CN103495001A - Traditional Chinese medicine composition for treating dizziness, stroke and dementia disease - Google Patents
Traditional Chinese medicine composition for treating dizziness, stroke and dementia disease Download PDFInfo
- Publication number
- CN103495001A CN103495001A CN201310453940.1A CN201310453940A CN103495001A CN 103495001 A CN103495001 A CN 103495001A CN 201310453940 A CN201310453940 A CN 201310453940A CN 103495001 A CN103495001 A CN 103495001A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- chinese medicine
- medicine composition
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention provides a traditional Chinese medicine composition for treating dizziness, stroke and dementia disease. The composition comprises the following raw materials in parts by weight: 2-6 parts of musk, 10-50 parts of salvia miltiorrhiza, 12-60 parts of dragon's blood, 7-35 parts of prepared rehmannia root, 3-15 parts of deer-horn glue, 3-15 parts of prepared monkshood, 3-15 parts of codonopsis pilosula, 3-15 parts of liquorice, 3-15 parts of poria with hostwood, 3-15 parts of spina date seed and 3-15 parts of medicated leaven. The medicinal raw materials are combined to generate a synergistic effect, so that the effects of refreshing mind, inducing resuscitation, promoting blood circulation to remove blood stasis, tonifying spleen to remove dampness, nourishing kidneys and tonifying qi can be effectively achieved, and the aims of treating and preventing dizziness, stroke, dementia disease, cerebral infarction and cerebral thrombosis are fulfilled.
Description
Technical field
The present invention relates to belong to the field of Chinese medicines, particularly relate to a kind of Chinese medicine composition for the treatment of dizzy, apoplexy, dementia and preparation method thereof.
Background technology
Along with social development, people's living standard improves constantly, Modern Live rhythm is accelerated day by day, from work, family, the pressure of all sectors of society increases severely day by day, make many people's psychology, a series of abnormal phenomena has appearred in physiology, as dizzy, apoplexy, the generation of the diseases such as dementia, have a strong impact on work, study, life, and even threat to life, these diseases are common clinicals, add up according to investigations, this class disease has the gesture of increase year by year, carrying out this class disease prevention and treating is we clinician's responsibility, simultaneously, it is effective that extensive patients also urgently wishes that the medical personnel constantly works out, the new results of instant effect, be the extensive patients service better.
Vertiginous disorder, the cause of disease is many by seven emotions, injury due to diet, and overstrain, lose blood due to.Its disease position is at clear key, and, mistake hollow by brains supported to reach on phlegm-fire and turned over and cause, relevant with conscience spleen kidney four dirty functional disorders.
Apoplexy, easy acute outbreak belongs to critical severe disease, should rescue in time processing, clinical very common.Its cause of disease be take and amassed damage and just declining as main, and sick position, at brain, often relates to conscience spleen kidney four dirty, and its pathogenesis is how disorderly contrary by QI and blood, causes brain arteries and veins impatency, or outside blood oozing from the body openings or subcuta neous tissue brain feeling pulse.The clinical brains god machine extent of damage difference of pressing, can be divided into apoplex involving the channels and collaterals and the large type of Hitting Viscera two.
Dementia, belong to common clinical.Its cause of disease is hindered with feelings will, and body deficiency due to old age is main, and sick position is at brain, closely related with conscience spleen kidney four dirty functional disorders, and its pathogenesis is, marrow subtracts brain and disappears, refreshing machine apraxia, and characteristic of disease be take void as this, take reality as mark, clinical often with simulataneous insufficiency and excessive.
Situation in sum, we can find out that dizzy, apoplexy, dull-witted these three kinds of diseases have its common feature, from sick position, sick position all at brain, at clear key; From characteristic of disease, the three all be take void as this, and simulataneous insufficiency and excessive is often arranged; From the cause of disease, 1. damaged by excess of seven emotions, feelings will is too drastic, incoordination of seven emotions, the liver losing its smoothly moving state, depression and stagnation of QI, courage and uprightness are not smooth, pent-up brain arteries and veins; The rage impairing the liver, liver-yang is quick-fried high, or the quick-fried Sheng of heart-fire, fire and wind stirring up each other, bleeding resulting from adverse flow of QI, upper punch is turned over brain.2. long-pending damage just declines, old or prolonged illness deficiency of both QI and blood, and first QI consumed wound, the brain arteries and veins loses supports.It is unable that the deficiency of vital energy is transported blood, thrombosis, and the brain arteries and veins stasis of blood that arrives is stagnant obstructed; Deficiency of YIN-blood is the moon Zhiyang not, and interior pneumatic jumping taken that expectorant is turbid, disturbed clearly key on congestion and send out primary disease.3. overstrain internal injury, " yang-energy person, all labor is clear ".All labor is excessive, easily makes yang-energy growth, priming wind sun, and endogenous wind turn gas fire tool floatingly or double is taken that expectorant is turbid, is gushed key venation clearly on congestion, and the generation of this disease that arrives.4. with conscience spleen kidney four dirty functional disorders, substantial connection is arranged, heart governing blood and vessels mind, blood stored in the liver, spleen hemopoietic system blood is the foundation of acquired constitution, kidney storing essence is the congenital foundation, four dirty orthofunctions, the guarantee brain is clear-headed, resourceful, is unlikely to occur above-mentioned disease.
Make a general survey of three diseases, due to patient's visceral dysfunction, " Nian Sishi and because of it from half, decline of vitality in daily life with ".Old, QI and blood deficiency, deficiency of kidney-essence, brain arteries and veins inanition, overstrain internal injury, the cause of disease such as seven emotions and arriving.The pathogenic factor such as gas, blood, expectorant, strongly fragrant, the stasis of blood are for suffering from, and cause brain arteries and veins impatency and have a dizzy spell, the headache feeling of fullness in the head; QI and blood is contrary disorderly, outside blood oozing from the body openings or subcuta neous tissue brain feeling pulse, causes and flutters dusk unsuccessfully, sends out as apoplexy; The kidney essense loss, brains lose to support and disappear for marrow subtracts brain, and refreshing machine apraxia forms dementia.
Although it is very thorough that doctor trained in Western medicine is familiar with on pathology dizzy, apoplexy, dementia, in treatment, except the apoplexy acute attack stage, need doctor trained in Western medicine rescue in time, one when entering convalescent treatment, also roughly the same with dizzy, dull-witted Therapeutic Method, improve the medicines such as cerebral circulation and nutrition cranial nerve nothing more than employing and carry out anti symptom treatment, therefore much treatment also needs a process, and Timing is long again, patient's obstinates and often seeking medical advice in traditional medicine synthetic therapy.
Chinese medicine is dizzy in prophylactic treatment, have comparatively significant curative effect and advantage aspect apoplexy, dementia.Especially Chinese patent medicine market kind is more, as the injection ligustrazine of Chinese medicine extraction, ginkgo bilobate extract, Radix Salviae Miltiorrhizae, ginseng rhizome of chuanxiong glucose injection etc.; Also have oral DANQI PIAN, Rhizoma Gastrodiae granule, prick the medicines such as punching ten triplex pills, NAOXINTONG, Radix Salviae Miltiorrhizae Tabellae, be prevention and treat dizzy, apoplexy, dementia has played positive effect.In order to carry forward motherland's medicine culture, weed out the old and bring forth the new, working out new drug a kind of with strong points, evident in efficacy is better the extensive patients service, is we traditional Chinese medical science scholar's responsibility.
Summary of the invention
The purpose of this invention aims to provide a kind of consciousness-restoring and orifice-opening that has, blood circulation promoting and blood stasis dispelling, and spleen invigoratingization is turbid, and the effect of tonifying Qi of the kidney also can be prevented the Chinese medicine composition of cerebral infarction, cerebral thrombosis.
Another purpose of this invention has aimed to provide the preparation method of this Chinese medicine composition.
This invention technical scheme be:
A kind of Chinese medicine composition that is used for the treatment of dizzy, apoplexy, dementia, the composition by weight compatibility of composition material is: Moschus 2-6 part, Radix Salviae Miltiorrhizae 10-50 part, Sanguis Draxonis 12-60 part, Radix Rehmanniae Preparata 7-35 part, Colla cornus cervi 3-15 part, Radix Aconiti Lateralis Preparata 3-15 part, Radix Codonopsis 3-15 part, Radix Glycyrrhizae 3-15 part, Poria cum Radix Pini 3-15 part, Semen Ziziphi Spinosae 3-15 part, Massa Medicata Fermentata 3-15 part.
The part by weight compatibility of this invention Chinese medicine composition raw material is preferably: Moschus 3-5 part, Radix Salviae Miltiorrhizae 20-40 part, Sanguis Draxonis 24-48 part, Radix Rehmanniae Preparata 15-25 part, Colla cornus cervi 8-12 part, Radix Aconiti Lateralis Preparata 8-12 part, Radix Codonopsis 8-12 part, Radix Glycyrrhizae 8-12 part, Poria cum Radix Pini 8-12 part, Semen Ziziphi Spinosae 8-12 part, Massa Medicata Fermentata (Massa Medicata Fermentata) 8-12 part.
The part by weight compatibility optimum of this invention Chinese medicine composition raw material is:: 4 parts, Moschus, 30 parts of Radix Salviae Miltiorrhizaes, 36 parts of Sanguis Draxonis, 20 parts of Radix Rehmanniae Preparata, 10 parts of Colla cornus cervis, 10 parts of Radix Aconiti Lateralis Preparata, 10 parts of Radix Codonopsis, 10 parts, Radix Glycyrrhizae, 10 parts of Poria cum Radix Pinis, 10 parts of Semen Ziziphi Spinosaes, 10 parts of Massa Medicata Fermentata.
The preparation method of this invention Chinese medicine composition is the weight according to the raw material of main effective ingredient, and the weight of getting above-mentioned raw materials was processed into respectively the powder of 120 mesh sieves, after oven dry, saved backup.
Get standby powder and carry out proportioning by the part by weight of the raw material of the main effective ingredient of Chinese medicine composition.
Make respectively tablet, pill, capsule, the dosage forms such as powder.
Make each medicine produce synergism these drug regimens, thus consciousness-restoring and orifice-opening more effectively, blood circulation promoting and blood stasis dispelling, spleen invigoratingization is turbid, tonifies Qi of the kidney, and reaches the purpose for the treatment of and pre-anti-dazzle, apoplexy, dementia, cerebral infarction, cerebral thrombosis.
Selected Moschus has consciousness and resuscitation restoring, promoting blood circulation to restore menstrual flow, the effect of pain relieving.The GUIXIN spleen channel.The main fragrance ingredient of Moschus is muscone and nitrogen-containing compound, cholesterol, fatty acid and inorganic salt etc.Low dose of Moschus and muscone are excitation to the central nervous system, and heavy dose can suppress, and can alleviate significantly cerebral edema, strengthen the toleration of central nervous system to anoxia, improve cerebral circulation.Isolated heart is had to excitation, increase coronary artery blood flow.Artificial or natural Moschus's ketone has to anesthetized cat boosting and increases the effect of respiratory frequency.Moschus all is appreciable stimulating action in vitro and uterus in place, and the latter is more responsive, and gravid uterus is more non-gravid uterus sensitivity again.The diluent of musk tincture, can suppress escherichia coli, staphylococcus aureus, hog cholera bacterium in vitro.Antiinflammatory action is arranged.This product all shows tumor cell had to inhibitory action the tissue homogenate culture fluid of human body esophageal squamous cell carcinoma, adenoma of stomach, colon cancer, bladder cancer, and concentration greatly acts on by force.
Radix Salviae Miltiorrhizae has promoting blood flow to regulate menstruation, removing heat from blood eliminating carbuncle, the effect of calming the nerves.GUIXIN, Liver Channel.Radix Salviae Miltiorrhizae energy coronary artery dilating, increase coronary flow, improves myocardial ischemia, promotes the recovery of myocardial ischemia or damage, dwindles myocardial infarct size; Can improve hypoxia-bearing capability, hypoxic cardiac muscle is had to protective effect; Can improve microcirculation, promote velocity of blood flow; The energy blood vessel dilating, reduce blood pressure.Can improve hemorheological property, reduce blood viscosity, anticoagulant and coagulation function, activate fibrinolytic, antagonism thrombosis; Can protect erythrocyte membrane.Can regulate blood fat, suppress the formation of atheromatous plaque.Can protect hepatocyte injury, promote liver cell regeneration, effect of anti hepatic fibrosis is arranged.Can promote the healing of fracture and skin incision.Can protect gastric mucosa, anti-gastric-ulcer.Nervus centralis is had to calmness and analgesic activity.There is the effect that improves renal function, protection Ischemic kieney injury.There is antiinflammatory, antianaphylactic effect.Staphylococcus aureus, multiple bacillus, some tinea bacterium and leptospira etc. are had to inhibitory action in various degree.
Sanguis Draxonis has the effect of the analgesic therapy of invigorating blood circulation, removing stasis to stop bleeding, expelling pus and promoting granulation.Return Liver Channel.Sanguis Draxonis is containing compositions such as dracorhodin, dracorubin, demethyl dracorhodin, demethyl dracorubins.Sanguis Draxonis water decoction-alcohol sedimentation liquid can obviously reduce packed cell volume, shortens plasma recalcification time, and anticoagulant, prevent thrombosis.Water extraction liquid has inhibitory action in various degree to Staphyloccocus aureus, Staphylococcus albus and multiple pathomycete.In addition, also has certain antiinflammatory action.
Radix Rehmanniae Preparata has the effect of the yin nourishing of enriching blood, life essence-filling, marrow-benefitting.Return liver, kidney channel.Radix Rehmanniae Preparata is containing catalpol, rehmanin, mannitol, retinoid material, saccharide and aminoacid etc.Radix Rehmanniae can be resisted the decline of taking continuously plasma corticosterone concentration after dexamethasone, and can prevent Adrenal cortex atrophy.Radix Rehmanniae decoct gavage can significantly reduce the ascorbic content of Rat Adrenal.Visible Radix Rehmanniae has the inhibitory action of antagonism dexamethasone to Pituitary Adrenal cortex system, and can promote the synthetic of adrenocortical hormone.
Colla cornus cervi has the effect of invigorating the liver and kidney, benefiting essence-blood.Return liver, kidney channel.Isolate estradiol, cholesterol etc. from the liposoluble constituent of Cornu Cervi Pantotrichum, the main component that wherein estradiol and metabolite-estrone in vivo thereof are the Cornu Cervi Pantotrichum estrogen-like effects.Aminoacid in Cornu Cervi Pantotrichum, the abundantest with glycine content, also contain neutral sugar, glucamine, contain calcium, phosphorus, magnesium etc. in the Cornu Cervi Pantotrichum ash, contain the volume colloid in water extraction.Heavy dose of pantocrine dwindles heart contracting amplitude, decreased heart rate, and make peripheral blood vessel expansion, Blood pressure drop.The median dose pantocrine causes the movable obviously enhancing of isolated heart, and heart contracting amplitude increases, and heart rate is accelerated, and result all increases heart pulse output and percentage output.
Radix Aconiti Lateralis Preparata has recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, the effect of dispersing cold for relieving pain.GUIXIN, kidney, spleen channel.Radix Aconiti Lateralis Preparata is containing aconitine, mesaconitine, hypaconitine, different delphinine, Xin Wuning alkali, black amine and uracil etc.Radix Aconiti Lateralis Preparata decoct, water-soluble portion etc., to the frog, Bufo siccus and homoiothermic animal heart, no matter be normal condition or in depletion, obvious cardiotonic all arranged; Its n-butanol extract, ethanol extraction and water extract quiver preventive effect are arranged chloroform induced mice chamber; Radix Aconiti Lateralis Preparata has significant antiinflammatory action, can suppress rat paw edema due to Ovum Gallus domesticus album, carrageenin, formaldehyde etc., suppresses due to acetic acid capillary permeability hyperfunction, suppresses Granuloma formation and adjuvant-induced arthritis; Mesaconitine, aconitine and hypaconitine all have analgesic activity.Study and show recently, Radix Aconiti Lateralis Preparata energy enhancing body oxidation resistance, have anti-aging effects.
Radix Codonopsis has the spleen reinforcing lung qi, enriches blood, the effect of promoting the production of body fluid.Return spleen, lung meridian.Radix Codonopsis is containing sterol, tangshenoside, Radix Codonopsis polysaccharide, codonolactone, alkaloid, inorganic elements, aminoacid, trace element etc.Radix Codonopsis energy Gastrointestinal motility adjustment, antiulcer, enhancing immunologic function; To excited all influential with two kinds of nervous process of inhibition; The Radix Codonopsis saponin can also excited respiratory center; Animal is had to of short duration hypotensive effect, but can make the blood pressure of hemorrhagic shock in rabbits in late period go up; The rabbit blood glucose that can significantly raise, its blood glucose increasing effect is relevant with contained sugar; Animal erythrocyte, hemoglobin, reticulocyte can raise; Also have the effects such as slow down aging, anti-hypoxia, radioprotective.
Radix Glycyrrhizae has invigorating the spleen and replenishing QI, removes phlegm and relieving cough, the function of relieving spasm to stop pain, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.GUIXIN, lung, spleen, stomach warp.Radix Glycyrrhizae is containing compositions such as triterpenes, flavonoid, alkaloid, polysaccharide.Radix Glycyrrhizae has anti-arrhythmia effect; Antiulcer is arranged, and gastric acid secretion inhibiting, alleviate gastrointestinal smooth muscular spasm and analgesic activity, and with the effective ingredient peoniflorin of Radix Paeoniae, synergism arranged; Can promote pancreatic secretion; Obvious antitussive effect is arranged, and phlegm-dispelling functions is also more remarkable, also has certain antiasthmatic effect; Antibiotic, antiviral, antiinflammatory, anti-allergic effects are arranged; Can protect throat and the tunica mucosa tracheae of inflammation; Some poisonous substance is had to the Detoxication of similar glucuronic acid; The effect of similar adrenocortical hormone sample is arranged; The effect such as also have diuresis, blood fat reducing, protect the liver.
Poria cum Radix Pini has promoting diuresis to eliminate damp pathogen, spleen invigorating, the effect of mind calming.GUIXIN, spleen, kidney channel.Poria, containing β-pachyman, accounts for approximately 93 % of dry weight, separately containing pachymic acid, protein, fat, lecithin, choline, histidine, ergosterol etc.Poria decoct, syrup, alcohol extract, ether extract, have respectively the effect of diuresis, calmness, antitumor, blood sugar lowering, increase myocardial contraction.Pachyman has the effect that strengthens immunologic function.Poria has liver protection effect, can reduce gastric secretion, gastric ulcer is had to inhibitory action.Semen Ziziphi Spinosae has the liver benefiting of nourishing heart, calms the nerves, and arresting sweating, the effect of promoting the production of body fluid.GUIXIN, liver, gallbladder meridian.
Semen Ziziphi Spinosae is containing saponin, and it consists of jujuboside A and B.And containing triterpenoid compound and flavone compound.In addition, containing significant quantities of fat oil and several amino acids, vitamin C, polysaccharide and plant sterol etc.Jujuboside, flavonoid glycoside, water and alcohol extract have respectively tranquilizing soporific and antiarrhythmic effect, and can work in coordination with the central inhibitory action of barbiturate; Its decocting liquid and alcohol extract also have convulsion, analgesia, body-temp. reducing, hypotensive effect; In addition, Semen Ziziphi Spinosae also has blood fat reducing, anti-hypoxia, antitumor, anticoagulant, strengthens immunologic function and the effect of excited uterus.
Massa Medicata Fermentata (Massa Medicata Fermentata) has the effect of the stomach function regulating that helps digestion.Return spleen, stomach warp.Massa Medicata Fermentata is yeast preparation, containing yeast, amylase, vitamin B complex, ergosterol, protein and fat, volatilization wet goods.Massa Medicata Fermentata, because containing volume yeast and compound vitamin B, therefore appetite stimulator is arranged, maintains the effects such as normal stool function.
Comprehensive each performance of medicine-feeding is not difficult to find out that this invention Chinese medicine composition has strengthening vital QI to eliminate pathogenic factors, the characteristics for the treatment of both the principal and the secondary aspects of a disease at the same time, and the while has been used again the basic principle of Chinese medicine determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, adopts the method for the treatment of different diseases with the same therapeutic principle; Combine the etiology and pathogenesis of dizzy, apoplexy, dementia, and the comprehensive syndrome of this disease; Then just draft prescription, prescription has passed through again a large amount of clinical practices after determining, uses continuously and sums up, and has proved this invention Chinese medicine composition, can be used for the treatment of dizzy, apoplexy, dementia fully.
This invention Chinese medicine composition is prepared according to the Chinese medicine principle, from solving, impact is dizzy, the etiology and pathogenesis of the genesis of apoplexy, dementia is set about, under the principle of Chinese medicine determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs instructs, conscientiously study the common feature of three diseases, think that the disease position is at brain, at clear key; Characteristic of disease is that empty or empty folder is real; The cause of disease is with old, QI and blood deficiency, and the overstrain internal injury, deficiency of kidney-essence and damaged by excess of seven emotions, add again the factor such as zang-fu disharmony relevant.Because QI and blood is contrary disorderly, brain arteries and veins impatency, the brain inanition, marrow subtracts brain and disappears, and that the pathogenesis such as refreshing machine apraxia cause is dizzy, the generation of apoplexy, dementia.Several different diseases, in its carcinogenesis of human, roughly the same etiology and pathogenesis occurred, and roughly the same syndrome, therefore can treat with roughly the same method for the treatment of and square medicine.Under the guidance of this theory of differentiation of tcm, the spy has worked out this invention Chinese medicine composition, can reach the purpose of dizzy, the apoplexy for the treatment of, dementia.This invention Chinese medicine composition belongs to pure Chinese medicinal preparation, without the chemicals composition, taking convenience is arranged, and easily absorbs, and has no side effect, effective, the characteristics of instant effect.By clinical observation for many years, prove, this invention Chinese medicine composition has consciousness-restoring and orifice-opening, blood circulation promoting and blood stasis dispelling, and spleen invigoratingization is turbid, and the effect of tonifying Qi of the kidney, have promotional value.
The specific embodiment
This invention Chinese medicine composition, used by outpatient service for many years, received good effect, once to patients with vertigo 191 examples, and stroke in convalescent stage patient 176 examples, dementia patients 94 examples, carried out the clinic trial statistics, good effect, the result statistics is as follows:
1, dizzy
The common symptom of 191 routine patients with vertigo is for having a dizzy spell, and weight differs, and the lighter is dim eyesight only, top-heavy or rock the sense of drifting along, and closes order and stops; Heavy as ship by bus, she depending on the thing rotation, very falls forward.Often with nausea and vomiting, pale complexion, cold extremities due to sweating, or tinnitus, sleep less, forgetful, order is puckery, the diseases such as soreness of the waist and knees.Stage of attack, is different in size, mostly is several months or several years outbreak once, also has January for several times.But sudden onset, also can increase the weight of gradually.
191 routine patients with vertigo are all by careful physical examination and routine blood test, electrocardiogram, transcranial doppler, the inspections such as CT, NMR, get rid of intracranial tumor, hematopathy and other can cause dizzy disease, all by Chinese Internal Medicine is dizzy, are diagnosed.
191 routine patients with vertigo, male 82 examples, female's 109 examples; 24 years old of age minimum, maximum 73 years old; The shortest 7 days of the course of disease, the longest 13 years; 56 examples that hypertension history is arranged, have 43 examples of diabetic history, 29 examples that blood fat is high; 191 routine patients all have the series of symptoms of above-mentioned vertigo, give respectively the treatment of this invention Chinese medicine composition, and result: take medicine 3 days, clinical cure person 22 examples, account for 11.5%; Take medicine 5 days, clinical cure person 29 examples, account for 15.2%; Take medicine 7 days, clinical cure person 45 examples, account for 23.6%; Take medicine 10 days, symptom 63 examples that are clearly better, account for 33%; Take medicine 15 days, 26 examples that partial symptoms is improved, account for 13.6%; 6 examples are separately arranged, due to older, body constitution is poor, the long relevant medical history such as hypertension that added again of the course of disease, takes this invention Chinese medicine composition invalid; Total effective rate is 96.9%; Follow up a case by regular visits to recurrence in 50 routine patient 1 year.
2, stroke in convalescent stage
176 routine paralytics are acute attack stage, by urgency, process 1-2 after week, have entered Recovery Phase of diseases, total symptom hemiplegia, and dyslalia, dispute is partially askew, hemianesthesia.The diseases such as, agitation heavy with headache and dizzy, head, singultus, the convalescent treatment of paralytic is fine or not, is determining the existence of patient latter half of one's life and the quality of life, so the Comprehensive Treatment of this phase is the key link.
176 routine patients pass through the system physical examination and CT, NMR check, are diagnosed as apoplexy, there is no and infect and other diseases.
1., 45 routine cerebral hemorrhage (Hitting Viscera) patients, male 29 examples, female's 16 examples; 45 years old of age minimum, maximum 65 years old; The shortest 6 days of the course of disease, the longest 16 days; Common symptom is hemiplegia, dyslalia, and dispute is partially askew, needs 2 people to help action; Age-based and men and women distinguishes tie in arrangement, is divided into 2 groups and carries out contrast therapy.
First group: 23 routine patients, in oral this invention Chinese medicine composition, accept acupuncture, massage, training Comprehensive Treatment, the time is decided to be 3 months, carries out efficacy evaluation; After accepting treatment in 3 weeks, have the partially askew symptom of 7 routine dispute to be clearly better, short word is pronounced distinctly, and by original 2 people, is helped and is become 1 people's support, accounts for 30.4%; After accepting treatment in 6 weeks, 4 grades of 11 routine Ipsilateral upper limb Myodynamia recoveries are arranged, the Ipsilateral lower-limb muscular strength recovers to approach 3 grades, the partially askew transference cure of dispute, and short word is pronounced distinctly, and can turn walking 5-10 rice by people's pestle, accounts for 47.8%; After accepting treatment in 10 weeks, have 5 routine Ipsilateral upper limb Myodynamia recoveries to approach 5 grades, the Ipsilateral lower-limb muscular strength recovers 3 grades, the partially askew transference cure of dispute, and speech phonation is normal, can turn independent walking by people's pestle, accounts for 21.7%; Total effective rate is 100%.
Second group: 22 routine patients adopt separately acupuncture, massage, training to be treated; After accepting treatment in 3 weeks, there is the partially askew symptom of 5 routine dispute to take a turn for the better, account for 22.7%; After accepting treatment in 6 weeks, have the partially askew symptom of 12 routine dispute to be clearly better, short word is pronounced distinctly, and the hemiplegia symptom makes moderate progress, and accounts for 54.5%; After accepting treatment in 10 weeks, have the partially askew symptom of 5 routine dispute substantially to disappear, short word is pronounced distinctly, and can turn 10 meters left and right of independent walking by people's pestle, accounts for 22.7%; Total effective rate is 100%.
First group is contrasted with second group, and the treatment of oral this invention Chinese medicine composition obviously is better than the treatment of second group.
2., 61 routine cerebral thrombosis (apoplex involving the channels and collaterals) patients, male 42 examples, female's 19 examples; 47 years old of age minimum, maximum 69 years old; The shortest 7 days of the course of disease, the longest 10 days; Symptom is hemiplegia, dyslalia, and retardation of thinking, with headache and dizzy, the symptoms such as feeling of fullness in the head, walk and need 1 people to assist in; Treat respectively 3 months, added up a course for the treatment of.
First group: 15 routine patients, can not accept Comprehensive Treatment in hospital because of home background, alone this invention Chinese medicine composition, coordinate and take 303 adenosine nutrition cranial nerve, result statistics, medication 2 weeks, headache and dizzy, feeling of fullness in the head transference cure; Medication 30 days, the retardation of thinking symptom is clearly better, and can turn walking by the independent pestle of a people; After medication 3 months, the energy independent ambulation, gait is walked lamely.
Second group: 46 routine patients, accept acupuncture, massage, training treatment, 11 examples are arranged, headache and dizzy after 15 days, the feeling of fullness in the head remission, account for 23.9%; 18 examples are arranged, headache and dizzy after 30 days, the feeling of fullness in the head transference cure, the retardation of thinking doing well,improving, can turn walking by the independent pestle of a people, accounts for 39.1%; 10 examples are arranged, and after 3 months, it is normal that verbal thought recovers, the energy independent ambulation, and gait is walked lamely, and accounts for 21.7%; 7 examples are separately arranged, and walking is appointed can not break away from cane, accounts for 15.2%.
First group is contrasted with second group, and the treatment of oral this invention Chinese medicine composition obviously is better than second group of traditional treatment.
3., 70 routine cerebral infarction (apoplex involving the channels and collaterals) patients, male 47 examples, female's 23 examples; 43 years old of age minimum, maximum 76 years old; The shortest 3 days of the course of disease, the longest 3 months; Symptom has hemiplegia, shows as the Ipsilateral upper and lower extremities unable, walks and walks lamely; Speech and retardation of thinking; With headache and dizzy, the phenomenons such as feeling of fullness in the head.Heal with medicine respectively:
First group: 33 routine patients, adopt the combined treatments such as this invention Chinese medicine composition and 303 adenosines, 7 examples are arranged, after taking medicine 7 days, headache and dizzy, the feeling of fullness in the head transference cure, account for 21.2%; 15 examples are arranged, and after taking medicine 20 days, it is normal that verbal thought recovers, and accounts for 45.5%; 9 examples are arranged, and after taking medicine 45 days, the Ipsilateral upper extremity function recovers substantially, accounts for 27.3%; 2 routine symptoms are arranged without improvement, account for 6.1%.
Second group: 37 routine patients, adopt NAOXINTONG, aspirin, 303 adenosine medicine combined treatments, 8 examples are arranged, after taking medicine 7 days, above-mentioned symptom, without improvement, accounts for 21.6%; 14 examples are arranged, after taking medicine 20 days, headache and dizzy, the feeling of fullness in the head transference cure, account for 37.8%; 12 examples are arranged, and after taking medicine 45 days, it is normal that verbal thought recovers, and the Ipsilateral upper extremity function recovers substantially, accounts for 32.4%; 3 routine symptoms are arranged without improvement, account for 8.1%.
First group is contrasted with second group, and the treatment of oral this invention Chinese medicine composition obviously is better than the treatment of second group.
4., according to this invention Chinese medicine composition each medicine coordinative role and effect, my Out-patient Department once suffers from hypertensive patient to 50 examples and gives to take continuously for 3 years, follow up a case by regular visits to none routine patient apoplexy occurs, absolutely prove that this invention Chinese medicine composition can improve brain blood and supply, guarantee the blood oxygen supply of brain abundance, having of cerebral thrombosis and cerebral infarction prevented and retarding action.
3, dementia
94 routine dementia patients, symptom with dizziness, tinnitus, have a dull expression on one's face, being reticent, memory and computing power obviously go down, agnosia is miscalculated, ability to speak is ambiguous, the language fails to express the meaning, goes out not know homeward journey, companion's soreness of the waist and knees, walking is difficult, lack of appetite is indigestion and loss of appetite, involuntary drooling etc.94 routine patients all check by neuropsychologic examination and CT, NMR, get rid of other relevant diseases, by treatment, within 12 months, are a cycle accumulative total, are added up:
94 routine patients, male 52 examples, female's 42 examples; 57 years old of age minimum, maximum 81 years old; The shortest 5 years of the course of disease, the longest 15 years; Take this invention traditional Chinese medicine composition for treating 3 months, 35 examples of doing well,improving, account for 37.2%; Take 6 months, 67 examples of doing well,improving, account for 71.3%; Adhere to taking 9-12 month, clinical cure 20 examples, account for 21.3%; 7 invalid examples, account for 7.4%; Total effective rate 92.6%.
embodiment
A kind of have a consciousness-restoring and orifice-opening, blood circulation promoting and blood stasis dispelling, and spleen invigoratingization is turbid, and can be used for of the effect of tonifying Qi of the kidney, treated the Chinese medicine composition of dizzy, apoplexy, dementia, and the part by weight compatibility of raw material for preparing the main effective ingredient of this medicine is:
This invention Chinese medicine composition preparation method is, selects the high-quality Chinese herb, by the part by weight of the raw material of the main effective ingredient of this invention Chinese medicine composition, is processed into respectively the powder of 120 mesh sieves, puts in calorstat and dries, and packing and storing is standby respectively.
Adopt one-shot or many stampings mechanism to make the tablet of different size; Adopt multi-functional pellet processing machine to be made into the pill of different size; Adopt fully-automatic capsule filling machine to be made into the capsule of different size; Powder after processing is carried out to proportioning by the part by weight of the raw material of this invention Chinese medicine composition, powder.
Claims (4)
1. a Chinese medicine composition that is used for the treatment of dizzy, apoplexy, dementia, the part by weight compatibility of raw material that it is characterized in that preparing the main effective ingredient of this medicine is: Moschus 2-6 part, Radix Salviae Miltiorrhizae 10-50 part, Sanguis Draxonis 12-60 part, Radix Rehmanniae Preparata 7-35 part, Colla cornus cervi 3-15 part, Radix Aconiti Lateralis Preparata 3-15 part, Radix Codonopsis 3-15 part, Radix Glycyrrhizae 3-15 part, Poria cum Radix Pini 3-15 part, Semen Ziziphi Spinosae 3-15 part, Massa Medicata Fermentata 3-15 part.
2. Chinese medicine composition according to claim 1, the part by weight compatibility of raw material that it is characterized in that preparing the main effective ingredient of this medicine is: Moschus 3-5 part, Radix Salviae Miltiorrhizae 20-40 part, Sanguis Draxonis 24-48 part, Radix Rehmanniae Preparata 15-25 part, Colla cornus cervi 8-12 part, Radix Aconiti Lateralis Preparata 8-12 part, Radix Codonopsis 8-12 part, Radix Glycyrrhizae 8-12 part, Poria cum Radix Pini 8-12 part, Semen Ziziphi Spinosae 8-12 part, Massa Medicata Fermentata 8-12 part.
3. Chinese medicine composition according to claim 1 and 2, the part by weight compatibility of raw material that it is characterized in that preparing the main effective ingredient of this medicine is: 4 parts, Moschus, 30 parts of Radix Salviae Miltiorrhizaes, 36 parts of Sanguis Draxonis, 20 parts of Radix Rehmanniae Preparata, 10 parts of Colla cornus cervis, 10 parts of Radix Aconiti Lateralis Preparata, 10 parts of Radix Codonopsis, 10 parts, Radix Glycyrrhizae, 10 parts of Poria cum Radix Pinis, 10 parts of Semen Ziziphi Spinosaes, 10 parts of Massa Medicata Fermentata.
4. the preparation method of the described Chinese medicine composition of claim 1-3 any one comprises the following steps:
1. material choice and processing: select the high-quality Chinese crude drug to remove impurity, be processed into respectively the powder of 120 mesh sieves by the weight of the raw material of Chinese medicine composition;
2. the powder after processing is carried out to proportioning by the part by weight of the raw material of this invention Chinese medicine composition, gets above-mentioned each medicamental pulverata, respectively processing in flakes, ball, capsule, powder type.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310453940.1A CN103495001A (en) | 2013-09-29 | 2013-09-29 | Traditional Chinese medicine composition for treating dizziness, stroke and dementia disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310453940.1A CN103495001A (en) | 2013-09-29 | 2013-09-29 | Traditional Chinese medicine composition for treating dizziness, stroke and dementia disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103495001A true CN103495001A (en) | 2014-01-08 |
Family
ID=49860323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310453940.1A Pending CN103495001A (en) | 2013-09-29 | 2013-09-29 | Traditional Chinese medicine composition for treating dizziness, stroke and dementia disease |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103495001A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108187020A (en) * | 2018-03-22 | 2018-06-22 | 广西中医药大学 | A kind of preparation method of Chinese medicine preparation and its application in vertigo is treated |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1273854A (en) * | 1999-05-15 | 2000-11-22 | 张德美 | Chinese medicine for treating cardiovascular disease |
| CN101057940A (en) * | 2007-05-31 | 2007-10-24 | 徐明波 | Apoplexy recover pills |
| CN101181533A (en) * | 2007-12-10 | 2008-05-21 | 张洪勇 | Chinese traditional medicine for curing brain angiocardiopathy |
| CN101385815A (en) * | 2007-09-14 | 2009-03-18 | 尹克华 | Traditional Chinese medicine for treating dementia after stroke |
| CN101773632A (en) * | 2010-04-19 | 2010-07-14 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicine composition for treating dizziness and preparation method thereof |
| CN102335396A (en) * | 2011-10-12 | 2012-02-01 | 成都绿迪科技有限公司 | Orally administered traditional Chinese medicine for treating senile dementia |
-
2013
- 2013-09-29 CN CN201310453940.1A patent/CN103495001A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1273854A (en) * | 1999-05-15 | 2000-11-22 | 张德美 | Chinese medicine for treating cardiovascular disease |
| CN101057940A (en) * | 2007-05-31 | 2007-10-24 | 徐明波 | Apoplexy recover pills |
| CN101385815A (en) * | 2007-09-14 | 2009-03-18 | 尹克华 | Traditional Chinese medicine for treating dementia after stroke |
| CN101181533A (en) * | 2007-12-10 | 2008-05-21 | 张洪勇 | Chinese traditional medicine for curing brain angiocardiopathy |
| CN101773632A (en) * | 2010-04-19 | 2010-07-14 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicine composition for treating dizziness and preparation method thereof |
| CN102335396A (en) * | 2011-10-12 | 2012-02-01 | 成都绿迪科技有限公司 | Orally administered traditional Chinese medicine for treating senile dementia |
Non-Patent Citations (1)
| Title |
|---|
| 贺清义等: "老年性痴呆病治验", 《四川中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108187020A (en) * | 2018-03-22 | 2018-06-22 | 广西中医药大学 | A kind of preparation method of Chinese medicine preparation and its application in vertigo is treated |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103169928B (en) | Externally applied traditional Chinese medicine composition for treating dysmenorrhea, as well as preparation method and application thereof | |
| CN102078520A (en) | Chinese medicinal preparation for treating nervous headache and preparation method thereof | |
| CN102526326B (en) | Traditional Chinese medicine for treating postmenopausal osteoporosis and preparation method thereof | |
| CN101632750B (en) | Chinese medicinal composition for replenishing essence, filling marrow, boosting kidney and strengthening yang and preparation method thereof | |
| CN104138550A (en) | Preparation method of medicine for treating peptic ulcers | |
| CN103705751B (en) | Chinese medicine composition being used for the treatment of lumbago due to pathogenic wind-dampness and preparation method thereof | |
| CN101780186B (en) | Medicine for curing brain dysfunction caused by traumatic brain injury | |
| CN104825914A (en) | Traditional Chinese medicinal preparation for assisted treatment of breast cancer | |
| CN101700336B (en) | Chinese herba preparation for curing craniocerebra trauma residual headache and preparation method | |
| CN104013817A (en) | Conic gymnadenia tuber-sealwort-radix polygonati officinalis preparation and production method thereof | |
| CN102406799A (en) | Cataplasm paste for treating diabetes and hypertension complicated with coronary heart disease and preparation method thereof | |
| CN101810843B (en) | Medicament for treating nerve system diseases such as cerebrovascular accident, spinal cord injury and senile dementia | |
| CN101195003B (en) | Proprietary Chinese medicine for treating apoplexy and sequela | |
| CN103495001A (en) | Traditional Chinese medicine composition for treating dizziness, stroke and dementia disease | |
| CN101543611B (en) | Traditional Chinese medicine for treating hysteria | |
| CN104352973A (en) | Chinese patent medicine for postpartum depression | |
| CN104324134A (en) | Traditional Chinese medicine composition for improving microcirculation and preparation method of traditional Chinese medicine composition | |
| CN102423367B (en) | Beautifying and blood-activating medicament | |
| CN102688365B (en) | Ginkgo Chinese medicinal oral liquid for treating dizziness and preparation method thereof | |
| CN101264302A (en) | Application of Chinese medicinal composition in preparing medicaments for treating menoxenia and menorrhalgia | |
| CN106075175A (en) | A kind of oral liquid treating insomnia forgetfulness and preparation method thereof | |
| CN106177520A (en) | A kind of Chinese medicine formula of Radix Codonopsis blood pressure lowering | |
| CN104666952B (en) | A kind of Chinese medicine composition for the treatment of chronic rhinitis and preparation method thereof | |
| CN104383441A (en) | Method for preparing Chinese patent medicine for treating postpartum depression | |
| CN104825846A (en) | Traditional Chinese medicinal composition for treating facial neuritis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20140108 |