CN103623088A - Ephedra, almond gypsum and licorice granule pill - Google Patents
Ephedra, almond gypsum and licorice granule pill Download PDFInfo
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- CN103623088A CN103623088A CN201310644894.3A CN201310644894A CN103623088A CN 103623088 A CN103623088 A CN 103623088A CN 201310644894 A CN201310644894 A CN 201310644894A CN 103623088 A CN103623088 A CN 103623088A
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Abstract
The invention discloses an ephedra, almond gypsum and licorice granule pill. The ephedra, almond gypsum and licorice granule pill comprises a base pill (1) as the core, a medicine layer (2) obtained by mixing ephedra, almond gypsum and licorice granules, monoglyceride, hydroxy propyl methyl cellulose and acrylic resin, a coating layer (3) and a color coating layer (4), wherein the base pill (1) is coated with the medicine layer (2); the polymer slow-release coating layer (3) and the color coating layer (4) are sequentially coated layer by layer outwards. The invention solves the problems that ephedra, almond gypsum and licorice granules are short in half-life period and more frequent in administration, and makes up the shortfall in the prior art.
Description
Technical field
Invention relates to a kind of Maxingshigan granular pill.
Background technology
By traditional method, prepare long-acting Maxingshigan granule cost too high, main cause is the characteristic of Maxingshigan granule itself.Maxingshigan granule is made by Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, the above four taste Chinese medicines of Radix Glycyrrhizae, has the effect of removing heat-phlegm, relieving cough and asthma.This product granulation can overcome the oral difficulty of Chinese medicine, and drug effect is good, is applicable to extensive administration.
Summary of the invention
The object of invention is to provide a kind of Maxingshigan granular pill, and invention has solved the problem that the Maxingshigan granule half-life is short, administration number of times is many, has made up the deficiencies in the prior art.
The technical problem that will solve required for the present invention, can be achieved through the following technical solutions:
A Maxingshigan granular pill, is characterized in that: be followed successively by from inside to outside: as the base ball of core, and Maxingshigan granule, monoglyceride, hydroxypropyl emthylcellulose (HPMC) and the acrylic resin medicine layer, coatings and the color clothing layer that mix.
Further, described base ball adopts starch to make spherical or olive shape structure.
Further, according to ratio of weight and number meter, the ratio by Maxingshigan granule, monoglyceride, hydroxypropyl emthylcellulose (HPMC) and acrylic resin in described medicine layer is that 1 ~ 10:1 ~ 10:1 ~ 10:1 ~ 10 are coated on outside base ball, makes spherical or olive shape structure.
Further, according to ratio of weight and number meter, described coatings is by polyacrylic resin 50 ~ 60, Pulvis Talci 8 ~ 10, and triethyl citrate 1 ~ 2, water 30 ~ 40 is coated on outside medicine layer, makes spherical or olive shape structure.
Further, described Maxingshigan granule mixes the dry chondritic of making by Maxingshigan granule by Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, Radix Glycyrrhizae, the diameter of this chondritic is 0.1 ~ 1mm, according to ratio of weight and number meter, Maxingshigan granule is 1 ~ 10:1 ~ 20:1 ~ 10:1 ~ 30 by Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, Radix Glycyrrhizae.
Further, described color clothing layer adopts food coloring to be coated on outside coatings, makes spherical or olive shape structure.
Further, the diameter of described base ball is about 0.1mm; The thickness of described medicine layer is about 0.3mm; The thickness of described coatings is about 0.1mm; The thickness of described color clothing layer is about 0.05mm.
Pharmacological action:
The ability of penetration cell wall is strong, can anti-bacteria cell membrane synthetic, make antibacterial become spheroid and dissolvings of breaking rapidly, thus to the bactericidal action of various bacteria compared with rapidly and by force.
Indication: for poultry escherichia coli, Salmonella, streptococcus, the caused enteritis such as Bacillus proteus and pasteurellosis bacillus, diarrhoea, salpingitis, oophoritis, the mould unrest of fowl, injury flu, bronchitis, pneumonia, the diseases such as mycoplasma infection.
Consumption usage:
Mixed drink, every 50 grams of this product are converted 200L water and are drunk for poultry.
Mixed feeding, every 100g Maxingshigan granule.
Calomelas: be general processing technique, product for animals is all used Calomelas to be dissolved in water, drinks to beast.
Heavy powder: be through compacting, granulate, mixed powder, the particle size distribution that the physical process such as sieve obtains reaches necessarily required product, and heavy powder can be directly encapsulated.
Beneficial effect of the present invention:
A kind of Maxingshigan long-acting granular granular pill of invention, adopt Maxingshigan granule and blocker mixing granulation to realize slow release object, the Maxingshigan granule half-life of the present invention is 12 hours, and administration number of times is 12 hours/time, greatly save production cost, improved economic benefit.
Accompanying drawing explanation
Fig. 1 is structural representation of the present invention.
Reference numeral:
The 1st, base ball, the 2nd, medicine layer, the 3rd, coatings, the 4th, color clothing layer.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is done to progressive explanation.Should be understood that following examples are only for the present invention is described but not for limiting scope of the present invention.
Fig. 1 is structural representation of the present invention, as shown in Figure 1, a kind of Maxingshigan granular pill, be followed successively by from inside to outside: as the base ball 1 of core, and the medicine layer 2 that mixes of Maxingshigan granule, monoglyceride, hydroxypropyl emthylcellulose HPMC and acrylic resin, coatings 3 and color clothing layer 4, coated layer by layer.
According to ratio of weight and number meter, the ratio by Maxingshigan granule, monoglyceride, hydroxypropyl emthylcellulose (HPMC) and acrylic resin in medicine layer 2 is that 1 ~ 10:1 ~ 10:1 ~ 10:1 ~ 10 are coated on outside base ball 1, makes spherical or olive shape structure.
Maxingshigan granule is mixed to be dried by Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, Radix Glycyrrhizae by Maxingshigan granule makes chondritic, and the diameter of this chondritic is 0.1 ~ 1mm.
According to ratio of weight and number meter, Maxingshigan granule is 1 ~ 10:1 ~ 20:1 ~ 10:1 ~ 30 by Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, Radix Glycyrrhizae.The thickness of medicine layer 2 is about 0.3mm.
According to ratio of weight and number meter, coatings 3 is by polyacrylic resin 50 ~ 60, Pulvis Talci 8 ~ 10, and triethyl citrate 1 ~ 2, water 30 ~ 40 is coated on outside medicine layer 2, makes spherical or olive shape structure.The thickness of coatings 3 is about 0.1mm.
Color clothing layer 4 adopts food coloring to be coated on outside coatings 3, makes spherical or olive shape structure.The thickness of color clothing layer 4 is about 0.05mm.
Through evidence, a kind of Maxingshigan granular pill of invention has solved the problem that the Maxingshigan granule half-life is short, administration number of times is many really, has made up the deficiencies in the prior art.
Above the specific embodiment of the present invention is illustrated, but the present invention is as limit, only otherwise depart from aim of the present invention, the present invention can also have various variations.
Claims (7)
1. a Maxingshigan granular pill, it is characterized in that: be followed successively by from inside to outside: as the base ball (1) of core, and Maxingshigan granule, monoglyceride, hydroxypropyl emthylcellulose and the acrylic resin medicine layer (2), coatings (3) and the color clothing layer (4) that mix.
2. pill according to claim 1, is characterized in that: described base ball (1) adopts starch to make spherical or olive shape structure.
3. pill according to claim 1, it is characterized in that: according to ratio of weight and number meter, ratio by Maxingshigan granule, monoglyceride, hydroxypropyl emthylcellulose (HPMC) and acrylic resin in described medicine layer (2) is that 1 ~ 10:1 ~ 10:1 ~ 10:1 ~ 10 are coated on outside base ball (1), makes spherical or olive shape structure.
4. pill according to claim 1, is characterized in that: according to ratio of weight and number meter, described coatings (3) is by polyacrylic resin 50 ~ 60, Pulvis Talci 8 ~ 10, triethyl citrate 1 ~ 2, water 30 ~ 40 is coated on outside medicine layer (2), makes spherical or olive shape structure.
5. pill according to claim 4, it is characterized in that: described Maxingshigan granule mixes the dry chondritic of making by Maxingshigan granule by Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, Radix Glycyrrhizae, the diameter of this chondritic is 0.1 ~ 1mm, according to ratio of weight and number meter, Maxingshigan granule is 1 ~ 10:1 ~ 20:1 ~ 10:1 ~ 30 by Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, Radix Glycyrrhizae.
6. pill according to claim 1, is characterized in that: described color clothing layer (4) adopts food coloring to be coated on outside coatings (3), makes spherical or olive shape structure.
7. pill according to claim 1, is characterized in that: the diameter of described base ball (1) is about 0.1mm; The thickness of described medicine layer (2) is about 0.3mm; The thickness of described coatings (3) is about 0.1mm; The thickness of described color clothing layer (4) is about 0.05mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310644894.3A CN103623088A (en) | 2013-12-05 | 2013-12-05 | Ephedra, almond gypsum and licorice granule pill |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310644894.3A CN103623088A (en) | 2013-12-05 | 2013-12-05 | Ephedra, almond gypsum and licorice granule pill |
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| CN103623088A true CN103623088A (en) | 2014-03-12 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201310644894.3A Pending CN103623088A (en) | 2013-12-05 | 2013-12-05 | Ephedra, almond gypsum and licorice granule pill |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104435216A (en) * | 2014-11-26 | 2015-03-25 | 黑龙江省智诚医药科技有限公司 | Ephedra and apricot cough relieving traditional Chinese medicine dispersible tablet and preparation method thereof |
| CN106334009A (en) * | 2016-08-30 | 2017-01-18 | 林州中农颖泰生物肽有限公司 | Herba ephedrae-bitter apricot kernel-gypsum-licorice root effervescent granules and preparation method thereof |
| CN112516259A (en) * | 2020-12-10 | 2021-03-19 | 新疆医科大学第一附属医院 | Pharmaceutical composition for treating pneumonia and preparation method thereof |
| CN112656850A (en) * | 2021-01-11 | 2021-04-16 | 四川恒通动保生物科技有限公司 | Veterinary ephedra, apricot kernel, gypsum and licorice sustained-release granules and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1724019A (en) * | 2005-07-04 | 2006-01-25 | 陈学锋 | Medicine for relieving-cough and asthma |
| CN201426857Y (en) * | 2009-07-13 | 2010-03-24 | 上海恒丰强动物药业有限公司 | Amoxicillin long-acting granular pill |
| CN101810699A (en) * | 2009-12-17 | 2010-08-25 | 河南省康星药业有限公司 | Preparation method of Maxingshigan submicron powder |
-
2013
- 2013-12-05 CN CN201310644894.3A patent/CN103623088A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1724019A (en) * | 2005-07-04 | 2006-01-25 | 陈学锋 | Medicine for relieving-cough and asthma |
| CN201426857Y (en) * | 2009-07-13 | 2010-03-24 | 上海恒丰强动物药业有限公司 | Amoxicillin long-acting granular pill |
| CN101810699A (en) * | 2009-12-17 | 2010-08-25 | 河南省康星药业有限公司 | Preparation method of Maxingshigan submicron powder |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104435216A (en) * | 2014-11-26 | 2015-03-25 | 黑龙江省智诚医药科技有限公司 | Ephedra and apricot cough relieving traditional Chinese medicine dispersible tablet and preparation method thereof |
| CN106334009A (en) * | 2016-08-30 | 2017-01-18 | 林州中农颖泰生物肽有限公司 | Herba ephedrae-bitter apricot kernel-gypsum-licorice root effervescent granules and preparation method thereof |
| CN112516259A (en) * | 2020-12-10 | 2021-03-19 | 新疆医科大学第一附属医院 | Pharmaceutical composition for treating pneumonia and preparation method thereof |
| CN112656850A (en) * | 2021-01-11 | 2021-04-16 | 四川恒通动保生物科技有限公司 | Veterinary ephedra, apricot kernel, gypsum and licorice sustained-release granules and preparation method thereof |
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Application publication date: 20140312 |