CN103506051A - Preparation method of plant surface active agent composition and application of the composition to washing supplies - Google Patents
Preparation method of plant surface active agent composition and application of the composition to washing supplies Download PDFInfo
- Publication number
- CN103506051A CN103506051A CN201310307540.XA CN201310307540A CN103506051A CN 103506051 A CN103506051 A CN 103506051A CN 201310307540 A CN201310307540 A CN 201310307540A CN 103506051 A CN103506051 A CN 103506051A
- Authority
- CN
- China
- Prior art keywords
- ethanol
- concentrated
- film
- preparation
- pressure reduction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention discloses a preparation method of a plant surface active agent composition. The invention mainly relates to a preparation process of a compound composition of a plurality of specific plant saponins, especially a preparation process as below: combined production of high purity plant saponins through efficient low temperature extraction, ultrasonic extraction, membrane separation and concentration, column chromatography purification and crystallization refining; and compound of the saponins according to a certain proportion to obtain the plant surface active agent composition. The plant surface active agent prepared by the invention can reduce stimulation of a traditional plant surface active agent, and can increase the surface tension and foaming performance.
Description
Technical field
The present invention relates to a kind of composite plant surface surfactant composition, said composition has emulsification, disperses, and clean, anti-bacterial, anti-itching effect, can be applied to shampoo, shower cream and clean product.
Background technology
Along with the raising of people's living standard and the enhancing of environmental protection consciousness, particularly in " cosmetics, bathing lotion ", there is in recent years the Harmful Residue event of hurting sb.'s feelings, make the whole society more pay close attention to the security of product to human body and environment.Because surfactant is that the form of filling a prescription adds in product and with human body and directly or indirectly contacts, finally enter nature; So develop nontoxic as far as possible and the free of contamination surfactant of ecological environment become to the focus that industry is paid close attention to.Plant surface activating agent be take natural plants as raw material, and process is pollution-free, and final products are nontoxic to human body, excitant is little and be easy to biodegradation.Beginning is applied in increasing articles for washing.But present stage, plant surface activating agent existed frothing capacity poor, formula is difficult for stable, and color is dark, and smell is the characteristic such as heavily, seriously restricted range of application.
Summary of the invention
The object of the invention is in order to overcome the defect of traditional plant surfactant, a kind of composite plant surface surfactant composition is provided.This plant surface surfactant composition has good surface-active, soil release performance, solubilising, foaming characteristic and foam stability; Acid and alkali-resistance, anti-hard water, compatibility are good; Nontoxic, excitant is little, easily biological-degradable.
For reaching the object of the invention, adopted following technical scheme:
A surfactant composition, is characterized in that the component that comprises following percentage by weight:
Concrete extraction and purification process is as follows:
1. the preparation method of sapindoside is: by soapberry pulverizing medicinal materials, sieve, medicinal material coarse powder is put in continous way height pressure reduction extractor, take 20-80% ethanol as solvent, height pressure reduction extracts, and filters, and film is concentrated, go up again large pore resin absorption column, be washed to colourless after, then use 20-80% ethanol elution colourless to eluent, and collect respectively ethanol eluate, the concentrated ethanol of removing of film, spraying is dried to obtain sapindoside powder.
2. the preparation method of Tea Saponin is: tea seed cake is pulverized, sieved, medicinal material coarse powder is put in continous way height pressure reduction extractor, take 20-80% ethanol as solvent, height pressure reduction extracts, and filters, and film is concentrated, go up again large pore resin absorption column, be washed to colourless after, then use 20-80% ethanol elution colourless to eluent, and collect respectively ethanol eluate, the concentrated ethanol of removing of film, spraying is dried to obtain Tea Saponin powder.
3. the preparation method of notoginsenoside is: pseudo-ginseng is pulverized, sieved, medicinal material coarse powder is put in continous way height pressure reduction extractor, take 20-80% ethanol as solvent, height pressure reduction extracts, and filters, and film is concentrated, go up again large pore resin absorption column, be washed to colourless after, then use 20-80% ethanol elution colourless to eluent, and collect respectively ethanol eluate, the concentrated ethanol of removing of film, spraying is dried to obtain notoginsenoside powder.
4. the preparation method of ginsenoside is: ginseng crude drug is pulverized, sieve, medicinal material coarse powder is put in continous way height pressure reduction extractor, take 20-80% ethanol as solvent, height pressure reduction extracts, and filters, and film is concentrated, go up again large pore resin absorption column, be washed to colourless after, then use 20-80% ethanol elution colourless to eluent, and collect respectively ethanol eluate, the concentrated ethanol of removing of film, spraying is dried to obtain ginsenoside powder.
5. the preparation method of Gleditschiasaponin is: by Chinese honey locust pulverizing medicinal materials, sieve, mix, take water as solvent, ultrasonic extraction, filters, and film is concentrated, and spraying is dry, and 95% ethanol dissolves, and filters, and reclaims ethanol, and Gleditschiasaponin is repeatedly recrystallized to obtain.
For fear of dissolvent residual, the extraction solvent using in the present invention is water, ethanol water.In order to obtain optimum extraction purification effect, the present invention has carried out extraction solvent, liquid material mass ratio, extraction time, and the screening of the extraction and purification process conditions such as pressure reduction/supersonic frequency has obtained optimum extraction purifying process condition, is shown in Table 1.
Table 1
| Natural materials | Extract solvent | Liquid material mass ratio | Extraction time | Pressure reduction/supersonic frequency | Macroreticular resin model | Wash-out concentration |
| Soapberry | 70% ethanol | 20∶1 | 30min | 0.5-10MPa | AB-8 | 70% ethanol |
| Tea seed cake | 70% ethanol | 20∶1 | 30min | 0.5-10MPa | HPD-100 | 80% ethanol |
| Pseudo-ginseng | 70% ethanol | 15∶1 | 25min | 0.5-10MPa | D101 | 70% ethanol |
| Ginseng | 70% ethanol | 15∶1 | 35min | 0.5-10MPa | D101 | 70% ethanol |
| Chinese honey locust | Water | 20∶1 | 30min | 1000kHz | ------ | ------ |
Above-mentioned plant surface surfactant composition washes in preparation the application of protecting in cosmetics, it is characterized in that containing above-mentioned plant surface surfactant composition in cosmetics, and its consumption is 5-45%, and preferable amount is 10-30%.Except containing above-mentioned plant surface surfactant composition, can suitably add as required and be applicable to the common composition that cosmetics are used, as matrix components such as NMF, softener, water.
Plant surface activating agent is washed the formulation of protecting cosmetics and is not particularly limited, and can be solution, emulsion, paste etc.
The present invention has the following advantages:
1. efficient cryogenic extracts, and has effectively suppressed the color in preparation process and has gradually deeply changed, and has reduced the decolouring step of separation and purification process, can not be limited in the addition in formula because of self color.The active matter sex change of simultaneously having avoided traditional extraction technique high temperature to cause, the problem such as unstable.
2. this plant surface surfactant composition be take natural plants as raw material, and preparation technology does not relate to poisonous and hazardous chemical reagent, does not have the risk of introducing dioxanes, and final product is gentle, stimulates little and easily biological-degradable.
The specific embodiment
By specific embodiment, come below that the present invention is further illustrated, but these embodiment are just in order to illustrate, are not limitations of the present invention.
Embodiment 1 surfactant evaluation experimental method and result
1. surfactant surface tension test
Adopt suspension ring method, measure the surface tension (γ) of the sample aqueous solution of variable concentrations (c) at 20 ℃, draw the relation curve of γ-lgc, the corresponding concentration in flex point place is cmc, and corresponding surface tension is γ
cmc.。
2. foam height
Utilize succusion, the foaming characteristic of working sample solution.Joined mixed aqueous solution 10mL is placed in to tool plug graduated cylinder (graduated cylinder high scale extend to demarcate to 140mL Chu， bottom scale extend to 5mL place).With forced oscillation solution 30 times of 2 times/s speed, record foam maximum height H.
3. fungistatic effect research
By above-mentioned plant surface surfactant composition, with 50% butanediol, dissolve, be mixed with 5% concentration, number A, carried out bacterium that hair (skin) easily grows and the bacteriostatic test of fungi, test as follows:
(1) test specimen
Totally 2 groups, number as follows
A plant surface surfactant composition solution
B 50% butanediol
(2) test index
Inhibition zone diameter (mm)
4. experimental result
The cmc of table 2 surfactant and γ
cmcnumerical value (testing oneself)
| Surfactant | cmc/mg＊L -1 | γ cmc/mN＊m -1 |
| Plant surface surfactant composition | 34.4 | 36.8 |
| AES ammonium salt | 85.1 | 30.5 |
| K 12Ammonium salt | 108.1 | 21.9 |
| AOS | 311.5 | 34.2 |
The frothing capacity of the plant surface surfactant composition solution of table 3 different quality concentration
The frothing capacity of table 4 different surfaces activating agent
| Surfactant | c/g＊L -1 | Foam height H/mm |
| Plant surface surfactant composition | 2.5 | 190 |
| AES ammonium salt | 2.5 | 210 |
| K 12Ammonium salt | 2.5 | 220 |
| AOS | 2.5 | 195 |
Plant surface surfactant composition has low cmc and γ
cmc, illustrating that its surface-active is strong, it can produce foam during very low concentrations in deionized water, and during to finite concentration, foam height reaches 195mm, and foam stabilization and persistence are good.Substantially can reach AES ammonium salt, K
12ammonium salt, the frothing capacity of AOS.
Table 5 broad spectrum activity bacteriostatic test result
Known according to experimental result, A is comparatively responsive to strain subject, and plant surface surfactant composition can reach good fungistatic effect.
Embodiment 2 plant surface surfactant compositions
Plant surface surfactant composition (I) is composed as follows by weight percentage:
Plant surface surfactant composition (II) is composed as follows by weight percentage:
Plant surface surfactant composition (III) is composed as follows by weight percentage:
3 clean mousses of embodiment
Clean mousse formula table of table 6
Technique:
1, A is added to dissolve complete mutually successively;
2, after being uniformly dissolved mutually in advance, B adds A phase;
3, add C to stir mutually.
Embodiment 4 scalp nursing solutions
Table 7 scalp nursing solution formula table
| Material title | Percentage consumption |
| Water | 86.40％ |
| Plant surface surfactant composition | 10.00％ |
| Glycerine | 3.00％ |
| Water-soluble silicon oil | 0.50％ |
| Kathon CG | 0.10％ |
Technique:
1, plant surface surfactant composition being added to the water to stirring is uniformly dissolved it.
2, glycerine is added and stirred.
3, water-soluble silicon oil is added and stirred.
4, Kathon CG is added and is stirred.
Embodiment 5 scalp nursing solution Hair setting performance test experiments
The scalp nursing solution of embodiment 4 preparations is done respectively the wet comb test of comb, tests its carding property.Its test procedure is as follows:
1. the pretreatment of blank topknot: the AES solution with 10% soaks and after ultrasonic 25 minutes, rinses well, extracts numbering.
2. the cardability of blank topknot test: start MTT175, open combing test program, it is 8mm/s that combing speed is set, tests the wet comb property of blank topknot respectively, is averaged carding force.After topknot is dry, do cardability test, method is with wet cardability test again, and record data are averaged carding force.
3. scalp nursing solution sample comb rationality test: above topknot with the blank scalp nursing solution of 3g and scalp nursing solution of the present invention washing, is complied with method and carried out cardability test respectively under wet and dry state, and record data, average respectively.
4. result of the test: cardability test result is as table 7:
Table 7 cardability test result
As can be seen from the above results, the scalp nursing solution containing plant surface surfactant composition of the present invention, can effectively improve Hair setting, and impaired hair quality is had to obvious reparation and protection effect.
Claims (2)
1. a plant surface surfactant composition, is characterized in that, by weight percentage, composed of the following components:
The preparation method of above-mentioned sapindoside is: by soapberry pulverizing medicinal materials, sieve, medicinal material coarse powder is put in continous way height pressure reduction extractor, take 20-80% ethanol as solvent, height pressure reduction extracts, and filters, and film is concentrated, go up again large pore resin absorption column, be washed to colourless after, then use 20-80% ethanol elution colourless to eluent, and collect respectively ethanol eluate, the concentrated ethanol of removing of film, spraying is dried to obtain sapindoside powder.
The preparation method of above-mentioned Tea Saponin is: tea seed cake is pulverized, sieved, medicinal material coarse powder is put in continous way height pressure reduction extractor, take 20-80% ethanol as solvent, height pressure reduction extracts, and filters, and film is concentrated, go up again large pore resin absorption column, be washed to colourless after, then use 20-80% ethanol elution colourless to eluent, and collect respectively ethanol eluate, the concentrated ethanol of removing of film, spraying is dried to obtain Tea Saponin powder.
The preparation method of above-mentioned notoginsenoside is: pseudo-ginseng is pulverized, sieve, medicinal material coarse powder is put in continous way height pressure reduction extractor, take 20-80% ethanol as solvent, height pressure reduction extracts, and filters, and film is concentrated, go up again large pore resin absorption column, be washed to colourless after, then use 20-80% ethanol elution colourless to eluent, and collect respectively ethanol eluate, the concentrated ethanol of removing of film, spraying is dried to obtain notoginsenoside powder.
The preparation method of above-mentioned ginsenoside is: ginseng is pulverized, sieved, medicinal material coarse powder is put in continous way height pressure reduction extractor, take 20-80% ethanol as solvent, height pressure reduction extracts, and filters, and film is concentrated, go up again large pore resin absorption column, be washed to colourless after, then use 20-80% ethanol elution colourless to eluent, and collect respectively ethanol eluate, the concentrated ethanol of removing of film, spraying is dried to obtain ginsenoside powder.
The preparation method of above-mentioned Gleditschiasaponin is: by Chinese honey locust pulverizing medicinal materials, sieve, mix, take water as solvent, ultrasonic extraction, filters, and film is concentrated, and spraying is dry, and 95% ethanol dissolves, and filters, and reclaims ethanol, and Gleditschiasaponin is repeatedly recrystallized to obtain.
2. plant surface surfactant composition claimed in claim 1 is washed the application of protecting on cosmetics in preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310307540.XA CN103506051A (en) | 2013-07-22 | 2013-07-22 | Preparation method of plant surface active agent composition and application of the composition to washing supplies |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310307540.XA CN103506051A (en) | 2013-07-22 | 2013-07-22 | Preparation method of plant surface active agent composition and application of the composition to washing supplies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103506051A true CN103506051A (en) | 2014-01-15 |
Family
ID=49889790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310307540.XA Pending CN103506051A (en) | 2013-07-22 | 2013-07-22 | Preparation method of plant surface active agent composition and application of the composition to washing supplies |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103506051A (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104644542A (en) * | 2015-03-13 | 2015-05-27 | 福建春辉生物工程有限公司 | Natural shower gel containing camellia saponin |
| CN104762144A (en) * | 2015-03-06 | 2015-07-08 | 天峨县平昌生态农业有限公司 | A plant liquid detergent |
| CN104873440A (en) * | 2015-06-11 | 2015-09-02 | 福建春辉生物工程有限公司 | Facial cleanser containing plant saponin and preparation method thereof |
| CN105055241A (en) * | 2015-08-17 | 2015-11-18 | 贵州华波日化有限公司 | Shower gel and preparation method thereof |
| CN105560123A (en) * | 2016-01-22 | 2016-05-11 | 柳州博泽科技有限公司 | Pure natural moisturizing facial cleanser |
| CN105596245A (en) * | 2015-07-09 | 2016-05-25 | 金品富 | Cake for washing hair, cleaning face and bathing as well as production method |
| CN107496287A (en) * | 2017-08-29 | 2017-12-22 | 广东芭薇生物科技股份有限公司 | The no added synthetic surfactant face cleaning product of whole plant |
| CN108245454A (en) * | 2018-02-26 | 2018-07-06 | 广州丽丰化妆品制造有限公司 | A kind of rich results hydrating cleanser containing natural anti-oxidation ingredient and preparation method thereof |
| CN108478494A (en) * | 2018-06-08 | 2018-09-04 | 中华全国供销合作总社南京野生植物综合利用研究所 | A kind of all natural shampoo |
| CN108524350A (en) * | 2018-03-30 | 2018-09-14 | 北京明弘科贸有限责任公司 | A kind of mild moisturizing cleansing water, preparation method and application without surfactant |
| CN109674707A (en) * | 2019-02-20 | 2019-04-26 | 张家界茶坤缘杜仲生物科技开发有限公司 | Cortex Eucommiae baby bath powder and preparation method thereof |
| CN112057379A (en) * | 2020-08-26 | 2020-12-11 | 广州德谷个人护理用品有限公司 | Scalp care composition capable of improving scalp microecological diversity and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1869055A (en) * | 2006-06-21 | 2006-11-29 | 海南亚洲制药有限公司 | Method of extracting and separating ginseng saponine monomer from ginseng leaf |
| CN102397183A (en) * | 2011-08-24 | 2012-04-04 | 珲春华瑞参业生物工程有限公司 | Ginseng and soapberry fermentation extract and its application in cosmetics |
| JP2013063932A (en) * | 2011-09-19 | 2013-04-11 | Yoshiro Nagado | Solid toothpaste using soapberry and coral powder and method of manufacturing the same |
| CN103215143A (en) * | 2013-03-15 | 2013-07-24 | 金红叶纸业集团有限公司 | Cleaning composition and facial tissue using the same |
| CN103251541A (en) * | 2013-05-30 | 2013-08-21 | 云南七丹药业股份有限公司 | Liquid shampoo containing notoginsenoside and preparation method thereof |
-
2013
- 2013-07-22 CN CN201310307540.XA patent/CN103506051A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1869055A (en) * | 2006-06-21 | 2006-11-29 | 海南亚洲制药有限公司 | Method of extracting and separating ginseng saponine monomer from ginseng leaf |
| CN102397183A (en) * | 2011-08-24 | 2012-04-04 | 珲春华瑞参业生物工程有限公司 | Ginseng and soapberry fermentation extract and its application in cosmetics |
| JP2013063932A (en) * | 2011-09-19 | 2013-04-11 | Yoshiro Nagado | Solid toothpaste using soapberry and coral powder and method of manufacturing the same |
| CN103215143A (en) * | 2013-03-15 | 2013-07-24 | 金红叶纸业集团有限公司 | Cleaning composition and facial tissue using the same |
| CN103251541A (en) * | 2013-05-30 | 2013-08-21 | 云南七丹药业股份有限公司 | Liquid shampoo containing notoginsenoside and preparation method thereof |
Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104762144A (en) * | 2015-03-06 | 2015-07-08 | 天峨县平昌生态农业有限公司 | A plant liquid detergent |
| CN104644542B (en) * | 2015-03-13 | 2018-01-05 | 福建春辉生物工程有限公司 | A kind of Value of natural bath ＆ shower dew containing Sasanguasaponin |
| CN104644542A (en) * | 2015-03-13 | 2015-05-27 | 福建春辉生物工程有限公司 | Natural shower gel containing camellia saponin |
| CN104873440A (en) * | 2015-06-11 | 2015-09-02 | 福建春辉生物工程有限公司 | Facial cleanser containing plant saponin and preparation method thereof |
| CN105596245A (en) * | 2015-07-09 | 2016-05-25 | 金品富 | Cake for washing hair, cleaning face and bathing as well as production method |
| CN105055241A (en) * | 2015-08-17 | 2015-11-18 | 贵州华波日化有限公司 | Shower gel and preparation method thereof |
| CN105055241B (en) * | 2015-08-17 | 2018-07-06 | 贵州伊美净日化有限公司 | A kind of shower cream preparation method and shower cream prepared therefrom |
| CN105560123A (en) * | 2016-01-22 | 2016-05-11 | 柳州博泽科技有限公司 | Pure natural moisturizing facial cleanser |
| CN107496287B (en) * | 2017-08-29 | 2021-03-16 | 广东芭薇生物科技股份有限公司 | Whole plant synthetic surfactant-free cleansing product |
| CN107496287A (en) * | 2017-08-29 | 2017-12-22 | 广东芭薇生物科技股份有限公司 | The no added synthetic surfactant face cleaning product of whole plant |
| CN108245454A (en) * | 2018-02-26 | 2018-07-06 | 广州丽丰化妆品制造有限公司 | A kind of rich results hydrating cleanser containing natural anti-oxidation ingredient and preparation method thereof |
| CN108245454B (en) * | 2018-02-26 | 2020-12-04 | 广州丽丰化妆品制造有限公司 | Mild cleansing cream containing natural antioxidant components and preparation method thereof |
| CN108524350A (en) * | 2018-03-30 | 2018-09-14 | 北京明弘科贸有限责任公司 | A kind of mild moisturizing cleansing water, preparation method and application without surfactant |
| CN108478494A (en) * | 2018-06-08 | 2018-09-04 | 中华全国供销合作总社南京野生植物综合利用研究所 | A kind of all natural shampoo |
| CN109674707A (en) * | 2019-02-20 | 2019-04-26 | 张家界茶坤缘杜仲生物科技开发有限公司 | Cortex Eucommiae baby bath powder and preparation method thereof |
| CN112057379A (en) * | 2020-08-26 | 2020-12-11 | 广州德谷个人护理用品有限公司 | Scalp care composition capable of improving scalp microecological diversity and preparation method thereof |
| CN112057379B (en) * | 2020-08-26 | 2021-08-06 | 广州德谷个人护理用品有限公司 | Scalp care composition capable of improving scalp microecological diversity and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103506051A (en) | Preparation method of plant surface active agent composition and application of the composition to washing supplies | |
| CN103494754B (en) | Hair-loss preventing and hair-restoring shampoo of herbal essences and biochemical component formula and preparation method thereof | |
| CN105997735B (en) | A kind of natural hair-washing hair-care articles and its preparation method and application | |
| CN106010831B (en) | A kind of handmade soap and preparation method thereof | |
| CN104921998A (en) | Process for simultaneously extracting pigments, saponins and polysaccharides of sapindus, and preparation and application of saponins of sapindus | |
| WO2018045579A1 (en) | All-natural shampoo | |
| CN101838292B (en) | Method for extracting and separating polyphenol from plants | |
| CN107898686B (en) | Agar extract, preparation method and application thereof in cosmetics | |
| US20120142570A1 (en) | Herbal cleansing composition and method of preparing the same | |
| KR20230052700A (en) | Anti-pollution cosmetic composition containing camellia extract, aurea helianthus extract, carpinus tschonoskii extract, silkworm extract and centella asiatica extract | |
| CN106937926B (en) | A kind of preparation method of the natural shampoo of anti-dandruff and itching-relieving maintenance unification | |
| CN103446563B (en) | Suppress Anti-hair loss Chinese herb compound of 5α-reductase activity and preparation method thereof | |
| CN112754969A (en) | Shower gel formula | |
| CN116240259A (en) | Method for extracting compound from ginseng, ginseng extract containing the compound, and composition for enhancing skin barrier containing the same | |
| KR101437336B1 (en) | Natural cleansing composition for improving hair and scalp comprising fermented needle-leaf extracts | |
| CN107760493A (en) | It is a kind of to contribute to anti-oxidant, anti-aging soap of Chinese medicine preparation method | |
| CN112515995A (en) | Shampoo bath lotion containing tea seed oil and preparation method thereof | |
| CN103405364B (en) | Traditional Chinese medicine composition with whitening effect, and preparation method and application thereof | |
| CN106635529A (en) | Geranium essential oil handmade soap and preparation method thereof | |
| CN113893196A (en) | A bath product containing natural plant extract | |
| CN104027378A (en) | Skin external composition comprising lonicera japonica vinegar extract | |
| CN112852549A (en) | Method for extracting plant hydrolat by using double auxiliary agents | |
| JP4223170B2 (en) | Hair composition | |
| CN106083984A (en) | A kind of method from extracting tea saponin from tea seed meal | |
| CN110638677A (en) | Volcanic mud makeup removing lotion and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140115 |