CN103534271B - 有免疫抑制活性的单克隆抗体或其抗原结合片段 - Google Patents
有免疫抑制活性的单克隆抗体或其抗原结合片段 Download PDFInfo
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- 230000014621 translational initiation Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 239000011534 wash buffer Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Biotechnology (AREA)
- Inorganic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010-185406 | 2010-08-20 | ||
| JP2010185406 | 2010-08-20 | ||
| PCT/JP2011/068793 WO2012023614A1 (ja) | 2010-08-20 | 2011-08-19 | 免疫抑制活性を有するモノクローナル抗体またはその抗原結合断片 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103534271A CN103534271A (zh) | 2014-01-22 |
| CN103534271B true CN103534271B (zh) | 2016-06-22 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180045987.3A Expired - Fee Related CN103534271B (zh) | 2010-08-20 | 2011-08-19 | 有免疫抑制活性的单克隆抗体或其抗原结合片段 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9701739B2 (enExample) |
| EP (1) | EP2631246B1 (enExample) |
| JP (1) | JP5960596B2 (enExample) |
| KR (1) | KR101863978B1 (enExample) |
| CN (1) | CN103534271B (enExample) |
| IN (1) | IN2013MN00513A (enExample) |
| RU (1) | RU2559550C2 (enExample) |
| TW (1) | TWI449710B (enExample) |
| WO (1) | WO2012023614A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103534271B (zh) | 2010-08-20 | 2016-06-22 | 学校法人城西大学 | 有免疫抑制活性的单克隆抗体或其抗原结合片段 |
| BR112014000630A2 (pt) | 2011-07-11 | 2017-02-14 | Glenmark Pharmaceuticals Sa | anticorpo antagonista ou fragmento do mesmo que se liga a uma ox40 humana, epítopo sobre o domínio extracelular ox40 humano, ácido nucleíco isolado, vetor, célula hospedeira, método para produzir um anticorpo ou fragmento do mesmo, composição imunoconjugado, método para tratar um distúrbio mediado por ox40 em um indivíduo, uso de um anticorpo ou fragmento do mesmo, artigo de manufatura, kit e método para classificação in vitro |
| JP2015117181A (ja) * | 2012-02-22 | 2015-06-25 | 学校法人 城西大学 | 敗血症治療剤 |
| WO2014127200A1 (en) * | 2013-02-15 | 2014-08-21 | Immunomedics, Inc. | Chimeric and humanized anti-histone antibodies |
| JPWO2013125687A1 (ja) * | 2013-02-22 | 2015-07-30 | 学校法人 城西大学 | 炎症疾患治療剤 |
| CN105850770A (zh) * | 2016-05-16 | 2016-08-17 | 贾文龙 | 一种宠物接便器 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101056979A (zh) * | 2004-09-03 | 2007-10-17 | 阿梅特拉斯法玛有限公司 | 抗组蛋白h1单克隆抗体及用于产生其的杂交瘤 |
| EP2196212A1 (en) * | 2007-10-04 | 2010-06-16 | Josai University Corporation | Preparation and method of administering vaccine and iontophoresis device using the preparation |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992011029A1 (en) * | 1990-12-17 | 1992-07-09 | The Johns Hopkins University | Suppression of immune responses with oligomeric forms of antigen of controlled chemistry |
| JP2004014950A (ja) | 2002-06-10 | 2004-01-15 | Nippon Tungsten Co Ltd | Ｐｔｃ特性を有するセラミックス材料 |
| JP2004149507A (ja) | 2002-09-05 | 2004-05-27 | Hisamitsu Pharmaceut Co Inc | 免疫抑制剤 |
| US20040052780A1 (en) | 2002-09-05 | 2004-03-18 | Hisamitsu Pharmaceutical Co., Inc. | Immunosuppresants |
| JPWO2009001673A1 (ja) | 2007-06-26 | 2010-08-26 | 学校法人 城西大学 | Ａｔｐ含有免疫アジュバント |
| WO2009004900A1 (ja) | 2007-06-29 | 2009-01-08 | Josai University Corporation | ユビキノン含有免疫アジュバント |
| US8716218B2 (en) | 2007-11-06 | 2014-05-06 | Oklahoma Medical Research Foundation | Extracellular histones as biomarkers for prognosis and molecular targets for therapy |
| CN103534271B (zh) | 2010-08-20 | 2016-06-22 | 学校法人城西大学 | 有免疫抑制活性的单克隆抗体或其抗原结合片段 |
| BR112014000630A2 (pt) | 2011-07-11 | 2017-02-14 | Glenmark Pharmaceuticals Sa | anticorpo antagonista ou fragmento do mesmo que se liga a uma ox40 humana, epítopo sobre o domínio extracelular ox40 humano, ácido nucleíco isolado, vetor, célula hospedeira, método para produzir um anticorpo ou fragmento do mesmo, composição imunoconjugado, método para tratar um distúrbio mediado por ox40 em um indivíduo, uso de um anticorpo ou fragmento do mesmo, artigo de manufatura, kit e método para classificação in vitro |
| JP2015117181A (ja) | 2012-02-22 | 2015-06-25 | 学校法人 城西大学 | 敗血症治療剤 |
-
2011
- 2011-08-19 CN CN201180045987.3A patent/CN103534271B/zh not_active Expired - Fee Related
- 2011-08-19 RU RU2013112324/10A patent/RU2559550C2/ru not_active IP Right Cessation
- 2011-08-19 IN IN513MUN2013 patent/IN2013MN00513A/en unknown
- 2011-08-19 KR KR1020137006995A patent/KR101863978B1/ko not_active Expired - Fee Related
- 2011-08-19 WO PCT/JP2011/068793 patent/WO2012023614A1/ja not_active Ceased
- 2011-08-19 JP JP2012529630A patent/JP5960596B2/ja active Active
- 2011-08-19 EP EP11818254.2A patent/EP2631246B1/en not_active Not-in-force
- 2011-08-19 TW TW100129738A patent/TWI449710B/zh not_active IP Right Cessation
- 2011-08-19 US US13/817,714 patent/US9701739B2/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101056979A (zh) * | 2004-09-03 | 2007-10-17 | 阿梅特拉斯法玛有限公司 | 抗组蛋白h1单克隆抗体及用于产生其的杂交瘤 |
| EP2196212A1 (en) * | 2007-10-04 | 2010-06-16 | Josai University Corporation | Preparation and method of administering vaccine and iontophoresis device using the preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103534271A (zh) | 2014-01-22 |
| RU2559550C2 (ru) | 2015-08-10 |
| EP2631246A4 (en) | 2014-01-15 |
| US20140010815A1 (en) | 2014-01-09 |
| WO2012023614A1 (ja) | 2012-02-23 |
| US9701739B2 (en) | 2017-07-11 |
| EP2631246A1 (en) | 2013-08-28 |
| TW201300416A (zh) | 2013-01-01 |
| JP5960596B2 (ja) | 2016-08-02 |
| JPWO2012023614A1 (ja) | 2013-12-12 |
| KR20130137612A (ko) | 2013-12-17 |
| IN2013MN00513A (enExample) | 2015-06-12 |
| KR101863978B1 (ko) | 2018-06-01 |
| RU2013112324A (ru) | 2014-09-27 |
| EP2631246B1 (en) | 2016-07-20 |
| TWI449710B (zh) | 2014-08-21 |
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