CN103417806A - Medicine for treating infectious bronchitis of chicken and preparation method thereof - Google Patents
Medicine for treating infectious bronchitis of chicken and preparation method thereof Download PDFInfo
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- CN103417806A CN103417806A CN2013103443558A CN201310344355A CN103417806A CN 103417806 A CN103417806 A CN 103417806A CN 2013103443558 A CN2013103443558 A CN 2013103443558A CN 201310344355 A CN201310344355 A CN 201310344355A CN 103417806 A CN103417806 A CN 103417806A
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Abstract
The invention discloses a medicine for treating infectious bronchitis of chicken. The medicine is prepared by the following raw materials: white mulberry root-bark, rhizoma anemarrhenae, bitter apricot seed, radix peucedani, honeysuckle, fructus forsythiae, platycodon root, liquorice, reddish orange and baical skullcap root, and can be manufactured into various medicament forms. Practice statistical data shows that the medicine has smaller side effects on poultry while achieving favorable cure rate and is subject to no remarkable undesirable reaction.
Description
Technical field
The present invention relates to a kind of veterinary drug, specially refer to a kind of medicine of take treatment infectious bronchitis of chicken prepared as raw material by Chinese herbal medicine, the invention still further relates to the preparation method of this medicine.
Background technology
Infectious bronchitis of chicken is a kind of acute height contact respiratory infectious disease of the chicken that caused by infectious bronchitis virus, and its induced factor is various, and Chinese veterinarian thinks, how because of the pathogenic heat invasion and attack, or affection of exogenous wind-cold enters inner heat-transformation, bright liquid becomes expectorant, due to impairment of purifying function of the lung.Primary disease treatment adopts antiviral Western medicine+antiviral combination medication, but country prohibites use the antiviral Western medicine in breeding process, and due to the strain difference, also each is variant for therapeutic effect, can not be satisfactory.
Summary of the invention
The objective of the invention is to overcome the deficiencies in the prior art, a kind of medicine for the treatment of infectious bronchitis of chicken is provided, this curative effect of medication is fast, short treating period, and the medicine of non-evident effect.
The preparation method that this pharmaceutical composition is provided is another goal of the invention of the present invention.
The pharmaceutical composition for the treatment of infectious bronchitis of chicken of the present invention is comprised of the crude drug of following mass parts:
Cortex Mori: 40 ~ 70 parts, the Rhizoma Anemarrhenae: 40 ~ 65 parts, Semen Armeniacae Amarum: 40 ~ 60 parts, Radix Peucedani: 45 ~ 65 parts, Flos Lonicerae: 100 ~ 120 parts, Fructus Forsythiae: 50 ~ 65g part, Radix Platycodonis: 45 ~ 60 parts, Radix Glycyrrhizae: 30 ~ 50 parts, Exocarpium Citri Rubrum: 50 ~ 70 parts, Radix Scutellariae: 80 ~ 100 parts.
The further quality proportioning of medicine of the present invention is:
Cortex Mori: 50 ~ 55 parts, the Rhizoma Anemarrhenae: 50 ~ 55 parts, Semen Armeniacae Amarum: 50 ~ 53 parts, Radix Peucedani: 50 ~ 55 parts, Flos Lonicerae: 110 ~ 115 parts, Fructus Forsythiae: 55 ~ 58g part, Radix Platycodonis: 50 ~ 53 parts, Radix Glycyrrhizae: 48 ~ 52 parts, Exocarpium Citri Rubrum: 55 ~ 58 parts, Radix Scutellariae: 90 ~ 95 parts.
The preparation method of medicine of the present invention is as follows:
The raw material of above-mentioned mass fraction is cleaned, decoct with water twice, merge decoction liquor, filter, filtrate decompression is concentrated under relative density 1-1.08(80 ℃), cold preservation 24 hours, filter, and filtrate adds sodium benzoate 0.3%, add water to 500 parts (mass parts), stir evenly, packing, sterilizing gets product.
The clear eliminating the pathogens from the lung heat of Radix Scutellariae, the Rhizoma Anemarrhenae and Cortex Mori in prescription of the present invention, cough-relieving is coughed, and is monarch drug; Flos Lonicerae and Fructus Forsythiae heat-clearing and toxic substances removing, the principal drug assistance heat clearing away, be ministerial drug; Semen Armeniacae Amarum, Exocarpium Citri Rubrum, Radix Peucedani and Radix Platycodonis preventing phlegm from forming and stopping coughing are adjuvant drug; The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, for making medicine.All medicines share, and play altogether eliminating the pathogens from the lung heat clearly, and the power of preventing phlegm from forming and stopping coughing can treat cough, dyspnea that infectious bronchitis of chicken causes, send the symptoms such as rale, mouth breathing.
The present invention is the inventor in conjunction with the clinical experience of more than 20 years, through research repeatedly, progressively improves, and a kind of curative effect of finally succeeding in developing is treated the medicine of infectious bronchitis of chicken preferably.
The pharmaceutical composition for the treatment of infectious bronchitis of chicken of the present invention, be applicable to treat avian infectious laryngotracheitis, infectious bronchitis, chronic respiratory tract disease, mouth breathing, trachea inflammation that the distemper diseases such as newcastle disease, infective rhinitis and influenza cause, large-scale application proves, curative effect is fast, good effect.
The Clinical Treatment Test of medicine of the present invention is listed below:
2012, in the chicken of raising somewhere, Yuncheng, Shanxi Province part chicken house and raiser, occurred a kind ofly to take that cough, sneeze, trachea gong sound, laying rate descend, produce abnormal-shape egg, soft-shelled egg increases the respiratory tract disease as feature.By case analyse, virus separates and finally to be defined as a kind of height contagious disease-infectious bronchitis of chicken that coronavirus causes.
Criterion of therapeutical effect:
Cure: with sick pertussis, cough, sneeze, chickling stream nose liquid, the laying hen egg production reduces, and it is standard that respiratory mucosa is the transference cures such as serosity, catarrhal inflammation.
Take a turn for the better: with sick pertussis, cough, sneeze, chickling stream nose liquid, the laying hen egg production reduces, and it is standard that respiratory mucosa is the remissions such as serosity, catarrhal inflammation.
The sick chicken number of cure rate=healing/sick chicken sum * 100%
Effective percentage=(the sick chicken number of the healing+disease that takes a turn for the better chicken number)/sick chicken sum * 100%
Diagnostic criteria:
Analyse and find, in nasal cavity, trachea, bronchus, faint yellow translucent serosity, mucus exudate are arranged as seen by case, what the course of disease was slightly long becomes caseous substance and forms embolus.Air bag may be muddy or contains caseous exudate.The bird inlay follicle congested, hemorrhage or the distortion; Fallopian tube is short and thick, plump, contrafluxion, necrosis, and visible renomegaly, pale, urate deposition in renal tubules and expanding, kidney is graniphyric, ureter urate deposition and chap.Also there is the urate of deposition on the heart, liver surface like one deck bloom.The virus separation finally is defined as a kind of height contagious disease-infectious bronchitis of chicken that coronavirus causes.
By this infectious bronchitis of chicken of Drug therapy of the present invention, the Chinese medicine of following portions by weight of take is crude drug, Cortex Mori 60g, Rhizoma Anemarrhenae 50g, Semen Armeniacae Amarum 50g, Radix Peucedani 60g, Flos Lonicerae 120g, Fructus Forsythiae 60g, Radix Platycodonis 50g, Radix Glycyrrhizae 40g, Exocarpium Citri Rubrum 60g, Radix Scutellariae 90g, above ten flavor medicines, through decocting, concentrate and make oral liquid.
Take 10% amoxicillin soluble powder as control drug; It is subjects that the chicken house of take has been made a definite diagnosis 2480 ill chickens, wherein takes medicine of the present invention for 1240, takes control drug for another 1240; The therapeutic dose of amoxicillin is to mix 5 gram medicine powder in every 20 kilograms of feedstuffs; The oral solutions therapeutic dose is to mix 500 jin of water in every 100 jin of water, is used in conjunction 5 days.Observation and comparison trial drug and the control drug therapeutic effect to infectious bronchitis of chicken.Result of the test is in Table 1.
Clinical practice experimental results show that, the cure rate of medicine of the present invention reaches 89.92%, improvement rate reaches 9.68%, effective percentage reaches 99.6%, effect Epidemiological Analysis comparison by statistics with control drug, all without significant difference, illustrate that medicine of the present invention is when having good cure rate, birds is had to less side effect, and without obvious adverse reaction.
The specific embodiment
Below in conjunction with implementing, the present invention is described in further detail, but does not form any limitation of the invention.
Embodiment 1
Prepare raw material according to following weight: Cortex Mori: 41kg, the Rhizoma Anemarrhenae: 41 kg, Semen Armeniacae Amarum: 41 kg, Radix Peucedani: 46 kg, Flos Lonicerae: 119 kg, Fructus Forsythiae: 64g kg, Radix Platycodonis: 59 kg, Radix Glycyrrhizae: 49kg, Exocarpium Citri Rubrum: 69 kg, Radix Scutellariae: 99 kg.Described raw material is decocted with water to twice, merge decoction liquor, filter, filtrate decompression is concentrated into relative density 1.01(80 ℃), cold preservation 24 hours, filter, and filtrate adds sodium benzoate 0.3%, adds water to 500 kg, stirs evenly packing, sterilizing and get final product.
Embodiment 2
Prepare raw material according to following weight: Cortex Mori: 69kg, the Rhizoma Anemarrhenae: 64 kg, Semen Armeniacae Amarum: 59kg, Radix Peucedani: 64kg, Flos Lonicerae: 101 kg, Fructus Forsythiae: 51g kg, Radix Platycodonis: 46 kg, Radix Glycyrrhizae: 31 kg, Exocarpium Citri Rubrum: 51 kg, Radix Scutellariae: 81kg.Described raw material is decocted with water to twice, merge decoction liquor, filter, filtrate decompression is concentrated into relative density 1.06(80 ℃), cold preservation 24 hours, filter, and filtrate adds sodium benzoate 0.3%, adds water to 500 kg, stirs evenly packing, sterilizing and get final product.
Claims (3)
1. a medicine for the treatment of infectious bronchitis of chicken is characterized in that it is that crude drug by following mass parts makes:
Cortex Mori: 40 ~ 70 parts, the Rhizoma Anemarrhenae: 40 ~ 65 parts, Semen Armeniacae Amarum: 40 ~ 60 parts, Radix Peucedani: 45 ~ 65 parts, Flos Lonicerae: 100 ~ 120 parts, Fructus Forsythiae: 50 ~ 65g part, Radix Platycodonis: 45 ~ 60 parts, Radix Glycyrrhizae: 30 ~ 50 parts, Exocarpium Citri Rubrum: 50 ~ 70 parts, Radix Scutellariae: 80 ~ 100 parts.
2. the medicine for the treatment of infectious bronchitis of chicken according to claim 1 is characterized in that it is that crude drug by following mass parts makes:
Cortex Mori: 50 ~ 55 parts, the Rhizoma Anemarrhenae: 50 ~ 55 parts, Semen Armeniacae Amarum: 50 ~ 53 parts, Radix Peucedani: 50 ~ 55 parts, Flos Lonicerae: 110 ~ 115 parts, Fructus Forsythiae: 55 ~ 58g part, Radix Platycodonis: 50 ~ 53 parts, Radix Glycyrrhizae: 48 ~ 52 parts, Exocarpium Citri Rubrum: 55 ~ 58 parts, Radix Scutellariae: 90 ~ 95 parts.
3. according to the preparation method of claim 1 or 2 described medicine, it is characterized in that comprising the following steps: the raw material of above-mentioned mass fraction is cleaned, decoct with water twice, merge decoction liquor, filter, filtrate decompression is concentrated under relative density 1-1.08(80 ℃), cold preservation 24 hours, filter, filtrate adds sodium benzoate 0.3%, adds water to 500 parts (mass parts), stirs evenly, packing, sterilizing gets product.
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| CN2013103443558A CN103417806A (en) | 2013-08-09 | 2013-08-09 | Medicine for treating infectious bronchitis of chicken and preparation method thereof |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105456362A (en) * | 2015-12-23 | 2016-04-06 | 青岛农业大学 | Mixture for treating chicken infectious bronchitis and preparation method thereof |
| CN105535720A (en) * | 2015-09-07 | 2016-05-04 | 容县祥益农牧有限公司 | Chinese herbal medicinal composition for preventing and treating chick bronchitis, and preparation method thereof |
| CN105998483A (en) * | 2016-06-27 | 2016-10-12 | 瓮安县鸿黔农产品开发有限责任公司 | Medicine for treating chicken rhinitis and making method thereof |
| CN106344792A (en) * | 2016-10-17 | 2017-01-25 | 安庆市柯旷动物药业有限公司 | Traditional Chinese medicine compound for removing heat from the lung to relieve cough of livestock |
| CN106417972A (en) * | 2016-09-30 | 2017-02-22 | 安徽华澳生物技术有限公司 | Feed capable of preventing chicken air sacculitis |
| CN106421305A (en) * | 2016-09-30 | 2017-02-22 | 安徽华澳生物技术有限公司 | Medicament for preventing and controlling avian airsacculitis |
| CN109395039A (en) * | 2018-12-11 | 2019-03-01 | 郑州赛科药业科技有限公司 | Chinese medicine composition and preparation method thereof for treating mycoplasma gallinarum |
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| CN101209329A (en) * | 2006-12-25 | 2008-07-02 | 天津市润拓生物技术有限公司 | Chinese medicinal oral liquid with heat-clearing and detoxication, lung-heat-clearing and cough-relieving efficacy |
| CN102552653A (en) * | 2010-12-09 | 2012-07-11 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicinal composition with phlegm reducing and cough relieving functions and preparation method thereof |
-
2013
- 2013-08-09 CN CN2013103443558A patent/CN103417806A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101209329A (en) * | 2006-12-25 | 2008-07-02 | 天津市润拓生物技术有限公司 | Chinese medicinal oral liquid with heat-clearing and detoxication, lung-heat-clearing and cough-relieving efficacy |
| CN102552653A (en) * | 2010-12-09 | 2012-07-11 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicinal composition with phlegm reducing and cough relieving functions and preparation method thereof |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105535720A (en) * | 2015-09-07 | 2016-05-04 | 容县祥益农牧有限公司 | Chinese herbal medicinal composition for preventing and treating chick bronchitis, and preparation method thereof |
| CN105456362A (en) * | 2015-12-23 | 2016-04-06 | 青岛农业大学 | Mixture for treating chicken infectious bronchitis and preparation method thereof |
| CN105456362B (en) * | 2015-12-23 | 2020-12-04 | 青岛农业大学 | Mixture for treating infectious bronchitis of chicken and preparation method thereof |
| CN105998483A (en) * | 2016-06-27 | 2016-10-12 | 瓮安县鸿黔农产品开发有限责任公司 | Medicine for treating chicken rhinitis and making method thereof |
| CN106417972A (en) * | 2016-09-30 | 2017-02-22 | 安徽华澳生物技术有限公司 | Feed capable of preventing chicken air sacculitis |
| CN106421305A (en) * | 2016-09-30 | 2017-02-22 | 安徽华澳生物技术有限公司 | Medicament for preventing and controlling avian airsacculitis |
| CN106344792A (en) * | 2016-10-17 | 2017-01-25 | 安庆市柯旷动物药业有限公司 | Traditional Chinese medicine compound for removing heat from the lung to relieve cough of livestock |
| CN109395039A (en) * | 2018-12-11 | 2019-03-01 | 郑州赛科药业科技有限公司 | Chinese medicine composition and preparation method thereof for treating mycoplasma gallinarum |
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Application publication date: 20131204 |