CN103550615B - 一种治疗脾肾两虚证型泄泻病的中药 - Google Patents
一种治疗脾肾两虚证型泄泻病的中药 Download PDFInfo
- Publication number
- CN103550615B CN103550615B CN201310540895.3A CN201310540895A CN103550615B CN 103550615 B CN103550615 B CN 103550615B CN 201310540895 A CN201310540895 A CN 201310540895A CN 103550615 B CN103550615 B CN 103550615B
- Authority
- CN
- China
- Prior art keywords
- parts
- grams
- radix
- spleen
- chinese medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims abstract description 22
- 239000003814 drug Substances 0.000 title claims abstract description 21
- 201000010099 disease Diseases 0.000 title claims abstract description 15
- 230000007812 deficiency Effects 0.000 title abstract description 12
- 238000009991 scouring Methods 0.000 title abstract 4
- 210000000952 spleen Anatomy 0.000 claims abstract description 34
- 210000003734 kidney Anatomy 0.000 claims abstract description 31
- 206010012735 Diarrhoea Diseases 0.000 claims abstract description 28
- 210000000582 semen Anatomy 0.000 claims abstract description 15
- 239000002994 raw material Substances 0.000 claims abstract description 3
- 208000011580 syndromic disease Diseases 0.000 claims description 19
- 206010003549 asthenia Diseases 0.000 claims description 18
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 8
- 241000628997 Flos Species 0.000 claims description 7
- 239000009636 Huang Qi Substances 0.000 claims description 7
- 241001489978 Eupolyphaga Species 0.000 claims description 6
- 241000131808 Scolopendra Species 0.000 claims description 6
- 230000000694 effects Effects 0.000 abstract description 7
- 238000010792 warming Methods 0.000 abstract description 6
- 241000045403 Astragalus propinquus Species 0.000 abstract description 3
- 235000006533 astragalus Nutrition 0.000 abstract description 3
- 229940079593 drug Drugs 0.000 abstract description 3
- 244000144730 Amygdalus persica Species 0.000 abstract description 2
- 241000382455 Angelica sinensis Species 0.000 abstract description 2
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract description 2
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract description 2
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract description 2
- 241000195954 Lycopodium clavatum Species 0.000 abstract description 2
- 241000237502 Ostreidae Species 0.000 abstract description 2
- 244000236658 Paeonia lactiflora Species 0.000 abstract description 2
- 235000008598 Paeonia lactiflora Nutrition 0.000 abstract description 2
- 244000274050 Platycodon grandiflorum Species 0.000 abstract description 2
- 235000006753 Platycodon grandiflorum Nutrition 0.000 abstract description 2
- 244000046146 Pueraria lobata Species 0.000 abstract description 2
- 230000001939 inductive effect Effects 0.000 abstract description 2
- 240000006766 Cornus mas Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 241000488974 Loranthus Species 0.000 abstract 1
- 235000006040 Prunus persica var persica Nutrition 0.000 abstract 1
- 235000010575 Pueraria lobata Nutrition 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 235000019606 astringent taste Nutrition 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 244000237330 gutta percha tree Species 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 235000020636 oyster Nutrition 0.000 abstract 1
- 230000003071 parasitic effect Effects 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 239000000047 product Substances 0.000 description 22
- 239000000796 flavoring agent Substances 0.000 description 20
- 235000019634 flavors Nutrition 0.000 description 20
- 239000008280 blood Substances 0.000 description 19
- 210000004185 liver Anatomy 0.000 description 19
- 210000004369 blood Anatomy 0.000 description 18
- 235000009508 confectionery Nutrition 0.000 description 10
- 208000002193 Pain Diseases 0.000 description 9
- 210000001015 abdomen Anatomy 0.000 description 9
- 210000003205 muscle Anatomy 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 210000000988 bone and bone Anatomy 0.000 description 7
- 201000000736 Amenorrhea Diseases 0.000 description 6
- 206010001928 Amenorrhoea Diseases 0.000 description 6
- 208000006820 Arthralgia Diseases 0.000 description 6
- 231100000540 amenorrhea Toxicity 0.000 description 6
- 210000004072 lung Anatomy 0.000 description 6
- 206010062717 Increased upper airway secretion Diseases 0.000 description 5
- 208000033809 Suppuration Diseases 0.000 description 5
- 208000026435 phlegm Diseases 0.000 description 5
- 231100000614 poison Toxicity 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 206010010774 Constipation Diseases 0.000 description 4
- 208000019255 Menstrual disease Diseases 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 208000002173 dizziness Diseases 0.000 description 4
- 210000003127 knee Anatomy 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 238000005728 strengthening Methods 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 230000035922 thirst Effects 0.000 description 4
- 206010007247 Carbuncle Diseases 0.000 description 3
- 206010011224 Cough Diseases 0.000 description 3
- 208000005171 Dysmenorrhea Diseases 0.000 description 3
- 206010013935 Dysmenorrhoea Diseases 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 208000008454 Hyperhidrosis Diseases 0.000 description 3
- 206010020772 Hypertension Diseases 0.000 description 3
- 206010030113 Oedema Diseases 0.000 description 3
- 208000025747 Rheumatic disease Diseases 0.000 description 3
- 208000009205 Tinnitus Diseases 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 230000001142 anti-diarrhea Effects 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 210000003414 extremity Anatomy 0.000 description 3
- 239000000706 filtrate Substances 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 239000012567 medical material Substances 0.000 description 3
- 230000001717 pathogenic effect Effects 0.000 description 3
- 230000000552 rheumatic effect Effects 0.000 description 3
- 206010040872 skin infection Diseases 0.000 description 3
- 231100000886 tinnitus Toxicity 0.000 description 3
- 208000008035 Back Pain Diseases 0.000 description 2
- 241000345998 Calamus manan Species 0.000 description 2
- 241001278898 Glycyrrhiza inflata Species 0.000 description 2
- 206010019233 Headaches Diseases 0.000 description 2
- 206010027514 Metrorrhagia Diseases 0.000 description 2
- 206010033557 Palpitations Diseases 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 208000005392 Spasm Diseases 0.000 description 2
- 241000800405 Spatholobus suberectus Species 0.000 description 2
- 208000012886 Vertigo Diseases 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 230000004064 dysfunction Effects 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 210000001624 hip Anatomy 0.000 description 2
- 208000013403 hyperactivity Diseases 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 210000000629 knee joint Anatomy 0.000 description 2
- 235000021374 legumes Nutrition 0.000 description 2
- 201000003453 lung abscess Diseases 0.000 description 2
- 201000007227 lymph node tuberculosis Diseases 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 230000036565 night sweats Effects 0.000 description 2
- 206010029410 night sweats Diseases 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 230000007096 poisonous effect Effects 0.000 description 2
- 206010037844 rash Diseases 0.000 description 2
- 235000012950 rattan cane Nutrition 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000002269 spontaneous effect Effects 0.000 description 2
- 230000035900 sweating Effects 0.000 description 2
- 210000002435 tendon Anatomy 0.000 description 2
- 231100000889 vertigo Toxicity 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 240000000031 Achyranthes bidentata Species 0.000 description 1
- 235000011446 Amygdalus persica Nutrition 0.000 description 1
- 241000208671 Campanulaceae Species 0.000 description 1
- 244000080208 Canella winterana Species 0.000 description 1
- 235000008499 Canella winterana Nutrition 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 244000020518 Carthamus tinctorius Species 0.000 description 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 235000021511 Cinnamomum cassia Nutrition 0.000 description 1
- 244000077995 Coix lacryma jobi Species 0.000 description 1
- 235000007354 Coix lacryma jobi Nutrition 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 241000142975 Cornaceae Species 0.000 description 1
- 241000759833 Cornus officinalis Species 0.000 description 1
- 241001427554 Corydiidae Species 0.000 description 1
- 241000548230 Crassostrea angulata Species 0.000 description 1
- 241001522252 Crassostrea rivularis Species 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 206010013952 Dysphonia Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000008967 Enuresis Diseases 0.000 description 1
- 241000208686 Eucommiaceae Species 0.000 description 1
- 241001489980 Eupolyphaga sinensis Species 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 206010018367 Glomerulonephritis chronic Diseases 0.000 description 1
- 240000008917 Glycyrrhiza uralensis Species 0.000 description 1
- 235000000554 Glycyrrhiza uralensis Nutrition 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 208000010473 Hoarseness Diseases 0.000 description 1
- 208000004044 Hypesthesia Diseases 0.000 description 1
- 241000221040 Loranthaceae Species 0.000 description 1
- 241000927897 Lycopodium japonicum Species 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- 208000019914 Mental Fatigue Diseases 0.000 description 1
- 206010062575 Muscle contracture Diseases 0.000 description 1
- 206010028836 Neck pain Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 241001523579 Ostrea Species 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 241000013557 Plantaginaceae Species 0.000 description 1
- 240000002381 Prunus davidiana Species 0.000 description 1
- 241000731396 Pueraria montana var. thomsonii Species 0.000 description 1
- 241000218201 Ranunculaceae Species 0.000 description 1
- 206010062104 Renal mass Diseases 0.000 description 1
- 241001334235 Scolopendra mutilans Species 0.000 description 1
- 241000131792 Scolopendridae Species 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 241000316341 Taxillus chinensis Species 0.000 description 1
- 206010043376 Tetanus Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 241000934136 Verruca Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010047601 Vitamin B1 deficiency Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 208000000260 Warts Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 239000003212 astringent agent Substances 0.000 description 1
- 208000002894 beriberi Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000000812 cholinergic antagonist Substances 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 208000006111 contracture Diseases 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 208000013219 diaphoresis Diseases 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 206010013990 dysuria Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 208000011318 facial edema Diseases 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 208000034783 hypoesthesia Diseases 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000004914 menses Anatomy 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 201000001474 proteinuria Diseases 0.000 description 1
- 235000021251 pulses Nutrition 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 230000005070 ripening Effects 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 201000010153 skin papilloma Diseases 0.000 description 1
- 230000002048 spasmolytic effect Effects 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 239000002435 venom Substances 0.000 description 1
- 210000001048 venom Anatomy 0.000 description 1
- 231100000611 venom Toxicity 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种治疗脾肾两虚证型泄泻病的中药，其特征是由下列重量配比的原料制成的：黄芪30份、当归15份、葛根24份、熟地黄30份、桃仁10份、红花20份、桂枝20份、土鳖虫10份、杜仲10份、牛膝15份、桑寄生15份、桔梗10份、甘草6份、炒白芍30份、牡蛎30份、蜈蚣1条、山茱萸15份、薏苡仁30份、伸筋草30份、鸡血藤30份。本发明的采用适宜的中药，各种药物之产是相互配合，协调作用，所制得的中药具有温肾健脾，温阳固涩止泻的功效，能有效治疗脾肾两虚证型泄泻病，五年来，通过对168名患者的使用表明，有效率达94%，治疗效果好，愈后不再复发。
Description
技术领域
本发明涉及一种中药，特别是一种用于治疗脾肾两虚证型泄泻病的中药。
背景技术
泄泻是指大便次数增多，粪便稀薄，甚至泻出如水样的病证。大便溏薄而势缓者为泄，大便清稀如水而直下者为泻。泄泻的证型有多种，如寒湿内证盛证型、湿热伤中证型、脾肾两虚证型等，脾肾两虚证型为常见的泄泻。目前治疗脾肾两虚证型泄泻病，西医一般只是单纯采用止泻类药，所以用药效果不好，而且只是治标不治本，即使有的患者当时被治好了，但过后很快就会复发，并且还有许多副作用，中医治疗泄泻病具有标本兼治的效果，而且副作用少，但目前还没有一种专用于治疗脾肾两虚证型泄泻病的中药。
发明内容
本发明旨在提供一种治疗脾肾两虚证型泄泻病的中药，通过选择合适的药材及其配比，达到安全有效治疗脾肾两虚证型泄泻病的目的。
为达到上述目的，本发明采用以下技术方案：一种治疗脾肾两虚证型泄泻病的中药，其特征是由下列重量配比的原料制成的：
黄芪30份、当归15份、葛根24份、熟地黄30份、桃仁10份、红花20份、桂枝20份、土鳖虫10份、杜仲10份、牛膝15份、桑寄生15份、桔梗10份、甘草6份、炒白芍30份、牡蛎30份、蜈蚣1条、山茱萸15份、薏苡仁30份、伸筋草30份、鸡血藤30份。
本发明配方中所述的各种药材的来源及功能主治如下：
黄芪【来源】 本品为豆科植物蒙古黄芪 Astragalus membranaceus （Fisch.） Bge. var. mongholicus （Bge.）Hsiao 或膜荚黄芪 Astragalus membranaceus （Fisch.） Bge.的干燥根。【性味】 甘，温。【归经】 归肺、脾经。【功能主治】 补气固表，利尿托毒，排脓，敛疮生肌。用于气虚乏力，食少便溏，中气下陷，久泻脱肛，便血崩漏，表虚自汗，气虚水肿，痈疽难溃，久溃不敛，血虚痿黄，内热消渴；慢性肾炎蛋白尿，糖尿病。
当归【来源】 本品为伞形科植物当归Angelica sinensis （Oliv.） Diels 的干燥根。【性味】 甘、辛，温。【归经】 归肝、心、脾经。
【功能主治】 补血活血，调经止痛，润肠通便。用于血虚萎黄，眩晕心悸，月经不调，经闭痛经，虚寒腹痛，肠燥便秘，风湿痹痛，跌扑损伤，痈疽疮疡。
葛根【来源】 本品为豆科植物野葛Pueraria lobata （Willd.）Ohwi或甘葛藤Pueraria thomsonii Benth.的干燥根。【性味】 甘、辛，凉。
【归经】 归脾、胃经。【功能主治】 解肌退热，生津，透疹，升阳止泻。用于外感发热头痛、项背强痛，口渴，消渴，麻疹不透，热痢，泄泻；高血压颈项强痛。
熟地黄【来源】 本品为玄参科植物地黄Rehmannia glutinosa Libosch. 的新鲜或干燥块根。炮制：本品为生地黄的炮制加工品。【性味】 甘，微温。【归经】 归肝、肾经。【功能主治】 滋阴补血，益精填髓。用于肝肾阴虚，腰膝酸软，骨蒸潮热，盗汗遗精，内热消渴，血虚萎黄，心悸怔忡，月经不调，崩漏下血，眩晕，耳鸣，须发早白。
桃仁【来源】 本品为蔷薇科植物桃Prunus persica （L.） Batsch 或山桃 Prunus davidiana （Carr.）Franch.的干燥成熟种子。【性味】 苦、甘，平。【归经】 归心、肝、大肠经。【功能主治】 活血祛瘀，润肠通便。用于经闭，痛经，癓瘕痞块，跌扑损伤，肠燥便秘。
红花【来源】 本品为菊科植物红花Carthamus tinctorius L.的干燥花。【性味】 辛，温。【归经】 归心、肝经。【功能主治】 活血通经，散瘀止痛。用于经闭，痛经，恶露不行，症瘕痞块，跌扑损伤，疮疡肿痛。
桂枝【来源】 本品为樟科植物肉桂 Cinnamomum cassia Presl的干燥嫩枝。【性味】 辛、甘，温。【归经】 归心、肺、膀胱经。【功能主治】 发汗解肌，温通经脉，助阳化气，平冲降气。用于风寒感冒，脘腹冷痛，血寒经闭，关节痹痛，痰饮，水肿，心悸，奔豚。
土鳖虫【来源】 本品为鳖蠊科昆虫地鳖Eupolyphaga sinensis Walker 或冀地鳖Steleophaga plancyi（Boleny）的雌虫干燥体。【性味】 咸，寒；有小毒。【归经】 归肝经。【功能主治】 破瘀血，续筋骨。用于筋骨折伤，瘀血经闭，症瘕痞块。
杜仲【来源】 药材基源：为杜仲科植物杜仲的叶。【性味】 微辛，性温。【归经】入肝，肾经。【功能主治】 补肝肾，强筋骨，降血压。主腰背疼痛，足膝酸软乏力，高血压病。
牛膝【来源】 本品为苋科植物牛膝Achyranthes bidentata Blume. 的干燥根。【性味】 苦、酸，平。【归经】 归肝、肾经。【功能主治】 补肝肾，强筋骨，逐瘀通经，引血下行。用于腰膝酸痛，筋骨无力，经闭症瘕，肝阳眩晕。
桑寄生【来源】 本品为桑寄生科植物桑寄生Taxillus chinensis （DC.）Danser 的干燥带叶茎枝。【性味】 苦、甘，平。【归经】 归肝、肾经。【功能主治】 补肝肾，强筋骨，祛风湿，安胎元。用于风湿痹痛，腰膝酸软，筋骨无力，崩漏经多，妊娠漏血，胎动不安；高血压。
桔梗【来源】 本品为桔梗科植物桔梗Platycodon grandiflorum（Jacq.）A.DC.的干燥根。【性味】 苦、辛，平。【归经】 归肺经。【功能主治】 宣肺，利咽，祛痰，排脓。用于咳嗽痰多，胸闷不畅，咽痛，音哑，肺痈吐脓，疮疡脓成不溃。
甘草【来源】 本品为豆科植物甘草 Glycyrrhiza uralensis Fisch.、胀果甘草 Glycyrrhiza inflata Bat. 或光果甘草 Glycyrrhiza glabra L. 的干燥根。【性味】 甘，平。【归经】 归心、肺、脾、胃经 。【功能主治】 补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
炒白芍【来源】 本品为毛茛科植物芍药Paeonia lactiflora Pall. 的干燥根。炒白芍：取净白芍片，锅内炒至微黄色。【性味】 苦、酸，微寒。【归经】 归肝、脾经。【功能主治】 平肝止痛，养血调经，敛阴止汗。用于头痛眩晕，胁痛，腹痛，四肢挛痛，血虚萎黄，月经不调，自汗，盗汗。
牡蛎【来源】 本品为牡蛎科动物长牡蛎Ostrea gigas Thunberg、大连湾牡蛎Ostrea talienwhanensis Crosse 或近江牡蛎Ostrea rivularis Gould的贝壳。【性味】 咸，微寒。【归经】 归肝、胆、肾经。【功能主治】 重镇安神，潜阳补阴，软坚散结。用于惊悸失眠，眩晕耳鸣，瘰疬痰核，症瘕痞块。
蜈蚣【来源】 本品为蜈蚣科动物少棘巨蜈蚣Scolopendra subspinipes mutilans L. Koch的干燥体。【性味】 辛，温；有毒。【归经】 归肝经。【功能主治】 息风镇痉，功毒散结，通络止痛。用于小儿惊风，抽搐痉挛，中风口歪，半身不遂，破伤风，风湿顽痹，疮疡，瘰疬，毒蛇咬伤。
山茱萸【来源】 本品为山茱萸科植物山茱萸Cornus officinalis Sieb. et Zucc. 的干燥成熟果肉。【性味】 酸、涩，微温。【归经】 归肝、肾经。【功能主治】 补益肝肾，涩精固脱。用于眩晕耳鸣，腰膝酸痛，阳痿遗精，遗尿尿频，崩漏带下，大汗虚脱。内热消渴。
薏苡仁【来源】 本品为禾本科植物薏苡Coix lacryma-jobi L. var. ma-yuen （Roman.）Stapf的干燥成熟种仁。【性味】 甘、淡，凉。【归经】 归脾、胃、肺经。【功能主治】 健脾渗湿，除痹止泻，清热排浓。用于水肿，脚气，小便不利，湿痹拘挛，脾虚泄泻，肺痈，肠痈；扁平疣。
伸筋草【来源】 本品为石松科植物石松Lycopodium japonicum Thunb. 的干燥全草。【性味】 微苦、辛，温。【归经】 归肝、脾、肾经。【功能主治】 祛风除湿，舒筋活络。用于关节酸痛，屈伸不利。
鸡血藤【来源】 本品为豆科植物密花豆（大血藤、血风藤、三叶鸡血藤、九层风）Spatholobus suberectus Dunn 的干燥藤茎。【性味】 苦、甘，温。【归经】 归肝、肾经。【功能主治】 补血，活血，通络。用于月经不调，血虚萎黄，麻木瘫痪，风湿痹痛。
中医认为：指肾阳不足，命门火衰，火不生土则脾失健运，清浊不分，气机升降失调，脾失温煦，运化失职，成为脾肾两脏阳气俱虚而致的泄泻。患者表现为形寒肢冷，腰膝酸软，大便稀溏，完谷不化，形体消瘦，神疲纳呆，面色少华，或面目虚浮，四肢欠温，舌淡苔白，脉细无力。本发明的采用适宜的中药，各种药物之产是相互配合，协调作用，所制得的中药具有温肾健脾，温阳固涩止泻的功效，能有效治疗脾肾两虚证型泄泻病，五年来，通过对168名患者的使用表明，有效率达94%，治疗效果好，愈后不再复发。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2008年4月-2013年5月间共收集了168例脾肾两虚证型泄泻病门诊患者，其中，男92例，女76例，年龄29-58岁，病情半个月-3年。随机分为：治疗组100例，对照组68例。两组年龄等资料无显著性差异，具有可比性。
2、试验方法
2.1对照组口服四神丸，按照说明书服用。疗程7天。
2.2治疗组口服本发明按照具体实施例1制得的胶囊，早、中、晚各一次。疗程7天。
3、疗效标准及治疗结果
3.1疗效标准：
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，病情得到控制，实验检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率（%） |
| 治疗组 | 100 | 32 | 62 | 6 | 94% |
| 空白组 | 68 | 9 | 30 | 29 | 57.4% |
由此可见，本发明制得的药物能够安全有效治疗脾肾两虚证型泄泻病。
具体实施方式
为了更好地理解与实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取黄芪30克、当归15克、葛根24克、熟地黄30克、桃仁10克、红花20克、桂枝20克、土鳖虫10克、杜仲10克、牛膝15克、桑寄生15克、桔梗10克、甘草6克、炒白芍30克、牡蛎30克、蜈蚣1条、山茱萸15克、薏苡仁30克、伸筋草30克、鸡血藤30克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗脾肾两虚证型泄泻病。口服，每日分早、中、晚三次服用。
具体实施例2
称取黄芪30克、当归15克、葛根24克、熟地黄30克、桃仁10克、红花20克、桂枝20克、土鳖虫10克、杜仲10克、牛膝15克、桑寄生15克、桔梗10克、甘草6克、炒白芍30克、牡蛎30克、蜈蚣1条、山茱萸15克、薏苡仁30克、伸筋草30克、鸡血藤30克，加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1.5小时，过滤；合并滤液，浓缩，干燥，包装，即得符合正常成人1天用量的散剂。
用于治疗脾肾两虚证型泄泻病。口服，每日分早、中、晚三次服用。
具体实施例3
称取黄芪30克、当归15克、葛根24克、熟地黄30克、桃仁10克、红花20克、桂枝20克、土鳖虫10克、杜仲10克、牛膝15克、桑寄生15克、桔梗10克、甘草6克、炒白芍30克、牡蛎30克、蜈蚣1条、山茱萸15克、薏苡仁30克、伸筋草30克、鸡血藤30克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即得符合正常成人1天用量的颗粒剂。
用于治疗脾肾两虚证型泄泻病。口服，每日分早、中、晚三次服用。
Claims (1)
1.一种治疗脾肾两虚证型泄泻病的中药，其特征是由下列重量配比的原料制成的：
黄芪30克、当归15克、葛根24克、熟地黄30克、桃仁10克、红花20克、桂枝20克、土鳖虫10克、杜仲10克、牛膝15克、桑寄生15克、桔梗10克、甘草6克、炒白芍30克、牡蛎30克、蜈蚣1条、山茱萸15克、薏苡仁30克、伸筋草30克、鸡血藤30克。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310540895.3A CN103550615B (zh) | 2013-11-06 | 2013-11-06 | 一种治疗脾肾两虚证型泄泻病的中药 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310540895.3A CN103550615B (zh) | 2013-11-06 | 2013-11-06 | 一种治疗脾肾两虚证型泄泻病的中药 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103550615A CN103550615A (zh) | 2014-02-05 |
| CN103550615B true CN103550615B (zh) | 2015-04-29 |
Family
ID=50005088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310540895.3A Expired - Fee Related CN103550615B (zh) | 2013-11-06 | 2013-11-06 | 一种治疗脾肾两虚证型泄泻病的中药 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103550615B (zh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107625930A (zh) * | 2017-10-13 | 2018-01-26 | 葛海霞 | 一种用于治疗腹泻的中药膏贴及其制备方法 |
| CN108434420A (zh) * | 2018-05-03 | 2018-08-24 | 甘肃中医药大学 | 一种用于治疗结直肠癌术后泄泻的中药制剂 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1334121A (zh) * | 2001-08-31 | 2002-02-06 | 石家庄以岭药业有限公司 | 一种通心络药物组合物及应用 |
| CN1457831A (zh) * | 2003-04-18 | 2003-11-26 | 侯增光 | 经络血管动力药 |
| CN101703692A (zh) * | 2009-11-05 | 2010-05-12 | 卢速江 | 一种治疗骨伤的中药制剂及其制备方法 |
-
2013
- 2013-11-06 CN CN201310540895.3A patent/CN103550615B/zh not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1334121A (zh) * | 2001-08-31 | 2002-02-06 | 石家庄以岭药业有限公司 | 一种通心络药物组合物及应用 |
| CN1457831A (zh) * | 2003-04-18 | 2003-11-26 | 侯增光 | 经络血管动力药 |
| CN101703692A (zh) * | 2009-11-05 | 2010-05-12 | 卢速江 | 一种治疗骨伤的中药制剂及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103550615A (zh) | 2014-02-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103520573B (zh) | 治疗肝郁血瘀证型乳癖病的中药 | |
| CN103599403B (zh) | 一种治疗偏头痛的中药组合物及其制备方法 | |
| CN104225166A (zh) | 一种治疗闭经的中药组合物及其制备方法 | |
| CN103550615B (zh) | 一种治疗脾肾两虚证型泄泻病的中药 | |
| CN103520571B (zh) | 治疗气滞血瘀证型癥瘕病的中药 | |
| CN103550608B (zh) | 一种治疗肝郁脾虚证型月经过少病的中药 | |
| CN103520673B (zh) | 治疗气血不足证型月经病的中药 | |
| CN103520570B (zh) | 治疗肝郁化火证型粉刺病的中药 | |
| CN103463519B (zh) | 治疗瘀阻脉络症型瘰疬病的中药 | |
| CN101926880A (zh) | 治疗妇女闭经及子宫内膜炎中药组合物 | |
| CN103536892B (zh) | 一种治疗阳虚寒凝证型不孕病的中药 | |
| CN104027597A (zh) | 一种治疗气虚血瘀证型血栓闭塞性脉管炎的中药 | |
| CN104771585A (zh) | 一种治疗急性肾炎的中药组合物及制备方法 | |
| CN103536863B (zh) | 一种治疗瘀血阻络证型不孕病的中药 | |
| CN103784720A (zh) | 一种降血糖尿糖的中药制剂 | |
| CN103623382B (zh) | 一种治疗漏肩风的中药 | |
| CN103505688B (zh) | 一种治疗肝胆湿热证型口糜病的中药 | |
| CN102861227B (zh) | 一种治疗化脓性脑膜炎后遗症的中药组合物及其制备方法 | |
| CN103463610B (zh) | 一种治疗营卫不和证型肌痹病的中药 | |
| CN105688074A (zh) | 一种治疗少腹痛的汤剂药物及其制备方法 | |
| CN103655789B (zh) | 一种治疗肝旺脾虚证型慢性结肠炎的中药 | |
| CN105250618A (zh) | 一种治疗肝硬化的抗病毒中药组合物及其制备方法 | |
| CN103655846B (zh) | 一种治疗胃络瘀阻证型胃下垂的中药 | |
| CN103520568B (zh) | 一种治疗气滞血瘀证型胸痹的中药 | |
| CN103550725B (zh) | 治疗风湿蕴肤证型水肿病的中药 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: QINGDAO MUNICIPAL HOSPITAL Free format text: FORMER OWNER: TAN QINWEN Effective date: 20150325 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| C53 | Correction of patent for invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Sun Hong Inventor after: Yu Hongyan Inventor after: Wang Ruirong Inventor after: Zhang Yan Inventor before: Tan Qinwen |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: TAN QINWEN TO: SUN HONG YU HONGYAN WANG RUIRONG ZHANG YAN Free format text: CORRECT: ADDRESS; FROM: 215101 SUZHOU, JIANGSU PROVINCE TO: 266011 QINGDAO, SHANDONG PROVINCE |
|
| TA01 | Transfer of patent application right |
Effective date of registration: 20150325 Address after: 266011 Jiaozhou Road, Shandong, China, No. 1, No. Applicant after: Qingdao Municipal Hospital Address before: Mudu Wuzhong District Jin Feng Road Suzhou city Jiangsu province 215101 No. 1258 building C Applicant before: Tan Qinwen |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150429 Termination date: 20161106 |