CN103536654B - 一种川芎茶调丸的制备方法及应用 - Google Patents
一种川芎茶调丸的制备方法及应用 Download PDFInfo
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- CN103536654B CN103536654B CN201310526906.2A CN201310526906A CN103536654B CN 103536654 B CN103536654 B CN 103536654B CN 201310526906 A CN201310526906 A CN 201310526906A CN 103536654 B CN103536654 B CN 103536654B
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- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- 239000003814 drug Substances 0.000 claims abstract description 18
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- 230000004663 cell proliferation Effects 0.000 claims abstract description 11
- 206010008342 Cervix carcinoma Diseases 0.000 claims abstract description 9
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- 201000010881 cervical cancer Diseases 0.000 claims abstract description 9
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 15
- 239000000843 powder Substances 0.000 claims description 13
- 238000000605 extraction Methods 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 238000001035 drying Methods 0.000 claims description 7
- 238000002156 mixing Methods 0.000 claims description 7
- 239000006187 pill Substances 0.000 claims description 7
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- 229960004756 ethanol Drugs 0.000 description 5
- 239000012467 final product Substances 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 4
- 239000006144 Dulbecco’s modified Eagle's medium Substances 0.000 description 3
- 230000010261 cell growth Effects 0.000 description 3
- 239000012531 culture fluid Substances 0.000 description 3
- 229960000935 dehydrated alcohol Drugs 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 239000006285 cell suspension Substances 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- WEEMDRWIKYCTQM-UHFFFAOYSA-N 2,6-dimethoxybenzenecarbothioamide Chemical compound COC1=CC=CC(OC)=C1C(N)=S WEEMDRWIKYCTQM-UHFFFAOYSA-N 0.000 description 1
- QZKDXSOKZHLFHE-UHFFFAOYSA-N 4-(1,3-benzodioxol-5-yl)benzoic acid Chemical compound C1=CC(C(=O)O)=CC=C1C1=CC=C(OCO2)C2=C1 QZKDXSOKZHLFHE-UHFFFAOYSA-N 0.000 description 1
- 206010063659 Aversion Diseases 0.000 description 1
- 238000002965 ELISA Methods 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010028748 Nasal obstruction Diseases 0.000 description 1
- 229920002334 Spandex Polymers 0.000 description 1
- 102000004142 Trypsin Human genes 0.000 description 1
- 108090000631 Trypsin Proteins 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000010165 autogamy Effects 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000010219 correlation analysis Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 239000012738 dissolution medium Substances 0.000 description 1
- 231100000673 dose–response relationship Toxicity 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000004900 laundering Methods 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
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- 238000000465 moulding Methods 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 239000004759 spandex Substances 0.000 description 1
- 229960002385 streptomycin sulfate Drugs 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
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Abstract
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201310526906.2A CN103536654B (zh) | 2013-10-30 | 2013-10-30 | 一种川芎茶调丸的制备方法及应用 |
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CN201310526906.2A CN103536654B (zh) | 2013-10-30 | 2013-10-30 | 一种川芎茶调丸的制备方法及应用 |
Publications (2)
Publication Number | Publication Date |
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CN103536654A CN103536654A (zh) | 2014-01-29 |
CN103536654B true CN103536654B (zh) | 2015-11-25 |
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CN201310526906.2A Expired - Fee Related CN103536654B (zh) | 2013-10-30 | 2013-10-30 | 一种川芎茶调丸的制备方法及应用 |
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CN (1) | CN103536654B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106492124A (zh) * | 2016-09-21 | 2017-03-15 | 深圳市得道中医馆管理有限责任公司 | 一种中药组合物及其制备方法和治疗宫颈癌的应用 |
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CN103536654A (zh) | 2014-01-29 |
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C41 | Transfer of patent application or patent right or utility model | ||
CB03 | Change of inventor or designer information |
Inventor after: Wu Yanghua Inventor before: Liu Meifu |
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TA01 | Transfer of patent application right |
Effective date of registration: 20151020 Address after: 311817 Zhuji City, Zhejiang province should shop Street Town Shop Street Village Town, Changxin Road, No. 8, No. Applicant after: Wu Yanghua Address before: The 5 group of Yiwu city residential streets in Zhejiang province Jinhua City mountain village 322008 Applicant before: Liu Meifu |
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C14 | Grant of patent or utility model | ||
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Address after: 5 A floor, 83 Huaian Science Park, Beijing North Road, Qinghe North Road, Qinghe District, Jiangsu, 223001 Patentee after: Wu Yanghua Address before: 311817 Zhuji City, Zhejiang province should shop Street Town Shop Street Village Town, Changxin Road, No. 8, No. Patentee before: Wu Yanghua |
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C41 | Transfer of patent application or patent right or utility model | ||
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Effective date of registration: 20160413 Address after: Chun Xi county of Nanjing City, Jiangsu province 211300 Gaochun Town Hing Road No. 95 Patentee after: Sun Aihua Address before: 5 A floor, 83 Huaian Science Park, Beijing North Road, Qinghe North Road, Qinghe District, Jiangsu, 223001 Patentee before: Wu Yanghua |
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C41 | Transfer of patent application or patent right or utility model | ||
CB03 | Change of inventor or designer information |
Inventor after: Zhao Nana Inventor after: Liu Fujun Inventor after: Sui Meixiang Inventor after: Yu Xiaohui Inventor before: Wu Yanghua |
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TR01 | Transfer of patent right |
Effective date of registration: 20160421 Address after: Dongguan village 266214 Shandong city of Laiyang province Chengxiang Street Office No. 50 Patentee after: Yu Xiaohui Address before: Chun Xi county of Nanjing City, Jiangsu province 211300 Gaochun Town Hing Road No. 95 Patentee before: Sun Aihua |
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CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151125 Termination date: 20161030 |