CN110495420B - Method for preventing and treating red mites of poultry - Google Patents
Method for preventing and treating red mites of poultry Download PDFInfo
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- CN110495420B CN110495420B CN201910707314.8A CN201910707314A CN110495420B CN 110495420 B CN110495420 B CN 110495420B CN 201910707314 A CN201910707314 A CN 201910707314A CN 110495420 B CN110495420 B CN 110495420B
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Abstract
The invention discloses a method for controlling red mites in poultry, which comprises feeding poultry with a first plant essential oil composition as a feed additive and applying a second plant essential oil composition as a spray to a poultry house; wherein the first plant essential oil composition comprises cinnamaldehyde, citronellal, carvacrol, eugenol, citral, linalool and a carrier, and the second plant essential oil composition comprises cinnamaldehyde, carvacrol, eugenol, citral, peppermint oil, eucalyptus oil and water; the invention not only can realize better killing of the red mites of poultry, especially chickens, but also overcomes the problems of drug resistance, pesticide residue, environmental pollution and the like in the prior art.
Description
Technical Field
The invention belongs to the field of poultry red mite resistance, and particularly relates to a method for preventing and treating poultry red mite.
Background
The red mites of poultry are also called dermanyssus gallinae, red chicken mites, perching mites, chicken mites and the like, are serious poultry ectoparasitic pests and are potential pathogenic vectors. The red mites usually climb to the chicken body at night to suck blood, and hide various gaps and cracks in the daytime; the red mites are widely prevalent in the world, and the prevalence rate is as high as 90%; the chickens suffering from the red mites are uneasy to appear, the feather pecking and anus pecking conditions are increased, good rest cannot be obtained, the sick chickens are emaciated and anaemic, the feed consumption is increased, the laying rate is reduced, and the death and culling rate is increased; and the red mites are the transmission media of various diseases at the same time, so that the harm is huge.
At present, red mites appear in chicken farms mainly by spraying pyrethrin or organic phosphorus and other chemicals, and the chemicals such as deltamethrin, cypermethrin and the like belong to highly toxic pesticides. However, the red mites have serious drug resistance to the pyrethrins, the dosage is not easy to control, the chickens are easy to be poisoned, the pesticide residues on eggs are heavy, even if the pesticide is sprayed, the red mites can be killed by touching the eggs by spraying the pesticide on the bodies of the chickens, and gaps are reserved in the chicken wings and wall seams and are difficult to spray in place, so that the effect of killing the red mites is poor.
In view of the above problems, it has also been proposed to kill red mites with active chemical disinfectant drugs, for example, chinese patent CN109221111A, which discloses a drug for treating poultry lice, the drug is prepared from the following raw materials in percentage by weight: 4% (C9-11 ethanol +8 mol ethylene oxide), 4.5% (quaternary ammonium compounds or dimethylbenzyl ammonium chloride or chloride), 3% didecyl dimethyl ammonium chloride, 0.9% cocoimido oxime glycinate, 1.5% N- (3-aminopropyl) -N-dodecyl-1, 3-propanediamine, 0.8% sodium carbonate, 0.02% 1, 2-benzisothiazol-3 (2H) -one, 6% (N-methyl glycine or N-methyl imino acetic acid or trisodium nitrilotriacetate), 0.3% lavender essence, water 78.98%. However, although the patent may achieve a good effect of killing red mites, the chemical substances used in the patent contain a large amount of halogen elements and are high in cost, which is not beneficial to large-scale application, and the application of a large amount of halogen elements can cause harm to the environment.
Currently, means for killing red mites by using conventional mite-killing essential oils or plant extracts are also proposed, for example, report 1, formula of essential oil: 5 drops of the eucalyptus essential oil, the tea tree essential oil and the rosemary essential oil are respectively added into mopping water to clean the floor, so that mites can be eliminated; also as reported 2, essential oil formulation: 5 drops of tea tree essential oil and lavender essential oil are respectively dropped on a paper towel (or a cotton ball) and placed in a wardrobe to remove mites; also, as reported in report 3, tea tree essential oil, lavender essential oil, eucalyptus essential oil were mixed with 5 drops each and dropped in warm water, and the bedding was immersed and washed to remove mites; also as reported in report 4, essential oil formulation: the eucalyptus essential oil is 10 drops, the rosemary essential oil is 10 drops, the lemon essential oil is 20 drops and the tea tree essential oil is 10 drops, and the eucalyptus essential oil and the alcohol are mixed and then sprayed to every corner of a room for mite removal; for another example, chinese patent CN107519072A discloses a formula of mite-killing essential oil, which comprises the following components in parts by weight: 35-45 parts of almond oil, 25-35 parts of tea tree essential oil, 10-15 parts of pure cinnamomum camphora leaf oil, 4-8 parts of cinnamon oil, 4-8 parts of anise oil, 4-8 parts of geranium oil, 4-8 parts of cinnamomum camphora tincture and 2-5 parts of ethanol; therefore, some essential oils or formulas are proposed to be used for killing the red mites on chicken flocks, but the effect is not ideal in practical application, and the essential oils or formulas are preliminarily considered to have a good effect on killing the poultry red mites because the red mites have extremely strong fertility and are spread very quickly and the living environment of the red mites is complex and variable.
Therefore, a means of killing red mites on poultry, especially chicken groups, is urgently sought.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide an improved method for preventing and controlling red mites in poultry, which not only can better kill the red mites in poultry, particularly chicken flocks, but also solves the problems of drug resistance, pesticide residue, environmental pollution and the like in the prior art.
In order to solve the technical problems, the invention adopts a technical scheme as follows:
a method for controlling red mites of poultry, said method employing feeding the poultry with a first plant essential oil composition as a feed additive and applying to the poultry a second plant essential oil composition as a spray; wherein the first plant essential oil composition comprises cinnamaldehyde, citronellal, carvacrol, eugenol, citral, linalool, and a carrier, and the second plant essential oil composition comprises cinnamaldehyde, carvacrol, eugenol, citral, peppermint oil, eucalyptus oil, and water.
In the present invention, "applied to poultry as a spray" means that the spray acts on the poultry or in the poultry's living environment in the form of a spray.
According to some preferred and specific aspects of the present invention, the first plant essential oil composition is a solid and the second plant essential oil composition is a liquid.
According to some preferred aspects of the invention, the first plant essential oil composition is added to the feed as a feed additive in an amount of 80-250 g/t. In some embodiments of the invention, the first plant essential oil composition is added to the feed as a feed additive in an amount of 80-200 g/t. In some embodiments of the present invention, the first plant essential oil composition is added as a feed additive to the feed in an amount of 100-200 g/t. In some embodiments of the present invention, the first plant essential oil composition is added as a feed additive in the feed in an amount of 120-180 g/t.
According to some preferred aspects of the present invention, the second plant essential oil composition is diluted with dilution water when sprayed as a spray, and the mass ratio of the second plant essential oil composition to the dilution water in the spray is controlled to be 1:10 to 1:150, preferably 1:20 to 1:150, more preferably 1:30 to 1: 120.
According to some preferred aspects of the present invention, the total input amount of the cinnamaldehyde, the citronellal, the carvacrol, the eugenol, the citral and the linalool in the first plant essential oil composition accounts for more than 18%, preferably more than 20%, and more preferably more than 22% of the first plant essential oil composition by mass.
According to some preferred aspects of the present invention, the total input amount of the cinnamaldehyde, the carvacrol, the eugenol, the citral, the peppermint oil and the eucalyptus oil in the second plant essential oil composition accounts for more than 25% by mass, preferably more than 28% by mass, and more preferably more than 30% by mass of the second plant essential oil composition.
According to some preferred aspects of the present invention, the first plant essential oil composition further comprises a combination of one or more selected from the group consisting of essential oil of angelica dahurica, essential oil of angelica sinensis, essential oil of orange flower, essential oil of helichrysum and essential oil of bergamot, preferably two or more, more preferably three or more, and further preferably four or more.
According to some preferred aspects of the invention, the second plant essential oil composition further comprises a combination of one or more selected from the group consisting of essential oil of rowaway, essential oil of myrrh, essential oil of dill, essential oil of birch and essential oil of nardostachys paniculata, preferably two or more, more preferably three or more, and further preferably four or more.
According to some specific and preferred aspects of the invention, the first plant essential oil composition further comprises a hydrophilic emulsifier which is sucrose fatty acid ester or tween 80 or a combination of both, a lipophilic emulsifier which is monoglyceride or propylene glycol monostearate or a combination of both.
According to some specific and preferred aspects of the invention, the second plant essential oil composition further comprises an emulsifier, a co-emulsifier, the emulsifier is one or a mixture of more of tween 80, tween 40 or RH40, and the co-emulsifier is one or a mixture of more of ethanol, glycerol or propylene glycol.
According to some preferred aspects of the invention, in the first plant essential oil composition, on a mass percentage basis, the cinnamic aldehyde is 7% -15%, the citronellal is 2% -8%, the carvacrol is 2% -6%, the eugenol is 2% -6%, the citral is 1% -3%, the linalool is 1% -3%, the angelica dahurica essential oil is 1% -3%, the angelica essential oil is 1% -3%, the orange flower essential oil is 1% -3%, the helichrysum essential oil is 1% -3%, the bergamot essential oil is 1% -3%, the hydrophilic emulsifier is 1% -3%, the lipophilic emulsifier is 1% -2%, and the carrier is 60% -78%, and the carrier is one or a mixture of several of arabic gum, beta-cyclodextrin and maltodextrin.
According to some preferred aspects of the invention, in the second plant essential oil composition, on a mass percentage basis, the cinnamic aldehyde is 10% to 17%, the carvacrol is 3% to 10%, the eugenol is 3% to 10%, the citral is 2% to 5%, the peppermint oil is 2% to 5%, the eucalyptus oil is 2% to 5%, the rosa roxburghii essential oil is 1% to 3%, the myrrh essential oil is 1% to 3%, the dill essential oil is 1% to 3%, the birch essential oil is 1% to 3%, the spikenard essential oil is 1% to 4%, the emulsifier is 0.5% to 2%, and the water is 45% to 70%.
According to some preferred aspects of the present invention, the first plant essential oil composition is prepared by: (1) weighing the components according to the formula, and mixing the essential oil components with a lipophilic emulsifier to obtain composite plant essential oil; (2) mixing the weighed carrier and hydrophilic emulsifier with water, heating, stirring and dissolving, then adding the composite plant essential oil obtained in the step (1), mixing, carrying out heat preservation and emulsification at 45-50 ℃, then carrying out homogeneous emulsification at 15-25MPa to obtain an emulsion, and carrying out spray drying to obtain a solid first plant essential oil composition; the preparation method can enable the prepared solid first plant essential oil composition to be in a microcapsule form, so that the essential oil components contained in the first plant essential oil composition are fully and uniformly distributed in each particle, and further, the essential oil components can act synergistically to enhance the effect of killing red mites.
According to some preferred aspects of the present invention, the second plant essential oil composition is prepared by: (1) weighing the components according to the formula, and mixing the emulsifier with the co-emulsifier to prepare a composite emulsifier; (2) and (2) mixing the composite emulsifier obtained in the step (1) with the weighed essential oils to obtain mixed essential oil, then dropwise adding water into the obtained mixed essential oil, stirring, and homogenizing to prepare the liquid second plant essential oil composition.
Due to the adoption of the technical scheme, compared with the prior art, the invention has the following advantages:
the invention adopts two specific essential oil formulas, one is used as a feed additive to be mixed with conventional feed to feed poultry, especially chickens, and the other is used as a spray type spraying agent to be diluted with water and then sprayed into a poultry house, thereby obtaining excellent effect of killing red mites; on one hand, the special essential oil formula components in the blood of the chicken flocks are endowed, and meanwhile, the physiological garbage (excrement, urine and the like) discharged by the chicken flocks in vitro contains the special essential oil formula components, so that the red mites sucking the blood can be inhibited from sucking the blood, can be gradually killed by the action of the special essential oil components, and meanwhile, the survival and growth of the red mites in the living environment are inhibited, and the ecological environment of a farm is improved; on the other hand, the special liquid essential oil formula components are adopted to act on poultry bodies or living environments in a spraying mode and the like, and are combined with a feeding mode, hidden red mites are quickly killed, the special liquid essential oil formula components have a relatively long-lasting effect of inhibiting the red mites, and meanwhile, the special liquid essential oil formula components have no side effect on respiratory tracts, skins and the like of the poultry, especially chickens, and can promote respiratory tract health, immunity enhancement and the like of the poultry, overcome the problems of pesticide residues, environmental pollution, drug resistance and the like in the prior art, and have important social and ecological significance for guaranteeing the safety of human and livestock products.
Detailed Description
The invention will be further elucidated with reference to specific preferred embodiment modes. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. In addition, after reading the content of the present invention, those skilled in the art can make various changes or modifications to the present invention, and these equivalents also fall within the scope defined by the present invention.
In the following embodiments, all raw materials are commercially available unless otherwise specified.
Example 1
This example provides a first plant essential oil composition comprising the following components:
8 parts of cinnamyl aldehyde, 4 parts of citronellal, 3 parts of carvacrol, 3 parts of eugenol, 2 parts of citral, 2 parts of linalool, 2 parts of angelica essential oil, 2 parts of orange flower essential oil, 1 part of helichrysum essential oil, 1 part of bergamot essential oil, 2 parts of sucrose fatty acid ester, 1 part of monoglyceride, 34 parts of Arabic gum and 33 parts of beta-cyclodextrin.
The preparation method comprises the following steps:
(1) weighing the components according to the formula, mixing, stirring and dissolving the essential oil components and monoglyceride to obtain compound plant essential oil;
(2) adding a proper amount of water into weighed Arabic gum and beta-cyclodextrin, adding sucrose fatty acid ester, heating and stirring at 30 ℃ to dissolve, adding the composite plant essential oil obtained in the step (1), and stirring at a high speed to uniformly mix;
(3) emulsifying at 50 deg.C for 1 hr, homogenizing under 20MPa for 5min with high pressure homogenizer to obtain homogeneous emulsion, and spray drying to obtain microcapsule-shaped solid first plant essential oil composition.
Example 2
This example provides a first plant essential oil composition comprising the following components:
11 parts of cinnamyl aldehyde, 3 parts of citronellal, 4 parts of carvacrol, 4 parts of eugenol, 2 parts of citral, 2 parts of linalool, 1 part of essential oil of angelica dahurica, 1 part of essential oil of angelica sinensis, 2 parts of essential oil of orange flowers, 2 parts of essential oil of helichrysum, 2 parts of essential oil of bergamot, 2 parts of sucrose fatty acid ester, 1 part of monoglyceride, 32 parts of arabic gum and 31 parts of maltodextrin.
The preparation method comprises the following steps:
(1) weighing the components according to the formula, mixing, stirring and dissolving the essential oil components and monoglyceride to obtain compound plant essential oil;
(2) adding a proper amount of water into weighed Arabic gum and maltodextrin, adding sucrose fatty acid ester, heating and stirring at 30 ℃ to dissolve, adding the composite plant essential oil obtained in the step (1), and stirring at a high speed to uniformly mix;
(3) emulsifying at 50 deg.C for 1 hr, homogenizing under 20MPa for 5min with high pressure homogenizer to obtain homogeneous emulsion, and spray drying to obtain microcapsule-shaped solid first plant essential oil composition.
Example 3
This example provides a second plant essential oil composition comprising the following components:
15 parts of cinnamaldehyde, 7 parts of carvacrol, 7 parts of eugenol, 4 parts of citral, 3 parts of peppermint oil, 3 parts of eucalyptus oil, 2 parts of essential oil of nutgrass flatsedge, 2 parts of essential oil of myrrh, 2 parts of essential oil of dill, 1 part of essential oil of birch, 1 part of essential oil of spikenard, 802 parts of tween, 1 part of propylene glycol and 50 parts of water.
The preparation method comprises the following steps:
(1) weighing the components according to the formula, and adding tween 80 into propylene glycol to be uniformly stirred to prepare a mixed emulsifier;
(2) adding the mixed emulsifier into various essential oils, and stirring uniformly to obtain mixed essential oils;
(3) dropwise adding water into the mixed essential oil obtained in the step (2) while stirring, wherein the dropwise adding speed is slow at the beginning, and the mixed essential oil is fully and uniformly stirred;
(4) and finally homogenizing in a high-pressure homogenizer to form a uniform and stable solution, namely the liquid second plant essential oil composition.
Example 4
This example provides a second plant essential oil composition comprising the following components:
13 parts of cinnamaldehyde, 4 parts of carvacrol, 4 parts of eugenol, 3 parts of citral, 3 parts of peppermint oil, 3 parts of eucalyptus oil, 1 part of essential oil of nutgrass flatsedge, 1 part of essential oil of myrrh, 2 parts of essential oil of dill, 2 parts of essential oil of birch, 2 parts of essential oil of spikenard, 2 parts of RH40 (polyoxyethylene hydrogenated castor oil), 1 part of ethanol and 59 parts of water.
The preparation method comprises the following steps:
(1) weighing the components according to the formula, putting RH40 into ethanol, and stirring uniformly to prepare a mixed emulsifier;
(2) adding the mixed emulsifier into various essential oils, and stirring uniformly to obtain mixed essential oils;
(3) dropwise adding water into the mixed essential oil obtained in the step (2) while stirring, wherein the dropwise adding speed is slow at the beginning, and the mixed essential oil is fully and uniformly stirred;
(4) and finally homogenizing in a high-pressure homogenizer to form a uniform and stable solution, namely the liquid second plant essential oil composition.
Comparative example 1
Basically, the method is the same as example 2, and only differs from the method in that the cinnamaldehyde is replaced by the conventional neem oil with acaricidal effect.
Comparative example 2
Substantially as in example 4, all essential oil components were replaced with the same amount of thymol having various bactericidal, acaricidal and like effects.
Comparative example 3
Essentially as in example 4, all essential oil components were replaced with equal amounts of cinnamaldehyde.
EXAMPLE 5 in vitro inhibitory Effect of the plant essential oil compositions of examples 1 to 4 and comparative examples 1 to 2 on Red mite
The test method comprises the following steps:
microcapsule form solid first plant essential oil composition anti-red mite test method: weighing 0.2g of the first plant essential oil composition in a solid state in a microcapsule form into a culture dish, adding about 50 red mites, covering the culture dish with a lid, and sealing the periphery with a sealing film; the death of the red mites was observed under a stereoscope and the time to death and mortality of the red mites were recorded.
The liquid second plant essential oil composition anti-red mite test method comprises the following steps: respectively weighing 1g of the liquid second plant essential oil composition, dripping into a glass bottle with a plug, diluting according to the proportion of 1:30 and 1:60 to water, uniformly adding about 50 red mites into a culture dish, spraying 0.4g of diluted liquid essential oil onto the red mites in the culture dish by using a micro sprayer, and observing and recording the death condition of the red mites under a stereoscope.
Test results
Table 1 solid first plant essential oil composition in microcapsule form%
As shown in Table 1, the plant essential oil composition of the embodiment 1-2 can kill more than 80% of red mites within 30min, and can kill all red mites within 60min, which indicates that the effect of killing the red mites is good; whereas the effect of comparative example 1 is significantly reduced.
Table 2 liquid second plant essential oil composition has a red mite inhibitory effect%
As can be seen from Table 2, the concentration of the essential oil which causes half of the red mites to die within 1 hour was judged as the appropriate dilution ratio. The liquid second plant essential oil composition is suitably diluted at a ratio of 1:60, and the effect of killing red mites of comparative examples 2 and 3 is remarkably reduced. In the case of very serious red mites, the dilution ratio of the essential oil can be properly reduced.
Example 6 selection of a certain hen farm in Henan where red mites occur for animal testing
Test animals and groups
Test group 1: the chickens were fed 150g/t of the solid first plant essential oil composition in microcapsule form of example 1 in a cocktail of chickens, the liquid second plant essential oil composition according to example 3: water was sprayed at a 1:60 dilution.
Test group 2: the chickens were fed 150g/t of the solid first plant essential oil composition in microcapsule form according to example 2 in a cocktail of chickens, the liquid second plant essential oil composition according to example 4: water was sprayed at a 1:60 dilution.
Control group 1: chickens were fed to a red mite broiler house with only 150g/t of the solid first plant essential oil composition in microcapsule form of example 2 in admixture with feed.
Control group 2: only the liquid second plant essential oil composition of example 4 was used for the red mite severe coop: water was sprayed at a 1:60 dilution.
Control group 3: the chickens were fed 150g/t of a solid first plant essential oil composition in microcapsule form according to comparative example 1 mixed with feed to a red mite severe chicken house, according to comparative example 2a liquid second plant essential oil composition: water was sprayed at a 1:60 dilution.
Red mite status was scored daily.
TABLE 3 Red mite infestation level score criteria
2 test results and analysis
2.1 Effect of Red mite Severe hen houses on Red mite treatment modalities
Table 4 effect of red mite on red mites by different methods in a severe chicken coop
As can be seen from Table 4, the red mites all died 8 days after the feed was dressed with the essential oil spray +150ppm essential oil of the invention. The red mites die little by little at the beginning, the red mites are improved in two or three days, the red mites die basically in 5 to 7 days, all the red mites are killed in 8 days, and meanwhile, chickens have no respiratory symptoms and grow normally. The acaricidal effect of the essential oil spray and 150ppm essential oil mixed material in the test group 2 is slightly better than that in the test group 1.
The chicken fed with the control group 1 mixed with the feed can completely kill the red mites after a long using time, but the killing period is obviously prolonged compared with that of the test groups 1-2.
The control group 2 can completely kill red mites after the essential oil spray is used for a longer time, but the killing period is obviously longer than that of the test groups 1-2 and is shorter than that of the control group 1.
The control group 3 adopting the essential oil spray and the essential oil mixing material of the comparative example can completely kill the red mites after long-time use, but the killing period is obviously prolonged compared with the test group 1-2, but the killing period is shorter than that of the control group 1 and is longer than that of the control group 2.
2.2 Red mite Severe hen treatment on laying hen production Performance
TABLE 5 Productivity of Red mite Setaria test groups 1-2 and control groups 1-3
And (4) conclusion: the laying performance of the laying hens in the test group 1 and the test group 2 is better, and the death and culling rate of the laying hens is reduced.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention, including any reference to the above-mentioned embodiments. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (15)
1. A method for controlling red mites of poultry, which method employs feeding the poultry with a first plant essential oil composition as a feed additive and applying a second plant essential oil composition as a spray to the poultry house; wherein the first plant essential oil composition comprises cinnamaldehyde, citronellal, carvacrol, eugenol, citral, linalool, and a carrier, the second plant essential oil composition comprises cinnamaldehyde, carvacrol, eugenol, citral, peppermint oil, eucalyptus oil, and water, the first plant essential oil composition is a solid, and the second plant essential oil composition is a liquid.
2. The method for controlling red mites of poultry according to claim 1, where in the first plant essential oil composition is added as feed additive in the feed in an amount of 80-250 g/t.
3. The method for controlling red mites of poultry as claimed in claim 1, wherein said second plant essential oil composition is diluted with dilution water at the time of spraying as a spray, and the mass ratio of said second plant essential oil composition to said dilution water in the spray is controlled to be 1:10 to 1: 150.
4. The method for controlling red mites of poultry as claimed in claim 3, wherein said second plant essential oil composition is diluted with dilution water at the time of spraying as a spray, and the mass ratio of said second plant essential oil composition to said dilution water in the spray is controlled to be 1:20-1: 150.
5. The method for controlling red mites of poultry as claimed in claim 4, wherein said second plant essential oil composition is diluted with dilution water at the time of spraying as a spray, and the mass ratio of said second plant essential oil composition to said dilution water in the spray is controlled to be 1:30-1: 120.
6. The method for controlling red mites of poultry according to claim 1, where in said first plant essential oil composition, the total input of said cinnamaldehyde, said citronellal, said carvacrol, said eugenol, said citral and said linalool is greater than 18% by weight of said first plant essential oil composition.
7. The method for controlling red mites of poultry according to claim 6, where in said first plant essential oil composition, the total input of said cinnamaldehyde, said citronellal, said carvacrol, said eugenol, said citral and said linalool is 20% or more by weight of said first plant essential oil composition.
8. The method for controlling red mites of poultry according to claim 7, where in said first plant essential oil composition, the total input of said cinnamaldehyde, said citronellal, said carvacrol, said eugenol, said citral and said linalool is greater than 22% by weight of said first plant essential oil composition.
9. The method for controlling red mites of poultry according to claim 1 or 6, where in the second plant essential oil composition, the total input of the cinnamaldehyde, the carvacrol, the eugenol, the citral, the peppermint oil and the eucalyptus oil accounts for more than 25% by weight of the second plant essential oil composition.
10. The method for controlling red mites of poultry according to claim 9, where in said second plant essential oil composition, the total charged amount of said cinnamaldehyde, said carvacrol, said eugenol, said citral, said peppermint oil, and said eucalyptus oil is greater than 28% by weight of said second plant essential oil composition.
11. The method for controlling red mites of poultry according to claim 10, where in said second plant essential oil composition, the total charged amount of said cinnamaldehyde, said carvacrol, said eugenol, said citral, said peppermint oil, and said eucalyptus oil is greater than 30% by weight of said second plant essential oil composition.
12. The method for controlling red mites of poultry according to claim 1, where said first plant essential oil composition further comprises a combination of one or more selected from angelica dahurica essential oil, angelica essential oil, orange flower essential oil, helichrysum essential oil, and bergamot essential oil; and/or the presence of a gas in the gas,
the second plant essential oil composition further comprises a combination of one or more selected from the group consisting of essential oil of Arvensara aromatica, myrrh, dill, birch and Nardostachys jatamansi.
13. The method for controlling red mites of poultry of claim 12 where said first plant essential oil composition further comprises a hydrophilic emulsifier which is sucrose fatty acid ester or tween 80 or a combination of both, a lipophilic emulsifier which is monoglyceride or propylene glycol monostearate or a combination of both; and/or the second plant essential oil composition further comprises an emulsifier and a co-emulsifier, wherein the emulsifier is one or a mixture of more of tween 80, tween 40 or RH40, and the co-emulsifier is one or a mixture of more of ethanol, glycerol or propylene glycol.
14. The method for controlling red mites of poultry as claimed in claim 13, wherein in the first plant essential oil composition, on a mass percentage basis, 7% -15% of cinnamaldehyde, 2% -8% of citronellal, 2% -6% of carvacrol, 2% -6% of eugenol, 1% -3% of citral, 1% -3% of linalool, 1% -3% of angelica essential oil, 1% -3% of orange flower essential oil, 1% -3% of helichrysum essential oil, 1% -3% of bergamot essential oil, 1% -3% of hydrophilic emulsifier, 1% -2% of lipophilic emulsifier, 60% -78% of carrier which is one or a mixture of several selected from acacia, beta-cyclodextrin and maltodextrin; and/or the presence of a gas in the gas,
the second plant essential oil composition comprises, by mass, 10% -17% of cinnamaldehyde, 3% -10% of carvacrol, 3% -10% of eugenol, 2% -5% of citral, 2% -5% of peppermint oil, 2% -5% of eucalyptus oil, 1% -3% of nutgrass flatsedge essential oil, 1% -3% of myrrh essential oil, 1% -3% of dill essential oil, 1% -3% of birch essential oil, 1% -3% of spikenard essential oil, 1% -4% of an emulsifier, 0.5% -2% of an emulsifier and 45% -70% of water.
15. The method for controlling red mites of poultry according to claim 14, where said first plant essential oil composition is prepared by: (1) weighing the components according to the formula, and mixing the essential oil components with a lipophilic emulsifier to obtain composite plant essential oil; (2) mixing the weighed carrier and hydrophilic emulsifier with water, heating, stirring and dissolving, then adding the composite plant essential oil obtained in the step (1), mixing, carrying out heat preservation and emulsification at 45-50 ℃, then carrying out homogeneous emulsification at 15-25MPa to obtain an emulsion, and carrying out spray drying to obtain a solid first plant essential oil composition; and/or the presence of a gas in the gas,
the second plant essential oil composition is prepared by the following method: (1) weighing the components according to the formula, and mixing the emulsifier with the co-emulsifier to prepare a composite emulsifier; (2) and (2) mixing the composite emulsifier obtained in the step (1) with the weighed essential oils to obtain mixed essential oil, then dropwise adding water into the obtained mixed essential oil, stirring, and homogenizing to prepare the liquid second plant essential oil composition.
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CN114699444B (en) * | 2022-03-28 | 2023-09-01 | 河南农业大学 | Traditional Chinese medicine composition for killing chicken dermatophagoides pteronyssinus and preparation method thereof |
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Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2345594A1 (en) * | 2009-03-26 | 2010-09-27 | Agrocontrol 2007, S.L | Mite composition, the rearing thereof and methods for application of the composition in biological control systems |
CN102987093A (en) * | 2012-10-29 | 2013-03-27 | 安佑(中国)动物营养研发有限公司 | Feeding plant essential oil additive as well as preparation and application of additive |
CN106489836A (en) * | 2016-10-24 | 2017-03-15 | 博白县城东祥桂猪场 | A kind of pig cultivation method of preventing and treating parasite |
CN107242361A (en) * | 2017-06-27 | 2017-10-13 | 内蒙古金河动物药业有限公司 | A kind of mixed feed additive plants essential oil particle and preparation method thereof |
CN107550922A (en) * | 2017-03-20 | 2018-01-09 | 安徽天安生物科技股份有限公司 | A kind of prescription for treating pig acarid disease |
CN109833296A (en) * | 2019-03-28 | 2019-06-04 | 佛山市正典生物技术有限公司 | Can the new merit chigger disease of prevention and control plants essential oil microemulsion formulation and preparation method thereof |
JP2020110192A (en) * | 2015-05-22 | 2020-07-27 | 石原産業株式会社 | Natural enemy insect protection device |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH1129427A (en) * | 1997-07-09 | 1999-02-02 | Cosmo Ace:Kk | Acaricide including hinoki oil or hiba arborvitae oil-containing composition as active component and controlling of acarids using the same |
CN106070202A (en) * | 2006-02-15 | 2016-11-09 | 博塔诺凯普有限公司 | The application of microencapsulated essential oils |
EP2073632A4 (en) * | 2007-03-22 | 2015-08-05 | Tyratech Inc | Synergistic pest-control compositions |
CN105494408B (en) * | 2015-11-30 | 2019-03-01 | 浙江新安化工集团股份有限公司 | A kind of Efficient insecticidal composition and its application method containing hydroprene |
-
2019
- 2019-08-01 CN CN201910707314.8A patent/CN110495420B/en active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2345594A1 (en) * | 2009-03-26 | 2010-09-27 | Agrocontrol 2007, S.L | Mite composition, the rearing thereof and methods for application of the composition in biological control systems |
CN102987093A (en) * | 2012-10-29 | 2013-03-27 | 安佑(中国)动物营养研发有限公司 | Feeding plant essential oil additive as well as preparation and application of additive |
JP2020110192A (en) * | 2015-05-22 | 2020-07-27 | 石原産業株式会社 | Natural enemy insect protection device |
CN106489836A (en) * | 2016-10-24 | 2017-03-15 | 博白县城东祥桂猪场 | A kind of pig cultivation method of preventing and treating parasite |
CN107550922A (en) * | 2017-03-20 | 2018-01-09 | 安徽天安生物科技股份有限公司 | A kind of prescription for treating pig acarid disease |
CN107242361A (en) * | 2017-06-27 | 2017-10-13 | 内蒙古金河动物药业有限公司 | A kind of mixed feed additive plants essential oil particle and preparation method thereof |
CN109833296A (en) * | 2019-03-28 | 2019-06-04 | 佛山市正典生物技术有限公司 | Can the new merit chigger disease of prevention and control plants essential oil microemulsion formulation and preparation method thereof |
Non-Patent Citations (2)
Title |
---|
多种杀虫剂与植物精油对鸡皮刺螨的体外杀灭试验;周强等;《中国家禽》;20190731;第41卷(第13期);第52-55页 * |
鸡皮刺螨防控技术研究进展;赵佳怡等;《中国家禽》;20190531;第41卷(第9期);第48-52页 * |
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