix Adenophorae (Radix Glehniae), Exocarpium Citri Rubrum, Vascular aurantii, Folium Eriobotryae, Bulbus Lilii, Radix Scutellariae, Fructus Forsythiae, Radix Bupleuri and Rhizoma Pinelliae Preparatum mixing, after adding water boil, big fire decocts; (6) by Flos Lonicerae and Radix Platycodonis mixing, big fire decocts.