CN103536725A - 一种不换金正气散的制备方法及应用 - Google Patents
一种不换金正气散的制备方法及应用 Download PDFInfo
- Publication number
- CN103536725A CN103536725A CN201310529174.2A CN201310529174A CN103536725A CN 103536725 A CN103536725 A CN 103536725A CN 201310529174 A CN201310529174 A CN 201310529174A CN 103536725 A CN103536725 A CN 103536725A
- Authority
- CN
- China
- Prior art keywords
- processed
- priceless
- powder
- preparation
- health restoring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000843 powder Substances 0.000 title claims abstract description 45
- 238000002360 preparation method Methods 0.000 title claims abstract description 24
- 239000003814 drug Substances 0.000 claims abstract description 29
- 229940079593 drug Drugs 0.000 claims abstract description 19
- 238000000194 supercritical-fluid extraction Methods 0.000 claims abstract description 16
- 235000012907 honey Nutrition 0.000 claims abstract description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 238000000605 extraction Methods 0.000 claims description 12
- 230000004663 cell proliferation Effects 0.000 claims description 9
- 206010020880 Hypertrophy Diseases 0.000 claims description 8
- 206010028980 Neoplasm Diseases 0.000 claims description 8
- 201000011510 cancer Diseases 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 6
- 230000002401 inhibitory effect Effects 0.000 abstract description 3
- 201000009030 Carcinoma Diseases 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 241000699670 Mus sp. Species 0.000 abstract 1
- 240000007594 Oryza sativa Species 0.000 abstract 1
- 235000007164 Oryza sativa Nutrition 0.000 abstract 1
- 240000002505 Pogostemon cablin Species 0.000 abstract 1
- 235000011751 Pogostemon cablin Nutrition 0.000 abstract 1
- 244000273928 Zingiber officinale Species 0.000 abstract 1
- 235000006886 Zingiber officinale Nutrition 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 235000008397 ginger Nutrition 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 210000003630 histaminocyte Anatomy 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 235000009566 rice Nutrition 0.000 abstract 1
- 238000002474 experimental method Methods 0.000 description 8
- 229960004756 ethanol Drugs 0.000 description 5
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 4
- 239000006144 Dulbecco’s modified Eagle's medium Substances 0.000 description 3
- 230000010261 cell growth Effects 0.000 description 3
- 239000012531 culture fluid Substances 0.000 description 3
- 229960000935 dehydrated alcohol Drugs 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 239000006285 cell suspension Substances 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- WEEMDRWIKYCTQM-UHFFFAOYSA-N 2,6-dimethoxybenzenecarbothioamide Chemical compound COC1=CC=CC(OC)=C1C(N)=S WEEMDRWIKYCTQM-UHFFFAOYSA-N 0.000 description 1
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 206010003591 Ataxia Diseases 0.000 description 1
- 206010008531 Chills Diseases 0.000 description 1
- 206010008631 Cholera Diseases 0.000 description 1
- 206010010947 Coordination abnormal Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 238000002965 ELISA Methods 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 229920002334 Spandex Polymers 0.000 description 1
- 102000004142 Trypsin Human genes 0.000 description 1
- 108090000631 Trypsin Proteins 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000010165 autogamy Effects 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- FCPVYOBCFFNJFS-LQDWTQKMSA-M benzylpenicillin sodium Chemical compound [Na+].N([C@H]1[C@H]2SC([C@@H](N2C1=O)C([O-])=O)(C)C)C(=O)CC1=CC=CC=C1 FCPVYOBCFFNJFS-LQDWTQKMSA-M 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000010219 correlation analysis Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 239000012738 dissolution medium Substances 0.000 description 1
- 231100000673 dose–response relationship Toxicity 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 208000016290 incoordination Diseases 0.000 description 1
- 238000004900 laundering Methods 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 239000004759 spandex Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 229960002385 streptomycin sulfate Drugs 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
Abstract
Description
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310529174.2A CN103536725B (zh) | 2013-10-31 | 2013-10-31 | 一种不换金正气散的制备方法及应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310529174.2A CN103536725B (zh) | 2013-10-31 | 2013-10-31 | 一种不换金正气散的制备方法及应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103536725A true CN103536725A (zh) | 2014-01-29 |
CN103536725B CN103536725B (zh) | 2015-09-09 |
Family
ID=49960839
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310529174.2A Expired - Fee Related CN103536725B (zh) | 2013-10-31 | 2013-10-31 | 一种不换金正气散的制备方法及应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN103536725B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104922227A (zh) * | 2015-05-28 | 2015-09-23 | 吉林省正和药业集团股份有限公司 | 一种元和正胃片的制备方法及应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1718232A (zh) * | 2005-06-16 | 2006-01-11 | 广州中医药大学 | 一种治疗急性胃肠炎症和抗流感病毒的复方制剂及其制备方法 |
CN102988667A (zh) * | 2012-10-15 | 2013-03-27 | 李正梅 | 一种调经活血片的制备方法及应用 |
-
2013
- 2013-10-31 CN CN201310529174.2A patent/CN103536725B/zh not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1718232A (zh) * | 2005-06-16 | 2006-01-11 | 广州中医药大学 | 一种治疗急性胃肠炎症和抗流感病毒的复方制剂及其制备方法 |
CN102988667A (zh) * | 2012-10-15 | 2013-03-27 | 李正梅 | 一种调经活血片的制备方法及应用 |
Non-Patent Citations (1)
Title |
---|
中华人民共和国卫生部药典委员会: "《中华人民共和国卫生部药品标准中药成方制剂(第一册)》", 31 December 1989, article "不换金正气散" * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104922227A (zh) * | 2015-05-28 | 2015-09-23 | 吉林省正和药业集团股份有限公司 | 一种元和正胃片的制备方法及应用 |
Also Published As
Publication number | Publication date |
---|---|
CN103536725B (zh) | 2015-09-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103494848A (zh) | 一种沙棘黄酮的提取方法及应用 | |
CN103536739A (zh) | 一种左归丸的制备方法及应用 | |
CN103599292B (zh) | 一种归芍六君丸的制备方法及应用 | |
CN103494885B (zh) | 一种通窍鼻炎片的制备方法及应用 | |
CN103536725B (zh) | 一种不换金正气散的制备方法及应用 | |
CN103520446B (zh) | 一种正骨紫金丸的制备方法及应用 | |
CN103599493A (zh) | 一种利肝隆片的制备方法及应用 | |
CN103494864A (zh) | 一种绞股蓝总苷的提取方法及应用 | |
CN103550738B (zh) | 一种丹桅逍遥丸的制备方法及应用 | |
CN103494915B (zh) | 一种乳块消片的制备方法及应用 | |
CN103536691B (zh) | 一种五味子丸的制备方法及应用 | |
CN104922227A (zh) | 一种元和正胃片的制备方法及应用 | |
CN103720799A (zh) | 一种活络消痛片的制备方法及应用 | |
CN103550466A (zh) | 一种右归丸的制备方法及应用 | |
CN103656600A (zh) | 一种十二温经丸的制备方法及应用 | |
CN103721136B (zh) | 一种咽炎片的制备方法及应用 | |
CN103536654B (zh) | 一种川芎茶调丸的制备方法及应用 | |
CN103463581B (zh) | 一种利胆排石片的制备方法及应用 | |
CN103536733B (zh) | 一种十珍香附丸的制备方法及应用 | |
CN103721071B (zh) | 一种玉露保肺丸的制备方法及应用 | |
CN103638487B (zh) | 一种八宝瑞生丸的制备方法及应用 | |
CN103638489B (zh) | 一种补肾丸的制备方法及应用 | |
CN104906260A (zh) | 一种消风止痒颗粒的制备方法及应用 | |
CN104997966A (zh) | 一种辛芩颗粒的制备方法及应用 | |
CN103599217A (zh) | 一种咳喘丸的制备方法及应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: YIWU LVMEI BIOTECHNOLOGY CO., LTD. Free format text: FORMER OWNER: LIU MEIFU Effective date: 20150611 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20150611 Address after: The temple town of Yiwu city in Zhejiang province Jinhua city 322002 Leaf Village No. 81 Applicant after: YIWU LVMEI BIOTECHNOLOGY CO., LTD. Address before: The 5 group of Yiwu city residential streets in Zhejiang province Jinhua City mountain village 322008 Applicant before: Liu Meifu |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20151209 Address after: 223001 A-2 building, Huaian Science Park, 83 Beijing North Road, Huaian, Jiangsu Patentee after: JIANGSU HUIPU TECHNOLOGY CO., LTD. Address before: The temple town of Yiwu city in Zhejiang province Jinhua city 322002 Leaf Village No. 81 Patentee before: YIWU LVMEI BIOTECHNOLOGY CO., LTD. |
|
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150909 Termination date: 20161031 |