CN103444798A - Safe mosquito repellent containing bamboo wood vinegar liquid as well as preparation method and application thereof - Google Patents

Abstract

The invention discloses a safe mosquito repellent containing bamboo wood vinegar, a manufacturing method and application thereof. It is characterized in that it comprises the following raw materials and auxiliary materials in parts by weight: 20-80 parts of refined bamboo wood vinegar, 5-20 parts of plant essential oil, 1-20 parts of surfactant, 2-5 parts of DEET or 0.2 parts of pyrethroids -0.4 part, the refined bamboo wood vinegar is refined bamboo vinegar or refined wood vinegar or a mixture of two kinds, the refined bamboo wood vinegar is obtained by distillation or rectification of the bamboo wood vinegar stock solution The yield is less than 95% distillate. The invention uses natural bamboo (wood) vinegar as raw material, and adds proper amount of natural plant essential oil and surface active agent to the refined bamboo and wood vinegar after rectification and filtration until the liquid is clear and transparent. The mosquito repellent prepared by the invention is an environment-friendly product with safe use, low cost and high special effect.

Description

A kind of safe mosquito repellent containing bamboo wood vinegar and its manufacturing method and application

technical field

The invention relates to a natural plant extract, which is used to prevent mosquito bites, and belongs to the technical field of sanitation, in particular to a safe mosquito repellent containing bamboo and wood vinegar, its manufacturing method and application.

Background technique

Mosquitoes are called the number one killer in nature by the World Health Organization. They spread malaria, dengue fever, yellow fever, Japanese encephalitis and other diseases, threatening the health of hundreds of millions of people and causing the death of 1-3 million people every year. For example, in 2006, WHO estimated that malaria, transmitted by Anopheles gambiae, infected 250 million people and killed nearly a million people, mostly children in Africa. Even in the developed United States, the West Nile virus, carried by mosquitoes, has caused panic. The first human infection with West Nile virus occurred in New York in 1999. In 2008, there were more than 1370 human cases of West Nile virus infection in the United States, and the cases of infection almost covered the continental United States. In 2009, dengue fever spread in Yiwu, Zhejiang, my country, causing national panic. It can be seen that the diseases transmitted by mosquitoes have brought disasters to mankind both in history and now. Even today, with the continuous development of science, this problem has not been overcome.

Mosquitoes not only threaten human health, but also do great harm to poultry, animal husbandry and other industries. For example, West Nile virus will cause a large number of deaths of birds and horses. However, many existing chemical insecticides are not effective, they not only lead to environmental pollution, but also have strong toxicity to non-target organisms, and also lead to the enhancement of mosquito resistance. For example, DDT was first synthesized by others in 1874. Dr. Miller discovered that this compound has mosquito-killing activity in 1939, and won the Nobel Prize in Physiology and Medicine in 1948, but later people found that DDT was very harmful to the ecological environment and stopped. production use. In recent years, there have been some research results and applications of plant-derived mosquitoicides, but there are also problems of safety and resistance. Some insect growth regulators have also achieved preliminary results, but they are mainly used in the control of agricultural pests, and they are still blank for sanitary pests. Because mosquitoes mainly rely on their sense of smell to find their biting targets, the study of mosquito olfactory disruptors has become a hot spot in international research, especially the study of the mosquito olfactory system. The most widely used mosquito smell disruptor is DEET. It is a mosquito repellent product developed by the US military in the last century. It was used in the army in 1946 and entered the market in 1956. Until today, it is still the mosquito repellent product with the largest market share. Although a large number of studies have shown that the toxicity of DEET is not high, other research data have shown that there are 6 cases of death caused by incorrect use, and other studies have shown that long-term use of DEET will have adverse effects on children's intelligence. DEET works mainly by applying it to the skin of the body. It is mainly used for personal mosquito repellent in the wild, and its use range is narrow.

Contents of the invention

The purpose of the present invention is to overcome the defects in the prior art, to provide a safe mosquito repellent containing bamboo wood vinegar and its manufacturing method and application, which has significant anti-mosquito effects, no pollution, no pollution, low toxicity, and is harmless to humans ( (including pregnant women and infants) are safe, the manufacturing process is environmentally friendly, the method of use is simple, the cost is low, and the dosage is low. It can be effectively applied to mosquito control in indoor and outdoor places such as homes and offices.

A safe mosquito repellent containing bamboo and wood vinegar, characterized in that it comprises the following raw materials and auxiliary materials in parts by weight: 20-80 parts of refined bamboo and wood vinegar, 5-20 parts of plant essential oil, and 1-20 parts of surfactant , 2-5 parts of DEET or 0.2-0.4 parts of pyrethroids, the refined bamboo and wood vinegar is refined bamboo vinegar or refined wood vinegar or a mixture of two, the refined bamboo and wood Vinegar refers to the distillate obtained by distilling or rectifying the stock solution of bamboo and wood vinegar with a yield of less than 95%.

The plant essential oil is one or a mixture of tea tree oil, eucalyptus oil, camphor tree oil, clove oil or citronella oil, and the surfactant is OP-10, Span 80 (SPAN), ten A mixture of one or more of dialkylbenzenesulfonic acid or Tween 80, and the permethrin is one of cypermethrin, permethrin, and allethrin.

The content of the plant essential oil is 5-12 parts.

The refined bamboo wood vinegar is 20-60 parts.

The surfactant is 1-10 parts.

The DEET is 2-4 parts or the pyrethroids is 0.2-0.3 parts.

A kind of manufacture method of safe mosquito repellent containing bamboo wood vinegar, its manufacture method is as follows:

(1) Add 20-80 parts of refined bamboo wood vinegar to the enamel reaction kettle, then slowly add 1-10 parts of surfactant to it, stir and dissolve completely, slowly add 3-12 parts of plant essential oil, and stir until the solution is uniform Stable, record as A liquid.

(2) Add 2-8 parts of plant essential oils into another enamel reaction kettle, and add 2-5 parts of DEET or 0.2-0.4 parts of pyrethroids under constant stirring until the solution is uniform and stable, which is recorded as liquid B.

(3) Under the action of constant stirring, slowly add liquid B into liquid A until the mixed solution is uniform and stable.

The invention is mainly used for preventing mosquitoes such as Aedes albopictus, Aedes aegypti, Culex palustris, Anopheles anthropophagus and Anopheles sinensis from biting.

Parts in this application document are percentages by weight.

This invention aims to develop bamboo wood vinegar into indoor use with the same efficacy as insecticide, and also can be used outdoors as a wide range of anti-mosquito products with significant effects like DEET. The beneficial effects of the present invention are as follows: 1) The original solution of bamboo and wood vinegar has a strong smoky taste, which is harmful to the health of humans and animals and has an unpleasant taste. Therefore, choosing refined bamboo and wood vinegar can remove harmful substances and smoky taste ; 2) Refined bamboo and wood vinegar has a certain effect of repelling mosquitoes and preventing mosquito bites. Industrialization enters the market, and the same is true for essential oils. Only by compounding refined bamboo and wood vinegar with essential oils using nanotechnology can its effect be increased; There is still a certain gap in the requirements (many users think that the product has no effect even if they are bitten by mosquitoes once after using the product, and the theoretical number of times a mosquito bites and attacks a person every night is 14 times, and there are 7 mosquitoes in the room. If the anti-efficacy of the drug reaches 98%, it will be bitten twice), and the effect reaches 98.0%, and it is difficult to satisfy consumers. Therefore, how to improve the effect to more than 99.5% will become the limit of whether the product can satisfy consumers; 4 ) The present invention also adds a small amount of polyester insecticides (equivalent to 10-40% of the traditional mosquito-repellent incense usage) like the traditional mosquito-repellent incense, which not only greatly reduces the toxicity, but also improves the safety of the product to humans and animals, and prevents The effect of mosquito bites is more than 99.0% under the synergy of bamboo wood vinegar and essential oil; 5) The present invention also has certain innovations in the manufacturing method, which is mainly manifested in that bamboo wood vinegar is not only a synergist , and given the role of solvent, the whole production method does not use traditional ethanol, acetone and other solvents, and through the method of secondary emulsification, the product can form a nano-scale uniform and stable liquid, which improves the effect and quality stability of the product.

Detailed ways

The present invention will be further described in detail by way of examples.

Example 1

Put 20 parts of refined wood vinegar into the enamel reaction kettle, then slowly add 1 part of surfactant OP-10 into it, stir and dissolve completely, then slowly add 3 parts of tea tree oil, stir until the solution is uniform and stable, record it as liquid A. Add 2 parts of tea tree oil into another enamel reaction kettle, and add 2 parts of DEET or 0.2 parts of pyrethroids under constant stirring until the solution is uniform and stable, which is recorded as liquid B. Under the action of constant stirring, slowly add liquid B to liquid A until the two solutions are clear, transparent, uniform and stable.

Example 2

Put 40 parts of refined bamboo vinegar into the enamel reaction kettle, then slowly add 10 parts of surfactant Span 80 (SPAN) into it, stir and dissolve completely, slowly add 6 parts of eucalyptus oil, stir until the solution is uniform and stable, record Make liquid A. Add 4 parts of eucalyptus oil into another enamel reaction kettle, and add 3 parts of DEET or 0.3 parts of pyrethroids under the condition of constant stirring until the solution is uniform and stable and recorded as liquid B. Under the action of constant stirring, slowly add liquid B to liquid A until the two solutions are clear, transparent, uniform and stable.

Example 3

Put 60 parts of refined bamboo (wood) vinegar into the enamel reaction kettle (including 40 parts of wood vinegar + 20 parts of bamboo vinegar), then slowly add 15 parts of surfactant dodecylbenzenesulfonic acid into it, and stir completely After dissolving, slowly add 9 parts of clove oil, stir until the solution is uniform and stable, and record it as liquid A. Add 6 parts of clove oil into another enamel reaction kettle, and add 4 parts of DEET or 0.4 parts of pyrethroids under the condition of constant stirring until the solution is uniform and stable, which is recorded as liquid B. Under the action of constant stirring, slowly add liquid B to liquid A until the two solutions are clear, transparent, uniform and stable.

Example 4

Put 80 parts of refined wood vinegar into the enamel reaction kettle, then slowly add 20 parts of surfactant Tween 80 into it, stir and dissolve completely, slowly add 12 parts of citronella oil, stir until the solution is uniform and stable, record it as liquid A . Add 8 parts of citronella oil into another enamel reaction kettle, and add 5 parts of DEET or 0.4 parts of pyrethroids under the condition of constant stirring until the solution is uniform and stable, which is recorded as liquid B. Under the action of constant stirring, slowly add liquid B to liquid A until the two solutions are clear, transparent, uniform and stable.

Example 5

Put 20 parts of refined bamboo vinegar into the enamel reaction kettle, then slowly add 1 kg of surfactant OP-10 and 1 kg of Span 80 (SPAN) into it, stir and dissolve completely, slowly add 3 parts of camphor tree oil, and stir until the solution is uniform Stable, record as A solution. Add 2 parts of camphor tree oil to another enamel reaction kettle, and add 3 parts of DEET or 0.2 parts of pyrethroids under the condition of constant stirring until the solution is uniform and stable and recorded as liquid B. Under the action of constant stirring, slowly add liquid B to liquid A until the two solutions are clear, transparent, uniform and stable.

Example 6

Put 50 parts of refined bamboo (wood) vinegar into the enamel reaction kettle (including 30 parts of wood vinegar + 20 parts of bamboo vinegar), and then slowly add surfactants such as dodecylbenzenesulfonic acid and Tween 80 5kg, after stirring to dissolve completely, slowly add 5kg of tea tree oil, stir until the solution is uniform and stable, record it as liquid A. Add 5 kg of camphor tree oil to another enamel reaction kettle, and add 4 parts of DEET or 0.3 parts of pyrethroids under the condition of constant stirring until the solution is uniform and stable and recorded as liquid B. Under the action of constant stirring, slowly add liquid B to liquid A until the two solutions are clear, transparent, uniform and stable.

Example 7

Put 80 parts of refined bamboo (wood) vinegar into the enamel reaction kettle (including 30 parts of wood vinegar + 50 parts of bamboo vinegar), and then slowly add surfactants dodecylbenzenesulfonic acid, OP-10 and 7kg each of Span 80 (SPAN), after stirring completely to dissolve, slowly add 10kg of citronella oil, stir until the solution is uniform and stable, record it as solution A. Add 10kg of clove oil into another enamel reaction kettle, and add 5 parts of DEET or 0.4 parts of pyrethroids under the condition of constant stirring until the solution is uniform and stable and recorded as liquid B. Under the action of constant stirring, slowly add liquid B to liquid A until the two solutions are clear, transparent, uniform and stable.

Illustrate the preventive effect of above-mentioned invention product by test below.

Table 1. Control effect of Aedes albopictus (corrected control effect %, 95% confidence range)

1h after use 2h after use 4h after use 8 hours after use Example 1 65.8±3.2 76.6±2.2 93.2±4.2 95.3±5.0 Example 2 63.6±3.5 77.7±2.6 94.5±4.5 96.1±6.0 Example 3 67.6±4.2 75.3±2.7 92.2±4.8 97.7±5.4 Implementation 4 67.1±3.0 76.6±3.2 93.9±4.8 96.0±2.9

Example 5 75.3±2.9 87.1±3.1 97.7±4.6 99.1±3.6 Example 6 77.1±2.8 86.5±3.0 98.2±3.9 99.5±5.2 Example 7 76.7±2.6 85.9±3.2 98.6±5.0 99.8±6.0

The data in table 1 shows that embodiment 1-7 all reaches more than 60% to the corrected control effect of Aedes albopictus 1h, 2h all reaches more than 75%, 4h reaches more than 92%, the highest reaches 99.6%; 8h reaches more than 95%, wherein Embodiment 6-7 all reaches more than 99.5%, meets the high effect requirement of consumer.

Table 2. Control effect of Aedes aegypti (corrected control effect %, 95% confidence range)

1h after use 2h after use 4h after use 8 hours after use Example 1 60.9±2.3 73.9±4.6 91.3±2.3 92.5±3.6 Example 2 67.7±3.1 75.3±3.2 91.7±2.6 92.1±3.1 Example 3 66.3±2.0 73.1±3.3 90.5±3.0 91.9±2.8 Example 4 65.2±4.3 74.4±4.1 91.3±2.4 93.2±5.1 Example 5 79.5±2.6 87.6±2.9 95.5±4.0 99.8±4.5 Example 6 77.9±3.3 86.3±2.6 98.8±4.3 98.7±4.2 Example 7 78.5±3.1 88.5±4.3 96.5±3.9 97.8±3.7

According to table 2, it is shown that embodiment 1-7 all reaches more than 60% to the corrective control effect of Aedes aegypti 1h, 2h all reaches more than 73%, 4h reaches more than 90%, the highest reaches 98.8%; 8h reaches more than 91%, wherein Embodiment 6-7 all reaches more than 97.8%, meets the high effect requirement of consumer.

Table 3. Control effect of Culex palustris (corrected control effect %, 95% confidence range)

1h after use 2h after use 4h after use 8 hours after use Example 1 65.6±3.3 73.0±3.7 89.9±3.0 92.5±5.3 Example 2 67.4±4.3 74.5±4.0 90.0±3.2 91.7±2.9 Example 3 67.9±3.9 73.7±3.6 92.9±4.8 92.0±2.5 Example 4 66.0±2.8 74.8±3.4 92.8±2.9 93.7±2.5 Example 5 74.7±5.1 85.0±3.0 94.7±3.7 98.5±3.6 Example 6 75.8±5.3 83.6±2.9 94.3±4.0 97.9±4.2 Example 7 73.8±4.0 82.8±2.0 96.0±5.3 99.5±5.1

According to table 3, it is shown that embodiment 1-7 all reaches more than 60% to the corrected prevention and control effect of Culex palustris 1h, 2h all reaches more than 73%, 4h reaches more than 89%, the highest reaches 96.0%; 8h reaches more than 91%, wherein Embodiment 6-7 all reaches more than 99.5%, meets the high effect requirement of consumer.

Table 4. Control effect of Anopheles anthropophagus (corrected control effect %, 95% confidence range)

1h after use 2h after use 4h after use 8 hours after use Example 1 71.9±3.4 80.5±3.1 90.3±4.1 94.4±3.8 Example 2 69.9±3.6 79.5±2.8 89.1±4.0 93.5±2.9 Example 3 70.2±2.9 81.4±4.6 91.9±3.4 94.1±4.5 Example 4 71.8±4.0 79.8±3.1 90.8±3.6 95.7±3.1 Example 5 78.4±4.6 84.9±3.6 93.3±2.8 98.5±2.7 Example 6 79.6±2.6 85.1±2.5 95.5±4.2 99.9±4.0 Example 7 79.1±3.1 83.6±2.0 94.8±3.7 98.7±5.1

Table 4 shows that embodiment 1-7 all reaches more than 60% to the corrected control effect of Anopheles anthropophagus 1h, 2h all reaches more than 79%, 4h reaches more than 89%, the highest reaches 95.5%; 8h reaches more than 93%, Wherein embodiment 6-7 all reaches more than 99.9%, meets the high effect requirement of consumer.

Table 5. Control effect of Anopheles sinensis (corrected control effect %, 95% confidence range)

1h after use 2h after use 4h after use 8 hours after use Example 1 69.4±4.2 75.3±4.2 92.4±2.0 94.6±3.6 Example 2 67.9±2.9 73.5±3.8 94.7±2.5 96.3±4.3 Example 3 70.3±3.7 77.7±3.5 93.4±2.1 93.2±4.1 Example 4 71.3±2.6 75.8±4.1 92.1±3.5 95.8±5.2 Example 5 78.7±3.7 81.3±3.9 96.6±3.1 99.0±3.7 Example 6 78.2±3.3 80.6±2.8 95.0±3.0 98.4±3.5 Example 7 79.1±2.6 82.8±3.4 96.3±3.7 99.3±2.4

According to table 5, it is shown that embodiment 1-7 all reaches more than 60% to the correcting control effect of Anopheles sinensis 1h, and 2h all reaches more than 73%, and 4h reaches more than 92%, and the highest reaches 96.6%; 8h reaches more than 93%, wherein Embodiment 6-7 all reaches more than 99.3%, meets the high effect requirement of consumer.

Claims (8)

1. the safe culicifuge containing the bamboo pyroligneous liquor, it is characterized in that comprising that the raw material of following weight parts and auxiliary material form: refining bamboo pyroligneous liquor 20-80 part, plants essential oil 5-20 part, surfactant 1-20, Metadelphene DEET2-5 part or chrysanthemum ester class 0.2-0.4 part, described refining bamboo pyroligneous liquor is one or both the mixture in refined bamboo vinegar or acetum pyrolignosum rectificatum liquid, and this refining bamboo pyroligneous liquor productive rate that to be bamboo pyroligneous liquor stoste obtain through distillation or rectifying is lower than 95% distillate.

2. the safe culicifuge containing the bamboo pyroligneous liquor according to claim 1, it is characterized in that one or more the mixture that described plants essential oil is tea oil, eucalyptus oil, camphor tree oil, caryophyllus oil or citronella oil, described surfactant is OP-10, the 80(SPAN of department class), one or more the mixture in DBSA or Tween 80, described chrysanthemum ester class is a kind of in cypermethrin, Prallethrin, allethrin composition.

3. a kind of safe culicifuge containing the bamboo pyroligneous liquor according to claim 1, is characterized in that described plants essential oil content is 5-12 part.

4. a kind of safe culicifuge containing the bamboo pyroligneous liquor according to claim 1, is characterized in that described refining bamboo pyroligneous liquor is 20-60 part.

5. a kind of safe culicifuge containing the bamboo pyroligneous liquor according to claim 1, is characterized in that described surfactant is 1-10 part.

6. a kind of safe culicifuge containing the bamboo pyroligneous liquor according to claim 1, described DEET is that 2-4 part or chrysanthemum ester class are 0.2-0.3 part.

7. the manufacture method of a kind of safe culicifuge containing the bamboo pyroligneous liquor according to claim 1, its manufacture method is as follows:

(1) in enamel reaction still, add 20-80 part to make with extra care the bamboo pyroligneous liquor, then slowly add wherein 1-10 part surfactant, after stirring dissolving fully, slowly add 3-12 part plants essential oil, be stirred to solution uniform and stable, note is done A liquid.

(2) add 2-8 part plants essential oil in another enamel reaction still, in situation about constantly stirring, add DEET2-5 part or chrysanthemum ester class 0.2-0.4 part, do B liquid to the uniform and stable note of solution.

(3) under the effect of constantly stirring, B liquid is slowly added to A liquid until mixed solution is uniform and stable.

8. the purposes of a kind of safe culicifuge containing the bamboo pyroligneous liquor according to claim 1, is characterized in that aedes albopictus, Aedes aegypti, Culex pipiens pallens, have a liking for the people anopheles, Anopheles sinensis has prevention and bites function.