CN103463519B - 治疗瘀阻脉络症型瘰疬病的中药 - Google Patents
治疗瘀阻脉络症型瘰疬病的中药 Download PDFInfo
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Abstract
一种治疗瘀阻脉络症型瘰疬病的中药，其特征是由下列重量配比的药材制备而成：麻黄10份、连翘30份、赤芍15份、薏苡仁30份、升麻6份、当归10份、紫草10份、玄参12份、丹皮10份、黄芩10份、栀子10份、炒僵蚕10份、大黄10份、白芷10份、蜈蚣1条，甘草6份、牡蛎30份、炒王不留6份。按照本发明制得的中药具有化痰去瘀，软坚散结，活血通络，兼以清热解毒的功效，对治疗瘀阻脉络症型瘰疬病，具有十分显著的疗效。
Description
技术领域
本发明涉及一种中药，特别是一种用于治疗瘀阻脉络症型瘰疬病的中药。
背景技术
瘰疬是中医的名称，西医称为淋巴结核，老百姓称为老鼠疮。指发生于颈部、腋下等处的一种感染性外科疾病淋巴结。在颈部皮肉间可扪及大小不等的核块，互相串连，其中小者称瘰，大者称疬，统称瘰疬。该病的症状为：（1）初期：瘰疬初起如豆，单个或数个串生，不热不痛，皮色不变，推之能动，舌苔白，脉弦；（2）中期：瘰疬累累如串珠，皮核相亲，或融合成块，渐感疼痛，推之不移，或液化成脓，按之复指，舌苔薄黄，脉弦数；（3）后期：结核溃破，脓水清稀，久则成瘘，经久不愈，低热盗汗，咳嗽，舌红少苔，脉细数。引起该病的原因不外乎气郁、痰凝、血瘀、正虚所致，其中因血液瘀滞、经络受阻不通畅而导致的瘀阻脉络症型瘰疬病，在临床中比较常见。目前，治疗瘀阻脉络症型瘰疬病，有内服中药如瘰疬丸，也有采用西药治疗如异烟肼，链霉素、对氨基水杨酸钠联合使用，西药治疗不仅治疗时间长，而且副作用较大。中药治疗时间过长，治疗效果也不尽人意。
本发明的中药所涉及药材的研究现状如下：
麻黄【来源】本品为麻黄科植物草麻黄Ephedra sinica Stapf 、中麻黄Ephedra intermedia Schrenk et C. A. Mey. 或木贼麻黄Ephedra equisetina Bge.的干燥草质茎。秋季采割绿色的草质茎，晒干。【性味】辛、微苦，温。【归经】归肺、膀胱经。【功能主治】发汗散寒，宣肺平喘，利水消肿。用于风寒感冒，胸闷喘咳，风水浮肿，支气管哮喘，气喘咳嗽。
连翘【来源】本品为木犀科植物连翘Forsythia suspensa （Thunb.）Vahl的干燥果实。【性味】苦，微寒。【归经】归肺、心、小肠经。【功能主治】清热解毒，消肿散结。用于痈疽，瘰疠，乳痈，丹毒，风热感冒，温病初起，温热入营，高热烦渴，神昏发斑，热淋尿闭。
赤芍【来源】本品为毛茛科植物芍药Paeonia lactiflora Pall、或川赤芍Paeonia veitchii Lynch 的干燥根。【性味】： 苦，微寒。【归经】归肝经。【主治功效】：清热凉血；活血祛瘀。主温毒发斑，吐血衄血，肠风下血，目赤肿痛，痈肿疮疡，闭经，痛经，崩带淋浊，瘀滞胁痛，疝瘕积聚，跌扑损伤。用于温毒发斑，吐血衄血，目赤肿痛，肝郁胁痛，经闭痛经，症瘕腹痛，跌扑损伤，痈肿疮疡。
薏苡仁【来源】 本品为禾本科植物薏苡Coix lacryma-jobi L. var. ma-yuen （Roman.）Stapf的干燥成熟种仁。【性味】 甘、淡，凉。【归经】 归脾、胃、肺经。【功能主治】 健脾渗湿，除痹止泻，清热排浓。用于水肿，脚气，小便不利，湿痹拘挛，脾虚泄泻，肺痈，肠痈，扁平疣。
升麻【来源】 本品为毛茛科植物大三叶升麻Cimicifuga heracleifolia Kom. 、兴安升麻Cimicifuga dahurica （Turcz.）Maxim . 或升麻Cimicifuga foetida L. 的干燥根茎。【性味】 辛、微甘，微寒。【归经】 归肺、脾、胃、大肠经。【功能主治】 发表透疹，清热解毒，升举阳气。用于风热头痛，齿痛，口疮，咽喉肿痛，麻疹不透，阳毒发斑，脱肛，子宫脱垂。
当归【来源】 本品为伞形科植物当归Angelica sinensis （Oliv.） Diels 的干燥根。【性味】 甘、辛，温。【归经】 归肝、心、脾经。【功能主治】 补血活血，调经止痛，润肠通便。用于血虚萎黄，眩晕心悸，月经不调，经闭痛经，虚寒腹痛，肠燥便秘，风湿痹痛，跌扑损伤，痈疽疮疡。
紫草【来源】 本品为紫草科植物新疆紫草Arnebia euchroma （Royle）Johnst. 、紫草Lithospermum erythrorhizon Sieb. et Zucc. 或内蒙紫草Arnebia guttata Bunge 的干燥根。【性味】 甘、咸，寒。【归经】 归心、肝经。【功能主治】 凉血，活血，解毒透疹。用于血热毒盛，斑疹紫黑，麻疹不透，疮疡，湿疹，水火烫伤。
玄参【来源】 本品为玄参科植物玄参Scrophularia ningpoensis Hemsl.的干燥根。【性味】 甘、苦、咸，微寒。【归经】 归肺、胃、肾经。【功能主治】 凉血滋阴，泻火解毒。用于热病伤阴，舌绛烦渴，温毒发斑，津伤便秘，骨蒸劳嗽，目赤，咽痛，瘰疠，白喉，痈肿疮毒。
丹皮【来源】 本品为毛茛科植物牡丹Paeonia suffruticosa Andr.的干燥根皮。【性味】 苦、辛，微寒。【归经】 归心、肝、肾经。【功能主治】 清热凉血，活血化瘀。用于温毒发斑，吐血衄血，夜热早凉，无汗骨蒸，经闭痛经，痈肿疮毒，跌扑伤痛。
黄芩【来源】 本品为唇形科植物黄芩Scutellaria baicalensis Georgi的干燥根。【性味】 苦，寒。【归经】 归肺、胆、脾、大肠、小肠经。【功能主治】 清热燥湿，泻火解毒，止血，安胎。用于湿温、暑温胸闷呕恶，湿热痞满，泻痢，黄疸，肺热咳嗽，高热烦渴，血热吐衄，痈肿疮毒，胎动不安。
栀子【来源】 本品为茜草科植物栀子Gardenia jasminoides Ellis的干燥成熟果实。【性味】 苦，寒。【归经】 归心、肺、三焦经。【功能主治】泻火除烦，清热利尿，凉血解毒。用于热病心烦，黄疸尿赤，血淋涩痛，血热吐衄，目赤肿痛，火毒疮疡。
炒僵蚕【来源】 本品为蚕蛾科昆虫家蚕Bombyx mori Linnaeus. 4～5龄的幼虫感染（或人工接种）白僵菌Beauveria bassiana（Bals.）Vuillant而致死的幼虫干燥体。炒僵蚕：取净僵蚕，按照麸炒法炒至表面黄色。【性味】 咸、辛，平。【归经】 归肝、肺、胃经。【功能主治】 祛风定惊，化痰散结。用于惊风抽搐，咽喉肿痛，皮肤瘙痒，颌下淋巴结炎，面神经麻痹。
大黄【来源】 本品为蓼科植物掌叶大黄Rheum palmatum L、 唐古特大黄Rheum tanguticum Maxim。 ex Balf、或药用大黄Rheum officinale Baill。的干燥根及根茎。【性味】 苦，寒。【归经】 归脾、胃、大肠、肝、心包经。【功能主治】 泻热通肠，凉血解毒，逐瘀通经。用于实热便秘，积滞腹痛，泻痢不爽，湿热黄疸，血热吐衄，目赤，咽肿，肠痈腹痛，痈肿疔疮，瘀血经闭，跌打损伤，上消化道出血。
白芷【来源】 本品为伞型科植物白芷Angelica dahurica （Fisch.ex Hoffm.） Benth. et Hook.f.或杭白芷Angelica dahurica（Fisch.ex Hoffm.） Benth.et Hook.f. var.formosana（Boiss.）Shan et Yuan 的干燥根。【性味】 辛，温。【归经】 归胃、大肠、肺经。【功能主治】 散风除湿，通窍止痛，消肿排脓。用于感冒头痛，眉棱骨痛，鼻塞，鼻渊，牙痛，白带，疮疡肿痛。
蜈蚣【来源】 本品为蜈蚣科动物少棘巨蜈蚣Scolopendra subspinipes mutilans L. Koch的干燥体。【性味】 辛，温；有毒。【归经】 归肝经。【功能主治】 息风镇痉，功毒散结，通络止痛。用于小儿惊风，抽搐痉挛，中风口歪，半身不遂，破伤风，风湿顽痹，疮疡，瘰疬，毒蛇咬伤。
甘草【来源】 本品为豆科植物甘草 Glycyrrhiza uralensis Fisch.、胀果甘草 Glycyrrhiza inflata Bat. 或光果甘草 Glycyrrhiza glabra L. 的干燥根。【性味】 甘，平。【归经】 归心、肺、脾、胃经 。【功能主治】 补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
牡蛎【来源】 本品为牡蛎科动物长牡蛎Ostrea gigas Thunberg、大连湾牡蛎Ostrea talienwhanensis Crosse 或近江牡蛎Ostrea rivularis Gould的贝壳。【性味】 咸，微寒。【归经】 归肝、胆、肾经。【功能主治】 重镇安神，潜阳补阴，软坚散结。用于惊悸失眠，眩晕耳鸣，瘰疬痰核，症瘕痞块。
炒王不留【来源】 本品为石竹科植物麦蓝菜Vaccaria segetalis （Neck.）Garcke 的干燥成熟种子。【性味】 苦，平。【归经】 归肝、胃经。【功能主治】 活血通经，下乳消肿。用于乳汁不下，经闭，痛经，乳痈肿痛。
发明内容
本发明的目的旨在提供一种治疗瘀阻脉络症型瘰疬病的中药，通过选择合适的药材及其配比，达到安全有效治愈瘀阻脉络症型瘰疬病的目的。
为实现上述目的，本发明采用的技术方案是：
一种治疗瘀阻脉络症型瘰疬病的中药，其特征是由下列重量配比的药材制备而成：麻黄10份、连翘30份、赤芍15份、薏苡仁30份、升麻6份、当归10份、紫草10份、玄参12份、丹皮10份、黄芩10份、栀子10份、炒僵蚕10份、大黄10份、白芷10份、蜈蚣1条，甘草6份、牡蛎30份、炒王不留6份。
本发明将这些药材有机的组合在一起，各种药物相互配合，协合作用，所制得的中药具有化痰去瘀，软坚散结，活血通络，兼以清热解毒的功效，对治疗瘀阻脉络症型瘰疬病，具有十分显著的疗效。
下面给合临床实验数据说明本发明的有益效果：
1、 一般资料：
发明人2009年1月份2012年12月间共收集了56例确诊为瘀阻脉络症型瘰疬病的患者，年龄在29-46岁，病程2-13个月。随机分组为：治疗组为40例，空白组16例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法：
2.1治疗组口服本发明按照具体实施例1制得的胶囊，一日3次。疗程4个月。
2.2空白组口服瘰疬丸,一日3次。疗程4个月。
3、疗效标准与治疗效果：
3．1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3．2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率（%） |
| 治疗组 | 40 | 6 | 30 | 4 | 90% |
| 空白组 | 16 | 2 | 7 | 7 | 56.25% |
可见本发明的中药能够安全有效地治疗瘀阻脉络症型瘰疬病。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1：
称取麻黄10克、连翘30克、赤芍15克、薏苡仁30克、升麻6克、当归10克、紫草10克、玄参12克、丹皮10克、黄芩10克、栀子10克、炒僵蚕10克、大黄10克、白芷10克、蜈蚣1条，甘草6克、牡蛎30克、炒王不留6克，加8倍量水，煎煮1.5小时，过滤，滤渣加6倍量水，煎煮1小时，过滤，合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人3天用量的胶囊剂。
用于治疗瘀阻脉络症型瘰疬病，口服，每日早、中、晚三次服用。
具体实施例2：
称取麻黄10克、连翘30克、赤芍15克、薏苡仁30克、升麻6克、当归10克、紫草10克、玄参12克、丹皮10克、黄芩10克、栀子10克、炒僵蚕10克、大黄10克、白芷10克、蜈蚣1条，甘草6克、牡蛎30克、炒王不留6克，加10倍量水，煎煮2小时，过滤，滤渣加8倍量水，煎煮1.5小时，过滤，合并滤液，浓缩，干燥，包装，即得符合正常成人3天用量的散剂。
用于治疗瘀阻脉络症型瘰疬病，口服，每日早、中、晚三次服用。
具体实施例3：
称取麻黄10克、连翘30克、赤芍15克、薏苡仁30克、升麻6克、当归10克、紫草10克、玄参12克、丹皮10克、黄芩10克、栀子10克、炒僵蚕10克、大黄10克、白芷10克、蜈蚣1条，甘草6克、牡蛎30克、炒王不留6克，加8倍量水，煎煮1.5小时，过滤，滤渣加6倍量水，煎煮1.5小时，过滤，合并滤液，浓缩，干燥，再加入适量糊精与矫味剂,按照本领域常规工艺制粒,包装,即可制得符合正常成人3天用量的颗粒剂。
用于治疗瘀阻脉络症型瘰疬病，口服，每日早、中、晚三次服用。
Claims (1)
1.一种治疗瘀阻脉络症型瘰疬病的中药，其特征是由下列重量配比的药材制备而成：麻黄10份、连翘30份、赤芍15份、薏苡仁30份、升麻6份、当归10份、紫草10份、玄参12份、丹皮10份、黄芩10份、栀子10份、炒僵蚕10份、大黄10份、白芷10份、蜈蚣1条，甘草6份、牡蛎30份、炒王不留6份。
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| CN102247585A (zh) * | 2010-05-20 | 2011-11-23 | 潘治宇 | 治疗痹症的中药组合物其制剂及制备方法 |
| CN102335403A (zh) * | 2011-10-09 | 2012-02-01 | 许俊斋 | 一种治疗甲状腺癌、恶性淋巴结瘤的药物 |
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| CN102247585A (zh) * | 2010-05-20 | 2011-11-23 | 潘治宇 | 治疗痹症的中药组合物其制剂及制备方法 |
| CN102335403A (zh) * | 2011-10-09 | 2012-02-01 | 许俊斋 | 一种治疗甲状腺癌、恶性淋巴结瘤的药物 |
Non-Patent Citations (1)
| Title |
|---|
| 自拟瘰疬丸为主治疗淋巴结结核47例报告;李守静等;《河南中医》;19971231;第17卷(第4期);217-218页 * |
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