CN103620476A - 生物成像的图像质量优化 - Google Patents

生物成像的图像质量优化 Download PDF

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Publication number
CN103620476A
CN103620476A CN201280032291.1A CN201280032291A CN103620476A CN 103620476 A CN103620476 A CN 103620476A CN 201280032291 A CN201280032291 A CN 201280032291A CN 103620476 A CN103620476 A CN 103620476A
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CN
China
Prior art keywords
image
image quality
biological
background
microscope
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201280032291.1A
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English (en)
Chinese (zh)
Inventor
P.A.福米乔夫
W.布拉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Global Life Sciences Solutions USA LLC
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GE Healthcare Bio Sciences Corp
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Publication date
Application filed by GE Healthcare Bio Sciences Corp filed Critical GE Healthcare Bio Sciences Corp
Publication of CN103620476A publication Critical patent/CN103620476A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008—Details of detection or image processing, including general computer control
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Health & Medical Sciences (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CN201280032291.1A 2011-06-30 2012-06-27 生物成像的图像质量优化 Pending CN103620476A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161503072P 2011-06-30 2011-06-30
US61/503,072 2011-06-30
PCT/SE2012/050720 WO2013002720A1 (en) 2011-06-30 2012-06-27 Image quality optimization of biological imaging

Publications (1)

Publication Number Publication Date
CN103620476A true CN103620476A (zh) 2014-03-05

Family

ID=47424393

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280032291.1A Pending CN103620476A (zh) 2011-06-30 2012-06-27 生物成像的图像质量优化

Country Status (5)

Country Link
US (1) US20140152800A1 (https=)
EP (1) EP2726931A4 (https=)
JP (1) JP2014521114A (https=)
CN (1) CN103620476A (https=)
WO (1) WO2013002720A1 (https=)

Cited By (1)

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CN108351523A (zh) * 2015-11-06 2018-07-31 欧库勒斯虚拟现实有限责任公司 利用头戴式显示器使用立体照相机以及结构光的深度映射

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US10025479B2 (en) * 2013-09-25 2018-07-17 Terarecon, Inc. Advanced medical image processing wizard
EP3508134B1 (en) 2014-01-02 2020-11-04 Koninklijke Philips N.V. Instrument alignment and tracking with ultrasound imaging plane
DE102016111938B4 (de) * 2016-06-29 2023-06-29 Leica Microsystems Cms Gmbh Lasermikrodissektionsverfahren und Lasermikrodissektionssysteme
US20180045937A1 (en) * 2016-08-10 2018-02-15 Zeta Instruments, Inc. Automated 3-d measurement
AU2020271905B2 (en) * 2019-04-11 2025-01-09 Agilent Technologies, Inc. Deep learning based training of instance segmentation via regression layers
MX2021016073A (es) * 2019-12-31 2022-03-25 Illumina Inc Funcionalidad de enfoque automático en el análisis óptico de muestras.
WO2021232195A1 (en) * 2020-05-18 2021-11-25 Shanghai United Imaging Healthcare Co., Ltd. Systems and methods for image optimization
US12566323B2 (en) 2020-07-07 2026-03-03 Secretary, Department Of Biotechnology AI enabled selective raman spectrometry using microscopy for diagnosis and analysis of biological samples
EP4198601B1 (en) * 2021-12-16 2025-08-27 Leica Microsystems CMS GmbH Fluorescence microscope system and method
EP4273608A1 (en) * 2022-05-04 2023-11-08 Leica Microsystems CMS GmbH Automatic acquisition of microscopy image sets
WO2023248853A1 (ja) * 2022-06-20 2023-12-28 ソニーグループ株式会社 情報処理方法、情報処理装置、及び顕微鏡システム

Citations (4)

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US20030147133A1 (en) * 1999-12-31 2003-08-07 Johann Engelhardt Method and system for user guidance in scanning microscopy
US20040000639A1 (en) * 2002-06-29 2004-01-01 Leica Microsystems Heidelberg Gmbh Method for setting the system parameters of a scanning microscope
US20050046836A1 (en) * 2003-08-27 2005-03-03 Leica Microsystems Heidelberg Gmbh Method for separating fluorescence spectra of dyes present in a sample
US20100086189A1 (en) * 2008-10-07 2010-04-08 Xiaohui Wang Automated quantification of digital radiographic image quality

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WO1998055026A1 (en) * 1997-06-05 1998-12-10 Kairos Scientific Inc. Calibration of fluorescence resonance energy transfer in microscopy
DE19853407C2 (de) * 1998-11-19 2003-09-11 Leica Microsystems Verfahren zur Einstellung der Systemparameter eines konfokalen Laserscanmikroskops
JP2000295462A (ja) * 1999-02-04 2000-10-20 Olympus Optical Co Ltd 顕微鏡画像伝送システム
US6905881B2 (en) * 2000-11-30 2005-06-14 Paul Sammak Microbead-based test plates and test methods for fluorescence imaging systems
DE10150542B4 (de) * 2001-10-12 2007-03-29 Leica Microsystems Cms Gmbh Verfahren zur Fluoreszenzmikroskopie
US7421140B2 (en) * 2001-11-21 2008-09-02 Shraga Rottem Method and system for enhancing the quality of device images
CA2729607A1 (en) * 2008-07-23 2010-01-28 Jianwei Miao Incorporation of mathematical constraints in methods for dose reduction and image enhancement in tomography
US20100157086A1 (en) * 2008-12-15 2010-06-24 Illumina, Inc Dynamic autofocus method and system for assay imager
US8520920B2 (en) * 2009-11-11 2013-08-27 Siemens Corporation System for dynamically improving medical image acquisition quality

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030147133A1 (en) * 1999-12-31 2003-08-07 Johann Engelhardt Method and system for user guidance in scanning microscopy
US20040000639A1 (en) * 2002-06-29 2004-01-01 Leica Microsystems Heidelberg Gmbh Method for setting the system parameters of a scanning microscope
US20050046836A1 (en) * 2003-08-27 2005-03-03 Leica Microsystems Heidelberg Gmbh Method for separating fluorescence spectra of dyes present in a sample
US20100086189A1 (en) * 2008-10-07 2010-04-08 Xiaohui Wang Automated quantification of digital radiographic image quality

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108351523A (zh) * 2015-11-06 2018-07-31 欧库勒斯虚拟现实有限责任公司 利用头戴式显示器使用立体照相机以及结构光的深度映射
US10893260B2 (en) 2015-11-06 2021-01-12 Facebook Technologies, Llc Depth mapping with a head mounted display using stereo cameras and structured light

Also Published As

Publication number Publication date
EP2726931A4 (en) 2015-04-01
JP2014521114A (ja) 2014-08-25
EP2726931A1 (en) 2014-05-07
WO2013002720A1 (en) 2013-01-03
US20140152800A1 (en) 2014-06-05

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Application publication date: 20140305