CN103458899A - 治疗阻塞性睡眠呼吸暂停的方法 - Google Patents

治疗阻塞性睡眠呼吸暂停的方法 Download PDF

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Publication number
CN103458899A
CN103458899A CN2012800065522A CN201280006552A CN103458899A CN 103458899 A CN103458899 A CN 103458899A CN 2012800065522 A CN2012800065522 A CN 2012800065522A CN 201280006552 A CN201280006552 A CN 201280006552A CN 103458899 A CN103458899 A CN 103458899A
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CN
China
Prior art keywords
sleep
osa
pharmaceutical composition
pyridostigmine
apnea
Prior art date
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Pending
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CN2012800065522A
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English (en)
Chinese (zh)
Inventor
樊建强
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PFANTASTIC MEDICAL RESEARCH INSTITUTE LLC
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PFANTASTIC MEDICAL RESEARCH INSTITUTE LLC
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Application filed by PFANTASTIC MEDICAL RESEARCH INSTITUTE LLC filed Critical PFANTASTIC MEDICAL RESEARCH INSTITUTE LLC
Priority to CN201610821591.8A priority Critical patent/CN107007602A/zh
Publication of CN103458899A publication Critical patent/CN103458899A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
    • A61F5/56—Devices for preventing snoring
    • A61F5/566—Intra-oral devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nursing (AREA)
  • Otolaryngology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2012800065522A 2011-01-28 2012-01-27 治疗阻塞性睡眠呼吸暂停的方法 Pending CN103458899A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610821591.8A CN107007602A (zh) 2011-01-28 2012-01-27 治疗阻塞性睡眠呼吸暂停的方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161437272P 2011-01-28 2011-01-28
US61/437,272 2011-01-28
PCT/US2012/022825 WO2012103398A2 (en) 2011-01-28 2012-01-27 Methods for treating obstructive sleep apnea

Related Child Applications (1)

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CN201610821591.8A Division CN107007602A (zh) 2011-01-28 2012-01-27 治疗阻塞性睡眠呼吸暂停的方法

Publications (1)

Publication Number Publication Date
CN103458899A true CN103458899A (zh) 2013-12-18

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CN2012800065522A Pending CN103458899A (zh) 2011-01-28 2012-01-27 治疗阻塞性睡眠呼吸暂停的方法
CN201610821591.8A Pending CN107007602A (zh) 2011-01-28 2012-01-27 治疗阻塞性睡眠呼吸暂停的方法

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Country Link
US (2) US8753327B2 (enExample)
EP (1) EP2672972B1 (enExample)
JP (2) JP2014503593A (enExample)
CN (2) CN103458899A (enExample)
CA (1) CA2825309C (enExample)
WO (1) WO2012103398A2 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110198688A (zh) * 2016-12-23 2019-09-03 皇家飞利浦有限公司 用于处置至少两个用户间的打鼾的系统
CN110799181A (zh) * 2017-04-28 2020-02-14 布里格姆妇女医院 用于治疗睡眠呼吸暂停的方法和组合物
CN114504643A (zh) * 2021-12-24 2022-05-17 北京大学第一医院 抗IgE抗体在用于治疗OSAS中的应用
US11911351B2 (en) 2018-01-30 2024-02-27 Apnimed, Inc. (Delaware) Methods for treating sleep apnea with combinations of atomoxetine and (R)-oxybutynin
US12558327B2 (en) 2019-02-08 2026-02-24 The Brigham And Women's Hospital, Inc. Methods and compositions for treating sleep apnea

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2672972B1 (en) * 2011-01-28 2020-11-04 Pfantastic Medical Research Institute, LLC Methods for treating obstructive sleep apnea
JP2017506929A (ja) * 2014-03-03 2017-03-16 スリープ イノベイションズ プロプライアタリー リミティド 睡眠時無呼吸治療の装置及び方法
WO2016014229A1 (en) 2014-07-25 2016-01-28 Mendelowitz David Oxytocin improves treatment of obstructive sleep apnea
JP6480598B2 (ja) 2015-04-02 2019-03-13 ヒル−ロム サービシーズ プライヴェート リミテッド 呼吸装置用マニホールド
ES2861153T3 (es) * 2018-06-18 2021-10-05 Composiciones de liberación prolongada que comprenden piridostigmina
WO2020038900A1 (en) * 2018-08-24 2020-02-27 Koninklijke Philips N.V. Providing sleep therapy with a pressure therapy system
US11266837B2 (en) 2019-03-06 2022-03-08 Medtronic Xomed, Inc. Position sensitive lingual muscle simulation system for obstructive sleep apnea
CN120390613A (zh) * 2022-12-28 2025-07-29 西川株式会社 健康风险判定系统、自律神经判定系统、生活改善系统、睡姿判定系统、睡姿判定程序、磨牙检测系统及磨牙检测程序

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6034117A (en) * 1995-12-19 2000-03-07 A & Science Invest Ab Methods of treating and diagnosing sleep disordered breathing and means for carrying out the method

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2247662B (en) 1990-08-31 1994-11-02 Instance Ltd David J Labels and manufacture thereof
WO2005016327A2 (en) * 2003-08-13 2005-02-24 Janssen Pharmaceutica, N.V. Treatment of sleep disorders with cholinesterase inhibitors
CA2622721A1 (en) * 2005-09-16 2007-03-22 Cereuscience Ab Method and means of preventing and treating sleep disordered breathing
US20080066739A1 (en) * 2006-09-20 2008-03-20 Lemahieu Edward Methods and systems of delivering medication via inhalation
US7984714B2 (en) * 2006-09-29 2011-07-26 Nellcor Puritan Bennett Llc Managing obstructive sleep apnea and/or snoring using local time released agents
EP2672972B1 (en) * 2011-01-28 2020-11-04 Pfantastic Medical Research Institute, LLC Methods for treating obstructive sleep apnea

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6034117A (en) * 1995-12-19 2000-03-07 A & Science Invest Ab Methods of treating and diagnosing sleep disordered breathing and means for carrying out the method

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110198688A (zh) * 2016-12-23 2019-09-03 皇家飞利浦有限公司 用于处置至少两个用户间的打鼾的系统
CN110799181A (zh) * 2017-04-28 2020-02-14 布里格姆妇女医院 用于治疗睡眠呼吸暂停的方法和组合物
US11911351B2 (en) 2018-01-30 2024-02-27 Apnimed, Inc. (Delaware) Methods for treating sleep apnea with combinations of atomoxetine and (R)-oxybutynin
US12558327B2 (en) 2019-02-08 2026-02-24 The Brigham And Women's Hospital, Inc. Methods and compositions for treating sleep apnea
CN114504643A (zh) * 2021-12-24 2022-05-17 北京大学第一医院 抗IgE抗体在用于治疗OSAS中的应用
CN114504643B (zh) * 2021-12-24 2024-03-26 北京大学第一医院 抗IgE抗体在用于治疗OSAS中的应用

Also Published As

Publication number Publication date
WO2012103398A2 (en) 2012-08-02
CA2825309A1 (en) 2012-08-02
JP2017095485A (ja) 2017-06-01
CA2825309C (en) 2019-10-01
EP2672972A2 (en) 2013-12-18
WO2012103398A9 (en) 2012-09-27
US20140238412A1 (en) 2014-08-28
JP6342525B2 (ja) 2018-06-13
CN107007602A (zh) 2017-08-04
EP2672972B1 (en) 2020-11-04
US8753327B2 (en) 2014-06-17
JP2014503593A (ja) 2014-02-13
US20120197235A1 (en) 2012-08-02
EP2672972A4 (en) 2014-09-10
US9295670B2 (en) 2016-03-29

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Application publication date: 20131218

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