CN103571800A - 一种去除疫苗中宿主dna的方法 - Google Patents
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- CN103571800A CN103571800A CN201210263908.2A CN201210263908A CN103571800A CN 103571800 A CN103571800 A CN 103571800A CN 201210263908 A CN201210263908 A CN 201210263908A CN 103571800 A CN103571800 A CN 103571800A
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- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
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- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32411—Hepatovirus, i.e. hepatitis A virus
- C12N2770/32434—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
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Claims (10)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210263908.2A CN103571800B (zh) | 2012-07-27 | 2012-07-27 | 一种去除疫苗中宿主dna的方法 |
PCT/CN2013/080119 WO2014015816A1 (zh) | 2012-07-27 | 2013-07-25 | 一种去除疫苗中宿主dna的方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201210263908.2A CN103571800B (zh) | 2012-07-27 | 2012-07-27 | 一种去除疫苗中宿主dna的方法 |
Publications (2)
Publication Number | Publication Date |
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CN103571800A true CN103571800A (zh) | 2014-02-12 |
CN103571800B CN103571800B (zh) | 2018-04-24 |
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CN201210263908.2A Active CN103571800B (zh) | 2012-07-27 | 2012-07-27 | 一种去除疫苗中宿主dna的方法 |
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CN (1) | CN103571800B (zh) |
WO (1) | WO2014015816A1 (zh) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105339495A (zh) * | 2013-07-11 | 2016-02-17 | 宝生物工程株式会社 | 制备无包膜病毒的方法 |
CN109806916A (zh) * | 2019-03-15 | 2019-05-28 | 中科森辉微球技术(苏州)有限公司 | 高性能阴离子交换介质及其制备方法 |
CN111249456A (zh) * | 2020-03-13 | 2020-06-09 | 武汉生物制品研究所有限责任公司 | 一种狂犬病病毒灭活疫苗的纯化方法 |
CN111575244A (zh) * | 2020-05-06 | 2020-08-25 | 江苏金迪克生物技术股份有限公司 | 一种低Vero细胞残留DNA狂犬病疫苗原液的制备方法 |
CN111979120A (zh) * | 2019-05-23 | 2020-11-24 | 比欧联科供应链管理(北京)有限公司 | 一种狂犬疫苗核酸消化去除装置及实验方法 |
CN114990162A (zh) * | 2022-07-18 | 2022-09-02 | 苏州吉纳星辰生物技术有限公司 | 一种降低aav病毒载体生产中质粒残留的方法 |
Citations (6)
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---|---|---|---|---|
WO1996027677A2 (en) * | 1995-03-07 | 1996-09-12 | Canji, Inc. | Method of purification of recombinant viral vectors containing a therapeutic gene |
CN101098959A (zh) * | 2004-10-22 | 2008-01-02 | 昂科利蒂克斯生物科技公司 | 改进的病毒纯化方法 |
CN101270350A (zh) * | 2008-03-05 | 2008-09-24 | 辽宁依生生物制药有限公司 | 一种提取狂犬病病毒的方法 |
CN101623497A (zh) * | 2009-08-05 | 2010-01-13 | 长春卫尔赛生物药业有限公司 | 一种狂犬病疫苗去除残余dna的方法 |
WO2012019354A1 (en) * | 2010-08-12 | 2012-02-16 | Yisheng Biopharma Holdings Ltd. | Method for reducing dna impurities in viral compositions |
WO2012041423A1 (de) * | 2010-09-28 | 2012-04-05 | Sartorius Stedim Biotech Gmbh | Verfahren zur abtrennung von viren aus einem kontaminanten enthaltenden flüssigen medium |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1718738A2 (en) * | 2004-02-23 | 2006-11-08 | Crucell Holland B.V. | Virus purification methods |
CN101638427B (zh) * | 2008-08-01 | 2014-03-05 | 上海泽润生物科技有限公司 | 一种病毒抗原的纯化方法 |
-
2012
- 2012-07-27 CN CN201210263908.2A patent/CN103571800B/zh active Active
-
2013
- 2013-07-25 WO PCT/CN2013/080119 patent/WO2014015816A1/zh active Application Filing
Patent Citations (6)
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WO1996027677A2 (en) * | 1995-03-07 | 1996-09-12 | Canji, Inc. | Method of purification of recombinant viral vectors containing a therapeutic gene |
CN101098959A (zh) * | 2004-10-22 | 2008-01-02 | 昂科利蒂克斯生物科技公司 | 改进的病毒纯化方法 |
CN101270350A (zh) * | 2008-03-05 | 2008-09-24 | 辽宁依生生物制药有限公司 | 一种提取狂犬病病毒的方法 |
CN101623497A (zh) * | 2009-08-05 | 2010-01-13 | 长春卫尔赛生物药业有限公司 | 一种狂犬病疫苗去除残余dna的方法 |
WO2012019354A1 (en) * | 2010-08-12 | 2012-02-16 | Yisheng Biopharma Holdings Ltd. | Method for reducing dna impurities in viral compositions |
WO2012041423A1 (de) * | 2010-09-28 | 2012-04-05 | Sartorius Stedim Biotech Gmbh | Verfahren zur abtrennung von viren aus einem kontaminanten enthaltenden flüssigen medium |
Non-Patent Citations (2)
Title |
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NEUZA M. FRAZATTI-GALLINAA,ET AL: "Vero-cell rabies vaccine produced using serum-free medium", 《VACCINE》 * |
WAGNER A. COSTA,ET AL: "Immunogenicity and safety of a new Vero cell rabies vaccine produced using serum-free medium", 《VACCINE》 * |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105339495A (zh) * | 2013-07-11 | 2016-02-17 | 宝生物工程株式会社 | 制备无包膜病毒的方法 |
CN109806916A (zh) * | 2019-03-15 | 2019-05-28 | 中科森辉微球技术(苏州)有限公司 | 高性能阴离子交换介质及其制备方法 |
CN109806916B (zh) * | 2019-03-15 | 2021-12-21 | 中科森辉微球技术(苏州)有限公司 | 高性能阴离子交换介质及其制备方法 |
CN111979120A (zh) * | 2019-05-23 | 2020-11-24 | 比欧联科供应链管理(北京)有限公司 | 一种狂犬疫苗核酸消化去除装置及实验方法 |
CN111979120B (zh) * | 2019-05-23 | 2022-09-27 | 比欧联科供应链管理(北京)有限公司 | 一种狂犬疫苗核酸消化去除装置及实验方法 |
CN111249456A (zh) * | 2020-03-13 | 2020-06-09 | 武汉生物制品研究所有限责任公司 | 一种狂犬病病毒灭活疫苗的纯化方法 |
CN111575244A (zh) * | 2020-05-06 | 2020-08-25 | 江苏金迪克生物技术股份有限公司 | 一种低Vero细胞残留DNA狂犬病疫苗原液的制备方法 |
CN111575244B (zh) * | 2020-05-06 | 2021-07-23 | 江苏金迪克生物技术股份有限公司 | 一种低Vero细胞残留DNA狂犬病疫苗原液的制备方法 |
CN114990162A (zh) * | 2022-07-18 | 2022-09-02 | 苏州吉纳星辰生物技术有限公司 | 一种降低aav病毒载体生产中质粒残留的方法 |
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Publication number | Publication date |
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WO2014015816A1 (zh) | 2014-01-30 |
CN103571800B (zh) | 2018-04-24 |
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