CN103623112A - Traditional Chinese medicine composition for treating cutaneous pruritus and preparation method - Google Patents
Traditional Chinese medicine composition for treating cutaneous pruritus and preparation method Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicine composition and in particular relates to a traditional Chinese medicine composition for treating cutaneous pruritus and also relates to a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition for treating cutaneous pruritus comprises the following components in parts by weight: 5-12 parts of cordate houttuynia, 5-15 parts of sophora flavescens, 5-15 parts of magnolia officinalis, 5-15 parts of cortex phellodendri, 2-8 parts of motherwort, 3-10 parts of schisandra chinensis, 2-10 parts of radix sileris, 2-8 parts of radix paeoniae alba, 1-7 parts of scutellaria baicalensis, 2-8 parts of mint, 1-10 parts of ligusticum wallichii, 1-6 parts of tribulus terrestris, 1-6 parts of paniculate swallowwort, 1-8 parts of radix angelicae, 5-10 parts of broom cypress fruit and 2-8 parts of mulberry twig. The medicament for treating cutaneous pruritus prepared by using the prescription and the method is simple and convenient in preparation method, wide in source of crude drugs and low in cost. The traditional Chinese medicine composition follows the prescription medication principle of traditional Chinese medicine, and is taken as after being decocted with water. Through clinical test, the traditional Chinese medicine composition is remarkable in curative effects, reliable in function, mild in medicine properties and free of toxic or side effects, the effective rate reaches more than 95% and the cure rate reaches 75%.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of skin pruritus, also relate to the preparation method of this Chinese medicine composition.
Background technology
General pruritus often for many general diseases occurring together onset symptoms ，Ru uremia, biliary cirrhosis, hyperthyroidism or go down, diabetes, malignant tumor and neuropsychiatric pruritus etc.The exopathogenic factor of general pruritus and environmental factors (comprising the biological or chemical material incentive in humidity, season, working environment), external used medicine, with the sebaceous gland of the strong soap of alkalescence and patient skin and sweat gland secretion hypofunction, to cause xerosis cutis etc. relevant.
The cause of disease of local pruritus is sometimes identical with general pruritus, as diabetes.Pruritus ani is how relevant with enterobiasis, blood stasis, anal fistula etc.Vulval pruritus is how relevant with leucorrhea, trichomonal vaginitis, Vaginal Fungi disease, gonorrhea and cervical cancer.Scrotal pruritus is often relevant with local Pi Wengao, hyperhidrosis, friction, fungal infection.The generation of pruritus is caused as the release of histamine, Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2, kassinin kinin and protease etc. by chemical mediator.
Be more common in adult, pruritus Chang Congyi place starts, and expands to gradually whole body.Normal be paroxysmal, and especially to attach most importance to night, severe patient is the aggravation of persistence pruritus companion paroxysmal, drinks, coffee, tea, emotion changes, the stimulation of pungent diet, mechanicalness are scratched, warm bedding, even certain hint can be impelled the outbreak of pruritus and increase the weight of., even there is the change of eczema sample, lichenification, pyoderma and lymphangitis and lymphadenitis in Chang Jifa scratch, blood crusts, pigmentation.
Skin pruritus is clinical comparatively common a kind of chronic dermatosis without former skin lesion, especially higher at winter-spring season sickness rate, skin pruritus patient skin is without any pimple, the colour of skin is normal, and in the time of can falling ill, but pruritus unbearably, can show as locality or general, be paroxysmal, can last for hours at every turn, especially with night for very, patient suffers untold misery.At present, the Western medicine for the treatment of skin pruritus, general all employings contain the outer of artificial hormone applies medicinal lotion or ointment or oral medicine, although drug effect is effective, alleviates to a certain extent pruritus symptom rapidly, is easier to tolerance, and relapse rate is high, and often with certain side effect.Easily there is the phenomenons such as pigementation, telangiectasis and keratodermatitis thicken in the outer agents area of wiping particularly, and clinical efficacy is still difficult satisfactory.The Chinese medicine for oral administration of some treatment skin pruritus, although determined curative effect, relapse rate are low after taking, it is effective slow, concerning skin pruritus critical patient, is difficult to resolve " matter of great urgency ".
Summary of the invention
In order to solve above-mentioned technical problem, the invention provides a kind of instant effect and the Chinese medicine composition for the treatment of skin pruritus that human body is had no side effect;
The present invention also provides the preparation method of above-mentioned Chinese medicine composition.
Chinese medicine composition of the present invention comprises the component of following portions by weight:
A kind of compositions for the treatment of skin pruritus of the present invention, said composition comprises the component of following portions by weight:
Preferably, a kind of compositions for the treatment of skin pruritus of the present invention, said composition comprises the component of following portions by weight:
Preferred, a kind of compositions for the treatment of skin pruritus of the present invention, said composition comprises the component of following portions by weight:
Preferred, a kind of compositions for the treatment of skin pruritus of the present invention, said composition comprises the component of following portions by weight:
The preparation method of the compositions for the treatment of skin pruritus of the present invention, comprises following step:
Get Herba Houttuyniae, Radix Sophorae Flavescentis, Cortex Magnoliae Officinalis, Cortex Phellodendri, Herba Leonuri, Fructus Schisandrae Chinensis, Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Scutellariae, Herba Menthae, Rhizoma Chuanxiong, Fructus Atriplicis Sibiricae, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, the Fructus Kochiae, Ramulus Mori, add water, decoct, at a simmer the military decocting of front employing boils, and adopts slow fire boiling 20-40 minute after boiling; Filter, retain filtrate, add water in filtering residue, intense fire boils, then adds water, after water boils, decocts 10-30 minute, merges the filtrate of twice.
In the preparation of Chinese medicine composition for the treatment of skin pruritus, the 3-4 that twice amount of water is raw material dose doubly.
Preferably, the preparation method of the compositions for the treatment of skin pruritus, comprises following step:
Get Herba Houttuyniae, Radix Sophorae Flavescentis, Cortex Magnoliae Officinalis, Cortex Phellodendri, Herba Leonuri, Fructus Schisandrae Chinensis, Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Scutellariae, Herba Menthae, Rhizoma Chuanxiong, Fructus Atriplicis Sibiricae, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, the Fructus Kochiae, Ramulus Mori, add water, decoct, at a simmer the military decocting of front employing boils, and adopts slow fire boiling 25-35 minute after boiling; Filter, retain filtrate, add water in filtering residue, intense fire boils, then adds water, after water boils, decocts 15-25 minute, merges the filtrate of twice.
Preferred, the preparation method of the compositions for the treatment of skin pruritus, comprises following step:
Get Herba Houttuyniae, Radix Sophorae Flavescentis, Cortex Magnoliae Officinalis, Cortex Phellodendri, Herba Leonuri, Fructus Schisandrae Chinensis, Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Scutellariae, Herba Menthae, Rhizoma Chuanxiong, Fructus Atriplicis Sibiricae, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, the Fructus Kochiae, Ramulus Mori, add water, decoct, at a simmer the military decocting of front employing boils, and adopts slow fire boiling 30 minutes after boiling; Filter, retain filtrate, add water in filtering residue, intense fire boils, then adds water, after water boils, decocts 20 minutes, merges the filtrate of twice.
Herba Houttuyniae cold nature, bitter in the mouth, has heat-clearing and toxic substances removing, the effects such as inducing diuresis to remove edema.Cure mainly pneumonia, lung abscess, hematodiarrhoea, malaria, edema, gonorrhea, leucorrhea, carbuncle, hemorrhoid, proctoptosis, eczema, tinea alba, scabies.
Cortex Phellodendri is the dry bark of rutaceae wampee or Cortex Phellodendri.The former practises title " Cortex Phellodendri ", and the latter practises title " Cortex Phellodendri ".Can be used as medicine, nature and flavor bitter cold, has heat clearing and damp drying, and pathogenic fire purging is except steaming, the effect of detoxification sore treatment.Cortex Phellodendri is distributed in the areas such as Northeast China and each province, North China, and happiness grows among mountain area, assorted woods, and strong adaptability is applicable to sun-drenched local cultivation, also can anti-severe cold.Cortex Phellodendri is conventional Chinese medicine, its cold in nature, bitter in the mouth, and the effects such as tool heat clearing and damp drying, eliminating fire and detoxication, are usually used in the diseases such as damp-heat dysentery, jaundice, leucorrhea and pyretic arthralgia, pyretic stranguria.Modern study shows, Cortex Phellodendri is containing main components such as berberine, obacunone, have antibacterial, convergence, antiinflammatory etc. effect.
Herba Leonuri is the herb of labiate Herba Leonuri.1 year or biennial herb, summer-flowering.Be born in hill wasteland, ridge, meadow etc.All there is distribution most areas, the whole nation.When the colored not standard-sized sheet of riotous growth in summer, pluck.Edible effect: acrid in the mouth is bitter, cool.Invigorate blood circulation, dispel silt, regulating menstruation, water disappears.Treatment menoxenia, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.
Radix Scutellariae another name Radix Scutellariae, tsuchikane tea root.Radix Scutellariae is a kind of plant of Labiatae Scutellaria, belongs to half kind kind of semi-wild, herbaceos perennial.The root of Radix Scutellariae is a kind of medical herbs, bitter in the mouth, cold in nature, energy heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.The clinical practice of Radix Scutellariae is antibacterial not worse than Rhizoma Coptidis, and does not develop immunity to drugs.We are used in fungal culture miscellaneous bacteria and infect special severity by the strong feature of broad-spectrum antibacterial action, and fine by Radix Scutellariae extracting solution effect, it is that agricultural disease is prevented and treated optimal a herb.
Rhizoma Chuanxiong is perennial herb, high 40-60 centimetre, and rhizome is flourishing, forms irregular nodositas fist shape agglomerate, the strong fragrance of tool.The florescence 7-8 month, the young fruit period 9-10 month.Rhizoma Chuanxiong is a kind of Chinese medicinal plant, is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, the pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go loose, the up top, mountain peak that reaches; Enter again blood system, the descending sea of blood that reaches.Blood circulation promoting and blood stasis dispelling effect is extensive, the various diseases of suitable stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.It is the gas medicine in blood that former times people calls Rhizoma Chuanxiong, nearly says the functions such as pungent loose, the resolving depression of its residence, sensible, pain relieving.The pungent temperature rise of this product is loose, and all hyperactivity of YANG due to deficiency of YIN and excessive rising of liver-YANG person should not apply; Menorrhagia, anemia of pregnant woman also avoid use.
Radix Cynanchi Paniculati is pungent, temperature.Return Liver Channel, stomach warp.Function is the removing dampness of dispeling the wind, antalgesic-antipruritic.Cure mainly for rheumatic arthralgia stomachache distension, toothache, lumbago, injury from falling down, urticaria, eczema.
Pharmacology analysis: the Herba Houttuyniae in side's medicine of the present invention has the effect of heat-clearing and toxic substances removing, Fructus Schisandrae Chinensis has the effect of astringent or styptic treatment for spontaneous sweating, the supplementing QI for promoting the production of body fluid of convergence, kidney calming, the effect that the Radix Paeoniae Alba has clear and coherent blood vessels, nourishing blood to suppress the hyperactive liver, holds back juice in slow; The effect that Radix Saposhnikoviae has that Eradicates wind only induces sweat, removing dampness to relieve pain, relieving convulsion are jerked surely; Herba Menthae has the effect of dispelling wind and heat pathogens, clear profit removing toxic substances, dispersing the stagnated live-QI to relieve the stagnation of QI, and above all medical instruments have that heat-clearing and toxic substances removing, clear and coherent blood vessels, Eradicates wind are antipruritic, the effect of nourishing the liver and kidney.
Beneficial effect of the present invention is, adopts above-mentioned formula and method to prepare the medicine of resulting treatment skin pruritus, and compound method is easy, the wide material sources of crude drug, and also cost is low.Follow the prescriptions principle of the traditional Chinese medical science, adopt the use that is decocted in water for oral dose, through clinical difficulty, it is evident in efficacy, reliable effect, and the property of medicine is gentle, has no side effect, and effective percentage reaches more than 95%, and cure rate reaches 75%.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
By above-mentioned parts by weight, get Herba Houttuyniae, Radix Sophorae Flavescentis, Cortex Magnoliae Officinalis, Cortex Phellodendri, Herba Leonuri, Fructus Schisandrae Chinensis, Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Scutellariae, Herba Menthae, Rhizoma Chuanxiong, Fructus Atriplicis Sibiricae, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, the Fructus Kochiae, Ramulus Mori, add water, decoct, at a simmer the military decocting of front employing boils, and adopts slow fire boiling 30 minutes after boiling; Filter, retain filtrate, add water in filtering residue, intense fire boils, then adds water, after water boils, decocts 20 minutes, merges the filtrate of twice.
The clinical observation for the treatment of by Chinese herbs skin pruritus of the present invention.
Physical data
Clinical observation case is totally 100 examples, male 50 examples wherein, and female's 50 examples, age 20-40 year 30 examples, 40-50 year 30 examples,
50-60 year 30 examples, 60 years old above 10 example.
Diagnostic criteria
General skin pruritus: whole body skin is itched without fixed place or general property skin pruritus, and attach most importance to night, xerosis cutis, scratch is obvious.Limitation skin pruritus: gargalesthesia is confined to a certain position of health more, as anus, cysthus, scrotum etc. are located, affected part by
In long-term pruritus, see and infiltrate plumpness, lichen sample becomes and eczematization.Deficiency of YIN wind is contained disease diagnosis: primary symptom: 1, skin pruritus, becoming severe at night and/or rise one after another; 2, red tongue or partially red, Artemusia lactiflora Wall. or flower stripping; 3, skin is scorching hot and/or dry.Inferior disease: 1, scratch is innumerable or be lichen sample and become; 2, dysphoria with smothery sensation; 3, dry throat and mouth; 4, difficulty in defecation; 5, stringy and thready pulse or stringy and thready pulse number.
Method
1 dose of every day, sooner or later each is cleaned once, cleans ten minutes at every turn, and direct scouring skin after medicine heating that can be above-mentioned is cleaned skin after also above-mentioned medicine can being converted to hot water, within 15 days, is 1 course for the treatment of, 2-3 the course for the treatment of.
Efficacy assessment standard
Clinical recovery: pruritus disappears completely, other clinical pathological changes transference cures.
Effective: pruritus symptom disappears substantially, secondary skin obviously improves.Effective: pruritus alleviates, meeting inducement by chance has endurable gargalesthesia, and diseased region dwindles, and it is light red or red that skin is; Secondary skin lesion makes moderate progress.Invalid: pruritus and secondary skin lesion improve not obvious.
Efficacy result 75 examples of fully recovering account for 75%, and effective 95 examples account for 95%, and total effective rate reaches 95%.
Embodiment 2
By above-mentioned parts by weight, get Herba Houttuyniae, Radix Sophorae Flavescentis, Cortex Magnoliae Officinalis, Cortex Phellodendri, Herba Leonuri, Fructus Schisandrae Chinensis, Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Scutellariae, Herba Menthae, Rhizoma Chuanxiong, Fructus Atriplicis Sibiricae, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, the Fructus Kochiae, Ramulus Mori, add water, decoct, at a simmer the military decocting of front employing boils, and adopts slow fire boiling 30 minutes after boiling; Filter, retain filtrate, add water in filtering residue, intense fire boils, then adds water, after water boils, decocts 20 minutes, merges the filtrate of twice.
Embodiment 3
By above-mentioned parts by weight, get Herba Houttuyniae, Radix Sophorae Flavescentis, Cortex Magnoliae Officinalis, Cortex Phellodendri, Herba Leonuri, Fructus Schisandrae Chinensis, Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Scutellariae, Herba Menthae, Rhizoma Chuanxiong, Fructus Atriplicis Sibiricae, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, the Fructus Kochiae, Ramulus Mori, add water, decoct, at a simmer the military decocting of front employing boils, and adopts slow fire boiling 20 minutes after boiling; Filter, retain filtrate, add water in filtering residue, intense fire boils, then adds water, after water boils, decocts 10 minutes, merges the filtrate of twice.
Embodiment 4
By above-mentioned parts by weight, get Herba Houttuyniae, Radix Sophorae Flavescentis, Cortex Magnoliae Officinalis, Cortex Phellodendri, Herba Leonuri, Fructus Schisandrae Chinensis, Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Scutellariae, Herba Menthae, Rhizoma Chuanxiong, Fructus Atriplicis Sibiricae, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, the Fructus Kochiae, Ramulus Mori, add water, decoct, at a simmer the military decocting of front employing boils, and adopts slow fire boiling 40 minutes after boiling; Filter, retain filtrate, add water in filtering residue, intense fire boils, then adds water, after water boils, decocts 30 minutes, merges the filtrate of twice.
Claims (8)
1. a Chinese medicine composition for the treatment of skin pruritus, is characterized in that, described Chinese medicine composition comprises the component of following portions by weight:
2. a kind of Chinese medicine composition for the treatment of skin pruritus as claimed in claim 1, is characterized in that, described Chinese medicine composition comprises the component of following portions by weight:
3. a kind of Chinese medicine composition for the treatment of skin pruritus as claimed in claim 1, is characterized in that, described Chinese medicine composition comprises the component of following portions by weight:
4. a kind of Chinese medicine composition for the treatment of skin pruritus as claimed in claim 1, is characterized in that, described Chinese medicine composition comprises the component of following portions by weight:
5. a kind of preparation method for the treatment of the Chinese medicine composition of skin pruritus as claimed in claim 1, comprises following step:
By following parts by weight, get Herba Houttuyniae 5-12, Radix Sophorae Flavescentis 5-15, Cortex Magnoliae Officinalis 5-15, Cortex Phellodendri 5-15, Herba Leonuri 2-8, Fructus Schisandrae Chinensis 3-10, Radix Saposhnikoviae 2-10, Radix Paeoniae Alba 2-8, Radix Scutellariae 1-7, Herba Menthae 2-8, Rhizoma Chuanxiong 1-10, Fructus Atriplicis Sibiricae 1-6, Radix Cynanchi Paniculati 1-6, Radix Angelicae Dahuricae 1-8, Fructus Kochiae 5-10, Ramulus Mori 2-8, add water, decoct, at a simmer, adopt military decocting to boil, after boiling, adopt slow fire boiling 20-40 minute; Filter, retain filtrate, add water in filtering residue, intense fire boils, then adds water, after water boils, decocts 10-30 minute, merges the filtrate of twice.
6. a kind of preparation method for the treatment of the Chinese medicine composition of skin pruritus as claimed in claim 1, is characterized in that, twice described amount of water is 3-4 times of raw material dose.
7. a kind of preparation method for the treatment of the Chinese medicine composition of skin pruritus as claimed in claim 1, it is characterized in that, by following parts by weight, get Herba Houttuyniae 5-12, Radix Sophorae Flavescentis 5-15, Cortex Magnoliae Officinalis 5-15, Cortex Phellodendri 5-15, Herba Leonuri 2-8, Fructus Schisandrae Chinensis 3-10, Radix Saposhnikoviae 2-10, Radix Paeoniae Alba 2-8, Radix Scutellariae 1-7, Herba Menthae 2-8, Rhizoma Chuanxiong 1-10, Fructus Atriplicis Sibiricae 1-6, Radix Cynanchi Paniculati 1-6, Radix Angelicae Dahuricae 1-8, Fructus Kochiae 5-10, Ramulus Mori 2-8, add water, decoct, at a simmer, adopt military decocting to boil, after boiling, adopt slow fire boiling 25-35 minute; Filter, retain filtrate, add water in filtering residue, intense fire boils, then adds water, after water boils, decocts 15-25 minute, merges the filtrate of twice.
8. a kind of preparation method for the treatment of the Chinese medicine composition of skin pruritus as claimed in claim 1, it is characterized in that, by following parts by weight, get Herba Houttuyniae 5-12, Radix Sophorae Flavescentis 5-15, Cortex Magnoliae Officinalis 5-15, Cortex Phellodendri 5-15, Herba Leonuri 2-8, Fructus Schisandrae Chinensis 3-10, Radix Saposhnikoviae 2-10, Radix Paeoniae Alba 2-8, Radix Scutellariae 1-7, Herba Menthae 2-8, Rhizoma Chuanxiong 1-10, Fructus Atriplicis Sibiricae 1-6, Radix Cynanchi Paniculati 1-6, Radix Angelicae Dahuricae 1-8, Fructus Kochiae 5-10, Ramulus Mori 2-8, add water, decoct, at a simmer, adopt military decocting to boil, after boiling, adopt slow fire boiling 30 minutes; Filter, retain filtrate, add water in filtering residue, intense fire boils, then adds water, after water boils, decocts 20 minutes, merges the filtrate of twice.
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| CN104161879A (en) * | 2014-08-10 | 2014-11-26 | 庞金萍 | Traditional Chinese medicine cream capable of accelerating wound healing of patients with tuberculosis and preparation method of traditional Chinese medicine cream |
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