CN103638274B

CN103638274B - Medicine for treating infantile balanitis and preparation method of medicine

Info

Publication number: CN103638274B
Application number: CN201310673030.4A
Authority: CN
Inventors: 苏振华
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-12-12
Filing date: 2013-12-12
Publication date: 2015-06-03
Anticipated expiration: 2033-12-12
Also published as: CN103638274A

Abstract

The invention discloses a medicine for treating infantile balanitis and a preparation method of the medicine. The medicine is mainly prepared from salvia prionitis, fructus kochiae, arnebia euchroma, herba schizonepetae, garlic, agrimonia pilosa ledeb, purslane, spina gleditsiae, sophora flavescens, achyranthes bidentata and other medicines in a certain weight ratio. The medicine has the functions of clearing heat and removing toxicity, dissipating blood stasis and reducing edema, drawing out poison and clearing pus, is quick in response and good in curative effect when used for treating infantile balanitis, and does not have toxic or side effect.

Description

A kind ofly treat medicine of children's's balanitis and preparation method thereof

Technical field

The present invention relates to and a kind ofly treat medicine of children's's balanitis and preparation method thereof, belong to the field of Chinese medicines.

Technical background

Children's's balanitis refers to the inflammation of the mucosa that children's's glans part is caused by factors such as wound, stimulation or infection.Can be caused by many factors, as the various physical factor stimulations, redundant prepuce, phimosis, smegma stimulation, various infection etc. of local.Because Western medicine cannot effectively treat children's's balanitis, therefore there is great demand in the Chinese medicine of people to rapid, effective treatment children's balanitis, up to now, also do not find about relevant report of the present invention.

Summary of the invention

The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment children's balanitis, thus completes the present invention.

Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment children's balanitis.

Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.

Medicine of the present invention selects Arisaema balansae Engl., the Fructus Kochiae, Radix Arnebiae (Radix Lithospermi), Herba Schizonepetae, Bulbus Allii, Herba Agrimoniae, Herba Portulacae, Spina Gleditsiae, Radix Sophorae Flavescentis, Radix Achyranthis Bidentatae, Bombyx Batryticatus, Flos Genkwa, Rhizoma Paridis, Margarita powder, Mel medicine to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat the recurrence of children's's balanitis.Arisaema balansae Engl. is selected to be that have heat clearing and inflammation relieving, the function of drawing out the pus, controls furuncle, innominate toxic swelling, parotitis, acute mastitis because the pungent fiber crops of its nature and flavor.Select the Fructus Kochiae to be because its nature and flavor sweetness and bitterness, cold, enter kidney, urinary bladder channel, have diuresis, the function of clearing away damp-heat, controls dysuria, gonorrhea, leukorrhagia, hernia, rubella, sore, scabies, pudendum pruritus due to damp pathogen.Radix Arnebiae (Radix Lithospermi) is selected to be because its nature and flavor earnestly, are trembled with fear, entered percardium, Liver Channel, have removing heat from blood, invigorate blood circulation, the function of heat-clearing and toxic substances removing, control warm macule, jaundice due to damp-heat, purpura, tell, be defeated in battle, hematuria, stranguria with turbid discharge, dysentery, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer.Select Herba Schizonepetae to be that temperature, enters lung, Liver Channel, deliver, dispel the wind, the function for the treatment of blood disorders because its nature and flavor are pungent, parch to black stops blooding, and cure cold heating, headache, laryngopharynx swelling and pain, apoplexy locked mouth, and spit blood, epistaxis, has blood in stool, metrorrhagia, puerperal blood faints, carbuncle, skin ulcer scabies, scrofula.Select Bulbus Allii to be that temperature, enters spleen, stomach, lung meridian because its nature and flavor are pungent, have the stagnant gas of row, warming the spleen and stomach ， Xiao mass in the abdomen, removing toxic substances, the function of parasite killing, controls eating accumulation, coldness and pain in the epigastrium, and edema distension, has loose bowels, dysentery, malaria, pertussis, carbuncle carbuncle poison, white bald tinea skin ulcer, snake bite and insect sting.Select Herba Agrimoniae to be because its nature and flavor toil, flat, enter lung, liver, spleen channel, have hemostasis, the function of stomach invigorating, controls spitting of blood, and spit blood, hematuria, has blood in stool, dysentery, bleeding not during menses, and impairment caused by overstrain takes off power, carbuncle, traumatic injury, wound hemorrhage.Select Herba Portulacae to be because its nature and flavor acid, cold, enter large intestine, liver, spleen channel, have heat-clearing and toxic substances removing, the function of loose blood detumescence, controls hematodiarrhoea pus and blood, pyretic stranguria, stranguria with blood, leukorrhagia, carbuncle malignant boil, erysipelas, scrofula.Select Spina Gleditsiae to be that temperature, searches wind, draw out pus by applying a plaster to the affected part because its nature and flavor are pungent, detumescence, the function of evacuation of pus, controls carbuncle, sore, leprosy, tinea skin ulcer, placenta retention.Radix Sophorae Flavescentis is selected to be that cold, enter liver, kidney, large intestine, small intestine meridian, have heat clearing away, dampness, the function of parasite killing, controls toxic-heat and blood stasis because its nature and flavor are bitter, discharging fresh blood stool, jaundice, leucorrhea with red and white discharge, infantile pneumonia, infantile malnutrition, acute tonsillitis, anal fistula, proctoptosis, skin pruritus, erosion of vulva pruritus due to damp pathogen, scrofula, scalds.Select Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid, flat, enter liver, kidney channel, life uses dissipating blood stasis blood, subduing inflammation, controls gonorrhea, hematuria, amenorrhea ， mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis is suffered from abdominal pain, sore throat, carbuncle, traumatic injury, ripe invigorating the liver and kidney, bone and muscle strengthening, controls waist kneecap pain, four fertile contractures, flaccidity syndrome and arthralgia syndrome.Bombyx Batryticatus is selected to be because its nature and flavor are pungent salty, flat, enter liver, lung, stomach warp, have expelling wind to relieve convulsion, the function of dissipating phlegm and resolving masses, control apoplectic aphasia ， Jing Epilepsy, wind syndrome of head, acute throat trouble, sore throat, scrofula tuberculosis, wind skin ulcer urticaria, erysipelas, mastitis.Flos Genkwa is selected to be that temperature, poisonous, relieve oedema or abdominal distension through diuresis or purgation, the function of clearing away phlegm, controls cough with asthma, edema, hypochondriac pain, carbuncle because its nature and flavor are worked hard.Select Rhizoma Paridis to be because its nature and flavor toil, cold, poisonous, enter the heart, Liver Channel, have heat-clearing and toxic substances removing, antiasthmatic-antitussive, the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., controls carbuncle, furuncle, scrofula, sore throat, chronic tracheitis, and infantile convulsion is twitched, snake bite and insect sting.Select Concha Margaritifera to be because its nature and flavor are salty, cool, enter the heart, liver two warp, have suppressing the hyperactive liver, YANG hyperactivity suppressing, arresting convulsion, the function of hemostasis, controls dizziness, tinnitus, cardiopalmus, insomnia, and demented ， Jing Epilepsy is spitted blood, epistaxis, metrorrhagia.Select Mel to be that flat, enter lung, spleen, large intestine channel, have invigorating middle warmer, moisturize, pain relieving, the function of removing toxic substances, controls xeropulmonary cough, dryness of the intestine constipation, gastralgia, nasal sinusitis, aphtha, the burning hot wound of soup because its nature and flavor are sweet, separate Aconitum Carmichaeli.

Detailed description of the invention

The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight

Arisaema balansae Engl. 2-6 gram of Fructus Kochiae 5-10 gram of Radix Arnebiae (Radix Lithospermi) 8-15 gram

Herba Schizonepetae 8-15 gram of Bulbus Allii 6-12 gram of Herba Agrimoniae 6-15 gram

Herba Portulacae 8-16 gram of Spina Gleditsiae 2-8 gram of Radix Sophorae Flavescentis 2-6 gram

Radix Achyranthis Bidentatae 5-10 gram of Bombyx Batryticatus 1-4 gram of Flos Genkwa 4-10 gram

Rhizoma Paridis 5-10 gram of Margarita powder 5-12 gram of Mel 40-100 gram

Be preferably

Arisaema balansae Engl. 4 grams of Fructus Kochiae 6 grams of Radix Arnebiae (Radix Lithospermi)s 10 grams

Herba Schizonepetae 10 grams of Bulbus Alliis 8 grams of Herba Agrimoniaes 8 grams

Herba Portulacae 10 grams of Spina Gleditsiaes 4 grams of Radix Sophorae Flavescentiss 4 grams

Radix Achyranthis Bidentatae 6 grams of Bombyx Batryticatus 2 grams of Flos Genkwas 5 grams

Rhizoma Paridis 6 grams of Margarita powder 8 grams of Mel 50 grams

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Arisaema balansae Engl.: the whole year can adopt, using fresh herb or dry;

2, the Fructus Kochiae: get crude drug, removing impurity, sieve removes chip;

3, Radix Arnebiae (Radix Lithospermi): clean, run through, section, dries;

4, Herba Schizonepetae: pick clean impurity, with water slightly bubble, pulls cutting out, dries;

5, Bulbus Allii: get fresh garlic, dials and removes crust;

6, Herba Agrimoniae: removing impurity undesirable root, cleans, runs through, cut off, dry;

7, Herba Portulacae: pick clean impurity, removing undesirable root, slightly moisten with water, cutting is dried;

8, Spina Gleditsiae: pick decontamination, is soaked in water, and runs through rear section, dries;

9, Radix Sophorae Flavescentis: pick clean impurity, removes residual stem, cleans earth, is soaked in water, pulls out, run through, and section, dries;

10, Radix Achyranthis Bidentatae: pick decontamination, cleans, softens, go reed, cutting, dry;

11, Bombyx Batryticatus: pick silk hair, cleans dirt, dries;

12, Flos Genkwa: pick clean impurity, sieve removes earth;

13, Rhizoma Paridis: autumn excavates, removing fibrous root, cleaning, drying;

14, Concha Margaritifera: pick decontamination, knock fragment, sieve dedust bits;

15, Mel: get pure Mel, temper with slow fire, filters skimming.

Two, prepare

1, the Arisaema balansae Engl. of described quantity, the Fructus Kochiae, Radix Arnebiae (Radix Lithospermi), Herba Schizonepetae, Bulbus Allii, Herba Agrimoniae, Herba Portulacae, Spina Gleditsiae, Radix Sophorae Flavescentis, Radix Achyranthis Bidentatae, Bombyx Batryticatus, Flos Genkwa, Rhizoma Paridis, Concha Margaritifera are pulverized respectively, smash altogether as pureed.

2, the Mel adding described weight in the above-mentioned medicine mud smash is mixed well into rare paste and get final product.

Medicine of the present invention has the function of heat-clearing and toxic substances removing, loose blood detumescence, evacuation of pus of drawing out pus by applying a plaster to the affected part, and is used for the treatment of children's's balanitis instant effect, good effect, does not recur.

Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.

The animal toxicity test of [test example 1] medicine of the present invention

Get West Germany rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, first exposes skin by rabbit abdominal part hair removing, then by the Herbal medicines for external use that mixes up at rabbit abdominal part baring skin place, then twine with gauze and tie up, once, continuous external application 5 days, observes administration reaction every day in drug of topical application every day, result shows that rabbit is movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1, physical data

Accept out-patient's totally 50 examples for medical treatment.

2, diagnostic criteria

Children's's balanitis onset initial stage the lighter, only Glans penis and Inner prepuce flushing, and with scratchiness.Pain and tenderness can be there is in severe one; Can occur in later stage foreskin to show fester, have yellow or cheese sample secretions, often with stink; Local is red and swollen, can affect and urinates and have urodynia.

3, Therapeutic Method

Selecting above-mentioned medicament, be applied to affected part to patient, the drug of topical application twice every day, 15 days is a course for the treatment of, two courses for the treatment of of the continuous drug of topical application.

4, efficacy assessment standard

Effective: children's's balanitis symptom is fully recovered, recover normal;

Take a turn for the better: children's's balanitis symptom alleviates, and the state of an illness progressively takes a turn for the better;

Invalid: not reach improvement standard person.

5, therapeutic outcome (seeing the following form):

In above-mentioned treatment, by Drug therapy children's balanitis patient 100 example of the present invention, effective 93 examples of result, obvious effective rate is 93%, and take a turn for the better 3 examples, and improvement rate is 3%, and invalid 4 examples, total effective rate is 96%.

Claims

1. treat a medicine for children's's balanitis, it is characterized in that: it is made up of the crude drug in following weight range:

Rhizoma Paridis 5-10 gram of Margarita powder 5-12 gram of Mel 40-100 gram.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

Rhizoma Paridis 6 grams of Margarita powder 8 grams of Mel 50 grams.

3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:

(1) get the raw materials ready

(1) Arisaema balansae Engl.: the whole year can adopt, using fresh herb or dry;

(2) Fructus Kochiae: get crude drug, removing impurity, sieve removes chip;

(3) Radix Arnebiae (Radix Lithospermi): clean, run through, section, dries;

(4) Herba Schizonepetae: pick clean impurity, with water slightly bubble, pulls cutting out, dries;

(5) Bulbus Allii: get fresh garlic, dials and removes crust;

(6) Herba Agrimoniae: removing impurity undesirable root, cleans, runs through, cut off, dry;

(7) Herba Portulacae: pick clean impurity, removing undesirable root, slightly moisten with water, cutting is dried;

(8) Spina Gleditsiae: pick decontamination, is soaked in water, and runs through rear section, dries;

(9) Radix Sophorae Flavescentis: pick clean impurity, removes residual stem, cleans earth, is soaked in water, pulls out, run through, and section, dries;

(10) Radix Achyranthis Bidentatae: pick decontamination, cleans, softens, go reed, cutting, dry;

(11) Bombyx Batryticatus: pick silk hair, cleans dirt, dries;

(12) Flos Genkwa: pick clean impurity, sieve removes earth;

(13) Rhizoma Paridis: autumn excavates, removing fibrous root, cleaning, drying;

(14) Concha Margaritifera: pick decontamination, knock fragment, sieve dedust bits;

(15) Mel: get pure Mel, temper with slow fire, filters skimming;

(2) prepare

(1) Arisaema balansae Engl. of described quantity, the Fructus Kochiae, Radix Arnebiae (Radix Lithospermi), Herba Schizonepetae, Bulbus Allii, Herba Agrimoniae, Herba Portulacae, Spina Gleditsiae, Radix Sophorae Flavescentis, Radix Achyranthis Bidentatae, Bombyx Batryticatus, Flos Genkwa, Rhizoma Paridis, Concha Margaritifera are pulverized respectively, smash as pureed altogether;

(2) Mel adding described weight in the above-mentioned medicine mud smash is mixed well into rare paste and get final product.